Mariangela Pellegrini
Specialist physician at Department of Surgical Sciences; Anaesthesiology and Intensive Care
- E-mail:
- mariangela.pellegrini@uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 70, 1tr
751 85 Uppsala - Postal address:
- Akademiska sjukhuset, ingång 70, 1tr
751 85 UPPSALA
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Short presentation
Consultant at the Intensive Care Unit, AnOpIVA, Akademiska sjukhuset, Uppsala.
Post-doctoral studies, Dept. of Surgical Sciences, Uppsala University, Uppsala.
My research explores pathophysiological mechanisms characterising respiratory mechanics during mechanical ventilation in critically ill patients. I conduct both translational and clinical research. I master lung mechanics and several lung imaging techniques (e.g., computed tomography, electrical impedance tomography) and MatLab.
Keywords
- acute respiratory distress syndrome
- acute respiratory failure
- clinical research
- computed tomography
- intensive care
- lung
- lung imaging
- mechanical ventilation
- physiology
- respiratory mechanics
- synchrotron radiation computed tomography
- translational research
Publications
Recent publications
- Body mass index is associated with pulmonary gas and blood distribution mismatch in COVID-19 acute respiratory failure (2024)
- Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury (2024)
- Impact of airway closure and lung collapse on inhaled nitric oxide effect in acute lung injury (2024)
- Lung impedance changes during awake prone positioning in COVID-19 (2024)
- Positive end-expiratory pressure limits inspiratory effort through modulation of the effort-to-drive ratio (2024)
All publications
Articles
- Body mass index is associated with pulmonary gas and blood distribution mismatch in COVID-19 acute respiratory failure (2024)
- Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury (2024)
- Impact of airway closure and lung collapse on inhaled nitric oxide effect in acute lung injury (2024)
- Lung impedance changes during awake prone positioning in COVID-19 (2024)
- Positive end-expiratory pressure limits inspiratory effort through modulation of the effort-to-drive ratio (2024)
- ESICM guidelines on acute respiratory distress syndrome (2023)
- Early mobilisation in critically ill COVID-19 patients (2023)
- Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave (2022)
- Limitations of the ARDS criteria during high-flow oxygen or non-invasive ventilation (2022)
- Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients (2022)
- Variation in communication and family visiting policies in intensive care within and between countries during the Covid-19 pandemic (2022)
- Inspiratory Efforts, Positive End-Expiratory Pressure, and External Resistances Influence Intraparenchymal Gas Redistribution in Mechanically Ventilated Injured Lungs (2021)
- A quantitative analysis of extension and distribution of lung injury in COVID-19 (2021)
- Expiratory Resistances Prevent Expiratory Diaphragm Contraction, Flow Limitation, and Lung Collapse (2020)
- The use of positive end expiratory pressure in patients affected by COVID-19 (2020)
- Individual Airway Closure Characterized In Vivo by Phase-Contrast CT Imaging in Injured Rabbit Lung (2019)
- Expiratory Resistances Prevent Expiratory Diaphragm Contraction, Flow Limitation, and Lung Collapse (2019)
- Regional Behavior of Airspaces During Positive Pressure Reduction Assessed by Synchrotron Radiation Computed Tomography (2019)
- The Effect of Positive End-Expiratory Pressure on Lung Micromechanics Assessed by Synchrotron Radiation Computed Tomography in an Animal Model of ARDS (2019)
- The Effects of Positive End-Expiratory Pressure on Transpulmonary Pressure and Recruitment-Derecruitment During Neurally Adjusted Ventilator Assist (2019)
- Atelectasis is inversely proportional to transpulmonary pressure during weaning from ventilator support in a large animal model (2018)
- Not only pendelluft: multifold local inspiratory air-redistribution events continuously occur in collapsible lungs. (2018)
- Onset and Magnitude of Pendelluft During Spontaneous Breathing Depend on Lung Volume (2018)
- Multiple Transients of Local Gas Redistribution During Spontaneous Breathing Are Influenced by Ventilatory Settings (2018)
- Dynamic Mechanical Interactions Between Neighboring Airspaces Determine Cyclic Opening and Closure in Injured Lung (2017)
- The Diaphragm Acts as a Brake During Expiration to Prevent Lung Collapse (2017)
- Robustness of two different methods of monitoring respiratory system compliance during mechanical ventilation. (2017)
- Monitoring of total positive end-expiratory pressure during mechanical ventilation by artificial neural networks (2017)
- Effects of superimposed tissue weight on regional compliance of injured lungs (2016)
- High PEEP Reduces Recruitment/Derecruitment During Neurally Adjusted Ventilatory Assist in Mild Experimental ARDS (2016)
- Role Of Parenchymal Interdependence In The Short-Term Dynamics Of Recruitment/derecruitment In Injured Lung (2015)
- Can Expiratory Electrical Diaphragmatic Activity Guide Setting Of Positive End-Expiratory Pressure During Spontaneous Breathing In Acute Respiratory Failure? (2015)
Books
Conferences
