Infektionsmedicin

Vår forskargrupp inom infektionsmedicin arbetar för att ta fram ny kunskap som kan bidra till bättre och mer individanpassad behandling för framtida patienter. Forskningsområdet omfattar infektioner som orsakas av bakterier, virus och zoonoser (smittsamma sjukdomar som sprids från djur till människor).
Beskrivning av vår forskning
Vi arbetar translationellt och genomför både kliniska studier med patienter och friska frivilliga, djurstudier, laboratoriestudier och analyser av hälsodata och registerdata. Flertalet av forskarna arbetar som infektionsläkare vid Akademiska sjukhuset. Därför utgår projekten från kliniskt viktiga frågeställningar och vi har möjlighet att på ett effektivt sätt kommunicera och implementera resultaten av forskningen i sjukvården.
Mer information finns under respektive gruppmedlem (se nedan).
Gruppmedlemmar
Publikationer
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Ingår i PLOS Digital Health, 2026
- DOI för A natural language processing approach to determine whether streamlined health technology assessment for multi-indication medicines is feasible
- Ladda ner fulltext (pdf) av A natural language processing approach to determine whether streamlined health technology assessment for multi-indication medicines is feasible
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Ingår i Nature Medicine, s. 1351-1361, 2026
- DOI för Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals
- Ladda ner fulltext (pdf) av Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals
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Association between short-term exposure to air pollution and COVID-19: a case-crossover cohort study
Ingår i BMJ Open Respiratory Research, 2026
- DOI för Association between short-term exposure to air pollution and COVID-19: a case-crossover cohort study
- Ladda ner fulltext (pdf) av Association between short-term exposure to air pollution and COVID-19: a case-crossover cohort study
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Ingår i Infectious Diseases, s. 453-458, 2026
- DOI för Chronic norovirus infection in a patient with Good's syndrome resolved after fecal microbiota transplantion and improved nutrional status
- Ladda ner fulltext (pdf) av Chronic norovirus infection in a patient with Good's syndrome resolved after fecal microbiota transplantion and improved nutrional status
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Detection of human antibody responses to tick-borne Neoehrlichia mikurensis
Ingår i Medical Microbiology and Immmunology, 2026
- DOI för Detection of human antibody responses to tick-borne Neoehrlichia mikurensis
- Ladda ner fulltext (pdf) av Detection of human antibody responses to tick-borne Neoehrlichia mikurensis
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Diagnostic value of RT-PCR for detection of tick-borne encephalitis virus RNA in cerebrospinal fluid
Ingår i European Journal of Clinical Microbiology and Infectious Diseases, s. 1133-1140, 2026
- DOI för Diagnostic value of RT-PCR for detection of tick-borne encephalitis virus RNA in cerebrospinal fluid
- Ladda ner fulltext (pdf) av Diagnostic value of RT-PCR for detection of tick-borne encephalitis virus RNA in cerebrospinal fluid
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Ingår i Biomaterials Advances, 2026
- DOI för Direct ink writing of collagen scaffolds functionalized with antimicrobial peptides: A proof-of-concept study for bone tissue engineering
- Ladda ner fulltext (pdf) av Direct ink writing of collagen scaffolds functionalized with antimicrobial peptides: A proof-of-concept study for bone tissue engineering
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Drug stock-outs in HIV, tuberculosis, and malaria programs: a systematic review
Ingår i eClinicalMedicine, 2026
- DOI för Drug stock-outs in HIV, tuberculosis, and malaria programs: a systematic review
- Ladda ner fulltext (pdf) av Drug stock-outs in HIV, tuberculosis, and malaria programs: a systematic review
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Ingår i Cell and Tissue Research, 2026
- DOI för Effects of antibiotics encapsulated in hyaluronic acid hydrogels on different osteogenic cells and bacteria
- Ladda ner fulltext (pdf) av Effects of antibiotics encapsulated in hyaluronic acid hydrogels on different osteogenic cells and bacteria
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Ingår i European journal of drug metabolism and pharmacokinetics, s. 413-420, 2026
- DOI för Estimation of Plasma Meropenem Concentrations in Patients with Severe Infections Using Ultraviolet and Visible Range Spectrophotometry: A Pilot Study
- Ladda ner fulltext (pdf) av Estimation of Plasma Meropenem Concentrations in Patients with Severe Infections Using Ultraviolet and Visible Range Spectrophotometry: A Pilot Study
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Ingår i Infection Prevention in Practice, 2026
- DOI för Experiences of vancomycin-resistant enterococci carriage - varying and insufficient information from healthcare providers and divergent feelings in everyday life: a qualitative study
- Ladda ner fulltext (pdf) av Experiences of vancomycin-resistant enterococci carriage - varying and insufficient information from healthcare providers and divergent feelings in everyday life: a qualitative study
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Ingår i BMC Infectious Diseases, 2026
- DOI för Fatal European subtype tick-borne encephalitis in a fully vaccinated immunocompetent child: a case report with viral sequencing
- Ladda ner fulltext (pdf) av Fatal European subtype tick-borne encephalitis in a fully vaccinated immunocompetent child: a case report with viral sequencing
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Ingår i The Lancet Regional Health - Americas, 2026
- DOI för Genomic epidemiology of a 2023–2024 Oropouche virus disease outbreak in Iquitos, Peru: descriptive analysis of a case control study for acute febrile illness
- Ladda ner fulltext (pdf) av Genomic epidemiology of a 2023–2024 Oropouche virus disease outbreak in Iquitos, Peru: descriptive analysis of a case control study for acute febrile illness
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Ingår i Clinical Microbiology and Infection, s. 560-571, 2026
- DOI för How to perform pharmacokinetic research of antimicrobial drugs in critically ill patients undergoing continuous renal replacement therapy: a scoping review of all relevant pharmacokinetic factors
- Ladda ner fulltext (pdf) av How to perform pharmacokinetic research of antimicrobial drugs in critically ill patients undergoing continuous renal replacement therapy: a scoping review of all relevant pharmacokinetic factors
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Ingår i Acta Anaesthesiologica Scandinavica, 2026
- DOI för Impact of Regional Hepatic Immunosuppression With Budesonide on Bacterial Elimination in Porcine Abdominal Sepsis
- Ladda ner fulltext (pdf) av Impact of Regional Hepatic Immunosuppression With Budesonide on Bacterial Elimination in Porcine Abdominal Sepsis
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Ingår i Intensive Care Medicine Experimental, 2026
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Meeting the 2024 UN General Assembly declaration targets on antimicrobial resistance
Ingår i The Lancet, s. 195-198, 2026
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Ingår i European Journal of Clinical Microbiology and Infectious Diseases, s. 185-196, 2026
- DOI för Multicenter evaluation of the QuickMIC® rapid AST system in clinical practice: impact on turnaround time compared to routine AST systems
- Ladda ner fulltext (pdf) av Multicenter evaluation of the QuickMIC® rapid AST system in clinical practice: impact on turnaround time compared to routine AST systems
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Pre-existing systemic inflammation impairs bacterial clearance in the spleen
Ingår i Intensive Care Medicine Experimental, 2026
- DOI för Pre-existing systemic inflammation impairs bacterial clearance in the spleen
- Ladda ner fulltext (pdf) av Pre-existing systemic inflammation impairs bacterial clearance in the spleen
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Ingår i BMJ Open, 2026
- DOI för Protocols for genomic epidemiology and source attribution of enteric bacteria causing diarrhoeal disease across Africa
- Ladda ner fulltext (pdf) av Protocols for genomic epidemiology and source attribution of enteric bacteria causing diarrhoeal disease across Africa
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Ingår i Frontiers in Cellular and Infection Microbiology, 2026
- DOI för Rapid AST in practice - a workflow analysis of the QuickMIC® rapid AST system at multiple clinical laboratories in Europe
- Ladda ner fulltext (pdf) av Rapid AST in practice - a workflow analysis of the QuickMIC® rapid AST system at multiple clinical laboratories in Europe
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Ingår i PLOS ONE, 2026
- DOI för The wild, wild west of plasmids: First insights into comparative genomics of Borrelia burgdorferi sensu lato
- Ladda ner fulltext (pdf) av The wild, wild west of plasmids: First insights into comparative genomics of Borrelia burgdorferi sensu lato
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Time to rethink Blastocystis in faecal microbiota transplantation
Ingår i Trends in Parasitology, s. 439-441, 2026
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Ingår i Environmental Microbiology Reports, 2026
- DOI för Using Ongoing Wildlife Surveillance Programs to Monitor Antibiotic Resistant Bacteria in the Environment
- Ladda ner fulltext (pdf) av Using Ongoing Wildlife Surveillance Programs to Monitor Antibiotic Resistant Bacteria in the Environment
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Ingår i Cell Reports Methods, s. 100935, 2025
- DOI för A core genome MLST scheme for Borrelia burgdorferi sensu lato improves insights into the evolutionary history of the species complex
- Ladda ner fulltext (pdf) av A core genome MLST scheme for Borrelia burgdorferi sensu lato improves insights into the evolutionary history of the species complex
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A human pan-disease blood atlas of the circulating proteome
Ingår i Science, 2025
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Ingår i Clinical Microbiology and Infection, s. 345-353, 2025
- DOI för A systematic review of antibiotic drug shortages and the strategies employed for managing these shortages
- Ladda ner fulltext (pdf) av A systematic review of antibiotic drug shortages and the strategies employed for managing these shortages
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Ingår i Vaccine, 2025
- DOI för Adverse drug reactions following SARS-CoV-2 vaccination of 3805 healthcare workers cause substantial sick-leave and are correlated to vaccine regimen, age, sex and serological response
- Ladda ner fulltext (pdf) av Adverse drug reactions following SARS-CoV-2 vaccination of 3805 healthcare workers cause substantial sick-leave and are correlated to vaccine regimen, age, sex and serological response
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Ingår i International Journal of Antimicrobial Agents, 2025
- DOI för An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae
- Ladda ner fulltext (pdf) av An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae
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Comprised access to antibiotics d the growing problem of availability and responsible use
Ingår i Clinical Microbiology and Infection, s. 331-332, 2025
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Ingår i Frontiers in Oncology, 2025
- DOI för Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy
- Ladda ner fulltext (pdf) av Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy
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Enteric bacteria from a One Health perspective: fecal indicators and antibiotic resistance
2025
- Ladda ner fulltext 1 (pdf) av Enteric bacteria from a One Health perspective: fecal indicators and antibiotic resistance
- Ladda ner fulltext 2 (pdf) av Enteric bacteria from a One Health perspective: fecal indicators and antibiotic resistance
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Ingår i JAC - Antimicrobial Resistance, 2025
- DOI för Evaluation of ceftazidime/avibactam in combination with colistin against KPC-2-producing Klebsiella pneumoniae in static and dynamic time-kill experiments
- Ladda ner fulltext (pdf) av Evaluation of ceftazidime/avibactam in combination with colistin against KPC-2-producing Klebsiella pneumoniae in static and dynamic time-kill experiments
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Explainability for NLP in Pharmacovigilance: A Study on Adverse Event Report Triage in Swedish
Ingår i Proceedings of the Second Workshop on Patient-Oriented Language Processing (CL4Health), s. 46-68, 2025
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Ingår i Upsala Journal of Medical Sciences, 2025
- DOI för Factors associated with health-related quality of life 1 year after COVID-19: a cross-sectional study in Sweden
- Ladda ner fulltext (pdf) av Factors associated with health-related quality of life 1 year after COVID-19: a cross-sectional study in Sweden
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Ingår i Journal of Medical Microbiology, 2025
- DOI för Genomic insights into extended-spectrum β-lactamase- and plasmid-borne AmpC-producing Escherichia coli transmission between humans and livestock in rural Cambodia
- Ladda ner fulltext (pdf) av Genomic insights into extended-spectrum β-lactamase- and plasmid-borne AmpC-producing Escherichia coli transmission between humans and livestock in rural Cambodia
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Ingår i Science of the Total Environment, 2025
- DOI för Global distribution of antimicrobial resistance genes in Escherichia coli isolated from wild animals using genomes available in public databases
- Ladda ner fulltext (pdf) av Global distribution of antimicrobial resistance genes in Escherichia coli isolated from wild animals using genomes available in public databases
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HDV RNA Assays: Performance characteristics, clinical utility and challenges
Ingår i Hepatology, s. 637-650, 2025
- DOI för HDV RNA Assays: Performance characteristics, clinical utility and challenges
- Ladda ner fulltext (pdf) av HDV RNA Assays: Performance characteristics, clinical utility and challenges
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Heterogeneity and metabolic diversity among Enterococcus species during long-term colonization
Ingår i Microbiology Spectrum, 2025
- DOI för Heterogeneity and metabolic diversity among Enterococcus species during long-term colonization
- Ladda ner fulltext (pdf) av Heterogeneity and metabolic diversity among Enterococcus species during long-term colonization
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Ingår i Scientific Reports, 2025
- DOI för Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock
- Ladda ner fulltext (pdf) av Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock
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Ingår i Clinical Microbiology and Infection, s. 1172-1179, 2025
- DOI för Impact of a smartphone application for appropriate antibiotic prescribing at three tertiary hospitals: an international, multicentre stepped-wedge cluster randomized trial
- Ladda ner fulltext (pdf) av Impact of a smartphone application for appropriate antibiotic prescribing at three tertiary hospitals: an international, multicentre stepped-wedge cluster randomized trial
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Introducing new antibiotics for multidrug-resistant bacteria: obstacles and the way forward
Ingår i Clinical Microbiology and Infection, s. 354-359, 2025
- DOI för Introducing new antibiotics for multidrug-resistant bacteria: obstacles and the way forward
- Ladda ner fulltext (pdf) av Introducing new antibiotics for multidrug-resistant bacteria: obstacles and the way forward
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Ingår i Clinical Microbiology and Infection, s. 871-872, 2025
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Ingår i BMC Veterinary Research, 2025
- DOI för Isolation, characterization and phylogenetic analyses of avian influenza A (H9N2) viruses isolated from poultry between 2019 and 2023 in Egypt
- Ladda ner fulltext (pdf) av Isolation, characterization and phylogenetic analyses of avian influenza A (H9N2) viruses isolated from poultry between 2019 and 2023 in Egypt
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Low frequency of N-methyl-D-aspartate receptor autoimmunity in tick-borne encephalitis
Ingår i PLOS ONE, 2025
- DOI för Low frequency of N-methyl-D-aspartate receptor autoimmunity in tick-borne encephalitis
- Ladda ner fulltext (pdf) av Low frequency of N-methyl-D-aspartate receptor autoimmunity in tick-borne encephalitis
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Ingår i Scientific Reports, 2025
- DOI för Maximum lifespan and brain size in mammals are associated with gene family size expansion related to immune system functions
- Ladda ner fulltext (pdf) av Maximum lifespan and brain size in mammals are associated with gene family size expansion related to immune system functions
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Ingår i International Journal of Clinical Pharmacy, s. 178-186, 2025
- DOI för Model-informed precision dosing of vancomycin in clinical practice: an intervention development study
- Ladda ner fulltext (pdf) av Model-informed precision dosing of vancomycin in clinical practice: an intervention development study
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Mortality in epilepsy following brain infections in adults: A register-based population-wide study
Ingår i Seizure, s. 180-184, 2025
- DOI för Mortality in epilepsy following brain infections in adults: A register-based population-wide study
- Ladda ner fulltext (pdf) av Mortality in epilepsy following brain infections in adults: A register-based population-wide study
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Ingår i The Lancet Microbe, 2025
- DOI för Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study
- Ladda ner fulltext (pdf) av Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study
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Ingår i Clinical Infectious Diseases, s. 593-601, 2025