Patrik Lundquist

Stakeholder Input Towards Further Refinement and Consolidation of the Alternative Safety Profiling Algorithm (ASPA) for Next Generation Risk Assessment (NGRA)

Luijten, Mirjam; Herzler, Matthias; Affourtit, Femke; Allen, Dave et al.

Ingår i Altex, s. 499-509, 2026

• DOI för Stakeholder Input Towards Further Refinement and Consolidation of the Alternative Safety Profiling Algorithm (ASPA) for Next Generation Risk Assessment (NGRA)
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Complex Distribution Phenomena and Plastic Binding of Test Chemicals in Cell Culture Experiments: Exemplification by Tebufenpyrad

Alimohammadi, Mahshid; Khalidi, Hiba; Zgheib, Elias; Holzer, Anna-Katharina et al.

Ingår i International Journal of Molecular Sciences, 2026

• DOI för Complex Distribution Phenomena and Plastic Binding of Test Chemicals in Cell Culture Experiments: Exemplification by Tebufenpyrad
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Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines

Ravi Shankar, Abishek Laxmanan; Irwan, Jenny; Spaenig, Max; Carlier, Maxim et al.

Ingår i Archives of Toxicology, s. 1877-1901, 2026

• DOI för Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines
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An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process

Leist, Marcel; Tangianu, Silvia; Affourtit, Femke; Braakhuis, Hedwig et al.

Ingår i Altex, s. 158-175, 2026

• DOI för An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process
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The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays

Munic Kos, Vesna; Arvidsson McShane, Staffan; Islam, Barira; Nikiforova, Violetta et al.

Ingår i Environmental Toxicology and Pharmacology, 2025

• DOI för The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays
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Stakeholder Input Towards Further Refinement and Consolidation of the Alternative Safety Profiling Algorithm (ASPA) for Next Generation Risk Assessment (NGRA)

Luijten, Mirjam; Herzler, Matthias; Affourtit, Femke; Allen, Dave et al.

Ingår i Altex, s. 499-509, 2026

• DOI för Stakeholder Input Towards Further Refinement and Consolidation of the Alternative Safety Profiling Algorithm (ASPA) for Next Generation Risk Assessment (NGRA)
• Ladda ner fulltext (pdf) av Stakeholder Input Towards Further Refinement and Consolidation of the Alternative Safety Profiling Algorithm (ASPA) for Next Generation Risk Assessment (NGRA)

Complex Distribution Phenomena and Plastic Binding of Test Chemicals in Cell Culture Experiments: Exemplification by Tebufenpyrad

Alimohammadi, Mahshid; Khalidi, Hiba; Zgheib, Elias; Holzer, Anna-Katharina et al.

Ingår i International Journal of Molecular Sciences, 2026

• DOI för Complex Distribution Phenomena and Plastic Binding of Test Chemicals in Cell Culture Experiments: Exemplification by Tebufenpyrad
• Ladda ner fulltext (pdf) av Complex Distribution Phenomena and Plastic Binding of Test Chemicals in Cell Culture Experiments: Exemplification by Tebufenpyrad

Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines

Ravi Shankar, Abishek Laxmanan; Irwan, Jenny; Spaenig, Max; Carlier, Maxim et al.

Ingår i Archives of Toxicology, s. 1877-1901, 2026

• DOI för Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines
• Ladda ner fulltext (pdf) av Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines

An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process

Leist, Marcel; Tangianu, Silvia; Affourtit, Femke; Braakhuis, Hedwig et al.

Ingår i Altex, s. 158-175, 2026

• DOI för An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process
• Ladda ner fulltext (pdf) av An Alternative Safety Profiling Algorithm (ASPA) to Transform Next Generation Risk Assessment into a Structured and Transparent Process

The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays

Munic Kos, Vesna; Arvidsson McShane, Staffan; Islam, Barira; Nikiforova, Violetta et al.

Ingår i Environmental Toxicology and Pharmacology, 2025

• DOI för The intracellular free concentration of endocrine disrupting chemicals enables translation between cell-free and cell-based estrogenic activity assays
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Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Ingår i Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI för Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
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Trust Your Gut: Establishing Confidence in Gastrointestinal Models - An Overview of the State of the Science and Contexts of Use

Debad, Susan; Allen, David; Bandele, Omari; Bishop, Colin et al.

Ingår i Altex, s. 402-424, 2024

• DOI för Trust Your Gut: Establishing Confidence in Gastrointestinal Models - An Overview of the State of the Science and Contexts of Use
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Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat

Lundquist, Patrik; Khodus, Georgiy; Niu, Zhigao; Thwala, Lungile Nomcebo et al.

Ingår i ACS Nano, s. 14210-14229, 2022

• DOI för Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
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Global variability analysis of mRNA and protein concentrations across and within human tissues

Wegler, Christine; Ölander, Magnus; Wiśniewski, Jacek R; Lundquist, Patrik et al.

Ingår i NAR Genomics and Bioinformatics, 2020

• DOI för Global variability analysis of mRNA and protein concentrations across and within human tissues
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A new opening for orally taken peptide drugs

Artursson, Per; Lundquist, Patrik

Ingår i Nature Biomedical Engineering, s. 12-13, 2020

• DOI för A new opening for orally taken peptide drugs

The stimulation of GLP-1 secretion and delivery of GLP-1 agonists &ITvia&IT nanostructured lipid carriers

Shrestha, Neha; Bouttefeux, Oriane; Vanvarenberg, Kevin; Lundquist, Patrik et al.

Ingår i Nanoscale, s. 603-613, 2018

• DOI för The stimulation of GLP-1 secretion and delivery of GLP-1 agonists &ITvia&IT nanostructured lipid carriers

A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.

Karlgren, Maria; Simoff, Ivailo; Backlund, Maria; Wegler, Christine et al.

Ingår i Journal of Pharmaceutical Sciences, s. 2909-2913, 2017

• DOI för A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.

The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition

Ölander, Magnus; Wiśniewski, Jacek R.; Matsson, Pär; Lundquist, Patrik et al.

Ingår i Journal of Pharmaceutical Sciences, s. 817-827, 2016

• DOI för The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition

The Need for Speed-Kinetic Limits of Drug Transporters

Matsson, Pär X.; Lundquist, Patrik; Artursson, Per

Ingår i TIPS - Trends in Pharmacological Sciences, s. 243-245, 2016

• DOI för The Need for Speed-Kinetic Limits of Drug Transporters

Addendum to 'Quantifying the impact of transporters on cellular drug permeability'

Matsson, Pär; Fenu, Luca A.; Lundquist, Patrik; Wisniewski, Jacek R. et al.

Ingår i TIPS - Trends in Pharmacological Sciences, s. 559-559, 2015

• DOI för Addendum to 'Quantifying the impact of transporters on cellular drug permeability'

Quantifying the impact of transporters on cellular drug permeability.

Matsson, Pär; Fenu, Luca A; Lundquist, Patrik; Wiśniewski, Jacek R et al.

Ingår i TIPS - Trends in Pharmacological Sciences, s. 255-262, 2015

• DOI för Quantifying the impact of transporters on cellular drug permeability.
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Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors

Englund, Gunilla; Lundquist, Patrik; Skogastierna, Cristine; Johansson, Jenny et al.

Ingår i Drug Metabolism And Disposition, s. 441-447, 2014

• DOI för Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors

Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition

Lundquist, Patrik; Englund, Gunilla; Skogastierna, Cristine; Loof, Johan et al.

Ingår i Drug Metabolism And Disposition, s. 448-458, 2014

• DOI för Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition

Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model

Lundquist, Patrik; Loof, Johan; Fagerholm, Urban; Sjogren, Ingemo et al.

Ingår i Drug Metabolism And Disposition, s. 459-468, 2014

• DOI för Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model

The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions

Lundquist, Patrik; Loof, Johan; Sohlenius-Sternbeck, Anna-Karin; Floby, Eva et al.

Ingår i Drug Metabolism And Disposition, s. 469-480, 2014

• DOI för The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions

The utility of cold-preserved human hepatocytes in studies on cytochrome P450 induction and hepatic drug transport

Juric, Sanja; Lundquist, Patrik; Hu, Yin; Juréus, Anna et al.

Ingår i Xenobiotica, s. 785-791, 2013

• DOI för The utility of cold-preserved human hepatocytes in studies on cytochrome P450 induction and hepatic drug transport

Global expression variability of proteins across and within human tissues

Wegler, Christine; Ölander, Magnus; Wisniewski, Jacek R; Lundquist, Patrik et al.

Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

Lundquist, Patrik; Artursson, Per

Ingår i Advanced Drug Delivery Reviews, s. 256-276, 2016

• DOI för Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
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