Konstantin Gängel

FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis

Sountoulidis, Alexandros; Theelke, Jonas; Liontos, Andreas; Firsova, Alexandra B. et al.

Part of Nature Communications, 2026

• DOI for FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis
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A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver

Pietilä, Riikka; Genové, Guillem; Mocci, Giuseppe; Miao, Yuyang et al.

Part of EMBO Reports, p. 5326-5359, 2025

• DOI for A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
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Intravital Imaging of Disease Mechanisms in a Mouse Model of CCM Skin Lesions-Brief Report

Orlich, Michael M.; Norrén, Amanda; Desai, Malavika; Holm, Annegret et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 113-118, 2025

• DOI for Intravital Imaging of Disease Mechanisms in a Mouse Model of CCM Skin Lesions-Brief Report
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Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium

Schoofs, Hans; Daubel, Nina; Schnabellehner, Sarah; Grönloh, Max L. B. et al.

Part of Nature, p. 465-475, 2025

• DOI for Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium
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Cdc42 is crucial for mural cell migration, proliferation and patterning of the retinal vasculature

Alvarez-Aznar, Alberto; Desai, Malavika; Orlich, Michael M.; Vázquez-Liébanas, Elisa et al.

Part of Vascular pharmacology, 2025

• DOI for Cdc42 is crucial for mural cell migration, proliferation and patterning of the retinal vasculature
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FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis

Sountoulidis, Alexandros; Theelke, Jonas; Liontos, Andreas; Firsova, Alexandra B. et al.

Part of Nature Communications, 2026

• DOI for FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis
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A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver

Pietilä, Riikka; Genové, Guillem; Mocci, Giuseppe; Miao, Yuyang et al.

Part of EMBO Reports, p. 5326-5359, 2025

• DOI for A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
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Intravital Imaging of Disease Mechanisms in a Mouse Model of CCM Skin Lesions-Brief Report

Orlich, Michael M.; Norrén, Amanda; Desai, Malavika; Holm, Annegret et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 113-118, 2025

• DOI for Intravital Imaging of Disease Mechanisms in a Mouse Model of CCM Skin Lesions-Brief Report
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Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium

Schoofs, Hans; Daubel, Nina; Schnabellehner, Sarah; Grönloh, Max L. B. et al.

Part of Nature, p. 465-475, 2025

• DOI for Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium
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Cdc42 is crucial for mural cell migration, proliferation and patterning of the retinal vasculature

Alvarez-Aznar, Alberto; Desai, Malavika; Orlich, Michael M.; Vázquez-Liébanas, Elisa et al.

Part of Vascular pharmacology, 2025

• DOI for Cdc42 is crucial for mural cell migration, proliferation and patterning of the retinal vasculature
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Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage

Vázquez-Liébanas, Elisa; Mocci, Giuseppe; Li, Weihan; Laviña, Bàrbara et al.

Part of Cell Reports, 2024

• DOI for Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage
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Incongruence between transcriptional and vascular pathophysiological cell states

Fernandez-Chacon, Macarena; Muhleder, Severin; Regano, Alvaro; Garcia-Ortega, Lourdes et al.

Part of Nature Cardiovascular Research, p. 530-549, 2023

• DOI for Incongruence between transcriptional and vascular pathophysiological cell states
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Cellular Origin of Sporadic CCMs

Betsholtz, Christer; Gängel, Konstantin; Mäkinen, Taija

Part of New England Journal of Medicine, p. 1291-1291, 2022

• DOI for Cellular Origin of Sporadic CCMs

Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow

Orlich, Michael M.; Dieguez-Hurtado, Rodrigo; Muehlfriedel, Regine; Sothilingam, Vithiyanjali et al.

Part of Circulation Research, p. 308-327, 2022

• DOI for Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow
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Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines

Alvarez, Alberto; Martinez-Corral, Ines; Daubel, Nina; Betsholtz, Christer et al.

Part of Transgenic research, p. 53-68, 2020

• DOI for Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines
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Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization

Yanagida, Keisuke; Engelbrecht, Eric; Niaudet, Colin; Jung, Bongnam et al.

Part of Developmental Cell, p. 779-+, 2020

• DOI for Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization

Integrins are required for synchronous ommatidial rotation in the Drosophila eye linking planar cell polarity signalling to the extracellular matrix

Thuveson, Maria; Gängel, Konstantin; Collu, Giovanna M.; Chin, Mei-ling et al.

Part of Open Biology, 2019

• DOI for Integrins are required for synchronous ommatidial rotation in the Drosophila eye linking planar cell polarity signalling to the extracellular matrix
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CDC42 deletion elicits cerebral vascular malformations via increased MEKK3-dependent KLF4 expression

Castro, Marco; Laviña, Bàrbara; Ando, Koji; Alvarez-Aznar, Alberto et al.

Part of Circulation Research, p. 1240-1252, 2019

• DOI for CDC42 deletion elicits cerebral vascular malformations via increased MEKK3-dependent KLF4 expression

Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment

Collu, Giovanna M.; Jenny, Andreas; Gängel, Konstantin; Mirkovic, Ivana et al.

Part of PLOS Genetics, 2018

• DOI for Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment
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Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

Laviña, Bàrbara; Castro, Marco; Niaudet, Colin; Cruys, Bert et al.

Part of Development, 2018

• DOI for Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Niaudet, Colin; Hofmann, Jennifer J.; Mae, Maarja A.; Jung, Bongnam et al.

Part of PLOS ONE, 2015

• DOI for Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Endocytosis regulates VEGF signalling during angiogenesis

Gängel, Konstantin; Betsholtz, Christer

Part of Nature Cell Biology, p. 233-235, 2013

• DOI for Endocytosis regulates VEGF signalling during angiogenesis

New imaging methods and tools to study vascular biology

Lavina, Barbara; Gängel, Konstantin

Part of Current opinion in hematology, p. 258-266, 2015

• DOI for New imaging methods and tools to study vascular biology

Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations: Cdc42 and vascular malformations

Laviña, Bàrbara; Castro, Marco; Niaudet, Colin; Bert, Cruys et al.

Resilience of lymphatic endothelium through isotropic stretch-induced cytoskeletal regulation of puzzle cell shape

Schoofs, Hans; Daubel, Nina; Schnabellehner, Sarah; Grönloh, Max et al.