Kailash Singh

Diabetic complications and prospective immunotherapy

Reynolds, Lewis; Luo, Zhengkang; Singh, Kailash

Part of Frontiers in Immunology, 2023

• DOI for Diabetic complications and prospective immunotherapy
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Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes

Luo, Zhengkang; Soläng, Charlotte; Larsson, Rasmus; Singh, Kailash

Part of International Journal of Molecular Sciences, 2022

• DOI for Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes
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Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development

Singh, Kailash; Bricard, Orian; Haughton, Jeason; Björkqvist, Mikaela et al.

Part of Biomolecules, 2022

• DOI for Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development
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Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells

Luo, Zhengkang; Lundin, Sara; Mejia Cordova, Mariela; Hassani, Imane et al.

Part of International Journal of Molecular Sciences, 2021

• DOI for Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells
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Cellular immunological changes in patients with LADA are a mixture of those seen in patients with type 1 and type 2 diabetes

Singh, Kailash; Martinell, Mats; Luo, Zhengkang; Espes, Daniel et al.

Part of Clinical and Experimental Immunology, p. 64-73, 2019

• DOI for Cellular immunological changes in patients with LADA are a mixture of those seen in patients with type 1 and type 2 diabetes
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Increased Interleukin-35 Levels in Patients With Type 1 Diabetes With Remaining C-Peptide

Espes, Daniel; Singh, Kailash; Sandler, Stellan; Carlsson, Per-Ola

Part of Diabetes Care, p. 1090-1095, 2017

• DOI for Increased Interleukin-35 Levels in Patients With Type 1 Diabetes With Remaining C-Peptide

Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naive mice

Singh, Kailash; Hjort, Marcus; Thorvaldson, Lina; Sandler, Stellan

Part of Scientific Reports, p. 7767, 2015

• DOI for Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naive mice
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Interleukin-35 administration counteracts established murine type 1 diabetes - possible involvement of regulatory T cells

Singh, Kailash; Kadesjö, Erik; Lindroos, Julia; Hjort, Marcus et al.

Part of Scientific Reports, 2015

• DOI for Interleukin-35 administration counteracts established murine type 1 diabetes - possible involvement of regulatory T cells
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Assessing the Effectiveness of Interleukin-2 Therapy in Experimental Type 1 Diabetes

Luo, Zhengkang; Mejia Cordova, Mariela; Hamze, Nour; Berggren, Elin et al.

Part of Endocrine, p. 626-637, 2024

• DOI for Assessing the Effectiveness of Interleukin-2 Therapy in Experimental Type 1 Diabetes
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Investigating the effects of radiation, T cell depletion, and bone marrow transplantation on murine gut microbiota

Kreisinger, Jakub; Dooley, James; Singh, Kailash; Cízková, Dagmar et al.

Part of Frontiers in Microbiology, 2024

• DOI for Investigating the effects of radiation, T cell depletion, and bone marrow transplantation on murine gut microbiota
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Diabetic complications and prospective immunotherapy

Reynolds, Lewis; Luo, Zhengkang; Singh, Kailash

Part of Frontiers in Immunology, 2023

• DOI for Diabetic complications and prospective immunotherapy
• Download full text (pdf) of Diabetic complications and prospective immunotherapy

Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes

Luo, Zhengkang; Soläng, Charlotte; Larsson, Rasmus; Singh, Kailash

Part of International Journal of Molecular Sciences, 2022

• DOI for Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes
• Download full text (pdf) of Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes

Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development

Singh, Kailash; Bricard, Orian; Haughton, Jeason; Björkqvist, Mikaela et al.

Part of Biomolecules, 2022

• DOI for Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development
• Download full text (pdf) of Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development

Assessing the Effectiveness of Interleukin-2 Therapy in Experimental Type 1 Diabetes

Luo, Zhengkang; Mejia Cordova, Mariela; Hamze, Nour; Berggren, Elin et al.

Part of Endocrine, p. 626-637, 2024

• DOI for Assessing the Effectiveness of Interleukin-2 Therapy in Experimental Type 1 Diabetes
• Download full text (pdf) of Assessing the Effectiveness of Interleukin-2 Therapy in Experimental Type 1 Diabetes

Investigating the effects of radiation, T cell depletion, and bone marrow transplantation on murine gut microbiota

Kreisinger, Jakub; Dooley, James; Singh, Kailash; Cízková, Dagmar et al.

Part of Frontiers in Microbiology, 2024

• DOI for Investigating the effects of radiation, T cell depletion, and bone marrow transplantation on murine gut microbiota
• Download full text (pdf) of Investigating the effects of radiation, T cell depletion, and bone marrow transplantation on murine gut microbiota

Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes

Luo, Zhengkang; Soläng, Charlotte; Larsson, Rasmus; Singh, Kailash

Part of International Journal of Molecular Sciences, 2022

• DOI for Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes
• Download full text (pdf) of Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes

Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development

Singh, Kailash; Bricard, Orian; Haughton, Jeason; Björkqvist, Mikaela et al.

Part of Biomolecules, 2022

• DOI for Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development
• Download full text (pdf) of Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development

Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells

Luo, Zhengkang; Lundin, Sara; Mejia Cordova, Mariela; Hassani, Imane et al.

Part of International Journal of Molecular Sciences, 2021

• DOI for Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells
• Download full text (pdf) of Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells

Significance of host heparanase in promoting tumor growth and metastasis

Zhang, Gan-Lin; Gutter-Kapon, Lilach; Ilan, Neta; Batool, Tahira et al.

Part of Matrix Biology, p. 25-42, 2020

• DOI for Significance of host heparanase in promoting tumor growth and metastasis

Determination of Regulatory T Cell Subsets in Murine Thymus, Pancreatic Draining Lymph Node and Spleen Using Flow Cytometry

Luo, Zhengkang; Thorvaldson, Lina; Blixt, Martin; Singh, Kailash

Part of Journal of Visualized Experiments, 2019

• DOI for Determination of Regulatory T Cell Subsets in Murine Thymus, Pancreatic Draining Lymph Node and Spleen Using Flow Cytometry

The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors

He, Qi; Li, Xiujuan; Singh, Kailash; Luo, Zhengkang et al.

Part of Scientific Reports, 2019

• DOI for The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors
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Kinetics of immune cell responses in the multiple low dose streptozotocin mouse model of type 1 diabetes

Luo, Zhengkang; Soläng, Charlotte; Mejia Cordova, Mariela; Thorvaldson, Lina et al.

Part of FASEB BioAdvances, p. 538-549, 2019

• DOI for Kinetics of immune cell responses in the multiple low dose streptozotocin mouse model of type 1 diabetes
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Cellular immunological changes in patients with LADA are a mixture of those seen in patients with type 1 and type 2 diabetes

Singh, Kailash; Martinell, Mats; Luo, Zhengkang; Espes, Daniel et al.

Part of Clinical and Experimental Immunology, p. 64-73, 2019

• DOI for Cellular immunological changes in patients with LADA are a mixture of those seen in patients with type 1 and type 2 diabetes
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Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas

Li, Xiujuan; Singh, Kailash; Luo, Zhengkang; Mejia Cordova, Mariela et al.

Part of Oncotarget, p. 18720-18733, 2018

• DOI for Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas
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Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis

Digre, Andreas; Singh, Kailash; Åbrink, Magnus; Reijmers, Rogier M. et al.

Part of Scientific Reports, 2017

• DOI for Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis
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Kinetics of innate immune and regulatory T cells responses in experimental diabetic nephropathy

Luo, Zhengkang; Varli, Sonya; Enström, Emma; Thorvaldson, Lina et al.

Part of Scandinavian Journal of Immunology, p. 304-304, 2017

Kinetics of the innate immune cell responses in experimental Type 1 Diabetes

Mejia Cordova, Mariela; Soläng, Charlotte; Luo, Zhengkang; Blixt, Martin et al.

Part of Scandinavian Journal of Immunology, p. 303-304, 2017

The Increased Circulating Plasma Levels of Vascular Endothelial Growth Factor in Patients with Type 1 Diabetes Do Not Correlate to Metabolic Control

Singh, Kailash; Sandler, Stellan; Espes, Daniel

Part of Journal of Diabetes Research, 2017

• DOI for The Increased Circulating Plasma Levels of Vascular Endothelial Growth Factor in Patients with Type 1 Diabetes Do Not Correlate to Metabolic Control
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Role of regulatory B cells in clinical and experimental type 1 diabetes

Lundin, Sara; Espes, Daniel; Luo, Zhenkang; Blixt, Martin et al.

Part of Scandinavian Journal of Immunology, p. 349-349, 2017

Increased Interleukin-35 Levels in Patients With Type 1 Diabetes With Remaining C-Peptide

Espes, Daniel; Singh, Kailash; Sandler, Stellan; Carlsson, Per-Ola

Part of Diabetes Care, p. 1090-1095, 2017

• DOI for Increased Interleukin-35 Levels in Patients With Type 1 Diabetes With Remaining C-Peptide

Kinetics of the Foxp3(+) cell response in kidney tissue of both autoimmune and non-autoimmune induced hyperglycemia in mice

Varli, Sonya; Thorvaldson, Lina; Sandler, Stellan; Singh, Kailash

Part of European Journal of Immunology, p. 1065-1065, 2016

Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naive mice

Singh, Kailash; Hjort, Marcus; Thorvaldson, Lina; Sandler, Stellan

Part of Scientific Reports, p. 7767, 2015

• DOI for Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naive mice
• Download full text (pdf) of Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naive mice

Interleukin-35 administration counteracts established murine type 1 diabetes - possible involvement of regulatory T cells

Singh, Kailash; Kadesjö, Erik; Lindroos, Julia; Hjort, Marcus et al.

Part of Scientific Reports, 2015

• DOI for Interleukin-35 administration counteracts established murine type 1 diabetes - possible involvement of regulatory T cells
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Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis

Oskarsson, Marie E.; Singh, Kailash; Wang, Jian; Vlodavsky, Israel et al.

Part of Journal of Biological Chemistry, p. 15121-15132, 2015

• DOI for Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis

The Kinetics of Thymic-Derived and Peripherally Induced Regulatory T Cell Response in Early Development of Type 1 Diabetes in a Murine Experimental Model

Singh, Kailash; Lundberg, Marcus; Thorvaldson, Lina; Sandler, Stellan

Part of Scandinavian Journal of Immunology, p. 447-447, 2014

Functional Impairment of Regulatory T Cells in the Early Development of T1D in the MLDSTZ Murine Model

Singh, Kailash; Kadesjo, E.; Lindroos, J.; Eriksson, F. E. et al.

Part of Scandinavian Journal of Immunology, p. 286-286, 2013

Kinetics of regulatory T cells in early development of type 1 diabetes in MLDSTZ induced murine model

Singh, Kailash; Kadesjö, E.; Lindroos, J.; Sandler, Stellan et al.

Part of Immunology, p. 26-26, 2012

Diabetic complications and prospective immunotherapy

Reynolds, Lewis; Luo, Zhengkang; Singh, Kailash

Part of Frontiers in Immunology, 2023

• DOI for Diabetic complications and prospective immunotherapy
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Regulatory T cells in type 1 diabetes: the role of IL-35 in counteracting the disease

Singh, Kailash

2017

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Characterization of Cellular Immunology in LADA Patients

Martinell, Mats; Singh, Kailash; Zhengkang, Luo; Espes, Daniel et al.