Kristina Nilsson Ekdahl

The Cellular Response Capacity as Diagnostic Head Start in Neutrophil Endotoxemia Sensing

Messerer, David Alexander Christian; Mohamed, Adam Omar Khalaf; Wohlgemuth, Lisa; Vidoni, Laura et al.

Part of The FASEB Journal, 2026

• DOI for The Cellular Response Capacity as Diagnostic Head Start in Neutrophil Endotoxemia Sensing
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A new principle to attenuate ischemia-reperfusion injury in kidney transplantation

Biglarnia, Ali-Reza; Teramura, Yuji; Asif, Sana; Dührkop, Claudia et al.

Part of American Journal of Transplantation, p. 263-275, 2026

• DOI for A new principle to attenuate ischemia-reperfusion injury in kidney transplantation
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Native C3 is activated without proteolytic cleavage by transformation to C3(H2O) on phospholipid-scrambled cell membranes

Eikrem, David; Manivel, Vivek Anand; Whittaker, Jacob; Hamad, Osama A. et al.

Part of Frontiers in Immunology, 2025

• DOI for Native C3 is activated without proteolytic cleavage by transformation to C3(H2O) on phospholipid-scrambled cell membranes
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The blood response to subway-derived iron nanoparticles

Ekdahl, Kristina N.; Monie, Lisa; Juárez-Facio, Ana T.; Olofsson, Ulf et al.

Part of Environmental Toxicology and Pharmacology, 2025

• DOI for The blood response to subway-derived iron nanoparticles
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A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile

Lindelöf, Linnea; Rantapää-Dahlqvist, Solbritt; Lundtoft, Christian; Sandling, Johanna K. et al.

Part of Journal of Autoimmunity, 2024

• DOI for A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile
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The Cellular Response Capacity as Diagnostic Head Start in Neutrophil Endotoxemia Sensing

Messerer, David Alexander Christian; Mohamed, Adam Omar Khalaf; Wohlgemuth, Lisa; Vidoni, Laura et al.

Part of The FASEB Journal, 2026

• DOI for The Cellular Response Capacity as Diagnostic Head Start in Neutrophil Endotoxemia Sensing
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A new principle to attenuate ischemia-reperfusion injury in kidney transplantation

Biglarnia, Ali-Reza; Teramura, Yuji; Asif, Sana; Dührkop, Claudia et al.

Part of American Journal of Transplantation, p. 263-275, 2026

• DOI for A new principle to attenuate ischemia-reperfusion injury in kidney transplantation
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Native C3 is activated without proteolytic cleavage by transformation to C3(H2O) on phospholipid-scrambled cell membranes

Eikrem, David; Manivel, Vivek Anand; Whittaker, Jacob; Hamad, Osama A. et al.

Part of Frontiers in Immunology, 2025

• DOI for Native C3 is activated without proteolytic cleavage by transformation to C3(H2O) on phospholipid-scrambled cell membranes
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The blood response to subway-derived iron nanoparticles

Ekdahl, Kristina N.; Monie, Lisa; Juárez-Facio, Ana T.; Olofsson, Ulf et al.

Part of Environmental Toxicology and Pharmacology, 2025

• DOI for The blood response to subway-derived iron nanoparticles
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A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile

Lindelöf, Linnea; Rantapää-Dahlqvist, Solbritt; Lundtoft, Christian; Sandling, Johanna K. et al.

Part of Journal of Autoimmunity, 2024

• DOI for A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile
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Stent coating containing a charged silane coupling agent that regulates protein adsorption to confer antithrombotic and cell-adhesion properties

Inuzuka, Naoki; Shobayashi, Yasuhiro; Tateshima, Satoshi; Sato, Yuya et al.

Part of Scientific Reports, 2024

• DOI for Stent coating containing a charged silane coupling agent that regulates protein adsorption to confer antithrombotic and cell-adhesion properties
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Surface modulation of extracellular vesicles with cell-penetrating peptide-conjugated lipids for improvement of intracellular delivery to endothelial cells

Huang, Tianwei; Sato, Yuya; Kuramochi, Akiko; Ohba, Yoshio et al.

Part of Regenerative Therapy, p. 90-98, 2023

• DOI for Surface modulation of extracellular vesicles with cell-penetrating peptide-conjugated lipids for improvement of intracellular delivery to endothelial cells
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Regulation of the innate immune system by fragmented heparin-conjugated lipids on lipid bilayered membranes in vitro

Adler, Anna; Fritsch, Marlene; Fromell, Karin; Leneweit, Gero et al.

Part of Journal of materials chemistry. B, p. 11121-11134, 2023

• DOI for Regulation of the innate immune system by fragmented heparin-conjugated lipids on lipid bilayered membranes in vitro
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Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?

Mannes, Marco; Halbgebauer, Rebecca; Wohlgemuth, Lisa; Messerer, David Alexander Christian et al.

Part of Journal of Innate Immunity, p. 412-427, 2023

• DOI for Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?
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How COVID-19 and other pathological conditions and medical treatments activate our intravascular innate immune system

Nilsson, Bo; Eriksson, Oskar; Fromell, Karin; Persson, Barbro et al.

Part of Frontiers in Immunology, 2023

• DOI for How COVID-19 and other pathological conditions and medical treatments activate our intravascular innate immune system
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Activation of the Complement and Coagulation Systems in the Small Airways in Asthma

Kokelj, Spela; Östling, Jörgen; Fromell, Karin; Vanfleteren, Lowie E. G. W. et al.

Part of Respiration, p. 621-631, 2023

• DOI for Activation of the Complement and Coagulation Systems in the Small Airways in Asthma
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Complement and platelets: prothrombotic cell activation requires membrane attack complex-induced release of danger signals

Mannes, Marco; Pechtl, Veronika; Hafner, Susanne; Dopler, Arthur et al.

Part of Blood Advances, p. 6367-6380, 2023

• DOI for Complement and platelets: prothrombotic cell activation requires membrane attack complex-induced release of danger signals
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Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model

Spiegelburg, Doreen Tabea; Mannes, Marco; Schultze, Anke; Scheibenberger, Frieder et al.

Part of PLOS ONE, 2023

• DOI for Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model
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Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19

Hultström, Michael; Frithiof, Robert; Grip, Jonathan; Lindelöf, Linnea et al.

Part of Nature Immunology, p. 861-864, 2022

• DOI for Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19

Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions

Suzuki, Haruna; Adler, Anna; Huang, Tianwei; Kuramochi, Akiko et al.

Part of Science and Technology of Advanced Materials, p. 845-857, 2022

• DOI for Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions
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Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins

Adler, Anna; Inoue, Yuuki; Nilsson Ekdahl, Kristina; Baba, Teruhiko et al.

Part of Journal of materials chemistry. B, p. 2512-2522, 2022

• DOI for Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins

Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation

Gerogianni, Alexandra; Dimitrov, Jordan D.; Zarantonello, Alessandra; Poillerat, Victoria et al.

Part of Frontiers in Immunology, 2022

• DOI for Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation
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A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein

Adler, Anna; Manivel, Vivek Anand; Fromell, Karin; Teramura, Yuji et al.

Part of Frontiers in Immunology, 2022

• DOI for A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein
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Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis

Wohlgemuth, Lisa; Stratmann, Alexander Elias Paul; Muennich, Frederik; Bernhard, Stefan et al.

Part of Cells, 2022

• DOI for Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis
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The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System

Lipcsey, Miklós; Persson, Barbro; Eriksson, Oskar; Blom, Anna M. et al.

Part of Frontiers in Immunology, 2021

• DOI for The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System
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Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis

Goto, Junko; Forsberg, Ulf; Jonsson, Per; Matsuda, Kenichi et al.

Part of International Journal of Artificial Organs, p. 539-550, 2021

• DOI for Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis
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Hemocompatibility of Nanotitania-Nanocellulose Hybrid Materials

Svensson, Fredric G.; Manivel, Vivek Anand; Seisenbaeva, Gulaim A.; Kessler, Vadim G. et al.

Part of Nanomaterials, 2021

• DOI for Hemocompatibility of Nanotitania-Nanocellulose Hybrid Materials
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Smoking induces sex-specific changes in the small airway proteome

Kokelj, Spela; Ostling, Jorgen; Georgi, Benjamin; Fromell, Karin et al.

Part of Respiratory Research, 2021

• DOI for Smoking induces sex-specific changes in the small airway proteome
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Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions

Bernhard, Stefan; Hug, Stefan; Stratmann, Alexander Elias Paul; Erber, Maike et al.

Part of Journal of Innate Immunity, p. 225-241, 2021

• DOI for Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions
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Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions

Adler, Anna; Inoue, Yuuki; Sato, Yuya; Ishihara, Kazuhiko et al.

Part of Biomaterials Science, p. 5854-5867, 2021

• DOI for Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions

The Complex Relationship between C4b-Binding Protein, Warfarin, and Antiphospholipid Antibodies

Grosso, Giorgia; Sandholm, Kerstin; Antovic, Aleksandra; Gunnarsson, Iva et al.

Part of Thrombosis and Haemostasis, p. 1299-1309, 2021

• DOI for The Complex Relationship between C4b-Binding Protein, Warfarin, and Antiphospholipid Antibodies

Cell Surface Functionalization with Heparin-Conjugated Lipid to Suppress Blood Activation

Asawa, Kenta; Ishihara, Kazuhiko; Nilsson Ekdahl, Kristina; Nilsson, Bo et al.

Part of Advanced Functional Materials, 2021

• DOI for Cell Surface Functionalization with Heparin-Conjugated Lipid to Suppress Blood Activation

Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells

Rangasami, Vignesh K.; Nawale, Ganesh N.; Asawa, Kenta; Kadekar, Sandeep et al.

Part of Biomacromolecules, p. 1980-1989, 2021

• DOI for Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells
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Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids

Sato, Yuya; Asawa, Kenta; Huang, Tianwei; Noiri, Makoto et al.

Part of Langmuir, p. 9711-9723, 2021

• DOI for Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids

Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients

Eriksson, Oskar; Hultström, Michael; Persson, Barbro; Lipcsey, Miklós et al.

Part of Thrombosis and Haemostasis, p. 1720-1724, 2020

• DOI for Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients

Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients

Eriksson, Oskar; Hultström, Michael; Persson, Barbro; Lipcsey, Miklós et al.

Part of Thrombosis and haemostasis, p. 1720-1724, 2020

Poly(2-aminoethyl methacrylate)-based polyampholyte brush surface with carboxylic groups to improve blood compatibility

Azuma, Tomoyuki; Matsushita, Taishi; Manivel, Vivek Anand; Nilsson Ekdahl, Kristina et al.

Part of Journal of Biomaterials Science. Polymer Edition, p. 679-693, 2020

• DOI for Poly(2-aminoethyl methacrylate)-based polyampholyte brush surface with carboxylic groups to improve blood compatibility

Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock

Halbgebauer, Rebecca; Karasu, Ebru; Braun, Christian K.; Palmer, Annette et al.

Part of Frontiers in Immunology, 2020

• DOI for Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock
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Complement deposition, C4d, on platelets is associated with vascular events in systemic lupus erythematosus

Svenungsson, Elisabet; Gustafsson, Johanna T.; Grosso, Giorgia; Rossides, Marios et al.

Part of Rheumatology, p. 3264-3274, 2020

• DOI for Complement deposition, C4d, on platelets is associated with vascular events in systemic lupus erythematosus
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Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity

Messerer, David Alexander Christian; Vidoni, Laura; Erber, Maike; Stratmann, Alexander Elias Paul et al.

Part of Frontiers in Immunology, 2020

• DOI for Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity
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Assessment of the Role of C3(H2O) in the Alternative Pathway

Fromell, Karin; Adler, Anna; Åman, Amanda; Manivel, Vivek Anand et al.

Part of Frontiers in Immunology, 2020

• DOI for Assessment of the Role of C3(H2O) in the Alternative Pathway
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Celiac disease and complement activation in response to Streptococcus pneumoniae

Tjernberg, Anna Rockert; Woksepp, Hanna; Sandholm, Kerstin; Johansson, Marcus et al.

Part of European Journal of Pediatrics, p. 133-140, 2020

• DOI for Celiac disease and complement activation in response to Streptococcus pneumoniae
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Discrepancies in plasma levels of complement components measured by a newly introduced commercially available magnetic bead technique compared to presently available clinical reference intervals

Sandholm, Kerstin; Carlsson, Hanna; Persson, Barbro; Skattum, Lillemor et al.

Part of Scandinavian Journal of Immunology, 2020

• DOI for Discrepancies in plasma levels of complement components measured by a newly introduced commercially available magnetic bead technique compared to presently available clinical reference intervals

Potential of Cell Surface Engineering with Biocompatible Polymers for Biomedical Applications

Teramura, Yuji; Nilsson Ekdahl, Kristina; Fromell, Karin; Nilsson, Bo et al.

Part of Langmuir, p. 12088-12106, 2020

• DOI for Potential of Cell Surface Engineering with Biocompatible Polymers for Biomedical Applications

C1q recognizes antigen-bound IgG in a curvature-dependent manner

Zeuthen, Christina M.; Shahrokhtash, Ali; Fromell, Karin; Nilsson Ekdahl, Kristina et al.

Part of Nano Reseach, p. 1651-1658, 2020

• DOI for C1q recognizes antigen-bound IgG in a curvature-dependent manner

Identification of Metal-Binding Peptides and Their Conjugation onto Nanoparticles of Superparamagnetic Iron Oxides and Liposomes

Kodama, Tomonobu; Yoshihara, Akifumi; Goel, Isha; Sekino, Masaki et al.

Part of ACS Applied Materials and Interfaces, p. 24623-24634, 2020

• DOI for Identification of Metal-Binding Peptides and Their Conjugation onto Nanoparticles of Superparamagnetic Iron Oxides and Liposomes

Promotion of cell membrane fusion by cell-cell attachment through cell surface modification with functional peptide-PEG-lipids

Yoshihara, Akifumi; Watanabe, Sayumi; Goel, Isha; Ishihara, Kazuhiko et al.

Part of Biomaterials, 2020

• DOI for Promotion of cell membrane fusion by cell-cell attachment through cell surface modification with functional peptide-PEG-lipids

Apolipoprotein E Triggers Complement Activation in Joint Synovial Fluid of Rheumatoid Arthritis Patients by Binding C1q

Vogt, Leonie M.; Kwasniewicz, Ewa; Talens, Simone; Scavenius, Carsten et al.

Part of Journal of Immunology, p. 2779-2790, 2020

• DOI for Apolipoprotein E Triggers Complement Activation in Joint Synovial Fluid of Rheumatoid Arthritis Patients by Binding C1q

Complement activation in individuals with previous subclinical Lyme borreliosis and patients with previous Lyme neuroborreliosis

Carlsson, Hanna; Sandholm, Kerstin; Haddish, Haben Woldu; Brudin, Lars et al.

Part of European Journal of Clinical Microbiology and Infectious Diseases, p. 855-862, 2020

• DOI for Complement activation in individuals with previous subclinical Lyme borreliosis and patients with previous Lyme neuroborreliosis
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Complement activation in cerebrospinal fluid in clinically isolated syndrome and early stages of relapsing remitting multiple sclerosis

Hakansson, Irene; Ernerudh, Jan; Vrethem, Magnus; Dahle, Charlotte et al.

Part of Journal of Neuroimmunology, 2020

• DOI for Complement activation in cerebrospinal fluid in clinically isolated syndrome and early stages of relapsing remitting multiple sclerosis

Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use

Sandholm, Kerstin; Persson, Barbro; Skattum, Lillemor; Eggertsen, Gosta et al.

Part of Frontiers in Immunology, 2019

• DOI for Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use
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Optimization of Islet Microencapsulation with Thin Polymer Membranes for Long-Term Stability

Toda, Shota; Fattah, Artin; Asawa, Kenta; Nakamura, Naoko et al.

Part of Micromachines, 2019

• DOI for Optimization of Islet Microencapsulation with Thin Polymer Membranes for Long-Term Stability
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Validation of an MPC polymer coating to attenuate surface- induced cross-talk between the complement and coagulation systems in whole blood in in vitro and in vivo models

Asif, Sana; Asawa, Kenta; Yuuki, Inoue; Ishihara, Kazuhiko et al.

Part of Macromolecular Bioscience, 2019

• DOI for Validation of an MPC polymer coating to attenuate surface- induced cross-talk between the complement and coagulation systems in whole blood in in vitro and in vivo models

Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium

Noiri, Makoto; Asawa, Kenta; Okada, Naoya; Kodama, Tomonobu et al.

Part of Journal of Biomedical Materials Research. Part A, p. 1779-1792, 2019

• DOI for Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium

Is generation of C3(H₂O) necessary for activation of the alternative pathway in real life?

Nilsson Ekdahl, Kristina; Mohlin, Camilla; Adler, Anna; Åman, Amanda et al.

Part of Molecular Immunology, p. 353-361, 2019

• DOI for Is generation of C3(H₂O) necessary for activation of the alternative pathway in real life?
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The lectin pathway of complement and the contact/kallikrein system are integrated

Fromell, Karin; Dührkop, Claudia; Kozarcanin, Huda; Johansson, Ulrika et al.

Part of Molecular Immunology, p. 151-152, 2018

• DOI for The lectin pathway of complement and the contact/kallikrein system are integrated

Generation of an alternative pathway convertase by contact-activated C3 is dependent on the conformation of C3

Fromell, Karin; Johansson, Ulrika; Dührkop, Claudia; Adler, Anna et al.

Part of Molecular Immunology, p. 193-193, 2018

• DOI for Generation of an alternative pathway convertase by contact-activated C3 is dependent on the conformation of C3

PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

van Griensven, Martijn; Ricklin, Daniel; Denk, Stephanie; Halbgebauer, Rebecca et al.

Part of Shock, p. 117-118, 2018

• DOI for PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

Is the polarized secretion of complement factor H of importance in age-related macular degeneration?

Mohlin, Camilla; Petrus-Reurer, Sandra; Lanner, Fredrik; Sandholm, Kerstin et al.

Part of Investigative Ophthalmology and Visual Science, 2018

Shiga toxin 2a binds antithrombin and heparin, but does not directly activate platelets

Knabl, Ludwig; Berktold, Michael; Hamad, Osama A.; Fromell, Karin et al.

Part of International Journal of Medical Microbiology, p. 969-976, 2018

• DOI for Shiga toxin 2a binds antithrombin and heparin, but does not directly activate platelets

Development and evaluation of cationic amphiphilic antimicrobial 2,5-diketopiperazines

Labriere, Christophe; Kondori, Nahid; Caous, Josefin Seth; Boomgaren, Marc et al.

Part of Journal of Peptide Science, 2018

• DOI for Development and evaluation of cationic amphiphilic antimicrobial 2,5-diketopiperazines

A model to study complement involvement in experimental retinal degeneration

Mohlin, Camilla; Sandholm, Kerstin; Kvanta, Anders; Nilsson Ekdahl, Kristina et al.

Part of Upsala Journal of Medical Sciences, p. 28-42, 2018

• DOI for A model to study complement involvement in experimental retinal degeneration
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Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles.

Nilsson Ekdahl, Kristina; Davoodpour, Padideh; Ekstrand-Hammarström, Barbro; Fromell, Karin et al.

Part of Nanomedicine, p. 735-744, 2018

• DOI for Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles.

Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility

Fromell, Karin; Yang, Yi; Nilsson Ekdahl, Kristina; Nilsson, Bo et al.

Part of Biointerphases, 2017

• DOI for Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility
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Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Seisenbaeva, Gulaim A.; Fromell, Karin; Vinogradov, Vasiliy V.; Terekhov, Aleksey N. et al.

Part of Scientific Reports, 2017

• DOI for Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins
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Control of IBMIR induced by fresh and cryopreserved hepatocytes by low molecular weight dextran sulfate

Gustafson, Elisabet; Asif, Sana; Kozarcanin, Huda; Meurling, Staffan et al.

Part of Cell Transplantation, p. 71-81, 2017

• DOI for Control of IBMIR induced by fresh and cryopreserved hepatocytes by low molecular weight dextran sulfate
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Forms of contact-activated C3 associated with AP convertase formation

Fromell, Karin; Dührkop, Claudia; Johansson, Ulrika; Nilsson Ekdahl, Kristina et al.

Part of Molecular Immunology, p. 141-141, 2017

• DOI for Forms of contact-activated C3 associated with AP convertase formation

Cell Adhesion Induced Using Surface Modification with Cell-Penetrating Peptide-Conjugated Poly(ethylene glycol)-Lipid: A New Cell Glue for 3D Cell-Based Structures

Teramura, Yuji; Asif, Sana; Nilsson Ekdahl, Kristina; Gustafson, Elisabet K. et al.

Part of ACS Applied Materials and Interfaces, p. 244-254, 2017

• DOI for Cell Adhesion Induced Using Surface Modification with Cell-Penetrating Peptide-Conjugated Poly(ethylene glycol)-Lipid: A New Cell Glue for 3D Cell-Based Structures

The link between morphology and complement in ocular disease

Mohlin, Camilla; Sandholm, Kerstin; Nilsson Ekdahl, Kristina; Nilsson, Bo

Part of Molecular Immunology, p. 84-99, 2017

• DOI for The link between morphology and complement in ocular disease

Properdin binding to complement activating surfaces depends on initial C3b deposition

Harboe, Morten; Johnson, Christina; Nymo, Stig; Ekholt, Karin et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2017

• DOI for Properdin binding to complement activating surfaces depends on initial C3b deposition

Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina

Mohlin, C.; Petrus-Reurer, S.; Lanner, F.; Sandholm, K. et al.

Part of Molecular Immunology, p. 162-163, 2017

• DOI for Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina

A protective role of complement regulators linked to a PEG phospholipid construct in reducing ischemic reperfusion injury in transplantation

Nilsson, Bo; Asif, Sana; Ekdahl N., Kristina; Manell, Elin et al.

Part of Molecular Immunology, p. 208-208, 2017

• DOI for A protective role of complement regulators linked to a PEG phospholipid construct in reducing ischemic reperfusion injury in transplantation

Evidence of contact activation in patients suffering from ST-elevation myocardial infarction

Christensen, Kjeld; Kozarcanin, Huda; Ekdahl, Kristina N.; Nilsson, Bo

Part of Thrombosis Research, p. 158-162, 2016

• DOI for Evidence of contact activation in patients suffering from ST-elevation myocardial infarction

The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation

Kozarcanin, Huda; Lood, Christian; Munthe-Fog, Lea; Sandholm, Kerstin et al.

Part of Journal of Thrombosis and Haemostasis, p. 531-545, 2016

• DOI for The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation

A hybrid of cells and pancreatic islets toward a new bioartificial pancreas

Termaura, Yuji; Nilsson Ekdahl, Kristina; Barbu, Andreea

Part of Regenerative Therapy, p. 68-74, 2016

Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood

Huang, Shan; Engberg, Anna E.; Jonsson, Nina; Sandholm, Kerstin et al.

Part of Biomaterials, p. 111-119, 2016

• DOI for Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood

Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function

Lindblom, Rickard; Aeinehband, Shahin; Ström, Mikael; Al Nimer, Faiez et al.

Part of Clinical Immunology, p. 89-95, 2016

• DOI for Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function
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Heparinization of cell surfaces with short pepetide-conjugated PEG-lipid regulates thromboinflammation in thransplantation of human MSCs and hepatocytes

Asif, Sana; Ekdahl, Kristina N; Fromell, Karin; Gustafson, Elisabet et al.

Part of Acta Biomaterialia, p. 194-205, 2016

• DOI for Heparinization of cell surfaces with short pepetide-conjugated PEG-lipid regulates thromboinflammation in thransplantation of human MSCs and hepatocytes

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

Nilsson Ekdahl, Kristina; Teramura, Yuji; Hamad, Osama A.; Asif, Sana et al.

Part of Immunological Reviews, p. 245-269, 2016

• DOI for Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

Development and characterization of an innovtive heparin coating to stabilize and protect liposomes against adverse immune reactions

Duehrkop, Claudia; Leneweit, Gero; Heyder, Christoph; Fromell, Karin et al.

Part of Colloids and Surfaces B, p. 576-583, 2016

• DOI for Development and characterization of an innovtive heparin coating to stabilize and protect liposomes against adverse immune reactions

Complement inhibition in biomaterial- and biosurface-induced thromboinflammation

Ekdahl, Kristina N.; Huang, Shan; Nilsson, Bo; Teramura, Yuji

Part of Seminars in Immunology, p. 268-277, 2016

• DOI for Complement inhibition in biomaterial- and biosurface-induced thromboinflammation

Molecular modelling showed optimal fit between TSR5 in trimeric properdin and C345C in the C3b moiety for stabilization of the alternative convertase, whereas binding to molecular patterns in myeloperoxidase, endothelial cells and Neisseria meningitides was indirectly mediated by initial C3 activation

Harboe, Morten; Johnson, Christina; Nymo, Stig; Ekholt, Karin et al.

Part of Immunobiology, p. 1205-1205, 2016

• DOI for Molecular modelling showed optimal fit between TSR5 in trimeric properdin and C345C in the C3b moiety for stabilization of the alternative convertase, whereas binding to molecular patterns in myeloperoxidase, endothelial cells and Neisseria meningitides was indirectly mediated by initial C3 activation

The lectin complement pathway inhibitor MAP-1 is an upstream regulator of the coagulation cascade

Skjoedt, Mikkel-Ole; Pavlov, Vasile; Kozarcanin, Huda; Willer, Anton et al.

Part of Immunobiology, p. 1209-1209, 2016

• DOI for The lectin complement pathway inhibitor MAP-1 is an upstream regulator of the coagulation cascade

Contact activation of C3 enables tethering between activated platelets and polymorphonuclear leukocytes via CD11b/CD18

Hamad, Osama A.; Mitroulis, Ioannis; Fromell, Karin; Kozarcanin, Huda et al.

Part of Thrombosis and Haemostasis, p. 1207-1217, 2015

• DOI for Contact activation of C3 enables tethering between activated platelets and polymorphonuclear leukocytes via CD11b/CD18

Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response

Lindblom, Rickard P. F.; Berg, Alexander; Strom, Mikael; Aeinehband, Shahin et al.

Part of Journal of Neuroinflammation, 2015

• DOI for Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response
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Contact activation of C3 enables tethering between activated platelets and polymorphonuclear leukocytes via CD11b/CD18

Hamad, Osama A.; Mitroulis, Ioannis; Fromell, Karin; Kozarcanin, Huda et al.

Part of Molecular Immunology, p. 141-142, 2015

Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma

Engberg, Anna E.; Nilsson, Per H.; Huang, Shan; Fromell, Karin et al.

Part of Biomaterials, p. 55-65, 2015

• DOI for Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma

Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Aeinehband, Shahin; Lindblom, Rickard P F; Al Nimer, Faiez; Vijayaraghavan, Swetha et al.

Part of PLOS ONE, 2015

• DOI for Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis
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Low affinity binding of plasma proteins to lipid-coated quantum dots as observed by in situ fluorescence correlation spectroscopy

Klapper, Yvonne; Maffre, Pauline; Shang, Li; Nilsson Ekdahl, Kristina et al.

Part of Nanoscale, p. 9980-9984, 2015

• DOI for Low affinity binding of plasma proteins to lipid-coated quantum dots as observed by in situ fluorescence correlation spectroscopy

Validations of assays for the evaluation of C1q in inflammatory diseases and thromboinflammation

Sandholm, Kerstin; Wijkstrom, Elisabeth; Skattum, Lillemor; Nilsson, Bo et al.

Part of Molecular Immunology, p. 176-177, 2015

Low concentrations of citrate reduce complement and granulocyte activation in vitro in human blood

Huang, Shan; Sandholm, Kerstin; Jonsson, Nina; Nilsson, Anders et al.

Part of Clinical Kidney Journal, p. 31-37, 2015

• DOI for Low concentrations of citrate reduce complement and granulocyte activation in vitro in human blood

Complement activation in asymptomatic Lyme borreliosis and neuroborreliosis

Carlsson, Hanna; Sandholm, Kerstin; Tjernberg, Ivar; Ekdahl, Kristina Nilsson

Part of Molecular Immunology, p. 128-128, 2015

The lectin complement pathway serine proteases bridges the complement and the coagulation systems in thrombotic diseases

Kozarcanin, Huda; Lood, Christian; Munthe-Fog, Lea; Sandholm, Kerstin et al.

Part of Molecular Immunology, p. 153-153, 2015

TiO2 nanoparticles tested in a novel screening whole human blood model of toxicity trigger adverse activation of the kallikrein system at low concentrations

Ekstrand-Hammarstrom, Barbro; Hong, Jaan; Davoodpour, Padideh; Sandholm, Kerstin et al.

Part of Biomaterials, p. 58-68, 2015

• DOI for TiO2 nanoparticles tested in a novel screening whole human blood model of toxicity trigger adverse activation of the kallikrein system at low concentrations

iC3 generation elicited by the presence of ammonia and urea in human plasma

Huang, Shan; Sandholm, Kerstin; Nilsson, Bo; Ekdahl, Kristina Nilsson

Part of Molecular Immunology, p. 145-145, 2015

Rare loss-of-function mutation in C3 provides insight into molecular and pathophysiological determinants of alternative pathway activity

Ricklin, Daniel; Sfyroera, Georgia; Reis, Edimara; Chen, Hui et al.

Part of Molecular Immunology, p. 174-174, 2015

Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy

Teramura, Yuji; Asif, Sana; Nilsson Ekdahl, Kristina; Nilsson, Bo

Part of Advances in Experimental Medicine and Biology, p. 189-209, 2015

• DOI for Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy

Preface: Special Issue 15th European Meeting on Complement in Human Disease 2015, Uppsala, Sweden

Nilsson, Bo; Ekdahl, Kristina Nilsson; Kemper, Claudia; Mollnes, Tom Eirik

Part of Molecular Immunology, p. 1-2, 2015

• DOI for Preface: Special Issue 15th European Meeting on Complement in Human Disease 2015, Uppsala, Sweden

Rare Loss-of-Function Mutation in Complement Component C3 Provides Insight into Molecular and Pathophysiological Determinants of Complement Activity

Sfyroera, Georgia; Ricklin, Daniel; Reis, Edimara S.; Chen, Hui et al.

Part of Journal of Immunology, p. 3305-3316, 2015

• DOI for Rare Loss-of-Function Mutation in Complement Component C3 Provides Insight into Molecular and Pathophysiological Determinants of Complement Activity

Complement factor involvement during experimental AMD

Mohlin, Camilla; Johansson, Kjell; Ekdahl, Kristina Nilsson

Part of Molecular Immunology, p. 163-163, 2015

Liposomal formulations of mistletoe produced by centrifugal technologies suitable for cancer therapy

Leneweit, Gero; Klapper, Yvonne; de Matos, Maria; Hilde-brandt, Ellen et al.

Part of Phytomedicine, 2015

• DOI for Liposomal formulations of mistletoe produced by centrifugal technologies suitable for cancer therapy

Influence of persistent organic pollutants on the complement system in a population-based human sample

Kumar, Jitender; Lind, P. Monica; Salihovic, Samira; van Bavel, Bert et al.

Part of Environment International, p. 94-100, 2014

• DOI for Influence of persistent organic pollutants on the complement system in a population-based human sample

The lectin complement pathway serine proteases (MASPs) represent the crossroad between activation of the coagulation and complement systems

Nilsson, Bo; Kozarcanin, Huda; Lood, Christian; Munthe-Fog, Lea et al.

Part of Molecular Immunology, p. 218-219, 2014

Early Cytokine Release in Response to Live Borrelia burgdorferi Sensu Lato Spirochetes Is Largely Complement Independent

Sandholm, Kerstin; Henningsson, Anna J.; Save, Susanne; Bergstrom, Sven et al.

Part of PLOS ONE, 2014

• DOI for Early Cytokine Release in Response to Live Borrelia burgdorferi Sensu Lato Spirochetes Is Largely Complement Independent
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Mediation of a non-proteolytic activation of complement component C3 by phospholipid vesicles

Klapper, Yvonne; Hamad, Osama A.; Teramura, Yuji; Leneweit, Gero et al.

Part of Biomaterials, p. 3688-3696, 2014

• DOI for Mediation of a non-proteolytic activation of complement component C3 by phospholipid vesicles

C3 And C4 Are Strongly Related To Adipose Tissue Variables And Cardiovascular Risk Factors

Nilsson, Bo; Hamad, Osama A; Ahlström, Håkan; Kullberg, Joel et al.

Part of European Journal of Clinical Investigation, p. 587-596, 2014

• DOI for C3 And C4 Are Strongly Related To Adipose Tissue Variables And Cardiovascular Risk Factors

Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?

Moll, Guido; Alm, Jessica J.; Davies, Lindsay C.; von Bahr, Lena et al.

Part of Stem Cells, p. 2430-2442, 2014

• DOI for Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?

Contact activation of C3 enables tethering between activated platelets and polymorphonuclear leukocytes via CD11b/CD18

Ekdahl, Kristina N.; Hamad, Osama A.; Mitroulis, Ioannis; Fromell, Karin et al.

Part of Molecular Immunology, p. 242-243, 2014

Contact activation products are new potential biomarkers to evaluate the risk of thrombotic events in systemic lupus erythematosus

Bäck, Jennie; Lood, Christian; Bengtsson, Anders A.; Ekdahl, Kristina Nilsson et al.

Part of Arthritis Research & Therapy, 2013

• DOI for Contact activation products are new potential biomarkers to evaluate the risk of thrombotic events in systemic lupus erythematosus
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Regulated Extracellular Choline Acetyltransferase Activity- The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

Vijayaraghavan, Swetha; Karami, Azadeh; Aeinehband, Shahin; Behbahani, Homira et al.

Part of PLOS ONE, 2013

• DOI for Regulated Extracellular Choline Acetyltransferase Activity- The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway
• Download full text (pdf) of Regulated Extracellular Choline Acetyltransferase Activity- The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

C3 convertase antibodies in membranoproliferative glomerulonephritis

Lindner, S.; Chen, Q.; Kirschfink, M.; Nilsson, Bo et al.

Part of Molecular Immunology, p. 286-286, 2013

• DOI for C3 convertase antibodies in membranoproliferative glomerulonephritis

MBL1 genotypes in wild boar populations from Sweden, Austria, the Czech Republic, and Japan

Bergman, I. -M; Sandholm, K.; Ekdahl, Kristina Nilsson; Okumura, N. et al.

Part of INT J IMMUNOGENET, p. 131-139, 2013

• DOI for MBL1 genotypes in wild boar populations from Sweden, Austria, the Czech Republic, and Japan

Evaluation of the blood compatibility of materials, cells and tissues: Basic concepts, test models and practical guidelines

Nilsson Ekdahl, Kristina; Hong, Jaan; Hamad, Osama; Larsson, Rolf et al.

Part of Advances in Experimental Medicine and Biology, p. 257-270, 2013

• DOI for Evaluation of the blood compatibility of materials, cells and tissues: Basic concepts, test models and practical guidelines

Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Karlsson, S. C. Hannah; Lindqvist, A. C.; Fransson, Moa; Paul-Wetterberg, Gabriella et al.

Part of Cancer Gene Therapy, p. 386-393, 2013

• DOI for Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Plasma concentrations of C3 and C4 are linked to cardiovascular risk factors and to the metabolic syndrome

Nilsson, Bo; Ekdahl, Kristina Nilsson; Lind, Lars

Part of Molecular Immunology, p. 252-252, 2013

• DOI for Plasma concentrations of C3 and C4 are linked to cardiovascular risk factors and to the metabolic syndrome

Functional variability in butyrylcholinesterase activity regulates intrathecal cytokine and astroglial biomarker profiles in patients with Alzheimer's disease

Darreh-Shori, Taher; Vijayaraghavan, Swetha; Aeinehband, Shahin; Piehl, Fredrik et al.

Part of Neurobiology of Aging, p. 2465-2481, 2013

• DOI for Functional variability in butyrylcholinesterase activity regulates intrathecal cytokine and astroglial biomarker profiles in patients with Alzheimer's disease

A high blood level in the venous chamber and a wet-stored dialyzer help to reduce exposure for microemboli during hemodialysis

Forsberg, Ulf; Jonsson, Per; Stegmayr, Christofer; Jonsson, Fredrik et al.

Part of Hemodialysis International, p. 612-617, 2013

• DOI for A high blood level in the venous chamber and a wet-stored dialyzer help to reduce exposure for microemboli during hemodialysis

Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating

Nilsson, Per H.; N. Ekdahl, Kristina; Magnusson, Peetra U.; Qu, Hongchang et al.

Part of Biomaterials, p. 985-994, 2013

• DOI for Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating
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Regulation of complement in whole blood by heparin molecularly imprinted polymer particles

Huang, Shan; Nilsson, Per H.; Sandholm, Kerstin; Elmlund, Louise et al.

Part of Immunobiology, p. 1199-1199, 2012

• DOI for Regulation of complement in whole blood by heparin molecularly imprinted polymer particles

Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?

Moll, Guido; Rasmusson-Duprez, Ida; von Bahr, Lena; Connolly-Andersen, Anne-Marie et al.

Part of Stem Cells, p. 1565-1574, 2012

• DOI for Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?

Biomarkers of coagulation, inflammation and angiogenesis are independently associated with preeclampsia

Boij, R.; Berg, G.; Ernerudh, J.; Nilsson-Ekdahl, Kristina et al.

Part of Journal of Reproductive Immunology, p. 109-109, 2012

• DOI for Biomarkers of coagulation, inflammation and angiogenesis are independently associated with preeclampsia

The lectin pathway triggered by activated platelets

Kozarcanin, Huda; Ekdahl, Kristina Nilsson; Nilsson, Bo

Part of Immunobiology, p. 1130-1130, 2012

• DOI for The lectin pathway triggered by activated platelets

A Novel C3 Mutation Causing Increased Formation of the C3 Convertase in Familial Atypical Hemolytic Uremic Syndrome

Sartz, Lisa; Olin, Anders I.; Kristoffersson, Ann-Charlotte; Stahl, Anne-lie et al.

Part of Journal of Immunology, p. 2030-2037, 2012

• DOI for A Novel C3 Mutation Causing Increased Formation of the C3 Convertase in Familial Atypical Hemolytic Uremic Syndrome

Biomarkers of Coagulation, Inflammation, and Angiogenesis are Independently Associated with Preeclampsia

Boij, Roland; Svensson, Judit; Nilsson-Ekdahl, Kristina; Sandholm, Kerstin et al.

Part of American Journal of Reproductive Immunology and Microbiology, p. 258-270, 2012

• DOI for Biomarkers of Coagulation, Inflammation, and Angiogenesis are Independently Associated with Preeclampsia

Investigation of complement activation by neutral liposomes

Klapper, Yvonne; Hamad, Osama; Teramura, Yuji; Leneweit, Gero et al.

Part of Immunobiology, p. 1179-1180, 2012

• DOI for Investigation of complement activation by neutral liposomes

Desensitization With Antigen-Specific Immunoadsorption Interferes With Complement in ABO-Incompatible Kidney Transplantation

Biglarnia, Ali-Reza; Nilsson, Bo; Nilsson Ekdahl, Kristina; Tufveson, Gunnar et al.

Part of Transplantation, p. 87-92, 2012

• DOI for Desensitization With Antigen-Specific Immunoadsorption Interferes With Complement in ABO-Incompatible Kidney Transplantation

Extensive polymorphism in the porcine Toll-like receptor 10 gene

Bergman, I. -M; Edman, K.; Nilsson Ekdahl, Kristina; Rosengren, K. J. et al.

Part of International Journal of Immunogenetics, p. 68-76, 2012

• DOI for Extensive polymorphism in the porcine Toll-like receptor 10 gene

Complement activation products in liquid stored plasma and C3a-kinetics after transfusion of autologous plasma

Norda, Rut; Schött, Ulf; Berseus, Olof; Åkerblom, Olof et al.

Part of Vox Sanguinis, p. 125-133, 2012

• DOI for Complement activation products in liquid stored plasma and C3a-kinetics after transfusion of autologous plasma

Complement activation and phagocytosis in vitro of two strains of Borrelia burgdorferi S.L

Sandholm, Kerstin; Henningsson, Anna J.; Bergstrom, Sven; Ernerudh, Jan et al.

Part of Immunobiology, p. 1153-1153, 2012

• DOI for Complement activation and phagocytosis in vitro of two strains of Borrelia burgdorferi S.L

The ratio between C4 and C4BP adsorbed from plasma predicts cytokine generation induced by artificial polymers in contact with whole blood

Engberg, Anna E.; Nilsson, Per H.; Mollnes, Tom Eirik; Rosengren-Holmberg, Jenny P. et al.

Part of Immunobiology, p. 1211-1211, 2012

• DOI for The ratio between C4 and C4BP adsorbed from plasma predicts cytokine generation induced by artificial polymers in contact with whole blood

Protection of nonself surfaces from complement attack by factor H-binding peptides: Implications for Therapeutic Medicine

Wu, You-Qiang; Qu, Hongchang; Sfyroera, Georgia; Tzekou, Apostolia et al.

Part of Journal of Immunology, p. 4269-4277, 2011

• DOI for Protection of nonself surfaces from complement attack by factor H-binding peptides: Implications for Therapeutic Medicine

Two conformational forms of target-bound iC3b that distinctively bind complement receptors 1 and 2 and two specific monoclonal antibodies

Nilsson, Ulf R.; Funke, Lillemor; Nilsson, Bo; Nilsson Ekdahl, Kristina

Part of Upsala Journal of Medical Sciences, p. 26-33, 2011

• DOI for Two conformational forms of target-bound iC3b that distinctively bind complement receptors 1 and 2 and two specific monoclonal antibodies

Blood protein-polymer adsorption: Implications for understanding complement-mediated hemoincompatibility

Engberg, Anna E.; Rosengren-Holmberg, Jenny P.; Chen, Hui; Nilsson, Bo et al.

Part of Journal of Biomedical Materials Research - Part A, p. 74-84, 2011

• DOI for Blood protein-polymer adsorption: Implications for understanding complement-mediated hemoincompatibility

Mesenchymal Stromal Cells Engage Complement and Complement Receptor Bearing Innate Effector Cells to Modulate Immune Responses

Moll, Guido; Jitschin, Regina; von Bahr, Lena; Duprez, Ida Rasmusson et al.

Part of PLOS ONE, 2011

• DOI for Mesenchymal Stromal Cells Engage Complement and Complement Receptor Bearing Innate Effector Cells to Modulate Immune Responses

Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment

Nilsson, Bo; Nilsson Ekdahl, Kristina; Korsgren, Olle

Part of Current Opinion in Organ Transplantation, p. 620-626, 2011

• DOI for Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment

Identification of complement C3 as an autoantigen in inflammatory bowel disease

Ardesjö Lundgren, Brita; Rorsman, Fredrik; Portela-Gomes, Guida M.; Grimelius, Lars et al.

Part of European Journal of Gastroenterology and Hepathology, p. 429-436, 2010

• DOI for Identification of complement C3 as an autoantigen in inflammatory bowel disease

Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1

Hamad, Osama A.; Nilsson, Per H.; Wouters, Diana; Lambris, John D. et al.

Part of Journal of Immunology, p. 2686-2692, 2010

• DOI for Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1

Mapping pro- and antiangiogenic factors on the surface of prostasomes of normal and malignant cell origin

Babiker, Adil A.; Magnusson, Peetra U.; Ronquist, Gunnar; Nilsson, Bo et al.

Part of The Prostate, p. 834-847, 2010

• DOI for Mapping pro- and antiangiogenic factors on the surface of prostasomes of normal and malignant cell origin

The creation of an antithrombotic surface by apyrase immobilization

Nilsson, Per H.; Engberg, Anna E.; Bäck, Jennie; Faxälv, Lars et al.

Part of Biomaterials, p. 4484-4491, 2010

• DOI for The creation of an antithrombotic surface by apyrase immobilization

Activated human platelets induce factor XIIa-mediated contact activation

Bäck, Jennie; Sanchez, Javier; Elgue, Graciela; Ekdahl, Kristina Nilsson et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 11-17, 2010

• DOI for Activated human platelets induce factor XIIa-mediated contact activation

Hirudin versus heparin for use in whole blood in vitro biocompatibility models

Bexborn, Fredrik; Engberg, Anna E.; Sandholm, Kerstin; Mollnes, Tom Eirik et al.

Part of Journal of Biomedical Materials Research. Part A, p. 951-959, 2009

• DOI for Hirudin versus heparin for use in whole blood in vitro biocompatibility models

Distinctive regulation of contact activation by antithrombin and C1-inhibitor on activated platelets and material surfaces

Bäck, Jennie; Lang, Markus Huber; Elgue, Graciela; Kalbitz, Miriam et al.

Part of Biomaterials, p. 6573-6580, 2009

• DOI for Distinctive regulation of contact activation by antithrombin and C1-inhibitor on activated platelets and material surfaces

Inhibition of complement activation on a model biomaterial surface by streptococcal M protein-derived peptides

Engberg, Anna E.; Sandholm, Kerstin; Bexborn, Fredrik; Persson, Jenny et al.

Part of Biomaterials, p. 2653-2659, 2009

• DOI for Inhibition of complement activation on a model biomaterial surface by streptococcal M protein-derived peptides

Complement Activation by CpG in a Human Whole Blood Loop System: Mechanisms and Immunomodulatory Effects

Mangsbo, Sara M; Sanchez, Javier; Anger, Kerstin; Lambris, John D et al.

Part of Journal of Immunology, p. 6724-6732, 2009

• DOI for Complement Activation by CpG in a Human Whole Blood Loop System: Mechanisms and Immunomodulatory Effects

Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation

Tjernberg, Jenny; Ekdahl, Kristina N.; Lambris, John D.; Korsgren, Olle et al.

Part of Transplantation, p. 1193-1199, 2008

• DOI for Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation

Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation

Goto, Masafumi; Tjernberg, Jenny; Dufrane, Denis; Elgue, Graciela et al.

Part of Xenotransplantation, p. 225-234, 2008

• DOI for Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation

Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets

Hamad, Osama A.; Ekdahl, Kristina Nilsson; Nilsson, P. H.; Andersson, J. et al.

Part of Journal of Thrombosis and Haemostasis, p. 1413-1421, 2008

• DOI for Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets

The tick-over theory revisited: formation and regulation of the soluble alternative complement C3 convertase (C3(H2O)Bb)

Bexborn, Fredrik; Andersson, Per Ola; Chen, Hui; Nilsson, Bo et al.

Part of Molecular Immunology, p. 2370-2379, 2008

• DOI for The tick-over theory revisited: formation and regulation of the soluble alternative complement C3 convertase (C3(H2O)Bb)

Prothrombotic effect of prostasomes of metastatic cell and seminal origin

Babiker, Adil A.; Hamad, Osama A.; Sanchez, Javier; Ronquist, Gunnar et al.

Part of The Prostate, p. 378-388, 2007

• DOI for Prothrombotic effect of prostasomes of metastatic cell and seminal origin

Complement activation in Lyme neuroborreliosis: increased levels of C1q and C3a in cerebrospinal fluid indicate complement activation in the CNS

Henningsson, Anna J.; Ernerudh, Jan; Sandholm, Kerstin; Carlsson, Sten-Anders et al.

Part of Journal of Neuroimmunology, p. 200-207, 2007

• DOI for Complement activation in Lyme neuroborreliosis: increased levels of C1q and C3a in cerebrospinal fluid indicate complement activation in the CNS

Use of serum or buffer-changed EDTA-plasma in a rapid, inexpensive, and easy-to-perform hemolytic complement assay for differential diagnosis of systemic lupus erythematosus and monitoring of patients with the disease

Ekdahl, Kristina N.; Norberg, Dan; Bengtsson, Anders A.; Sturfelt, Gunnar et al.

Part of Clinical and Vaccine Immunology, p. 549-555, 2007

• DOI for Use of serum or buffer-changed EDTA-plasma in a rapid, inexpensive, and easy-to-perform hemolytic complement assay for differential diagnosis of systemic lupus erythematosus and monitoring of patients with the disease

The role of complement in biomaterial-induced inflammation

Nilsson, Bo; Ekdahl, Kristina Nilsson; Mollnes, Tom Eirik; Lambris, John D.

Part of Molecular Immunology, p. 82-94, 2007

• DOI for The role of complement in biomaterial-induced inflammation

Surface-attached PEO in the form of activated Pluronic with immobilized factor H reduces both coagulation and complement activation in a whole-blood model.

Andersson, Jonas; Bexborn, Fredrik; Klinth, Jeanna; Nilsson, Bo et al.

Part of J Biomed Mater Res A, p. 25-34, 2006

Overexpression of ecto-protein kinases in prostasomes of metastatic cell origin

Babiker, Adil A.; Ronquist, Gunnar; Nilsson, Bo; Nilsson Ekdahl, Kristina

Part of The Prostate, p. 675-686, 2006

• DOI for Overexpression of ecto-protein kinases in prostasomes of metastatic cell origin

Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome in clinical islet transplantation

Johansson, Helena; Lukinius, Agneta; Moberg, Lisa; Lundgren, Torbjörn et al.

Part of Diabetes, p. 1755-62, 2005

• DOI for Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome in clinical islet transplantation

Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation

Johansson, Helena; Lukinius, Agneta; Moberg, Lisa; Lundgren, Torbjörn et al.

Part of Diabetes, p. 1755-62, 2005

• DOI for Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation

Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface.

Andersson, Jonas; Ekdahl, Kristina Nilsson; Lambris, John D; Nilsson, Bo

Part of Biomaterials, p. 1477-85, 2005

Transfer of functional prostasomal CD59 of metastatic prostatic cancer cell origin protects cells against complement attck

Babiker, Adil A.; Nilsson, Bo; Ronquist, Gunnar; Carlsson, Lena et al.

Part of The Prostate, p. 105-114, 2005

• DOI for Transfer of functional prostasomal CD59 of metastatic prostatic cancer cell origin protects cells against complement attck

Material-specific thrombin generation following contact between metal surfaces and whole blood.

Hong, Jaan; Azens, Andris; Nilsson Ekdahl, Kristina; Granqvist, Claes Göran et al.

Part of Biomaterials, p. 1397-403, 2005

Immune complex-stimulated production of interleukin-12 in peripheral blood

Tejde, Andreas; Mathsson, Linda; Nilsson Ekdahl, Kristina; Nilsson, Bo et al.

Part of Clin Exp Immunol, p. 521-8, 2004

Thrombotic disease in systemic lupus erythematosus is associated with a maintained systemic platelet activation.

Nilsson Ekdahl, Kristina; Bengtsson, Anders A; Andersson, Jonas; Elgue, Graciela et al.

Part of Br J Haematol, p. 74, 2004

Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation

Moberg, Lisa; Johansson, Helena; Lukinius, Agneta; Berne, Christian et al.

Part of The Lancet, p. 2039-45, 2002

• DOI for Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation

Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation.

Moberg, Lisa; Ekdahl, Kristina Nilsson; Elgue, Graciela; Larsson, Rolf et al.

Part of Diabetes, p. 1779-84, 2002

C3 adsorbed to a polymer surface can form an initiating alternative pathway convertase.

Andersson, Jonas; Nilsson Ekdahl, Kristina; Larsson, Rolf; Nilsson, Ulf R et al.

Part of J Immunol, p. 5786, 2002

Contact between a polymer and whole blood: sequence of events leading to thrombin generation.

Hong, Jaan; Larsson, Anders; Ekdahl, Kristina; Elgue, Graciela et al.

Part of J Lab Clin Med, p. 139, 2001

C-Peptide determinations in islet xenotransplantation: A study in the pig-to-mouse model.

Wennberg, L; Sundberg, B; Nilsson Ekdahl, Kristina; Korsgren, Olle

Part of Cell Transplant., p. 165, 2001

Binding of a model regulator of complement activation (RCA) to a biomaterial surface: surface-bound factor H inhibits complement activation.

Andersson, Jonas; Larsson, Rolf; Richter, Ralf; Nilsson Ekdahl, Kristina et al.

Part of Biomaterials, p. 2435, 2001

Complement C3b interactions studied with surface plasmon resonance technique

Jokiranta, T S; Westin, Jerker; Nilsson, Ulf R; Nilsson, Bo et al.

Part of International Immunopharmacology, p. 495-506, 2001

• DOI for Complement C3b interactions studied with surface plasmon resonance technique

Opsonization of yeast cells with equine iC3b, C3b, and IgG

Gröndahl, Gittan; Johannisson, Anders; Jensen-Waern, Marianne; Nilsson Ekdahl, Kristina

Part of Veterinary Immunology and Immunopathology, p. 1-15, 2001

Phosphorylation of C3 by a casein kinase released from activated human platelets increases opsonization of immune complexes and binding to complement receptor type 1.

Nilsson Ekdahl, Kristina; Nilsson, Bo

Part of Eur J Immunol, p. 1047-54, 2001

Correlation between anti-C1q and immune conglutinin levels, but not between levels of antibodies to the structurally related autoantigens C1q and collagen type II in SLE or RA.

Rönnelid, Johan; Gunnarsson, I; Nilsson Ekdahl, K; Nilsson, B

Part of J Autoimunity, p. 415, 1997

Therapeutic regulation of complement activation in extracorporeal circuits and intravascular treatments with special reference to the alternative pathway amplification loop

Ekdahl, Kristina N.; Fromell, Karin; Mannes, Marco; Grinnemo, Karl-Henrik et al.

Part of Immunological Reviews, p. 91-103, 2023

• DOI for Therapeutic regulation of complement activation in extracorporeal circuits and intravascular treatments with special reference to the alternative pathway amplification loop
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How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment

Nilsson, Bo; Persson, Barbro; Eriksson, Oskar; Fromell, Karin et al.

Part of Frontiers in Immunology, 2022

• DOI for How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment
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Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde

Mannes, Marco; Mastellos, Dimitrios C.; Ekdahl, Kristina N.; Nilsson, Bo et al.

Part of Seminars in Immunology, 2022

• DOI for Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde

Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis

Mannes, Marco; Schmidt, Christoph Q.; Nilsson, Bo; Nilsson Ekdahl, Kristina et al.

Part of Seminars in Immunopathology, p. 773-788, 2021

• DOI for Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis
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The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System

Eriksson, Oskar; Mohlin, Camilla; Nilsson, Bo; N. Ekdahl, Kristina

Part of Frontiers in Immunology, 2019

• DOI for The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System
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Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics

Mohebnasab, Maedeh; Eriksson, Oskar; Persson, Barbro; Sandholm, Kerstin et al.

Part of Frontiers in Immunology, 2019

• DOI for Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics
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A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity

N.Ekdahl, Kristina; Fromell, Karin; Mohlin, Camilla; Teramura, Yuji et al.

Part of Science and Technology of Advanced Materials, p. 688-698, 2019

• DOI for A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity
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The multifaceted role of complement in kidney transplantation

Biglarnia, Ali-Reza; Huber-Lang, Markus; Mohlin, Camilla; Nilsson Ekdahl, Kristina et al.

Part of Nature Reviews Nephrology, p. 767-781, 2018

• DOI for The multifaceted role of complement in kidney transplantation

Interpretation of Serological Complement Biomarkers in Disease

Nilsson Ekdahl, Kristina; Persson, Barbro; Mohlin, Camilla; Sandholm, Kerstin et al.

Part of Frontiers in Immunology, 2018

• DOI for Interpretation of Serological Complement Biomarkers in Disease
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Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions

Huber-Lang, Markus; Nilsson Ekdahl, Kristina; Wiegner, Rebecca; Fromell, Karin et al.

Part of Seminars in Immunopathology, p. 87-102, 2018

• DOI for Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions
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Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

Ekdahl, Kristina N; Soveri, Inga; Hilborn, Jöns; Fellström, Bengt et al.

Part of Nature Reviews Nephrology, p. 285-296, 2017

• DOI for Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

A hybrid of cells and pancreatic islets toward a new bioartificial pancreas

Teramura, Yuji; Nilsson Ekdahl, Kristina; Barbu, Andreea R

Part of Regenerative Therapy, p. 68-74, 2016

• DOI for A hybrid of cells and pancreatic islets toward a new bioartificial pancreas
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The role of complement factor C3 in lipid metabolism

Barbu, Andreea; Hamad, Osama A.; Lind, Lars; Ekdahl, Kristina Nilsson et al.

Part of Molecular Immunology, p. 101-107, 2015

• DOI for The role of complement factor C3 in lipid metabolism

Complement and platelets: Mutual interference in the immune network

Speth, Cornelia; Rambach, Guenter; Wuerzner, Reinhard; Lass-Floerl, Cornelia et al.

Part of Molecular Immunology, p. 108-118, 2015

• DOI for Complement and platelets: Mutual interference in the immune network

Thromboinflammation in Therapeutic Medicine

Nilsson Ekdahl, Kristina; Teramura, Yuji; Asif, Sana; Jonsson, Nina et al.

Part of Advances in Experimental Medicine and Biology, p. 3-17, 2015

• DOI for Thromboinflammation in Therapeutic Medicine

The role and regulation of complement activation as part of the thromboinflammation elicited in cell therapies

Nilsson, Bo; Teramura, Yuji; Ekdahl, Kristina N.

Part of Molecular Immunology, p. 185-190, 2014

• DOI for The role and regulation of complement activation as part of the thromboinflammation elicited in cell therapies

The tick-over theory revisited: Is C3 a contact-activated protein?

Nilsson, Bo; Ekdahl, Kristina Nilsson

Part of Immunobiology, p. 1106-1110, 2012

• DOI for The tick-over theory revisited: Is C3 a contact-activated protein?

Complement Diagnostics: Concepts, Indications, and Practical Guidelines

Nilsson, Bo; Ekdahl, Kristina Nilsson

Part of Clinical & Developmental Immunology, p. 962702, 2012

• DOI for Complement Diagnostics: Concepts, Indications, and Practical Guidelines

Innate immunity activation on biomaterial surfaces: a mechanistic model and coping strategie

Nilsson Ekdahl, Kristina; Lambris, John; Elwing, Hans; Ricklin, Daniel et al.

Part of Advanced Drug Delivery Reviews, p. 1042-1050, 2011

• DOI for Innate immunity activation on biomaterial surfaces: a mechanistic model and coping strategie

Prostasome Involvement in the Development and Growth of Prostate Cancer

Babiker, Adil A.; Ronquist, Gunnar; Nilsson, Bo; Nilsson Ekdahl, Kristina

Part of The Open Prostate Cancer Journal, p. 1-13, 2010

• DOI for Prostasome Involvement in the Development and Growth of Prostate Cancer
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Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?

Nilsson, Bo; Korsgren, Olle; Lambris, John D.; Ekdahl, Kristina Nilsson

Part of Trends in immunology, p. 32-38, 2010

• DOI for Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?

Prothrombotic effects of prostasomes isolated from prostatic cancer cell lines and seminal plasma

Babiker, Adil A.; Ekdahl, Kristina Nilsson; Nilsson, Bo; Ronquist, Gunnar

Part of Seminars in Thrombosis and Hemostasis, p. 80-86, 2007

• DOI for Prothrombotic effects of prostasomes isolated from prostatic cancer cell lines and seminal plasma

Complement and coagulation: strangers or partners in crime?

Markiewski, Maciej M.; Nilsson, Bo; Ekdahl, Kristina Nilsson; Mollnes, Tom Eirik et al.

Part of Trends in immunology, p. 184-192, 2007

• DOI for Complement and coagulation: strangers or partners in crime?

Immune complexes from SLE sera induce IL10 productionfrom normal peripheral blood mononuclear cells by anFcvicious cycle maintaining B cell hyperactivity in SLEgRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLE

Rönnelid, Johan; Tejde, Andreas; Mathsson, Linda; Nilsson Ekdahl, Kristina et al.

Part of Annals of the Rheumatic Diseases, p. 37-42, 2003

• DOI for Immune complexes from SLE sera induce IL10 productionfrom normal peripheral blood mononuclear cells by anFcvicious cycle maintaining B cell hyperactivity in SLEgRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLE

Quantification of Complement Proteins with Special Reference to C1q: Multiplex Versus ELISA Versus Rocket Immunoelectrophoresis Versus Nephelometry

Sandholm, Kerstin; Persson, Barbro; Abdalla, Sliva; Mohlin, Camilla et al.

Part of The Complement System, p. 33-41, Humana Press, 2021

• DOI for Quantification of Complement Proteins with Special Reference to C1q: Multiplex Versus ELISA Versus Rocket Immunoelectrophoresis Versus Nephelometry

The innate immunity response: A key factor in biocompatibility

Ekdahl, Kristina N; Fromell, Karin; Hilborn, Jöns; Nilsson, Bo

Part of Bioresorbable Polymers for Biomedical Applications, p. 85-94, Elsevier, 2017

Complement Proteins In Long-Term Weight Responders And Non-Responders After Gastric Bypass

Sima, Eduardo; Nilsson, Berith; Nilsson Ekdahl, Kristina; Sundbom, Magnus

Part of IFSO 2017 22^nd World Congress, p. 679-679, 2017

Complement Interception Across Humoral Incompatibility in Solid Organ Transplantation: A Clinical Perspective

Biglarnia, Ali-Reza; Nilsson, Kristina Ekdahl; Nilsson, Bo

Part of IMMUNE RESPONSES TO BIOSURFACES, p. 211-233, 2015

• DOI for Complement Interception Across Humoral Incompatibility in Solid Organ Transplantation: A Clinical Perspective

Preface

Lambris, John D.; Ekdahl, Kristina N.; Ricklin, Daniel; Nilsson, Bo

Part of IMMUNE RESPONSES TO BIOSURFACES, 2015

Platelets, complement, and contact activation: partners in inflammation and thrombosis

Hamad, Osama A; Bäck, Jennie; Nilsson, Per H; Nilsson, Bo et al.

Part of Current Topics In Innate Immunity II, p. 185-205, 2012

• DOI for Platelets, complement, and contact activation: partners in inflammation and thrombosis

Immunity in borreliosis with special emphasis on the role of complement

Ekdahl, Kristina Nilsson; Henningsson, Anna Jonsson; Sandholm, Kerstin; Forsberg, Pia et al.

Part of CURRENT TOPICS IN INNATE IMMUNITY, p. 198-213, 2007

Validation of an MPC polymer coating to reduce surface-induced cascade system activation in whole blood in in vitroand in vivo models

Asif, Sana; Asawa, Kenta; Yuuki, Inoue; Kazuhiko, Ishihara2 et al.

Activation of the kallikrein-kinin system is associated with deteriorated oxygen saturation and thrombotic events in SARS-CoV-2 infection.

Persson, Barbro; Zetterberg, Eva; Eriksson, Anna; Eikrem, David et al.