Malin Graffner Nordberg

Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii

Graffner-Nordberg, Malin; Kolmodin, Karin; Åqvist, Johan; Queener, Sherry F et al.

Part of European Journal of Pharmaceutical Sciences, p. 43-54, 2004

• DOI for Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii

Design and synthesis of dihydrofolate reductase inhibitors encompassing a bridging ester group. Evaluation in a mouse colitis model

Graffner-Nordberg, Malin; Fyfe, M; Brattsand, R; Mellgard, B et al.

Part of Journal of Medicinal Chemistry, p. 3455-3462, 2003

• DOI for Design and synthesis of dihydrofolate reductase inhibitors encompassing a bridging ester group. Evaluation in a mouse colitis model

Approaches to soft drug analogues of dihydrofolate reductase inhibitors: Design and synthesis

Graffner Nordberg, Malin

2001

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Design, Synthesis, Computational Prediction and Biological Evaluation of Ester Soft Drugs as Inhibitors of Dihydrofolate Reductase from Pneumocystis Carinii

Graffner-Nordberg, Malin; Åqvist, J; Queener, SF; Hallberg, A et al.

Part of Journal of Medicinal Chemistry, p. 2391-2402, 2001

• DOI for Design, Synthesis, Computational Prediction and Biological Evaluation of Ester Soft Drugs as Inhibitors of Dihydrofolate Reductase from Pneumocystis Carinii

Computational predictions of binding affinities to dihydrofolatereductase: synthesis and biological evaluation of methotrexate analogues

Graffner-Nordberg, Malin; Marelius, J; Ohlsson, S; Persson, A et al.

Part of Journal of Medicinal Chemistry, p. 3852-3861, 2000

• DOI for Computational predictions of binding affinities to dihydrofolatereductase: synthesis and biological evaluation of methotrexate analogues

Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii

Graffner-Nordberg, Malin; Kolmodin, Karin; Åqvist, Johan; Queener, Sherry F et al.

Part of European Journal of Pharmaceutical Sciences, p. 43-54, 2004

• DOI for Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii

Design and synthesis of dihydrofolate reductase inhibitors encompassing a bridging ester group. Evaluation in a mouse colitis model

Graffner-Nordberg, Malin; Fyfe, M; Brattsand, R; Mellgard, B et al.

Part of Journal of Medicinal Chemistry, p. 3455-3462, 2003

• DOI for Design and synthesis of dihydrofolate reductase inhibitors encompassing a bridging ester group. Evaluation in a mouse colitis model

Design, Synthesis, Computational Prediction and Biological Evaluation of Ester Soft Drugs as Inhibitors of Dihydrofolate Reductase from Pneumocystis Carinii

Graffner-Nordberg, Malin; Åqvist, J; Queener, SF; Hallberg, A et al.

Part of Journal of Medicinal Chemistry, p. 2391-2402, 2001

• DOI for Design, Synthesis, Computational Prediction and Biological Evaluation of Ester Soft Drugs as Inhibitors of Dihydrofolate Reductase from Pneumocystis Carinii

Computational predictions of binding affinities to dihydrofolatereductase: synthesis and biological evaluation of methotrexate analogues

Graffner-Nordberg, Malin; Marelius, J; Ohlsson, S; Persson, A et al.

Part of Journal of Medicinal Chemistry, p. 3852-3861, 2000

• DOI for Computational predictions of binding affinities to dihydrofolatereductase: synthesis and biological evaluation of methotrexate analogues

Synthesis and enzymatic hydrolysis of esters, constituting simple models of soft drugs

Graffner-Nordberg, Malin; Sjödin, K; Tunek, A; Hallberg, A

Part of Chemical and pharmaceutical bulletin, p. 591, 1998

• DOI for Synthesis and enzymatic hydrolysis of esters, constituting simple models of soft drugs
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Computation of Affinity and Selectivity: Binding of 2,4-Diaminopteridine and 2,4-Diaminoquinazoline Inhibitors to Dihydrofolate Reductases

Marelius, J.; Graffner-Nordberg, Malin; Hansson, T; Hallberg, A et al.

Part of J. Comput.-Aided Mol. Design, p. 119-131, 1998

• DOI for Computation of Affinity and Selectivity: Binding of 2,4-Diaminopteridine and 2,4-Diaminoquinazoline Inhibitors to Dihydrofolate Reductases

Approaches to soft drug analogues of dihydrofolate reductase inhibitors: Design and synthesis

Graffner Nordberg, Malin

2001

• Download full text (pdf) of Approaches to soft drug analogues of dihydrofolate reductase inhibitors: Design and synthesis