Patrik Lundquist

An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process

Leist, Marcel; Tangianu, Silvia; Affourtit, Femke; Braakhuis, Hedwig et al.

Part of Altex, p. 158-175, 2026

• DOI for An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process
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The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays

Munic Kos, Vesna; Arvidsson McShane, Staffan; Islam, Barira; Nikiforova, Violetta et al.

Part of Environmental Toxicology and Pharmacology, 2025

• DOI for The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays
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Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Part of Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI for Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
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Trust Your Gut: Establishing Confidence in Gastrointestinal Models - An Overview of the State of the Science and Contexts of Use

Debad, Susan; Allen, David; Bandele, Omari; Bishop, Colin et al.

Part of Altex, p. 402-424, 2024

• DOI for Trust Your Gut: Establishing Confidence in Gastrointestinal Models - An Overview of the State of the Science and Contexts of Use
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Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat

Lundquist, Patrik; Khodus, Georgiy; Niu, Zhigao; Thwala, Lungile Nomcebo et al.

Part of ACS Nano, p. 14210-14229, 2022

• DOI for Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
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An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process

Leist, Marcel; Tangianu, Silvia; Affourtit, Femke; Braakhuis, Hedwig et al.

Part of Altex, p. 158-175, 2026

• DOI for An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process
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The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays

Munic Kos, Vesna; Arvidsson McShane, Staffan; Islam, Barira; Nikiforova, Violetta et al.

Part of Environmental Toxicology and Pharmacology, 2025

• DOI for The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays
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Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Part of Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI for Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
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Trust Your Gut: Establishing Confidence in Gastrointestinal Models - An Overview of the State of the Science and Contexts of Use

Debad, Susan; Allen, David; Bandele, Omari; Bishop, Colin et al.

Part of Altex, p. 402-424, 2024

• DOI for Trust Your Gut: Establishing Confidence in Gastrointestinal Models - An Overview of the State of the Science and Contexts of Use
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Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat

Lundquist, Patrik; Khodus, Georgiy; Niu, Zhigao; Thwala, Lungile Nomcebo et al.

Part of ACS Nano, p. 14210-14229, 2022

• DOI for Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
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Global variability analysis of mRNA and protein concentrations across and within human tissues

Wegler, Christine; Ölander, Magnus; Wiśniewski, Jacek R; Lundquist, Patrik et al.

Part of NAR Genomics and Bioinformatics, 2020

• DOI for Global variability analysis of mRNA and protein concentrations across and within human tissues
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A new opening for orally taken peptide drugs

Artursson, Per; Lundquist, Patrik

Part of Nature Biomedical Engineering, p. 12-13, 2020

• DOI for A new opening for orally taken peptide drugs

The stimulation of GLP-1 secretion and delivery of GLP-1 agonists &ITvia&IT nanostructured lipid carriers

Shrestha, Neha; Bouttefeux, Oriane; Vanvarenberg, Kevin; Lundquist, Patrik et al.

Part of Nanoscale, p. 603-613, 2018

• DOI for The stimulation of GLP-1 secretion and delivery of GLP-1 agonists &ITvia&IT nanostructured lipid carriers

A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.

Karlgren, Maria; Simoff, Ivailo; Backlund, Maria; Wegler, Christine et al.

Part of Journal of Pharmaceutical Sciences, p. 2909-2913, 2017

• DOI for A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.

The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition

Ölander, Magnus; Wiśniewski, Jacek R.; Matsson, Pär; Lundquist, Patrik et al.

Part of Journal of Pharmaceutical Sciences, p. 817-827, 2016

• DOI for The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition

The Need for Speed-Kinetic Limits of Drug Transporters

Matsson, Pär X.; Lundquist, Patrik; Artursson, Per

Part of TIPS - Trends in Pharmacological Sciences, p. 243-245, 2016

• DOI for The Need for Speed-Kinetic Limits of Drug Transporters

Addendum to 'Quantifying the impact of transporters on cellular drug permeability'

Matsson, Pär; Fenu, Luca A.; Lundquist, Patrik; Wisniewski, Jacek R. et al.

Part of TIPS - Trends in Pharmacological Sciences, p. 559-559, 2015

• DOI for Addendum to 'Quantifying the impact of transporters on cellular drug permeability'

Quantifying the impact of transporters on cellular drug permeability.

Matsson, Pär; Fenu, Luca A; Lundquist, Patrik; Wiśniewski, Jacek R et al.

Part of TIPS - Trends in Pharmacological Sciences, p. 255-262, 2015

• DOI for Quantifying the impact of transporters on cellular drug permeability.
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Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors

Englund, Gunilla; Lundquist, Patrik; Skogastierna, Cristine; Johansson, Jenny et al.

Part of Drug Metabolism And Disposition, p. 441-447, 2014

• DOI for Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors

Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition

Lundquist, Patrik; Englund, Gunilla; Skogastierna, Cristine; Loof, Johan et al.

Part of Drug Metabolism And Disposition, p. 448-458, 2014

• DOI for Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition

Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model

Lundquist, Patrik; Loof, Johan; Fagerholm, Urban; Sjogren, Ingemo et al.

Part of Drug Metabolism And Disposition, p. 459-468, 2014

• DOI for Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model

The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions

Lundquist, Patrik; Loof, Johan; Sohlenius-Sternbeck, Anna-Karin; Floby, Eva et al.

Part of Drug Metabolism And Disposition, p. 469-480, 2014

• DOI for The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions

The utility of cold-preserved human hepatocytes in studies on cytochrome P450 induction and hepatic drug transport

Juric, Sanja; Lundquist, Patrik; Hu, Yin; Juréus, Anna et al.

Part of Xenobiotica, p. 785-791, 2013

• DOI for The utility of cold-preserved human hepatocytes in studies on cytochrome P450 induction and hepatic drug transport

Global expression variability of proteins across and within human tissues

Wegler, Christine; Ölander, Magnus; Wisniewski, Jacek R; Lundquist, Patrik et al.

Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

Lundquist, Patrik; Artursson, Per

Part of Advanced Drug Delivery Reviews, p. 256-276, 2016

• DOI for Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
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