Gabriela Rosen

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

Rahmanto, Aldwin Suryo; Savov, Vasil; Brunner, Andrä; Bolin, Sara et al.

Part of EMBO Journal, p. 2192-2212, 2016

• DOI for FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
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Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Åkerblom, Björn; Zang, Guangxiang; Zhuang, Zhen W.; Calounova, Gabriela et al.

Part of Molecular Oncology, p. 333-346, 2012

• DOI for Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis
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Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

Gustafsson, Karin; Calounova, Gabriela; Hjelm, Fredrik; Kriz, Vitezslav et al.

Part of BMC Immunology, p. 3, 2011

• DOI for Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells
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Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Funa, Nina S; Kriz, Vitezslav; Zang, Guangxiang; Calounova, Gabriela et al.

Part of Cancer Research, p. 2141-2148, 2009

• DOI for Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Ohata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka et al.

Part of Cell Death and Differentiation, p. 1915-1929, 2025

• DOI for The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
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ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

Mainwaring, Oliver; Weishaupt, Holger; Zhao, Miao; Rosén, Gabriela et al.

Part of Nature Communications, 2023

• DOI for ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors
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Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

Weishaupt, Holger; Čančer, Matko; Rosén, Gabriela; Holmberg, Karl O. et al.

Part of Neuro-Oncology, p. 97-107, 2023

• DOI for Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas
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Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Borgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao et al.

Part of Cancer Research, p. 4586-4603, 2022

• DOI for Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
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Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

Zhang, Hua; Polavarapu, Vamsi Krishna; Xing, Pengwei; Zhao, Miao et al.

Part of Genome Research, p. 150-161, 2022

• DOI for Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples
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The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Ohata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka et al.

Part of Cell Death and Differentiation, p. 1915-1929, 2025

• DOI for The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
• Download full text (pdf) of The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

Mainwaring, Oliver; Weishaupt, Holger; Zhao, Miao; Rosén, Gabriela et al.

Part of Nature Communications, 2023

• DOI for ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors
• Download full text (pdf) of ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

Weishaupt, Holger; Čančer, Matko; Rosén, Gabriela; Holmberg, Karl O. et al.

Part of Neuro-Oncology, p. 97-107, 2023

• DOI for Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas
• Download full text (pdf) of Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Borgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao et al.

Part of Cancer Research, p. 4586-4603, 2022

• DOI for Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
• Download full text (pdf) of Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

Zhang, Hua; Polavarapu, Vamsi Krishna; Xing, Pengwei; Zhao, Miao et al.

Part of Genome Research, p. 150-161, 2022

• DOI for Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples
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BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara et al.

Part of Cell Death and Disease, 2019

• DOI for BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
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Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Čančer, Matko; Hutter, Sonja; Holmberg Olausson, Karl; Rosén, Gabriela et al.

Part of Cell Stem Cell, p. 855-870, 2019

• DOI for Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
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GMYC: A Novel Inducible Transgenic Model of Group 3 Medulloblastoma

Weishaupt, Holger; Mainwaring, Oliver; Hutter, Sonja; Kalushkova, Antonia et al.

Part of Neuro-Oncology, p. 137-137, 2018

• DOI for GMYC: A Novel Inducible Transgenic Model of Group 3 Medulloblastoma

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

Rahmanto, Aldwin Suryo; Savov, Vasil; Brunner, Andrä; Bolin, Sara et al.

Part of EMBO Journal, p. 2192-2212, 2016

• DOI for FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
• Download full text (pdf) of FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Åkerblom, Björn; Zang, Guangxiang; Zhuang, Zhen W.; Calounova, Gabriela et al.

Part of Molecular Oncology, p. 333-346, 2012

• DOI for Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis
• Download full text (pdf) of Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

Gustafsson, Karin; Calounova, Gabriela; Hjelm, Fredrik; Kriz, Vitezslav et al.

Part of BMC Immunology, p. 3, 2011

• DOI for Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells
• Download full text (pdf) of Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Calounova, Gabriela; Livera, Gabriel; Zhang, X-Q; Liu, Kui et al.

Part of PLOS ONE, 2010

• DOI for The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Funa, Nina S; Kriz, Vitezslav; Zang, Guangxiang; Calounova, Gabriela et al.

Part of Cancer Research, p. 2141-2148, 2009

• DOI for Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Impaired glucose homeostasis in Shb-/- mice

Åkerblom, Björn; Barg, Sebastian; Calounova, Gabriela; Mokhtari, Dariush et al.

Part of Journal of Endocrinology, p. 271-279, 2009

• DOI for Impaired glucose homeostasis in Shb-/- mice

Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

Kriz, Vitezslav; Mares, Jaroslav; Wentzel, Parri; Funa, Nina S. et al.

Part of Developmental Dynamics, p. 2485-2492, 2007

• DOI for Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

CDK2 as a therapeutic target in MYC-driven medulloblastoma

Borgenvik, Anna; Rosén, Gabriela; Holmberg Olausson, Karl; Larsson, Lars-Gunnar et al.

Photoreceptor-positive cells of tumor origin in MYC-driven Group 3 medulloblastoma

Zhao, Miao; Mainwaring, Oliver; Rosén, Gabriela; Rijpkema, Sanne et al.

Targeting SOX2 in glioblastoma cells reveals heterogeneity in SOX2 dependency

Dalmo, Erika; Rosén, Gabriela; Niklasson, Mia; Bergström, Tobias et al.