Göran Alderborn

The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Tofiq, Maryam; Persson, Ann-Sofie; Lazorova, Lucia; Nordström, Josefina et al.

Part of Powder Technology, 2025

• DOI for The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles
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Effect of drug load on the aerosolisation propensity of binary adhesive mixtures for inhalation

Simonsson, Anna; Bramer, Tobias; Wimbush, Alex; Alderborn, Göran

Part of International Journal of Pharmaceutics, 2024

• DOI for Effect of drug load on the aerosolisation propensity of binary adhesive mixtures for inhalation
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Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. II: predicted relationships

Persson, Ann-Sofie; Alderborn, Göran

Part of Pharmaceutical development and technology (Print), p. 509-519, 2023

• DOI for Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. II: predicted relationships
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Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran; Gråsjö, Johan

Part of European journal of pharmaceutics and biopharmaceutics, p. 1-10, 2022

• DOI for Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness
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Effects of a novel weight-loss combination product containing orlistat and acarbose on obesity: A randomized, placebo-controlled trial

Holmbäck, Ulf; Gruden, Stefan; Litorp, Helena; Willhems, Daniel et al.

Part of Obesity, p. 2222-2232, 2022

• DOI for Effects of a novel weight-loss combination product containing orlistat and acarbose on obesity: A randomized, placebo-controlled trial
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The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Tofiq, Maryam; Persson, Ann-Sofie; Lazorova, Lucia; Nordström, Josefina et al.

Part of Powder Technology, 2025

• DOI for The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles
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Effect of drug load on the aerosolisation propensity of binary adhesive mixtures for inhalation

Simonsson, Anna; Bramer, Tobias; Wimbush, Alex; Alderborn, Göran

Part of International Journal of Pharmaceutics, 2024

• DOI for Effect of drug load on the aerosolisation propensity of binary adhesive mixtures for inhalation
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Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. II: predicted relationships

Persson, Ann-Sofie; Alderborn, Göran

Part of Pharmaceutical development and technology (Print), p. 509-519, 2023

• DOI for Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. II: predicted relationships
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Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran; Gråsjö, Johan

Part of European journal of pharmaceutics and biopharmaceutics, p. 1-10, 2022

• DOI for Effect of fluid velocity and particle size on the hydrodynamic diffusion layer thickness
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Effects of a novel weight-loss combination product containing orlistat and acarbose on obesity: A randomized, placebo-controlled trial

Holmbäck, Ulf; Gruden, Stefan; Litorp, Helena; Willhems, Daniel et al.

Part of Obesity, p. 2222-2232, 2022

• DOI for Effects of a novel weight-loss combination product containing orlistat and acarbose on obesity: A randomized, placebo-controlled trial
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Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. I. Experimental comparison

Persson, Ann-Sofie; Pazesh, Samaneh; Alderborn, Göran

Part of Pharmaceutical development and technology (Print), p. 319-330, 2022

• DOI for Tabletability and compactibility of alpha-lactose monohydrate powders of different particle size. I. Experimental comparison
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Deciphering the role of granule deformation and fragmentation for the tableting performance of some dry granulated powders

Tofiq, Maryam; Nordström, Josefina; Persson, Ann-Sofie; Alderborn, Göran

Part of Powder Technology, 2022

• DOI for Deciphering the role of granule deformation and fragmentation for the tableting performance of some dry granulated powders
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Effect of excipient properties and blend ratio on the compression properties of dry granulated particles prepared from microcrystalline cellulose and lactose

Tofiq, Maryam; Nordström, Josefina; Persson, Ann-Sofie; Alderborn, Göran

Part of Powder Technology, 2022

• DOI for Effect of excipient properties and blend ratio on the compression properties of dry granulated particles prepared from microcrystalline cellulose and lactose
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Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, 2022

• DOI for Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation
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Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities

Andersson, Sara B. E.; Frenning, Göran; Alderborn, Göran

Part of Pharmaceutics, 2021

• DOI for Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities
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Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose.

Grudén, Stefan; Forslund, Anders; Alderborn, Göran; Söderhäll, Arvid et al.

Part of Clinical Pharmacology in Drug Development, p. 1242-1247, 2021

• DOI for Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose.
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On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, 2021

• DOI for On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients
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Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity

Holmbäck, Ulf; Forslund, Anders; Gruden, Stefan; Alderborn, Göran et al.

Part of Obesity Science & Practice, p. 313-323, 2020

• DOI for Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
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Atypical compaction behaviour of disordered lactose explained by a shift in type of compact fracture pattern

Pazesh, Samaneh; Persson, Ann-Sofie; Alderborn, Göran

Part of International Journal of Pharmaceutics, 2019

• DOI for Atypical compaction behaviour of disordered lactose explained by a shift in type of compact fracture pattern
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Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, p. 148-160, 2019

• DOI for Linking carrier morphology to the powder mechanics of adhesive mixtures for dry powder inhalers via a blend-state model
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Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Jonsson, Henrik; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 74-81, 2019

• DOI for Evaluation of bulk compression using a discrete element procedure calibrated with data from triaxial experiments on single particles

Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Jonsson, Henrik; Öhman-Mägi, Caroline; Alderborn, Göran; Isaksson, Per et al.

Part of International Journal of Pharmaceutics, p. 130-137, 2019

• DOI for Crack nucleation and propagation in microcrystalline-cellulose based granules subject to uniaxial and triaxial load

Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Nordström, Josefina; Alderborn, Göran; Frenning, Göran

Part of International Journal of Pharmaceutics, p. 120-131, 2018

• DOI for Compressibility and tablet forming ability of bimodal granule mixtures: Experiments and DEM simulations

Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre et al.

Part of International Journal of Pharmaceutics, p. 143-156, 2018

• DOI for Relationships between surface coverage ratio and powder mechanics of binary adhesive mixtures for dry powder inhalers

Determination of interfacial amorphicity in functional powders

Tejedor, Maria Badal; Nordgren, Niklas; Schuleit, Michael; Pazesh, Samaneh et al.

Part of Abstracts of Papers of the American Chemical Society, 2018

Powder Compression Properties of Paracetamol, Paracetamol Hydrochloride, and Paracetamol Cocrystals and Coformers

Persson, Ann-Sofie; Ahmed, Hamzah; Velaga, Sitaram; Alderborn, Göran

Part of Journal of Pharmaceutical Sciences, p. 1920-1927, 2018

• DOI for Powder Compression Properties of Paracetamol, Paracetamol Hydrochloride, and Paracetamol Cocrystals and Coformers

Effect of milling on the plastic and the elastic stiffness of lactose particles

Pazesh, Samaneh; Persson, Ann-Sofie; Berggren, Jonas; Alderborn, Göran

Part of European Journal of Pharmaceutical Sciences, p. 138-145, 2018

• DOI for Effect of milling on the plastic and the elastic stiffness of lactose particles
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A hybrid approach to predict the relationship between tablet tensile strength and compaction pressure using analytical powder compression

Persson, Ann-Sofie; Alderborn, Göran

Part of European journal of pharmaceutics and biopharmaceutics, p. 28-37, 2018

• DOI for A hybrid approach to predict the relationship between tablet tensile strength and compaction pressure using analytical powder compression
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Milling induced amorphisation and recrystallization of alpha-lactose monohydrate

Tejedor, Maria Badal; Pazesh, Samaneh; Nordgren, Niklas; Schuleit, Michael et al.

Part of International Journal of Pharmaceutics, p. 140-147, 2018

• DOI for Milling induced amorphisation and recrystallization of alpha-lactose monohydrate

Determination of Interfacial Amorphicity in Functional Powders

Tejedor, Maria Badal; Nordgren, Niklas; Schuleit, Michael; Pazesh, Samaneh et al.

Part of Langmuir, p. 920-926, 2017

• DOI for Determination of Interfacial Amorphicity in Functional Powders

Comminution-amorphisation relationships during ball milling of lactose at different milling conditions

Pazesh, Samaneh; Gråsjö, Johan; Berggren, Jonas; Alderborn, Göran

Part of International Journal of Pharmaceutics, p. 215-227, 2017

• DOI for Comminution-amorphisation relationships during ball milling of lactose at different milling conditions
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Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

Persson, Ann-Sofie; Nordström, Josefina; Frenning, Göran; Alderborn, Göran

Part of Chemical engineering research & design, p. 183-191, 2016

• DOI for Compression analysis for assessment of pellet plasticity: Identification of reactant pores and comparison between Heckel, Kawakita, and Adams equations

The Granule Porosity Controls the Loss of Compactibility for Both Dry- and Wet-Processed Cellulose Granules but at Different Rate

Nordström, Josefina; Alderborn, Göran

Part of Journal of Pharmaceutical Sciences, p. 2029-2039, 2015

• DOI for The Granule Porosity Controls the Loss of Compactibility for Both Dry- and Wet-Processed Cellulose Granules but at Different Rate

Inhibition of Recrystallization of Amorphous Lactose in Nanocomposites Formed by Spray-Drying

Hellrup, Joel; Alderborn, Göran; Mahlin, Denny

Part of Journal of Pharmaceutical Sciences, p. 3760-3769, 2015

• DOI for Inhibition of Recrystallization of Amorphous Lactose in Nanocomposites Formed by Spray-Drying

The crystallinity of cellulose controls the physical distribution of sorbed water and the capacity to present water for chemical degradation of a solid drug

Höckerfelt, Mina Heidarian; Alderborn, Göran

Part of International Journal of Pharmaceutics, p. 326-333, 2014

• DOI for The crystallinity of cellulose controls the physical distribution of sorbed water and the capacity to present water for chemical degradation of a solid drug

A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter

Mahmoodi, Foad; Klevan, Ingvild; Nordström, Josefina; Alderborn, Göran et al.

Part of International Journal of Pharmaceutics, p. 295-299, 2013

• DOI for A comparison between two powder compaction parameters of plasticity: The effective medium A parameter and the Heckel 1/K parameter
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Mechanism of Amorphisation of Micro-Particles of Griseofulvin During Powder Flow in a Mixer

Pazesh, Samaneh; Höckerfelt, Mina Heidarian; Berggren, Jonas; Bramer, Tobias et al.

Part of Journal of Pharmaceutical Sciences, p. 4036-4045, 2013

• DOI for Mechanism of Amorphisation of Micro-Particles of Griseofulvin During Powder Flow in a Mixer

A protocol for the classification of powder compression characteristics

Nordstrom, Josefina; Kievan, Ingvild; Alderborn, Göran

Part of European journal of pharmaceutics and biopharmaceutics, p. 209-216, 2012

• DOI for A protocol for the classification of powder compression characteristics

An experimental evaluation of an effective medium based compaction equation

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of European Journal of Pharmaceutical Sciences, p. 49-55, 2012

• DOI for An experimental evaluation of an effective medium based compaction equation
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Effect of degree of methoxylation and particle size on compression properties and compactibility of pectin powders

Salbu, Linda; Bauer-Brandl, Annette; Alderborn, Göran; Tho, Ingunn

Part of Pharmaceutical development and technology (Print), p. 333-343, 2012

• DOI for Effect of degree of methoxylation and particle size on compression properties and compactibility of pectin powders

Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 283-290, 2011

• DOI for Effect of spherical-agglomerate strength on the distribution of force during uniaxial compression
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Degree of compression as a potential process control tool of tablet tensile strength

Nordström, Josefina; Alderborn, Göran

Part of Pharmaceutical development and technology (Print), p. 599-608, 2011

• DOI for Degree of compression as a potential process control tool of tablet tensile strength

Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study

Persson, Ann-Sofie; Alderborn, Göran; Frenning, Göran

Part of European Journal of Pharmaceutical Sciences, p. 199-209, 2011

• DOI for Flowability of surface modified pharmaceutical granules: A comparative experimental and numerical study
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Effect of lubrication on the distribution of force between spherical agglomerates during compression

Mahmoodi, Foad; Alderborn, Göran; Frenning, Göran

Part of Powder Technology, p. 69-74, 2010

• DOI for Effect of lubrication on the distribution of force between spherical agglomerates during compression
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Drug release from compacted single inert matrix agglomerates

Fichtner, Frauke; Frenning, Göran; Alderborn, Göran

Part of Journal of Drug Delivery Science and Technology, p. 273-277, 2007

Effect of preparation method on compactability of paracetamol granules and agglomerates

Fichtner, Frauke; Rasmuson, Åke; Ålander, Eva; Alderborn, Göran

Part of International Journal of Pharmaceutics, p. 148-158, 2007

• DOI for Effect of preparation method on compactability of paracetamol granules and agglomerates

The use of extragranular disintegrants in multiple-unit tablet formulations: effect on compressibility, compactibility and disintegration

Adane, M.; Gebre-Mariam, T; Alderborn, Göran; Frenning, Göran

Part of Journal of drug delivery science and technology, p. 279-284, 2007

The influence of PVP incorporation on moisture-induced surface crystallization of amorphous spray-dried lactose particles

Mahlin, Denny; Berggren, Jonas; Gelius, Ulrik; Engström, Sven et al.

Part of International Journal of Pharmaceutics, p. 78-85, 2006

• DOI for The influence of PVP incorporation on moisture-induced surface crystallization of amorphous spray-dried lactose particles

Conductivity percolation in loosely compacted microcrystalline cellulose: An in situ study by dielectric spectroscopy during densification

Nilsson, Martin; Frenning, Göran; Gråsjö, Johan; Alderborn, Göran et al.

Part of Journal of Physical Chemistry B, p. 20502-20506, 2006

• DOI for Conductivity percolation in loosely compacted microcrystalline cellulose: An in situ study by dielectric spectroscopy during densification

A new method for characterizing the release of drugs from single agglomerates

Frenning, Göran; Fichtner, Frauke; Alderborn, Göran

Part of Chemical Engineering Science, p. 3909-3918, 2005

• DOI for A new method for characterizing the release of drugs from single agglomerates

Evolution of distributions and spatial correlations of single-particle forces and stresses during compression of ductile granular materials.

Frenning, Göran; Alderborn, Göran

Part of Phys Rev E Stat Nonlin Soft Matter Phys, 2005

Particle size distribution and evolution in tablet structure during and after compaction.

Fichtner, Frauke; Rasmuson, Ake; Alderborn, Göran

Part of Int J Pharm, p. 211-25, 2005

Compression behaviour and tablet-forming ability of spray-dried amorphous composite particles.

Berggren, Jonas; Frenning, Göran; Alderborn, Göran

Part of Eur J Pharm Sci, p. 191-200, 2004

Effect of intragranular porosity on compression behaviour of and drug release from reservoir pellets

Tunón, Åsa; Gråsjö, Johan; Alderborn, Göran

Part of European Journal of Pharmaceutical Sciences, p. 333-344, 2003

• DOI for Effect of intragranular porosity on compression behaviour of and drug release from reservoir pellets

Water-induced charge transport in tablets of microcrystalline cellulose of varying density: Dielectric spectroscopy and transient current measurements

Nilsson, Martin; Alderborn, Göran; Strömme, Maria

Part of Chemical Physics, p. 159-165, 2003

• DOI for Water-induced charge transport in tablets of microcrystalline cellulose of varying density: Dielectric spectroscopy and transient current measurements

Tablets and compaction

Alderborn, G

Part of Aulton´s Pharmaceutics - The design and manufacture of medicines. 3rd ed., Churchill Livingstone, Edinburgh, 2007

Effect of pressure drop on blend state-dispersibility relationships of adhesive mixtures for inhalation

Rudén, Jonas; Alderborn, Göran; Frenning, Göran; Thalberg, Kyrre et al.