Josefine Palle

Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Enblad, Anna Pia; Krali, Olga; Gezelius, Henrik; Lundmark, Anders et al.

Part of HemaSphere, 2025

• DOI for Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
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Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 protocol

Zeller, Bernward; Arad-Cohen, Nira; Cheuk, Daniel; De Moerloose, Barbara et al.

Part of Haematologica, p. 2873-2883, 2024

• DOI for Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 protocol
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Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study

Källström, Jonatan; Niinimäki, Riitta; Fredlund, Johan; Vogt, Hartmut et al.

Part of Haematologica, p. 2846-2853, 2024

• DOI for Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study
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Bone Marrow-Suppressive Treatment in Children Is Associated with Diminished IFN-γ Response from T Cells upon Polyclonal and Varicella Zoster Virus Peptide Stimulation

Tiselius, Eva; Sundberg, Emil; Andersson, Hanna; Höbinger, Anna et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Bone Marrow-Suppressive Treatment in Children Is Associated with Diminished IFN-γ Response from T Cells upon Polyclonal and Varicella Zoster Virus Peptide Stimulation
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Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease

Tierens, Anne; Arad-Cohen, Nira; Cheuk, Daniel; De Moerloose, Barbara et al.

Part of Journal of Clinical Oncology, p. 2174-2185, 2024

• DOI for Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease

Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Enblad, Anna Pia; Krali, Olga; Gezelius, Henrik; Lundmark, Anders et al.

Part of HemaSphere, 2025

• DOI for Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
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Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 protocol

Zeller, Bernward; Arad-Cohen, Nira; Cheuk, Daniel; De Moerloose, Barbara et al.

Part of Haematologica, p. 2873-2883, 2024

• DOI for Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 protocol
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Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study

Källström, Jonatan; Niinimäki, Riitta; Fredlund, Johan; Vogt, Hartmut et al.

Part of Haematologica, p. 2846-2853, 2024

• DOI for Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study
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Bone Marrow-Suppressive Treatment in Children Is Associated with Diminished IFN-γ Response from T Cells upon Polyclonal and Varicella Zoster Virus Peptide Stimulation

Tiselius, Eva; Sundberg, Emil; Andersson, Hanna; Höbinger, Anna et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Bone Marrow-Suppressive Treatment in Children Is Associated with Diminished IFN-γ Response from T Cells upon Polyclonal and Varicella Zoster Virus Peptide Stimulation
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Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease

Tierens, Anne; Arad-Cohen, Nira; Cheuk, Daniel; De Moerloose, Barbara et al.

Part of Journal of Clinical Oncology, p. 2174-2185, 2024

• DOI for Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease

Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children

Stratmann, Svea; Vesterlund, Mattias; Umer, Husen M.; Skaftason, Aron et al.

Part of Leukemia, p. 550-559, 2023

• DOI for Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children
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Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia

Karlsson, Lene; Cheuk, Daniel; De Moerloose, Barbara; Hasle, Henrik et al.

Part of British Journal of Haematology, p. 757-765, 2023

• DOI for Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia
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Abdominal Complications During Treatment for Pediatric Acute Myeloid Leukemia

Borgstedt-Bendixen, Sofie E.; Abrahamsson, Jonas; Ha, Shau-Yin; Koskenvuo, Minna et al.

Part of Journal of Pediatric Hematology/Oncology, p. 220-229, 2022

• DOI for Abdominal Complications During Treatment for Pediatric Acute Myeloid Leukemia

Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression

Stratmann, Svea; Yones, Sara A.; Garbulowski, Mateusz; Sun, Jitong et al.

Part of Blood Advances, p. 152-164, 2022

• DOI for Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression
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Germline GATA1s-generating mutations predispose to leukemia with acquired trisomy 21 and Down syndrome-like phenotype

Hasle, Henrik; Kline, Ronald M.; Kjeldsen, Eigil; Nik-Abdul-Rashid, Nik F. et al.

Part of Blood, p. 3159-3165, 2022

• DOI for Germline GATA1s-generating mutations predispose to leukemia with acquired trisomy 21 and Down syndrome-like phenotype

Low numbers of COVID-19 in Swedish pediatric oncology patients during the first pandemic year despite an open society

Sundberg, Emil; Georgantzi, Kleopatra; Langenskiöld, Cecilia; Król, Ladislav et al.

Part of Pediatric Blood & Cancer, 2022

• DOI for Low numbers of COVID-19 in Swedish pediatric oncology patients during the first pandemic year despite an open society
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A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias

Berglund, Eva Caroline; Barbany, Gisela; Orsmark-Pietras, Christina; Fogelstrand, Linda et al.

Part of Frontiers in Medicine, 2022

• DOI for A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias
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High need for intensive care in paediatric acute myeloid leukaemia: A population-based study

Ranta, Susanna; Broman, Lars Mikael; Abrahamsson, Jonas; Karlsson, Lene et al.

Part of Acta Paediatrica, p. 2235-2241, 2022

• DOI for High need for intensive care in paediatric acute myeloid leukaemia: A population-based study
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Familial platelet disorder due to germline exonic deletions in RUNX1: a diagnostic challenge with distinct alterations of the transcript isoform equilibrium

Engvall, Marie; Karlsson, Ylva; Kuchinskaya, Ekaterina; Jörnegren, Åsa et al.

Part of Leukemia and Lymphoma, p. 2311-2320, 2022

• DOI for Familial platelet disorder due to germline exonic deletions in RUNX1: a diagnostic challenge with distinct alterations of the transcript isoform equilibrium
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COVID-19 seroprevalence and clinical picture in Swedish pediatric oncology and hematology patients

Sundberg, Emil; Hoffman, Tove; Nilsson, Anna; Pahnke, Simon et al.

Part of Pediatric Blood & Cancer, 2022

• DOI for COVID-19 seroprevalence and clinical picture in Swedish pediatric oncology and hematology patients
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DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)

Krali, Olga; Palle, J; Bäcklin, Christofer; Abrahamsson, Jonas et al.

Part of Genes, 2021

• DOI for DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)
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Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets

Stratmann, Svea; Yones, Sara A.; Mayrhofer, Markus; Norgren, Nina et al.

Part of Blood Advances, p. 900-912, 2021

• DOI for Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets

Extracorporeal Membrane Oxygenation Support in Children With Hematologic Malignancies in Sweden

Ranta, Susanna; Kalzen, Hakan; Nilsson, Anna; von Schewelov, Katarina et al.

Part of Journal of pediatric hematology/oncology (Print), 2021

• DOI for Extracorporeal Membrane Oxygenation Support in Children With Hematologic Malignancies in Sweden

Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells

von Beek, Christopher; Alriksson, Linnéa; Palle, Josefine; Gustafson, Ann-Marie et al.

Part of PLOS ONE, 2021

• DOI for Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells
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Associations between pretherapeutic body mass index, outcome, and cytogenetic abnormalities in pediatric acute myeloid leukemia

Löhmann, Ditte J. A.; Asdahl, Peter H.; Abrahamsson, Jonas; Ha, Shau-Yin et al.

Part of Cancer Medicine, p. 6634-6643, 2019

• DOI for Associations between pretherapeutic body mass index, outcome, and cytogenetic abnormalities in pediatric acute myeloid leukemia
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Use of granulocyte colony-stimulating factor and risk of relapse in pediatric patients treated for acute myeloid leukemia according to NOPHO-AML 2004 and DB AML-01

Lohnnann, Ditte J. A.; Asdahl, Peter H.; Abrahamsson, Jonas; Ha, Shau-Yin et al.

Part of Pediatric Blood & Cancer, 2019

• DOI for Use of granulocyte colony-stimulating factor and risk of relapse in pediatric patients treated for acute myeloid leukemia according to NOPHO-AML 2004 and DB AML-01

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

Borssen, Magnus; Nordlund, Jessica; Haider, Zahra; Landfors, Mattias et al.

Part of Clinical Epigenetics, 2018

• DOI for DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia
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Complex and monosomal karyotype are distinct cytogenetic entities with an adverse prognostic impact in paediatric acute myeloid leukaemia: A NOPHO-DBH-AML study

Bager, Ninna; Juul-Dam, Kristian L.; Sandahl, Julie D.; Abrahamsson, Jonas et al.

Part of British Journal of Haematology, p. 618-628, 2018

• DOI for Complex and monosomal karyotype are distinct cytogenetic entities with an adverse prognostic impact in paediatric acute myeloid leukaemia: A NOPHO-DBH-AML study

Associations between neutrophil recovery time, infections and relapse in pediatric acute myeloid leukemia

Lohmann, Ditte J. A.; Asdahl, Peter H.; Abrahamsson, Jonas; Ha, Shau-Yin et al.

Part of Pediatric Blood & Cancer, 2018

• DOI for Associations between neutrophil recovery time, infections and relapse in pediatric acute myeloid leukemia

Extramedullary leukemia in children with acute myeloid leukemia: A population-based cohort study from the Nordic Society of Pediatric Hematology and Oncology (NOPHO)

Stove, Heidi Kristine; Sandahl, Julie Damgaard; Abrahamsson, Jonas; Asdahl, Peter H. et al.

Part of Pediatric Blood & Cancer, 2017

• DOI for Extramedullary leukemia in children with acute myeloid leukemia: A population-based cohort study from the Nordic Society of Pediatric Hematology and Oncology (NOPHO)

Outcome after intensive reinduction therapy and allogeneic stem cell transplant in paediatric relapsed acute myeloid leukaemia

Karlsson, Lene; Forestier, Erik; Hasle, Henrik; Jahnukainen, Kirsi et al.

Part of British Journal of Haematology, p. 592-602, 2017

• DOI for Outcome after intensive reinduction therapy and allogeneic stem cell transplant in paediatric relapsed acute myeloid leukaemia

Hyperleucocytosis in paediatric acute myeloid leukaemia: the challenge of white blood cell counts above 200 x 10⁹/l. The NOPHO experience 1984-2014

Zeller, Bernward; Glosli, Heidi; Forestier, Erik; Ha, Shau-Yin et al.

Part of British Journal of Haematology, p. 448-456, 2017

• DOI for Hyperleucocytosis in paediatric acute myeloid leukaemia: the challenge of white blood cell counts above 200 x 10⁹/l. The NOPHO experience 1984-2014

Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy

Dalin, Frida; Adamus, Grazyna; Yang, Sufang; Landgren, Eva et al.

Part of Ophthalmology, p. 1401-1404, 2016

• DOI for Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

Lindqvist, C. Mårten; Lundmark, Anders; Nordlund, Jessica; Freyhult, Eva et al.

Part of Oncotarget, p. 64071-64088, 2016

• DOI for Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy

Dalin, Frida; Adamus, Grazyna; Yang, Sufang; Landgren, Eva et al.

Part of Ophthalmology, p. 1401-1404, 2016

• DOI for Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy

Acute Myeloid Leukemia in Adolescents and Young Adults Treated in Pediatric and Adult Departments in the Nordic Countries

Wennstrom, Lovisa; Edslev, Pernille Wendtland; Abrahamsson, Jonas; Norgaard, Jan Maxwell et al.

Part of Pediatric Blood & Cancer, p. 83-92, 2016

• DOI for Acute Myeloid Leukemia in Adolescents and Young Adults Treated in Pediatric and Adult Departments in the Nordic Countries

Residual disease detected by flow cytometry is an independent predictor of survival in childhood acute myeloid leukaemia; results of the NOPHO-AML 2004 study

Tierens, Anne; Bjorklund, Elizabeth; Siitonen, Sanna; Marquart, Hanne Vibeke et al.

Part of British Journal of Haematology, p. 600-609, 2016

• DOI for Residual disease detected by flow cytometry is an independent predictor of survival in childhood acute myeloid leukaemia; results of the NOPHO-AML 2004 study

Effect of age and body weight on toxicity and sur vival in pediatric acute myeloid leukemia: results from NOPHO-AML 2004

Lohmann, Ditte J. A.; Abrahamsson, Jonas; Ha, Shau-Yin; Jonsson, Olafur G. et al.

Part of Haematologica, p. 1359-1367, 2016

• DOI for Effect of age and body weight on toxicity and sur vival in pediatric acute myeloid leukemia: results from NOPHO-AML 2004

Trisomy 8 in pediatric acute myeloid leukemia: A NOPHO-AML study

Laursen, Anne Cathrine Lund; Sandahl, Julie Damgaard; Kjeldsen, Eigil; Abrahamsson, Jonas et al.

Part of Genes, Chromosomes and Cancer, p. 719-726, 2016

• DOI for Trisomy 8 in pediatric acute myeloid leukemia: A NOPHO-AML study

The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

Lindqvist, C Mårten; Nordlund, Jessica; Ekman, Diana; Johansson, Anna et al.

Part of Human Mutation, p. 118-128, 2015

• DOI for The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer; Zachariadis, Vasilios; Cavelier, Lucia et al.

Part of Clinical Epigenetics, 2015

• DOI for DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
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The applicability of the WHO classification in paediatric AML. A NOPHO-AML study

Sandahl, Julie D.; Kjeldsen, Eigil; Abrahamsson, Jonas; Ha, Shau-Yin et al.

Part of British Journal of Haematology, p. 859-867, 2015

• DOI for The applicability of the WHO classification in paediatric AML. A NOPHO-AML study

Effect of Age and Weight on Toxicity and Survival in Pediatric Acute Myeloid Leukemia

Lohmann, Ditte Juel Adolfsen; Abrahamson, Jonas; Ha, Shau Yin; Jonsson, Olafur G. et al.

Part of Blood, 2015

Toxicity is Associated with Age in Nopho-Aml 2004

Lohmann, D. J. A.; Abrahamsson, J.; Ha, S. Y.; Jonsson, O. G. et al.

Part of Pediatric Blood & Cancer, 2014

Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study

Sandahl, Julie Damgaard; Kjeldsen, Eigil; Abrahamsson, Jonas; Ha, Shau-Yin et al.

Part of Genes, Chromosomes and Cancer, p. 667-675, 2014

• DOI for Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study

Anthracycline Type during Induction Associated with Outcome in Pediatric t(8;21) and Inv(16) AML

Hasle, Henrik; Abrahamsson, Jonas; De Bont, Evelina S.; de Haas, Valerie et al.

Part of Blood, 2014

DNA Methylation-Based Subtype Prediction for Pediatric Acute Lymphoblastic Leukemia (ALL)

Nordlund, Jessica; Backlin, Christofer; Zachariadis, Vasilios; Cavelier, Lucia et al.

Part of Blood, 2014

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer L; Wahlberg, Per; Busche, Stephan et al.

Part of Genome Biology, 2013

• DOI for Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Whole-genome-amplified DNA as a source for mutational analysis underestimates the frequency of mutations in pediatric acute myeloid leukemia

Rosenquist, Richard; Ehrencrona, H.; Hasle, H.; Palle, Josefine et al.

Part of Leukemia, p. 510-512, 2013

• DOI for Whole-genome-amplified DNA as a source for mutational analysis underestimates the frequency of mutations in pediatric acute myeloid leukemia

Outcome of poor response paediatric AML using early SCT

Wareham, Neval E.; Heilmann, Carsten; Abrahamsson, Jonas; Forestier, Erik et al.

Part of European Journal of Haematology, p. 187-194, 2013

• DOI for Outcome of poor response paediatric AML using early SCT

Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004

Hasle, Henrik; Abrahamsson, Jonas; Forestier, Erik; Ha, Shau-Yin et al.

Part of Blood, p. 978-984, 2012

• DOI for Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004

Response: High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia

Staffas, Anna; Kanduri, Meena; Hovland, Randi; Rosenquist, Richard et al.

Part of Blood, p. 1087-1088, 2012

• DOI for Response: High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia

Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

Staffas, Anna; Kanduri, Meena; Hovland, Randi; Rosenquist, Richard et al.

Part of Blood, p. 5905-5913, 2011

• DOI for Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

Response-Guided Induction Therapy in Pediatric Acute Myeloid Leukemia With Excellent Remission Rate

Abrahamsson, Jonas; Forestier, Erik; Heldrup, Jesper; Jahnukainen, Kirsi et al.

Part of Journal of Clinical Oncology, p. 310-315, 2011

• DOI for Response-Guided Induction Therapy in Pediatric Acute Myeloid Leukemia With Excellent Remission Rate

Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia

Palle, Josefine; Frost, Britt-Marie; Petersson, Curt; Hasle, Henrik et al.

Part of Anti-Cancer Drugs, p. 7-14, 2009

• DOI for Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia

Etoposide pharmacokinetics in children treated for acute myeloid leukemia

Palle, Josefine; Frost, Britt-Marie; Gustafsson, Göran; Hellebostad, Marit et al.

Part of Anti-Cancer Drugs, p. 1087-1094, 2006

• DOI for Etoposide pharmacokinetics in children treated for acute myeloid leukemia

Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage.

Palle, J; Frost, B M; Forestier, E; Gustafsson, G et al.

Part of Br J Haematol, p. 189-98, 2005

Supportive care in pediatric acute myeloid leukemia:Expert-based recommendations of the NOPHO-DB-SHIP consortium

Arad-Cohen, Nira; Zeller, Bernward; Abrahamsson, Jonas; Fernandez Navarro, Jose Maria et al.

Part of Expert Review of Anticancer Therapy, p. 1183-1196, 2022

• DOI for Supportive care in pediatric acute myeloid leukemia:Expert-based recommendations of the NOPHO-DB-SHIP consortium

Acute myeloid leukemia (AML) with t(7;12)(q36;p13) is associated with infancy and trisomy 19: Data from Nordic Society for Pediatric Hematology and Oncology (NOPHO-AML) and review of the literature

Espersen, Anne Dorte Lerche; Noren-Nystrom, Ulrika; Abrahamsson, Jonas; Ha, Shau-Yin et al.

Part of Genes, Chromosomes and Cancer, p. 359-365, 2018

• DOI for Acute myeloid leukemia (AML) with t(7;12)(q36;p13) is associated with infancy and trisomy 19: Data from Nordic Society for Pediatric Hematology and Oncology (NOPHO-AML) and review of the literature

Optimizing Chemotherapy in Childhood Acute Myeloid Leukemia

Palle, Josefine

2008

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SUPPLEMENTARY MATERIAL: Transcriptomic analysis reveals pro-inflammatory signatures associated with acute myeloid leukemia progression

Stratmann, Svea; Yones, Sara A.; Garbulowski, Mateusz; Sun, Jitong et al.

2021

SUPPLEMENTAL INFORMATION FOR: Transcriptomic analysis reveals pro-inflammatory signatures associated with acute myeloid leukemia progression

Stratmann, Svea; Yones, Sara A.; Garbulowski, Mateusz; Sun, Jitong et al.

2020

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