Jenny Hallgren Martinsson

Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors

Alvarado-Vazquez, Perla Abigail; Méndez-Enriquez, Erika; Salomonsson, Maya; Kopac, Peter et al.

Part of Journal of Allergy and Clinical Immunology, p. 1310-1320, 2025

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A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection

von Beek, Christopher; Fahlgren, Anna; Geiser, Petra; Di Martino, Maria Letizia et al.

Part of Nature Communications, 2024

• DOI for A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
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Lin^-CD117⁺CD34⁺FcεRI⁺ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy

Ridge, Katie; Moran, Barry; Alvarado-Vazquez, P. Abigail; Hallgren, Jenny et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2423-2434, 2024

• DOI for Lin^-CD117⁺CD34⁺FcεRI⁺ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy
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Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)

Valentini, Paolo; Akula, Srinivas; Alvarado-Vazquez, Perla Abigail; Hallgren, Jenny et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)
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Mast cells contribute to T-cell accumulation in the bronchoalveolar space in mice with IL-33-induced airway inflammation

Alvarado-Vazquez, Perla Abigail; Mendez-Enriquez, Erika; Pähn, Lisa; Dondalska, Aleksandra et al.

Part of Immunology, p. 590-602, 2024

• DOI for Mast cells contribute to T-cell accumulation in the bronchoalveolar space in mice with IL-33-induced airway inflammation
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Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors

Alvarado-Vazquez, Perla Abigail; Méndez-Enriquez, Erika; Salomonsson, Maya; Kopac, Peter et al.

Part of Journal of Allergy and Clinical Immunology, p. 1310-1320, 2025

• DOI for Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
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A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection

von Beek, Christopher; Fahlgren, Anna; Geiser, Petra; Di Martino, Maria Letizia et al.

Part of Nature Communications, 2024

• DOI for A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
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Lin^-CD117⁺CD34⁺FcεRI⁺ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy

Ridge, Katie; Moran, Barry; Alvarado-Vazquez, P. Abigail; Hallgren, Jenny et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2423-2434, 2024

• DOI for Lin^-CD117⁺CD34⁺FcεRI⁺ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy
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Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)

Valentini, Paolo; Akula, Srinivas; Alvarado-Vazquez, Perla Abigail; Hallgren, Jenny et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)
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Mast cells contribute to T-cell accumulation in the bronchoalveolar space in mice with IL-33-induced airway inflammation

Alvarado-Vazquez, Perla Abigail; Mendez-Enriquez, Erika; Pähn, Lisa; Dondalska, Aleksandra et al.

Part of Immunology, p. 590-602, 2024

• DOI for Mast cells contribute to T-cell accumulation in the bronchoalveolar space in mice with IL-33-induced airway inflammation
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Characterization of Freshly Isolated Human Peripheral Blood B Cells, Monocytes, CD4⁺ and CD8⁺ T Cells, and Skin Mast Cells by Quantitative Transcriptomics

Akula, Srinivas; Alvarado-Vazquez, Abigail; Mendez Enriquez, Erika Haide; Bal, Gürkan et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Characterization of Freshly Isolated Human Peripheral Blood B Cells, Monocytes, CD4⁺ and CD8⁺ T Cells, and Skin Mast Cells by Quantitative Transcriptomics
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Urticaria and angioedema in Estonia, Iceland and Sweden

Heldin, Johanna; Malinovschi, Andrei; Amid Hägg, Shadi; Gíslason, Thorarinn et al.

Part of Clinical and Experimental Allergy, p. 228-230, 2024

• DOI for Urticaria and angioedema in Estonia, Iceland and Sweden
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Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity

Aybay, Erdem; Ryu, Jinhye; Fu, Zhirong; Akula, Srinivas et al.

Part of Frontiers in Immunology, 2023

• DOI for Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity
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­­Circulating mast cell progenitors increase in frequency during natural birch pollen exposure in allergic asthma patients

Alvarado-Vazquez, Perla Abigail; Mendez-Enriquez, Erika; Salomonsson, Maya; Waern, Ida et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2959-2968, 2023

• DOI for ­­Circulating mast cell progenitors increase in frequency during natural birch pollen exposure in allergic asthma patients
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Tryptase reference values in a Swedish middle-aged general population and association with diabetes mellitus

Vitte, Joana; Sjölander, Anders; Rydell, Niclas; Molin, Magnus et al.

Part of Clinical and Experimental Allergy, p. 1330-1333, 2022

• DOI for Tryptase reference values in a Swedish middle-aged general population and association with diabetes mellitus
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Elastase- and LPS-Exposed Cpa3(Cre/+) and ST2(-/-) Mice Develop Unimpaired Obstructive Pulmonary Disease

Cardenas, Eduardo; Alvarado-Vazquez, Perla Abigail; Mendez-Enriquez, Erika; Danielsson, Erik A. et al.

Part of Frontiers in Immunology, 2022

• DOI for Elastase- and LPS-Exposed Cpa3(Cre/+) and ST2(-/-) Mice Develop Unimpaired Obstructive Pulmonary Disease
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IgE cross-linking induces activation of human and mouse mast cell progenitors

Mendez-Enriquez, Erika; Salomonsson, Maya; Eriksson, Jens; Janson, Christer et al.

Part of Journal of Allergy and Clinical Immunology, p. 1458-1463, 2022

• DOI for IgE cross-linking induces activation of human and mouse mast cell progenitors
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Depletion of Mcpt8‐expressing cells reduces lung mast cells in mice with experimental asthma

Alvarado-Vazquez, Perla Abigail; Cardenas, Eduardo I.; Das, Avijit; Hallgren, Jenny

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 1363-1366, 2022

• DOI for Depletion of Mcpt8‐expressing cells reduces lung mast cells in mice with experimental asthma
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The proportion of FceRI+ blood monocytes increases with the degree of IgE sensitization in asthma

Salomonsson, Matilda; Cárdenas, Eduardo I.; Dahlin, Joakim S.; Kalm-Stephens, Pia et al.

Part of Journal of investigational allergology & clinical immunology, p. 489-491, 2022

• DOI for The proportion of FceRI+ blood monocytes increases with the degree of IgE sensitization in asthma

Use of spirometry-like measurements to monitor house dust mite-induced experimental asthma in mice

Alvarado-Vazquez, Perla A.; Mendez-Enriquez, Erika; Hallgren, Jenny

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2204-2207, 2021

• DOI for Use of spirometry-like measurements to monitor house dust mite-induced experimental asthma in mice
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Mast cell-derived serotonin enhances methacholine-induced airway hyperresponsiveness in house dust mite-induced experimental asthma

Mendez-Enriquez, Erika; Alvarado-Vazquez, Perla Abigail; Abma, Willem; Simonson, Oscar et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2057-2069, 2021

• DOI for Mast cell-derived serotonin enhances methacholine-induced airway hyperresponsiveness in house dust mite-induced experimental asthma

Asthma in combination with rhinitis and eczema is associated with a higher degree of type-2 inflammation and symptom burden than asthma alone

Blöndal, Viiu; Janson, Christer; Sundbom, Fredrik; Borres, Magnus P et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 3827-3829, 2021

• DOI for Asthma in combination with rhinitis and eczema is associated with a higher degree of type-2 inflammation and symptom burden than asthma alone
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Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors

Salomonsson, Maya; Dahlin, Joakim S.; Ungerstedt, Johanna; Hallgren, Jenny

Part of Frontiers in Immunology, 2020

• DOI for Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors
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Demonstration of human mast cell progenitors in the bone marrow

Salomonsson, Maya; Ungerstedt, Johanna; Alvarado-Vazquez, Perla A.; Hallgren, Jenny

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 456-460, 2020

• DOI for Demonstration of human mast cell progenitors in the bone marrow
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Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium

Hallgren, Jenny; Hellman, Lars; Maurer, Marcus; Nilsson, Gunnar P. et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 707-708, 2020

• DOI for Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium
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Circulating mast cell progenitors correlate with reduced lung function in allergic asthma

Salomonsson, Maya; Malinovschi, Andrei; Kalm-Stephens, Pia; Dahlin, Joakim S. et al.

Part of Clinical and Experimental Allergy, p. 874-882, 2019

• DOI for Circulating mast cell progenitors correlate with reduced lung function in allergic asthma
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Innate Immunity Induces the Accumulation of Lung Mast Cells During Influenza Infection

Zarnegar, Behdad; Westin, Annika; Evangelidou, Syrmoula; Hallgren, Jenny

Part of Frontiers in Immunology, 2018

• DOI for Innate Immunity Induces the Accumulation of Lung Mast Cells During Influenza Infection
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Influenza Infection in Mice Induces Accumulation of Lung Mast Cells through the Recruitment and Maturation of Mast Cell Progenitors

Zarnegar, Behdad; Mendez-Enriquez, Erika; Westin, Annika; Söderberg, Cecilia et al.

Part of Frontiers in Immunology, 2017

• DOI for Influenza Infection in Mice Induces Accumulation of Lung Mast Cells through the Recruitment and Maturation of Mast Cell Progenitors
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SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo

Pettersson, Hanna; Zarnegar, Behdad; Westin, Annika; Persson, Viktor et al.

Part of Scientific Reports, 2017

• DOI for SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo
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Lineage- CD34hi CD117int/hi FcϵRI+ cells in human blood constitute a rare population of mast cell progenitors

Dahlin, Joakim S; Malinovschi, Andrei; Öhrvik, Helena; Sandelin, Martin et al.

Part of Blood, p. 383-391, 2016

• DOI for Lineage- CD34hi CD117int/hi FcϵRI+ cells in human blood constitute a rare population of mast cell progenitors

Identification of Biological and Pharmaceutical Mast Cell- and Basophil-Related Targets

Klein, O.; Ngo-Nyekel, F.; Stefanache, T.; Torres, R. et al.

Part of Scandinavian Journal of Immunology, p. 465-472, 2016

• DOI for Identification of Biological and Pharmaceutical Mast Cell- and Basophil-Related Targets

Distinguishing Mast Cell Progenitors from Mature Mast Cells in Mice

Dahlin, Joakim S.; Ding, Zhoujie; Hallgren, Jenny

Part of Stem Cells and Development, p. 1703-1711, 2015

• DOI for Distinguishing Mast Cell Progenitors from Mature Mast Cells in Mice

Mouse Mast Cell Protease-6 and MHC Are Involved in the Development of Experimental Asthma

Cui, Yue; Dahlin, Joakim S.; Feinstein, Ricardo; Bankova, Lora G. et al.

Part of Journal of Immunology, p. 4783-4789, 2014

• DOI for Mouse Mast Cell Protease-6 and MHC Are Involved in the Development of Experimental Asthma

Prospective Isolation of Committed Mast Cell Progenitors from Mouse Blood

Dahlin, Joakim; Heyman, Birgitta; Hallgren, Jenny

Part of Scandinavian Journal of Immunology, p. 436-436, 2014

Does Cell Proliferation Contribute to the OVA-Induced Increase of Lung Mast Cell Progenitors in a Mouse Asthma Model?

Zarnegar, Behdad; Dahlin, Joakim; Westin, Annika; Hallgren Martinsson, Jenny

Part of Scandinavian Journal of Immunology, p. 463-463, 2014

Granule maturation in mast cells: Histamine in control

Hallgren, Jenny; Gurish, Michael F.

Part of European Journal of Immunology, p. 33-36, 2014

• DOI for Granule maturation in mast cells: Histamine in control

Committed mast cell progenitors in mouse blood differ in maturity between Th1 and Th2 strains

Dahlin, Joakim S; Heyman, Birgitta; Hallgren, Jenny

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 1333-1337, 2013

• DOI for Committed mast cell progenitors in mouse blood differ in maturity between Th1 and Th2 strains

Identification of committed mast cell progenitors in mouse blood

Dahlin, Joakim S.; Heyman, Birgitta; Hallgren, Jenny Martinsson

Part of Immunology, p. 175-176, 2013

Complement receptors 1 and 2 in murine antibody responses to IgM-complexed and uncomplexed sheep erythrocytes

Rutemark, Christian; Bergman, Anna; Getahun, Andrew; Hallgren, Jenny et al.

Part of PLOS ONE, 2012

• DOI for Complement receptors 1 and 2 in murine antibody responses to IgM-complexed and uncomplexed sheep erythrocytes
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CD11c(+) Cells Are Required for Antigen-Induced Increase of Mast Cells in the Lung

Dahlin, Joakim S; Feinstein, Ricardo; Cui, Yue; Heyman, Birgitta et al.

Part of Journal of Immunology, p. 3869-3877, 2012

• DOI for CD11c(+) Cells Are Required for Antigen-Induced Increase of Mast Cells in the Lung

IgE-Mediated Enhancement of CD4(+) T Cell Responses in Mice Requires Antigen Presentation by CD11c(+) Cells and Not by B Cells

Henningsson, Frida; Ding, Zhoujie; Dahlin, Joakim S.; Linkevicius, Marius et al.

Part of PLOS ONE, 2011

• DOI for IgE-Mediated Enhancement of CD4(+) T Cell Responses in Mice Requires Antigen Presentation by CD11c(+) Cells and Not by B Cells
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IgE Immune Complexes Stimulate an Increase in Lung Mast Cell Progenitors in a Mouse Model of Allergic Airway Inflammation

Dahlin, Joakim S.; Ivarsson, Martin A.; Heyman, Birgitta; Hallgren, Jenny

Part of PLoS One, 2011

• DOI for IgE Immune Complexes Stimulate an Increase in Lung Mast Cell Progenitors in a Mouse Model of Allergic Airway Inflammation

Mast cell progenitor trafficking and maturation

Hallgren, Jenny; Gurish, Michael F.

Part of Advances in Experimental Medicine and Biology, p. 14-28, 2011

• DOI for Mast cell progenitor trafficking and maturation

The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo

Collington, Sarah J; Hallgren, Jenny; Pease, James E; Jones, Tatiana G et al.

Part of Journal of Immunology, p. 6114-6123, 2010

• DOI for The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo

Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells

Jones, Tatiana G; Hallgren, Jenny; Humbles, Alison; Burwell, Timothy et al.

Part of Journal of Immunology, p. 5251-5260, 2009

• DOI for Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells

Genetic inversion in mast cell-deficient (W(sh)) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.

Nigrovic, Peter A; Gray, Daniel H D; Jones, Tatiana; Hallgren, Jenny et al.

Part of The American journal of pathology, p. 1693-1701, 2008

• DOI for Genetic inversion in mast cell-deficient (W(sh)) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.

Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue

Alcaide, Pilar; Jones, Tatiana G; Lord, Graham M; Glimcher, Laurie H et al.

Part of Journal of Experimental Medicine, p. 431-439, 2007

• DOI for Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue

Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors

Hallgren, Jenny; Jones, Tatiana G; Abonia, J Pablo; Xing, Wei et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 20478-20483, 2007

• DOI for Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors

Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung

Abonia, J Pablo; Hallgren, Jenny; Jones, Tatiana; Shi, Tong et al.

Part of Blood, p. 1588-1594, 2006

• DOI for Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung

Selected recent advances in understanding the role of human mast cells in health and disease

Levi-Schaffer, Francesca; Gibbs, Bernhard F.; Hallgren, Jenny; Pucillo, Carlo et al.

Part of Journal of Allergy and Clinical Immunology, p. 1833-1844, 2022

• DOI for Selected recent advances in understanding the role of human mast cells in health and disease

Mast Cells and Their Progenitors in Allergic Asthma

Mendez-Enriquez, Erika; Hallgren, Jenny

Part of Frontiers in Immunology, 2019

• DOI for Mast Cells and Their Progenitors in Allergic Asthma
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Mast cell progenitors: Origin, development and migration to tissues

Dahlin, Joakim S; Hallgren, Jenny

Part of Molecular Immunology, p. 9-17, 2015

• DOI for Mast cell progenitors: Origin, development and migration to tissues
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Pathways of murine mast cell development and trafficking: tracking the roots and routes of the mast cell

Hallgren, Jenny; Gurish, Michael F

Part of Immunological Reviews, p. 8-18, 2007

• DOI for Pathways of murine mast cell development and trafficking: tracking the roots and routes of the mast cell