Ananya Roy

Two translocation mechanisms drive neural stem cell dissemination into the human fetal cortex

Wimmer, Ryszard; Avalos, Clarisse Brunet; Lestienne, Pauline; Coquand, Laure et al.

Ingår i Neuron, s. 2165-2182, 2026

• DOI för Two translocation mechanisms drive neural stem cell dissemination into the human fetal cortex
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Non-coding somatic single-nucleotide variations affecting glioblastoma-specific enhancer elements regulate tumor-promoting gene networks

Iñiguez-Muñoz, Sandra; Llinàs-Arias, Pere; Ensenyat-Mendez, Miquel; Bedoya-López, Andrés F. et al.

Ingår i Genes and Diseases, 2026

• DOI för Non-coding somatic single-nucleotide variations affecting glioblastoma-specific enhancer elements regulate tumor-promoting gene networks
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Rare germline variants contribute to glioma predisposition: Whole-genome analysis of a regional cohort of glioma patients

Rosenbaum, Adam; Wibom, Carl; Hammermeister Suger, Austin; Pensch, Raphaela et al.

Ingår i Neuro-Oncology Advances, 2026

• DOI för Rare germline variants contribute to glioma predisposition: Whole-genome analysis of a regional cohort of glioma patients
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24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism

Wikvall, Kjell; Olsson, Frida; Wåhlén, Erik; Roy, Ananya et al.

Ingår i Neurochemistry International, 2026

• DOI för 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism
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Heparan sulfate N-deacetylase/N-sulfotransferase-1 regulates glioblastoma cell migration and invasion

Spyrou, Argyris; Roy, Ananya; Xiong, Anqi; Kundu, Soumi et al.

Ingår i Matrix Biology, s. 1-15, 2025

• DOI för Heparan sulfate N-deacetylase/N-sulfotransferase-1 regulates glioblastoma cell migration and invasion

Two translocation mechanisms drive neural stem cell dissemination into the human fetal cortex

Wimmer, Ryszard; Avalos, Clarisse Brunet; Lestienne, Pauline; Coquand, Laure et al.

Ingår i Neuron, s. 2165-2182, 2026

• DOI för Two translocation mechanisms drive neural stem cell dissemination into the human fetal cortex
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Non-coding somatic single-nucleotide variations affecting glioblastoma-specific enhancer elements regulate tumor-promoting gene networks

Iñiguez-Muñoz, Sandra; Llinàs-Arias, Pere; Ensenyat-Mendez, Miquel; Bedoya-López, Andrés F. et al.

Ingår i Genes and Diseases, 2026

• DOI för Non-coding somatic single-nucleotide variations affecting glioblastoma-specific enhancer elements regulate tumor-promoting gene networks
• Ladda ner fulltext (pdf) av Non-coding somatic single-nucleotide variations affecting glioblastoma-specific enhancer elements regulate tumor-promoting gene networks

Rare germline variants contribute to glioma predisposition: Whole-genome analysis of a regional cohort of glioma patients

Rosenbaum, Adam; Wibom, Carl; Hammermeister Suger, Austin; Pensch, Raphaela et al.

Ingår i Neuro-Oncology Advances, 2026

• DOI för Rare germline variants contribute to glioma predisposition: Whole-genome analysis of a regional cohort of glioma patients
• Ladda ner fulltext (pdf) av Rare germline variants contribute to glioma predisposition: Whole-genome analysis of a regional cohort of glioma patients

24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism

Wikvall, Kjell; Olsson, Frida; Wåhlén, Erik; Roy, Ananya et al.

Ingår i Neurochemistry International, 2026

• DOI för 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism
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Heparan sulfate N-deacetylase/N-sulfotransferase-1 regulates glioblastoma cell migration and invasion

Spyrou, Argyris; Roy, Ananya; Xiong, Anqi; Kundu, Soumi et al.

Ingår i Matrix Biology, s. 1-15, 2025

• DOI för Heparan sulfate N-deacetylase/N-sulfotransferase-1 regulates glioblastoma cell migration and invasion

Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap

Ruiz-Moreno, Cristian; Salas, Sergio Marco; Samuelsson, Erik; Minaeva, Mariia et al.

Ingår i Neuro-Oncology, s. 2281-2295, 2025

• DOI för Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap
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Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression

Wicher, Grzegorz; Roy, Ananya; Vaccaro, Alessandra; Vemuri, Kalyani et al.

Ingår i Neuro-Oncology Advances, 2025

• DOI för Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression
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On-chip fabrication of tailored 3D hydrogel scaffolds to model cancer cell invasion and interaction with endothelial cells

Cantoni, Federico; Barbe, Laurent; Roy, Ananya; Wicher, Grzegorz et al.

Ingår i APL Bioengineering, 2024

• DOI för On-chip fabrication of tailored 3D hydrogel scaffolds to model cancer cell invasion and interaction with endothelial cells
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Leveraging base-pair mammalian constraint to understand genetic variation and human disease

Sullivan, Patrick F.; Meadows, Jennifer; Gazal, Steven; Phan, BaDoi N. et al.

Ingår i Science, s. 367-+, 2023

• DOI för Leveraging base-pair mammalian constraint to understand genetic variation and human disease

Using evolutionary constraint to define novel candidate driver genes in medulloblastoma

Roy, Ananya; Sakthikumar, Sharadha; Kozyrev, Sergey V.; Nordin, Jessika et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2023

• DOI för Using evolutionary constraint to define novel candidate driver genes in medulloblastoma
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Mast Cells Limit Ear Swelling Independently of the Chymase Mouse Mast Cell Protease 4 in an MC903-Induced Atopic Dermatitis-Like Mouse Model

Svanberg, Sofie; Li, Zhiqiang; Öhlund, Pontus; Roy, Ananya et al.

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Mast Cells Limit Ear Swelling Independently of the Chymase Mouse Mast Cell Protease 4 in an MC903-Induced Atopic Dermatitis-Like Mouse Model
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Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression

Xiong, Anqi; Roy, Ananya; Spyrou, Argyris; Weishaupt, Holger et al.

Ingår i Cancers, 2020

• DOI för Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression
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Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes

Sakthikumar, Sharadha; Roy, Ananya; Haseeb, Lulu; Pettersson, Mats E. et al.

Ingår i Genome Biology, 2020

• DOI för Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes
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Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Roy, Ananya; Libard, Sylwia; Weishaupt, Holger; Gustavsson, Ida et al.

Ingår i Frontiers in Oncology, 2017

• DOI för Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
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Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression

Roy, Ananya; Attarha, Sanaz; Weishaupt, Holger; Edqvist, Per-Henrik et al.

Ingår i Oncotarget, s. 24815-24827, 2017

• DOI för Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
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Targeting metastasis in mammary carcinoma: functional analysis of serglycin proteoglycan (and the chymase mMCP-4)

Roy, Ananya; Etal, Damla; Hedenqvist, Patricia; Li, Zhiqiang et al.

Ingår i Scandinavian Journal of Immunology, s. 313-313, 2017

Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3 beta expression and inhibition of STAT3 activation

Attarha, Sanaz; Roy, Ananya; Westermark, Bengt; Tchougounova, Elena

Ingår i Cellular Signalling, s. 81-92, 2017

• DOI för Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3 beta expression and inhibition of STAT3 activation

Serglycin proteoglycans limit enteropathy in Trichinella spiralis-infected mice

Roy, Ananya; Sawesi, Osama; Pettersson, Ulrika A.; Dagälv, Anders et al.

Ingår i BMC Immunology, 2016

• DOI för Serglycin proteoglycans limit enteropathy in Trichinella spiralis-infected mice
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Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma

Roy, Ananya; Femel, Julia; Huijbers, Elisabeth J. M.; Spillmann, Dorothe et al.

Ingår i PLOS ONE, 2016

• DOI för Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma
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Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Ingår i Oncotarget, s. 23647-23661, 2015

• DOI för Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
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Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

Roy, Ananya; Ganesh, Goutham; Sippola, Helena; Bolin, Sara et al.

Ingår i Journal of Biological Chemistry, s. 237-250, 2014

• DOI för Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements

Iniguez-Munoz, Sandra; Llinas-Arias, Pere; Ensenyat-Mendez, Miquel; Bedoya-Lopez, Andres F. et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), 2024

• DOI för Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements
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Mast Cells as Sentinels: Role of serglycin and mast cell proteases in infection and inflammation

Roy, Ananya

2012

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Microengineering a cell co-culture platform for glioblastoma cell migration and intravasation studies

Cantoni, Federico; Barbe, Laurent; Roy, Ananya; Wicher, Grzegorz K. et al.