Ananya Roy

24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism

Wikvall, Kjell; Olsson, Frida; Wåhlén, Erik; Roy, Ananya et al.

Part of Neurochemistry International, 2026

• DOI for 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism
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Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap

Ruiz-Moreno, Cristian; Salas, Sergio Marco; Samuelsson, Erik; Minaeva, Mariia et al.

Part of Neuro-Oncology, p. 2281-2295, 2025

• DOI for Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap
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Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression

Wicher, Grzegorz; Roy, Ananya; Vaccaro, Alessandra; Vemuri, Kalyani et al.

Part of Neuro-Oncology Advances, 2025

• DOI for Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression
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On-chip fabrication of tailored 3D hydrogel scaffolds to model cancer cell invasion and interaction with endothelial cells

Cantoni, Federico; Barbe, Laurent; Roy, Ananya; Wicher, Grzegorz et al.

Part of APL Bioengineering, 2024

• DOI for On-chip fabrication of tailored 3D hydrogel scaffolds to model cancer cell invasion and interaction with endothelial cells
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Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements

Iniguez-Munoz, Sandra; Llinas-Arias, Pere; Ensenyat-Mendez, Miquel; Bedoya-Lopez, Andres F. et al.

Part of Cellular and Molecular Life Sciences (CMLS), 2024

• DOI for Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements
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24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism

Wikvall, Kjell; Olsson, Frida; Wåhlén, Erik; Roy, Ananya et al.

Part of Neurochemistry International, 2026

• DOI for 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism
• Download full text (pdf) of 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism

Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap

Ruiz-Moreno, Cristian; Salas, Sergio Marco; Samuelsson, Erik; Minaeva, Mariia et al.

Part of Neuro-Oncology, p. 2281-2295, 2025

• DOI for Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap
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Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression

Wicher, Grzegorz; Roy, Ananya; Vaccaro, Alessandra; Vemuri, Kalyani et al.

Part of Neuro-Oncology Advances, 2025

• DOI for Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression
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On-chip fabrication of tailored 3D hydrogel scaffolds to model cancer cell invasion and interaction with endothelial cells

Cantoni, Federico; Barbe, Laurent; Roy, Ananya; Wicher, Grzegorz et al.

Part of APL Bioengineering, 2024

• DOI for On-chip fabrication of tailored 3D hydrogel scaffolds to model cancer cell invasion and interaction with endothelial cells
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Leveraging base-pair mammalian constraint to understand genetic variation and human disease

Sullivan, Patrick F.; Meadows, Jennifer; Gazal, Steven; Phan, BaDoi N. et al.

Part of Science, p. 367-+, 2023

• DOI for Leveraging base-pair mammalian constraint to understand genetic variation and human disease

Using evolutionary constraint to define novel candidate driver genes in medulloblastoma

Roy, Ananya; Sakthikumar, Sharadha; Kozyrev, Sergey V.; Nordin, Jessika et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2023

• DOI for Using evolutionary constraint to define novel candidate driver genes in medulloblastoma
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Mast Cells Limit Ear Swelling Independently of the Chymase Mouse Mast Cell Protease 4 in an MC903-Induced Atopic Dermatitis-Like Mouse Model

Svanberg, Sofie; Li, Zhiqiang; Öhlund, Pontus; Roy, Ananya et al.

Part of International Journal of Molecular Sciences, 2020

• DOI for Mast Cells Limit Ear Swelling Independently of the Chymase Mouse Mast Cell Protease 4 in an MC903-Induced Atopic Dermatitis-Like Mouse Model
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Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression

Xiong, Anqi; Roy, Ananya; Spyrou, Argyris; Weishaupt, Holger et al.

Part of Cancers, 2020

• DOI for Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression
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Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes

Sakthikumar, Sharadha; Roy, Ananya; Haseeb, Lulu; Pettersson, Mats E. et al.

Part of Genome Biology, 2020

• DOI for Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes
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Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Roy, Ananya; Libard, Sylwia; Weishaupt, Holger; Gustavsson, Ida et al.

Part of Frontiers in Oncology, 2017

• DOI for Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
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Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression

Roy, Ananya; Attarha, Sanaz; Weishaupt, Holger; Edqvist, Per-Henrik et al.

Part of Oncotarget, p. 24815-24827, 2017

• DOI for Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
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Targeting metastasis in mammary carcinoma: functional analysis of serglycin proteoglycan (and the chymase mMCP-4)

Roy, Ananya; Etal, Damla; Hedenqvist, Patricia; Li, Zhiqiang et al.

Part of Scandinavian Journal of Immunology, p. 313-313, 2017

Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3 beta expression and inhibition of STAT3 activation

Attarha, Sanaz; Roy, Ananya; Westermark, Bengt; Tchougounova, Elena

Part of Cellular Signalling, p. 81-92, 2017

• DOI for Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3 beta expression and inhibition of STAT3 activation

Serglycin proteoglycans limit enteropathy in Trichinella spiralis-infected mice

Roy, Ananya; Sawesi, Osama; Pettersson, Ulrika A.; Dagälv, Anders et al.

Part of BMC Immunology, 2016

• DOI for Serglycin proteoglycans limit enteropathy in Trichinella spiralis-infected mice
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Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma

Roy, Ananya; Femel, Julia; Huijbers, Elisabeth J. M.; Spillmann, Dorothe et al.

Part of PLOS ONE, 2016

• DOI for Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma
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Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Part of Oncotarget, p. 23647-23661, 2015

• DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
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Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

Roy, Ananya; Ganesh, Goutham; Sippola, Helena; Bolin, Sara et al.

Part of Journal of Biological Chemistry, p. 237-250, 2014

• DOI for Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements

Iniguez-Munoz, Sandra; Llinas-Arias, Pere; Ensenyat-Mendez, Miquel; Bedoya-Lopez, Andres F. et al.

Part of Cellular and Molecular Life Sciences (CMLS), 2024

• DOI for Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements
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Mast Cells as Sentinels: Role of serglycin and mast cell proteases in infection and inflammation

Roy, Ananya

2012

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Microengineering a cell co-culture platform for glioblastoma cell migration and intravasation studies

Cantoni, Federico; Barbe, Laurent; Roy, Ananya; Wicher, Grzegorz K. et al.