Infektionsmedicin

Vår forskargrupp inom infektionsmedicin arbetar för att ta fram ny kunskap som kan bidra till bättre och mer individanpassad behandling för framtida patienter. Forskningsområdet omfattar infektioner som orsakas av bakterier, virus och zoonoser (smittsamma sjukdomar som sprids från djur till människor).
Beskrivning av vår forskning
Vi arbetar translationellt och genomför både kliniska studier med patienter och friska frivilliga, djurstudier, laboratoriestudier och analyser av hälsodata och registerdata. Flertalet av forskarna arbetar som infektionsläkare vid Akademiska sjukhuset. Därför utgår projekten från kliniskt viktiga frågeställningar och vi har möjlighet att på ett effektivt sätt kommunicera och implementera resultaten av forskningen i sjukvården.
Mer information finns under respektive gruppmedlem (se nedan).
Gruppmedlemmar
Publikationer
Ingår i Cell Reports Methods, s. 100935, 2025
- DOI för A core genome MLST scheme for Borrelia burgdorferi sensu lato improves insights into the evolutionary history of the species complex
- Ladda ner fulltext (pdf) av A core genome MLST scheme for Borrelia burgdorferi sensu lato improves insights into the evolutionary history of the species complex
Ingår i Clinical Microbiology and Infection, s. 345-353, 2025
- DOI för A systematic review of antibiotic drug shortages and the strategies employed for managing these shortages
- Ladda ner fulltext (pdf) av A systematic review of antibiotic drug shortages and the strategies employed for managing these shortages
Ingår i Vaccine, 2025
- DOI för Adverse drug reactions following SARS-CoV-2 vaccination of 3805 healthcare workers cause substantial sick-leave and are correlated to vaccine regimen, age, sex and serological response
- Ladda ner fulltext (pdf) av Adverse drug reactions following SARS-CoV-2 vaccination of 3805 healthcare workers cause substantial sick-leave and are correlated to vaccine regimen, age, sex and serological response
Ingår i International Journal of Antimicrobial Agents, 2025
- DOI för An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae
- Ladda ner fulltext (pdf) av An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae
Comprised access to antibiotics d the growing problem of availability and responsible use
Ingår i Clinical Microbiology and Infection, s. 331-332, 2025
Ingår i Frontiers in Oncology, 2025
- DOI för Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy
- Ladda ner fulltext (pdf) av Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy
Enteric bacteria from a One Health perspective: fecal indicators and antibiotic resistance
2025
- Ladda ner fulltext 1 (pdf) av Enteric bacteria from a One Health perspective: fecal indicators and antibiotic resistance
- Ladda ner fulltext 2 (pdf) av Enteric bacteria from a One Health perspective: fecal indicators and antibiotic resistance
Ingår i JAC - Antimicrobial Resistance, 2025
- DOI för Evaluation of ceftazidime/avibactam in combination with colistin against KPC-2-producing Klebsiella pneumoniae in static and dynamic time-kill experiments
- Ladda ner fulltext (pdf) av Evaluation of ceftazidime/avibactam in combination with colistin against KPC-2-producing Klebsiella pneumoniae in static and dynamic time-kill experiments
Ingår i Journal of Medical Microbiology, 2025
- DOI för Genomic insights into extended-spectrum β-lactamase- and plasmid-borne AmpC-producing Escherichia coli transmission between humans and livestock in rural Cambodia
- Ladda ner fulltext (pdf) av Genomic insights into extended-spectrum β-lactamase- and plasmid-borne AmpC-producing Escherichia coli transmission between humans and livestock in rural Cambodia
Ingår i Science of the Total Environment, 2025
- DOI för Global distribution of antimicrobial resistance genes in Escherichia coli isolated from wild animals using genomes available in public databases
- Ladda ner fulltext (pdf) av Global distribution of antimicrobial resistance genes in Escherichia coli isolated from wild animals using genomes available in public databases
Heterogeneity and metabolic diversity among Enterococcus species during long-term colonization
Ingår i Microbiology Spectrum, 2025
- DOI för Heterogeneity and metabolic diversity among Enterococcus species during long-term colonization
- Ladda ner fulltext (pdf) av Heterogeneity and metabolic diversity among Enterococcus species during long-term colonization
Ingår i Scientific Reports, 2025
- DOI för Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock
- Ladda ner fulltext (pdf) av Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock
Ingår i Clinical Microbiology and Infection, s. 1172-1179, 2025
- DOI för Impact of a smartphone application for appropriate antibiotic prescribing at three tertiary hospitals: an international, multicentre stepped-wedge cluster randomized trial
- Ladda ner fulltext (pdf) av Impact of a smartphone application for appropriate antibiotic prescribing at three tertiary hospitals: an international, multicentre stepped-wedge cluster randomized trial
Introducing new antibiotics for multidrug-resistant bacteria: obstacles and the way forward
Ingår i Clinical Microbiology and Infection, s. 354-359, 2025
- DOI för Introducing new antibiotics for multidrug-resistant bacteria: obstacles and the way forward
- Ladda ner fulltext (pdf) av Introducing new antibiotics for multidrug-resistant bacteria: obstacles and the way forward
Ingår i Clinical Microbiology and Infection, s. 871-872, 2025
Ingår i BMC Veterinary Research, 2025
- DOI för Isolation, characterization and phylogenetic analyses of avian influenza A (H9N2) viruses isolated from poultry between 2019 and 2023 in Egypt
- Ladda ner fulltext (pdf) av Isolation, characterization and phylogenetic analyses of avian influenza A (H9N2) viruses isolated from poultry between 2019 and 2023 in Egypt
Low frequency of N-methyl-D-aspartate receptor autoimmunity in tick-borne encephalitis
Ingår i PLOS ONE, 2025
- DOI för Low frequency of N-methyl-D-aspartate receptor autoimmunity in tick-borne encephalitis
- Ladda ner fulltext (pdf) av Low frequency of N-methyl-D-aspartate receptor autoimmunity in tick-borne encephalitis
Ingår i Scientific Reports, 2025
- DOI för Maximum lifespan and brain size in mammals are associated with gene family size expansion related to immune system functions
- Ladda ner fulltext (pdf) av Maximum lifespan and brain size in mammals are associated with gene family size expansion related to immune system functions
Ingår i International Journal of Clinical Pharmacy, s. 178-186, 2025
- DOI för Model-informed precision dosing of vancomycin in clinical practice: an intervention development study
- Ladda ner fulltext (pdf) av Model-informed precision dosing of vancomycin in clinical practice: an intervention development study
Mortality in epilepsy following brain infections in adults: A register-based population-wide study
Ingår i Seizure, s. 180-184, 2025
- DOI för Mortality in epilepsy following brain infections in adults: A register-based population-wide study
- Ladda ner fulltext (pdf) av Mortality in epilepsy following brain infections in adults: A register-based population-wide study
Ingår i One Health, 2025
- DOI för Regulations, biosecurity measures, and impact of COVID-19: A comprehensive mixed method study in traditional wet and live animal markets in Bangladesh
- Ladda ner fulltext (pdf) av Regulations, biosecurity measures, and impact of COVID-19: A comprehensive mixed method study in traditional wet and live animal markets in Bangladesh
Ingår i Intensive Care Medicine Experimental, 2025
- DOI för Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
- Ladda ner fulltext (pdf) av Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
Ingår i European Journal of Public Health, s. 752-759, 2025
- DOI för Sexually transmitted infections among pre-exposure prophylaxis users in a Swedish multi-centre cohort
- Ladda ner fulltext (pdf) av Sexually transmitted infections among pre-exposure prophylaxis users in a Swedish multi-centre cohort
Ingår i mBio, 2025
- DOI för Sharing of cmeRABC alleles between C. coli and C. jejuni associated with extensive drug resistance in Campylobacter isolates from infants and poultry in the Peruvian Amazon
- Ladda ner fulltext (pdf) av Sharing of cmeRABC alleles between C. coli and C. jejuni associated with extensive drug resistance in Campylobacter isolates from infants and poultry in the Peruvian Amazon
Ingår i Journal of Antimicrobial Chemotherapy, s. 876-884, 2025
- DOI för Short, extended and continuous infusion of β-lactams: predicted impact on target attainment and risk for toxicity in an ICU patient cohort
- Ladda ner fulltext (pdf) av Short, extended and continuous infusion of β-lactams: predicted impact on target attainment and risk for toxicity in an ICU patient cohort
Ingår i International Journal of Antimicrobial Agents, 2025
- DOI för Susceptibility to new antibiotics and genetic characterisation of carbapenemase-producing Enterobacterales: low activity of cefiderocol against NDM-producing isolates
- Ladda ner fulltext (pdf) av Susceptibility to new antibiotics and genetic characterisation of carbapenemase-producing Enterobacterales: low activity of cefiderocol against NDM-producing isolates
Ingår i Next Research, 2025
- DOI för Temporal and spatial variation of third-generation cephalosporin-resistant and ESBL-producing Escherichia coli in a Swedish urban water system
- Ladda ner fulltext (pdf) av Temporal and spatial variation of third-generation cephalosporin-resistant and ESBL-producing Escherichia coli in a Swedish urban water system
Ingår i The Lancet - Infectious diseases, 2025
Ingår i Asian Pacific Journal of Tropical Medicine, 2025
Ingår i Scientific Reports, 2025
- DOI för Utilizing gentamicin concentrations to estimate glomerular filtration rate in intensive care unit patients
- Ladda ner fulltext (pdf) av Utilizing gentamicin concentrations to estimate glomerular filtration rate in intensive care unit patients
Validation of an Optimised Method for Quantitative Detection of Hepatitis E Virus in Pork Sausage
Ingår i Food and Environmnetal Virology, 2025
- DOI för Validation of an Optimised Method for Quantitative Detection of Hepatitis E Virus in Pork Sausage
- Ladda ner fulltext (pdf) av Validation of an Optimised Method for Quantitative Detection of Hepatitis E Virus in Pork Sausage
Ingår i Journal of Clinical Microbiology, 2024
- DOI för A multicenter evaluation of a novel microfluidic rapid AST assay for Gram-negative bloodstream infections
- Ladda ner fulltext (pdf) av A multicenter evaluation of a novel microfluidic rapid AST assay for Gram-negative bloodstream infections
Ingår i Clinical Pharmacology and Therapeutics, s. 871-880, 2024
- DOI för A Natural Language Processing Approach towards Harmonized Communication of Uncertainties Identified during the European Medicine Authorization Process
- Ladda ner fulltext (pdf) av A Natural Language Processing Approach towards Harmonized Communication of Uncertainties Identified during the European Medicine Authorization Process
2024
Bacteriuria and antibiotic use during the third wave of COVID-19 intensive care in Sweden
Ingår i Infectious Diseases, s. 284-293, 2024
- DOI för Bacteriuria and antibiotic use during the third wave of COVID-19 intensive care in Sweden
- Ladda ner fulltext (pdf) av Bacteriuria and antibiotic use during the third wave of COVID-19 intensive care in Sweden
2024
Ingår i Clinical Infectious Diseases, s. 787-794, 2024
- DOI för Consensus Definitions of Cytomegalovirus (CMV) Infection and Disease in Transplant Patients Including Resistant and Refractory CMV for Use in Clinical Trials: 2024 Update From the Transplant Associated Virus Infections Forum
- Ladda ner fulltext (pdf) av Consensus Definitions of Cytomegalovirus (CMV) Infection and Disease in Transplant Patients Including Resistant and Refractory CMV for Use in Clinical Trials: 2024 Update From the Transplant Associated Virus Infections Forum
Ingår i Infectious Diseases, s. 521-530, 2024
- DOI för Diagnosis of external ventricular drainage related infections with real-time 16S PCR and third-generation 16S sequencing
- Ladda ner fulltext (pdf) av Diagnosis of external ventricular drainage related infections with real-time 16S PCR and third-generation 16S sequencing
Ingår i International Journal of Environmental Research and Public Health, 2024
Ingår i mBio, 2024
- DOI för High-throughput phenotype-to-genotype testing of meningococcal carriage and disease isolates detects genetic determinants of disease-relevant phenotypic traits
- Ladda ner fulltext (pdf) av High-throughput phenotype-to-genotype testing of meningococcal carriage and disease isolates detects genetic determinants of disease-relevant phenotypic traits
Ingår i Antimicrobial Agents and Chemotherapy, s. 1-18, 2024
- DOI för Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
- Ladda ner fulltext (pdf) av Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
2024
Ingår i Antimicrobial Agents and Chemotherapy, 2024
- DOI för Impact of porin deficiency on the synergistic potential of colistin in combination with β-lactam/β-lactamase inhibitors against ESBL- and carbapenemase-producing Klebsiella pneumoniae
- Ladda ner fulltext (pdf) av Impact of porin deficiency on the synergistic potential of colistin in combination with β-lactam/β-lactamase inhibitors against ESBL- and carbapenemase-producing Klebsiella pneumoniae
Ingår i Infectious Diseases, s. 110-115, 2024
- DOI för Influenza-associated invasive aspergillosis in patients admitted to the intensive care unit in Sweden: a prospective multicentre cohort study
- Ladda ner fulltext (pdf) av Influenza-associated invasive aspergillosis in patients admitted to the intensive care unit in Sweden: a prospective multicentre cohort study
2024
Ingår i BMC Public Health, 2024
- DOI för Knowledge gaps related to HIV and condom use for preventing pregnancy: a cross-sectional study among migrants in Sweden
- Ladda ner fulltext (pdf) av Knowledge gaps related to HIV and condom use for preventing pregnancy: a cross-sectional study among migrants in Sweden
Ingår i Upsala Journal of Medical Sciences, 2024
- DOI för Lung function at 1-year follow-up in patients with persistent dyspnea after mild COVID-19: comparisons with moderate and critical COVID-19
- Ladda ner fulltext (pdf) av Lung function at 1-year follow-up in patients with persistent dyspnea after mild COVID-19: comparisons with moderate and critical COVID-19
Management of cytomegalovirus infections - Swedish recommendations 2023
Ingår i Infectious Diseases, s. 907-917, 2024
Ingår i Microbiology Spectrum, s. 1-14, 2024
- DOI för Molecular characteristics, fitness, and virulence of high-risk and non-high-risk clones of carbapenemase-producing Klebsiella pneumoniae
- Ladda ner fulltext (pdf) av Molecular characteristics, fitness, and virulence of high-risk and non-high-risk clones of carbapenemase-producing Klebsiella pneumoniae
Ingår i Drug Safety, s. 173-182, 2024
- DOI för Optimizing Signal Management in a Vaccine Adverse Event Reporting System: A Proof-of-Concept with COVID-19 Vaccines Using Signs, Symptoms, and Natural Language Processing
- Ladda ner fulltext (pdf) av Optimizing Signal Management in a Vaccine Adverse Event Reporting System: A Proof-of-Concept with COVID-19 Vaccines Using Signs, Symptoms, and Natural Language Processing