Gaetano Perchiazzi
Adjunct senior lecturer Associate Professor at Department of Surgical Sciences; Anaesthesiology and Intensive Care
- Mobile phone:
- +46 70 564 08 61
- E-mail:
- gaetano.perchiazzi@uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 70, 1tr
751 85 Uppsala - Postal address:
- Akademiska sjukhuset, ingång 70, 1tr
751 85 UPPSALA
- ORCID:
- 0000-0001-6834-6399
Short presentation
Medical Doctor (consultant), Specialist in Anesthesia and Intensive Care Medicine, PhD in Clinical Physiology. He is Associate Professor and Senior Lecturer in this University. He works clinically in the intensive care units of Akademiska Sjukhuset. His research activities are based at the Hedenstierna Laboratory. He is the coordinator of the doctoral research track on "Lung function, ventilation and airway diseases".
Keywords
- respiratory mechanics
- artificial intelligence
- artificial neural networks
- image analysis
- acute respiratory distress syndrome
- mechanical ventilation
- synchrotron radiation computed tomography
- lung
Research
His research field is artificial ventilation applied to intensive care patients. Together with his team studies respiratory mechanics by using numerical analysis of lung images and methods of artificial intelligence on respiratory tracings. For detailed information about his research field, click here.

Publications
Recent publications
Part of Intensive Care Medicine Experimental, 2025
- DOI for The focal index: a quantitative approach to morphological sub-phenotyping of COVID-19 patients with acute respiratory distress syndrome: a pilot study
- Download full text (pdf) of The focal index: a quantitative approach to morphological sub-phenotyping of COVID-19 patients with acute respiratory distress syndrome: a pilot study
PET imaging of platelet derived growth factor receptor β in lung fibrosis
Part of EJNMMI Radiopharmacy and Chemistry, 2025
- DOI for PET imaging of platelet derived growth factor receptor β in lung fibrosis
- Download full text (pdf) of PET imaging of platelet derived growth factor receptor β in lung fibrosis
Nanoscale structural alteration of lung collagen in response to strain and bleomycin injury
Part of Scientific Reports, 2025
- DOI for Nanoscale structural alteration of lung collagen in response to strain and bleomycin injury
- Download full text (pdf) of Nanoscale structural alteration of lung collagen in response to strain and bleomycin injury
Self-Induced Lung Injury and the Quest for a Smoking Gun: A Nosologic Perspective
Part of Acta Anaesthesiologica Scandinavica, 2025
Part of Intensive Care Medicine Experimental, 2025
- DOI for Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study
- Download full text (pdf) of Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study
All publications
Articles in journal
Part of Intensive Care Medicine Experimental, 2025
- DOI for The focal index: a quantitative approach to morphological sub-phenotyping of COVID-19 patients with acute respiratory distress syndrome: a pilot study
- Download full text (pdf) of The focal index: a quantitative approach to morphological sub-phenotyping of COVID-19 patients with acute respiratory distress syndrome: a pilot study
PET imaging of platelet derived growth factor receptor β in lung fibrosis
Part of EJNMMI Radiopharmacy and Chemistry, 2025
- DOI for PET imaging of platelet derived growth factor receptor β in lung fibrosis
- Download full text (pdf) of PET imaging of platelet derived growth factor receptor β in lung fibrosis
Nanoscale structural alteration of lung collagen in response to strain and bleomycin injury
Part of Scientific Reports, 2025
- DOI for Nanoscale structural alteration of lung collagen in response to strain and bleomycin injury
- Download full text (pdf) of Nanoscale structural alteration of lung collagen in response to strain and bleomycin injury
Self-Induced Lung Injury and the Quest for a Smoking Gun: A Nosologic Perspective
Part of Acta Anaesthesiologica Scandinavica, 2025
Part of Intensive Care Medicine Experimental, 2025
- DOI for Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study
- Download full text (pdf) of Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study
Part of Journal of clinical monitoring and computing, p. 1269-1280, 2024
- DOI for Imitating the respiratory activity of the brain stem by using artificial neural networks: exploratory study on an animal model of lactic acidosis and proof of concept
- Download full text (pdf) of Imitating the respiratory activity of the brain stem by using artificial neural networks: exploratory study on an animal model of lactic acidosis and proof of concept
Part of Intensive Care Medicine Experimental, 2024
- DOI for Positive end-expiratory pressure limits inspiratory effort through modulation of the effort-to-drive ratio: an experimental crossover study
- Download full text (pdf) of Positive end-expiratory pressure limits inspiratory effort through modulation of the effort-to-drive ratio: an experimental crossover study
Part of Intensive Care Medicine Experimental, 2024
- DOI for Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury: an experimental study
- Download full text (pdf) of Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury: an experimental study
Part of Frontiers in Physiology, 2024
- DOI for Body mass index is associated with pulmonary gas and blood distribution mismatch in COVID-19 acute respiratory failure: A physiological study
- Download full text (pdf) of Body mass index is associated with pulmonary gas and blood distribution mismatch in COVID-19 acute respiratory failure: A physiological study
Water-Based Conductive Ink Formulations for Enzyme-Based Wearable Biosensors
Part of Advanced Sensor Research, 2024
- DOI for Water-Based Conductive Ink Formulations for Enzyme-Based Wearable Biosensors
- Download full text (pdf) of Water-Based Conductive Ink Formulations for Enzyme-Based Wearable Biosensors
Part of Scientific Reports, 2024
- DOI for Quantifying heterogeneity in an animal model of acute respiratory distress syndrome, a comparison of inspired sinewave technique to computed tomography
- Download full text (pdf) of Quantifying heterogeneity in an animal model of acute respiratory distress syndrome, a comparison of inspired sinewave technique to computed tomography
Part of Intensive Care Medicine Experimental, 2023
- DOI for Intra-tidal PaO2 oscillations associated with mechanical ventilation: a pilot study to identify discrete morphologies in a porcine model
- Download full text (pdf) of Intra-tidal PaO2 oscillations associated with mechanical ventilation: a pilot study to identify discrete morphologies in a porcine model
Part of Intensive Care Medicine Experimental, 2023
- DOI for Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis
- Download full text (pdf) of Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis
Part of PLOS ONE, 2023
- DOI for Quantitative assessment of atelectasis formation under high frequency jet ventilation during liver tumour ablation: A computer tomography study
- Download full text (pdf) of Quantitative assessment of atelectasis formation under high frequency jet ventilation during liver tumour ablation: A computer tomography study
PET imaging of neutrophil elastase with 11C-GW457427 in Acute Respiratory Distress Syndrome in pigs
Part of Journal of Nuclear Medicine, p. 423-429, 2023
Lung tissue biomechanics imaged with synchrotron phase contrast microtomography in live rats
Part of Scientific Reports, 2022
- DOI for Lung tissue biomechanics imaged with synchrotron phase contrast microtomography in live rats
- Download full text (pdf) of Lung tissue biomechanics imaged with synchrotron phase contrast microtomography in live rats
Göran Hedenstierna (1941-2021)
Part of Clinical Physiology and Functional Imaging, p. 146-147, 2022
Part of Respiratory Research, 2022
- DOI for Homogenizing effect of PEEP on tidal volume distribution during neurally adjusted ventilatory assist: study of an animal model of acute respiratory distress syndrome
- Download full text (pdf) of Homogenizing effect of PEEP on tidal volume distribution during neurally adjusted ventilatory assist: study of an animal model of acute respiratory distress syndrome
In Memoriam: Göran Hedenstierna (1941-2021)
Part of Acta Anaesthesiologica Scandinavica, p. 165-166, 2022
PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
Part of EJNMMI Research, 2022
- DOI for PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
- Download full text (pdf) of PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
Part of Critical Care, 2022
- DOI for Limitations of the ARDS criteria during high-flow oxygen or non-invasive ventilation: evidence from critically ill COVID-19 patients
- Download full text (pdf) of Limitations of the ARDS criteria during high-flow oxygen or non-invasive ventilation: evidence from critically ill COVID-19 patients
Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients
Part of Critical Care, 2022
- DOI for Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients
- Download full text (pdf) of Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients
Part of American Journal of Veterinary Research, p. 162-170, 2022
Part of Frontiers in Physiology, 2021
- DOI for Inspiratory Efforts, Positive End-Expiratory Pressure, and External Resistances Influence Intraparenchymal Gas Redistribution in Mechanically Ventilated Injured Lungs
- Download full text (pdf) of Inspiratory Efforts, Positive End-Expiratory Pressure, and External Resistances Influence Intraparenchymal Gas Redistribution in Mechanically Ventilated Injured Lungs
Part of Journal of applied physiology, p. 813-826, 2021
Comparison of two injectable anaesthetic techniques on induction and subsequent anaesthesia in pigs
Part of Laboratory Animals, p. 540-550, 2021
Part of Critical Care, 2021
- DOI for A quantitative analysis of extension and distribution of lung injury in COVID-19: a prospective study based on chest computed tomography
- Download full text (pdf) of A quantitative analysis of extension and distribution of lung injury in COVID-19: a prospective study based on chest computed tomography
Part of Acta Anaesthesiologica Scandinavica, p. 211-215, 2020
Expiratory Resistances Prevent Expiratory Diaphragm Contraction, Flow Limitation, and Lung Collapse
Part of American Journal of Respiratory and Critical Care Medicine, p. 1218-1229, 2020
Part of Respiratory Physiology & Neurobiology, 2020
Part of Frontiers in Physiology, 2020
- DOI for Influence of Positive End-Expiratory Pressure Titration on the Effects of Pronation in Acute Respiratory Distress Syndrome: A Comprehensive Experimental Study
- Download full text (pdf) of Influence of Positive End-Expiratory Pressure Titration on the Effects of Pronation in Acute Respiratory Distress Syndrome: A Comprehensive Experimental Study
Part of Best Practice & Research, p. 561-567, 2020
- DOI for The use of positive end expiratory pressure in patients affected by COVID-19: Time to reconsider the relation between morphology and physiology
- Download full text (pdf) of The use of positive end expiratory pressure in patients affected by COVID-19: Time to reconsider the relation between morphology and physiology
Part of Frontiers in Physiology, 2019
- DOI for The Effects of Positive End-Expiratory Pressure on Transpulmonary Pressure and Recruitment-Derecruitment During Neurally Adjusted Ventilator Assist: A Continuous Computed Tomography Study in an Animal Model of Acute Respiratory Distress Syndrome
- Download full text (pdf) of The Effects of Positive End-Expiratory Pressure on Transpulmonary Pressure and Recruitment-Derecruitment During Neurally Adjusted Ventilator Assist: A Continuous Computed Tomography Study in an Animal Model of Acute Respiratory Distress Syndrome
Part of Frontiers in Physiology, 2019
- DOI for Regional Behavior of Airspaces During Positive Pressure Reduction Assessed by Synchrotron Radiation Computed Tomography
- Download full text (pdf) of Regional Behavior of Airspaces During Positive Pressure Reduction Assessed by Synchrotron Radiation Computed Tomography
Does the antisecretory peptide AF-16 reduce lung oedema in experimental ARDS?
Part of Upsala Journal of Medical Sciences, p. 246-253, 2019
- DOI for Does the antisecretory peptide AF-16 reduce lung oedema in experimental ARDS?
- Download full text (pdf) of Does the antisecretory peptide AF-16 reduce lung oedema in experimental ARDS?
Part of Respiratory Research, 2019
- DOI for Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory distress syndrome in adult rabbits
- Download full text (pdf) of Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory distress syndrome in adult rabbits
Acute Respiratory Distress Syndrome (ARDS): Pathophysiological Insights and Lung Imaging
Part of Journal of Clinical Medicine, 2019
- DOI for Acute Respiratory Distress Syndrome (ARDS): Pathophysiological Insights and Lung Imaging
- Download full text (pdf) of Acute Respiratory Distress Syndrome (ARDS): Pathophysiological Insights and Lung Imaging
Expiratory Resistances Prevent Expiratory Diaphragm Contraction, Flow Limitation, and Lung Collapse
Part of Intensive Care Medicine Experimental, 2019
Visualizing Regional Changes Between Lateral, Supine and Prone Position in Pigs with Lung Injury
2019
Individual Airway Closure Characterized In Vivo by Phase-Contrast CT Imaging in Injured Rabbit Lung
Part of Critical Care Medicine, 2019
Part of Anesthesiology, p. 765-768, 2019
2018
Onset and Magnitude of Pendelluft During Spontaneous Breathing Depend on Lung Volume
Part of American Journal of Respiratory and Critical Care Medicine, 2018
Part of American Journal of Respiratory and Critical Care Medicine, 2018
Part of Anesthesiology, p. 222-224, 2018
Part of Acta Anaesthesiologica Scandinavica, p. 820-828, 2018
Part of Acta Anaesthesiologica Scandinavica, p. 94-104, 2018
Part of Critical Care Medicine, p. 687-694, 2017
The Diaphragm Acts as a Brake During Expiration to Prevent Lung Collapse
Part of American Journal of Respiratory and Critical Care Medicine, p. 1608-1616, 2017
Part of Medical and Biological Engineering and Computing, p. 1819-1828, 2017
- DOI for Robustness of two different methods of monitoring respiratory system compliance during mechanical ventilation.
- Download full text (pdf) of Robustness of two different methods of monitoring respiratory system compliance during mechanical ventilation.
Who Can Make Sense of the WHO Guidelines to Prevent Surgical Site Infection?
Part of Anesthesiology, p. 771-773, 2017
Part of American Journal of Respiratory and Critical Care Medicine, 2017
Part of Journal of clinical monitoring and computing, p. 551-559, 2017
Effects of superimposed tissue weight on regional compliance of injured lungs
Part of Respiratory Physiology & Neurobiology, p. 16-24, 2016
Part of American Journal of Respiratory and Critical Care Medicine, 2016
Part of Acta Anaesthesiologica Scandinavica, p. 958-968, 2016
- DOI for Zero expiratory pressure and low oxygen concentration promote heterogeneity of regional ventilation and lung densities
- Download full text (pdf) of Zero expiratory pressure and low oxygen concentration promote heterogeneity of regional ventilation and lung densities
Part of American Journal of Respiratory and Critical Care Medicine, 2015
Regional distribution of lung compliance by image analysis of computed tomograms
Part of Respiratory Physiology & Neurobiology, p. 60-70, 2014
Lung regional stress and strain as a function of posture and ventilatory mode
Part of Journal of applied physiology, p. 1374-1383, 2011
Oleic acid lung injury: a morphometric analysis using computed tomography
Part of Acta Anaesthesiologica Scandinavica, p. 1123-1129, 2004
Part of Anesth Analg, p. 782-9, table of contents, 2004
Articles, review/survey
Part of Frontiers in Physiology, 2022
- DOI for Imaging Regional Lung Structure and Function in Small Animals Using Synchrotron Radiation Phase-Contrast and K-Edge Subtraction Computed Tomography
- Download full text (pdf) of Imaging Regional Lung Structure and Function in Small Animals Using Synchrotron Radiation Phase-Contrast and K-Edge Subtraction Computed Tomography
What is new in respiratory monitoring?
Part of Journal of clinical monitoring and computing, p. 599-607, 2022
Pathophysiology of musculoskeletal pain: a narrative review
Part of Therapeutic Advances in Musculoskeletal Disease, p. 1-12, 2021
- DOI for Pathophysiology of musculoskeletal pain: a narrative review
- Download full text (pdf) of Pathophysiology of musculoskeletal pain: a narrative review
Journal of Clinical Monitoring and Computing 2018-2019 end of year summary: respiration
Part of Journal of clinical monitoring and computing, p. 197-205, 2020
Imaging the Injured Lung: Mechanisms of Action and Clinical Use
Part of Anesthesiology, p. 716-749, 2019
Journal of Clinical Monitoring and Computing 2017 end of year summary: respiration
Part of Journal of clinical monitoring and computing, p. 197-205, 2018
Chapters in book
Part of Intensivvård, p. 278-293, Liber, 2020
Conference papers
Flexible Carbon-based electrodes for amperometric biosensor development
Part of 2024 IEEE International Conference on Flexible and Printable Sensors and Systems, FLEPS, p. 1-4, 2024
Expiratory Diaphragm Activity Reduces Atelectasis Formation
2016
Expiratory Diaphragm Activity Reduces Atelectasis Formation
2016