Jonas Eriksson

A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Rokka, Johanna; Nordeman, Patrik; Bergman, Sara; Eriksson, Jonas

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 447-455, 2021

• DOI för A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media
• Ladda ner fulltext (pdf) av A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

The development of ¹¹C-carbonylation chemistry: A systematic view

Eriksson, Jonas; Antoni, Gunnar; Långström, Bengt; Itsenko, Oleksiy

Ingår i Nuclear Medicine and Biology, s. 115-137, 2021

• DOI för The development of ¹¹C-carbonylation chemistry: A systematic view
• Ladda ner fulltext (pdf) av The development of ¹¹C-carbonylation chemistry: A systematic view

Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Syvänen, Stina; Fang, Xiaotian T.; Faresjö, Rebecca; Rokka, Johanna et al.

Ingår i ACS Chemical Neuroscience, s. 4460-4468, 2020

• DOI för Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain
• Ladda ner fulltext (pdf) av Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation

Bergman, Sara; Brandt, Peter; Nordeman, Patrik; Larhed, Mats et al.

Ingår i Molecules, 2017

• DOI för Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation
• Ladda ner fulltext (pdf) av Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation

Low-Pressure Radical C-11-Aminocarbonylation of Alkyl Iodides through Thermal Initiation

Chow, Shiao Y.; Odell, Luke R.; Eriksson, Jonas

Ingår i European Journal of Organic Chemistry, s. 5980-5989, 2016

• DOI för Low-Pressure Radical C-11-Aminocarbonylation of Alkyl Iodides through Thermal Initiation

Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm

Chiotis, Konstantinos; Saint-Aubert, Laure; Savitcheva, Irina; Jelic, Vesna et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 1686-1699, 2016

• DOI för Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm
• Ladda ner fulltext (pdf) av Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm

Transition metal mediated synthesis using [11C]CO at low pressure - a simplified method for 11C-carbonylation

Eriksson, Jonas; van den Hoek, Johan; Windhorst, Albert D.

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 223-228, 2012

• DOI för Transition metal mediated synthesis using [11C]CO at low pressure - a simplified method for 11C-carbonylation

Pretargeted brain PET imaging reveals amyloid-β pathology using a TCO-modified antibody and a fluorine-18-labeled tetrazine

Lopes van den Broek, Sara; Eriksson, Jonas; Yang, Qiaojun; Bucher, Nadja M. et al.

Ingår i Translational Neurodegeneration, 2025

• DOI för Pretargeted brain PET imaging reveals amyloid-β pathology using a TCO-modified antibody and a fluorine-18-labeled tetrazine
• Ladda ner fulltext (pdf) av Pretargeted brain PET imaging reveals amyloid-β pathology using a TCO-modified antibody and a fluorine-18-labeled tetrazine

Fluorine-18 ImmunoPET Imaging of Antibody Brain Kinetics and Amyloid-Beta Pathology

Schlein, Eva; Lopes van den Broek, Sara; Dallas, Tiffany; Andersson, Ken G. et al.

Ingår i ACS Pharmacology & Translational Science, s. 2804-2813, 2025

• DOI för Fluorine-18 ImmunoPET Imaging of Antibody Brain Kinetics and Amyloid-Beta Pathology
• Ladda ner fulltext (pdf) av Fluorine-18 ImmunoPET Imaging of Antibody Brain Kinetics and Amyloid-Beta Pathology

PET imaging of platelet derived growth factor receptor β in lung fibrosis

Wegrzyniak, Olivia; Lechi, Francesco; Rokka, Johanna; Mitran, Bogdan et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för PET imaging of platelet derived growth factor receptor β in lung fibrosis
• Ladda ner fulltext (pdf) av PET imaging of platelet derived growth factor receptor β in lung fibrosis

Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Kanellopoulos, Panagiotis; Lundmark, Fanny; Abouzayed, Ayman; Balestri, Lorenzo Jacopo Ilic et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography
• Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

PET tracers beyond [18F]FDG: Chapter 5: [11C]PE2I & [18F]FE-PE2I

Crnic Bojkovic, Tea; Sigfridsson, Jonathan; Stepanov, Vladimir; Eriksson, Jonas et al.

Ingår i EANM Technologists’ Guide, 2024

• DOI för PET tracers beyond [18F]FDG: Chapter 5: [11C]PE2I & [18F]FE-PE2I

Pretargeted brain PET imaging reveals amyloid-β pathology using a TCO-modified antibody and a fluorine-18-labeled tetrazine

Lopes van den Broek, Sara; Eriksson, Jonas; Yang, Qiaojun; Bucher, Nadja M. et al.

Ingår i Translational Neurodegeneration, 2025

• DOI för Pretargeted brain PET imaging reveals amyloid-β pathology using a TCO-modified antibody and a fluorine-18-labeled tetrazine
• Ladda ner fulltext (pdf) av Pretargeted brain PET imaging reveals amyloid-β pathology using a TCO-modified antibody and a fluorine-18-labeled tetrazine

Fluorine-18 ImmunoPET Imaging of Antibody Brain Kinetics and Amyloid-Beta Pathology

Schlein, Eva; Lopes van den Broek, Sara; Dallas, Tiffany; Andersson, Ken G. et al.

Ingår i ACS Pharmacology & Translational Science, s. 2804-2813, 2025

• DOI för Fluorine-18 ImmunoPET Imaging of Antibody Brain Kinetics and Amyloid-Beta Pathology
• Ladda ner fulltext (pdf) av Fluorine-18 ImmunoPET Imaging of Antibody Brain Kinetics and Amyloid-Beta Pathology

PET imaging of platelet derived growth factor receptor β in lung fibrosis

Wegrzyniak, Olivia; Lechi, Francesco; Rokka, Johanna; Mitran, Bogdan et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för PET imaging of platelet derived growth factor receptor β in lung fibrosis
• Ladda ner fulltext (pdf) av PET imaging of platelet derived growth factor receptor β in lung fibrosis

Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Kanellopoulos, Panagiotis; Lundmark, Fanny; Abouzayed, Ayman; Balestri, Lorenzo Jacopo Ilic et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography
• Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule

Wegrzyniak, Olivia; Lechi, Francesco; Mitran, Bogdan; Cheung, Pierre et al.

Ingår i iScience, 2024

• DOI för Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule
• Ladda ner fulltext (pdf) av Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule

Optimized method for fluorine-18 radiolabeling of Affibody molecules using RESCA

Lechi, Francesco; Eriksson, Jonas; Odell, Luke R.; Wegrzyniak, Olivia et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2024

• DOI för Optimized method for fluorine-18 radiolabeling of Affibody molecules using RESCA
• Ladda ner fulltext (pdf) av Optimized method for fluorine-18 radiolabeling of Affibody molecules using RESCA

Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
• Ladda ner fulltext (pdf) av Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Single domain antibody-scFv conjugate targeting amyloid β and TfR penetrates the blood–brain barrier and interacts with amyloid β

Faresjö, Rebecca; Sjöström, Elisabet O.; Dallas, Tiffany; Berglund, Magnus M. et al.

Ingår i mAbs, 2024

• DOI för Single domain antibody-scFv conjugate targeting amyloid β and TfR penetrates the blood–brain barrier and interacts with amyloid β
• Ladda ner fulltext (pdf) av Single domain antibody-scFv conjugate targeting amyloid β and TfR penetrates the blood–brain barrier and interacts with amyloid β

Synthesis and evaluation of fluorine-18 labelled tetrazines as pre-targeting imaging agents for PET

Schlein, Eva; Rokka, Johanna; Odell, Luke R.; Lopes van den Broek, Sara et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2024

• DOI för Synthesis and evaluation of fluorine-18 labelled tetrazines as pre-targeting imaging agents for PET
• Ladda ner fulltext (pdf) av Synthesis and evaluation of fluorine-18 labelled tetrazines as pre-targeting imaging agents for PET

Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique et al.

Ingår i Acta neuropathologica communications, 2024

• DOI för Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion
• Ladda ner fulltext (pdf) av Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

Wegrzyniak, Olivia; Zhang, Bo; Rokka, Johanna; Rosestedt, Maria et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2023

• DOI för Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β
• Ladda ner fulltext (pdf) av Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

Synaptic density in aging mice measured by [18F]SynVesT-1 PET

Xiong, Mengfei; Roshanbin, Sahar; Sehlin, Dag; Hansen, Hanne D. et al.

Ingår i NeuroImage, 2023

• DOI för Synaptic density in aging mice measured by [18F]SynVesT-1 PET
• Ladda ner fulltext (pdf) av Synaptic density in aging mice measured by [18F]SynVesT-1 PET

[¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Cheung, Pierre; Amin, Mohammad A.; Zhang, Bo; Lechi, Francesco et al.

Ingår i Pharmaceutics, 2023

• DOI för [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44
• Ladda ner fulltext (pdf) av [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.

Cheung, Pierre; Thorngren, Julia; Zhang, Bo; Vasylovska, Svitlana et al.

Ingår i EJNMMI Research, s. 107, 2023

• DOI för Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.
• Ladda ner fulltext (pdf) av Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.

Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody

Roshanbin, Sahar; Julku, Ulrika; Xiong, Mengfei; Eriksson, Jonas et al.

Ingår i Pharmaceutics, 2022

• DOI för Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody
• Ladda ner fulltext (pdf) av Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody

P-119 - Efficient cartridge-based synthesis of a novel [18F]tetrazine for large molecule labelling

Rokka, Johanna; Syvaenen, Stina; Odell, Luke R.; Schlein, Eva et al.

Ingår i Nuclear Medicine and Biology, 2022

• DOI för P-119 - Efficient cartridge-based synthesis of a novel [18F]tetrazine for large molecule labelling

Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging

Schlein, Eva; Syvänen, Stina; Rokka, Johanna; Gustavsson, Tobias et al.

Ingår i Molecular Pharmaceutics, s. 4111-4122, 2022

• DOI för Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging
• Ladda ner fulltext (pdf) av Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging

¹¹C-PiB and ¹²⁴I-antibody PET provide differing estimates of brain amyloid-β after therapeutic intervention

Meier, Silvio R.; Sehlin, Dag; Roshanbin, Sahar; Lim Falk, Victoria et al.

Ingår i Journal of Nuclear Medicine, s. 302-309, 2022

• DOI för ¹¹C-PiB and ¹²⁴I-antibody PET provide differing estimates of brain amyloid-β after therapeutic intervention
• Ladda ner fulltext (pdf) av ¹¹C-PiB and ¹²⁴I-antibody PET provide differing estimates of brain amyloid-β after therapeutic intervention

A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Rokka, Johanna; Nordeman, Patrik; Bergman, Sara; Eriksson, Jonas

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 447-455, 2021

• DOI för A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media
• Ladda ner fulltext (pdf) av A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans

Puuvuori, Emmi; Rokka, Johanna; Carlsson, Per-Ola; Li, Zhanchun et al.

Ingår i Scientific Reports, 2021

• DOI för Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans
• Ladda ner fulltext (pdf) av Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans

In vivo imaging of synaptic density with [C-11]UCB-J PET in two mouse models of neurodegenerative disease

Xiong, Mengfei; Roshanbin, Sahar; Rokka, Johanna; Schlein, Eva et al.

Ingår i NeuroImage, 2021

• DOI för In vivo imaging of synaptic density with [C-11]UCB-J PET in two mouse models of neurodegenerative disease
• Ladda ner fulltext (pdf) av In vivo imaging of synaptic density with [C-11]UCB-J PET in two mouse models of neurodegenerative disease

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Ingår i Biomedicines, 2021

• DOI för PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs
• Ladda ner fulltext (pdf) av PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Syvänen, Stina; Fang, Xiaotian T.; Faresjö, Rebecca; Rokka, Johanna et al.

Ingår i ACS Chemical Neuroscience, s. 4460-4468, 2020

• DOI för Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain
• Ladda ner fulltext (pdf) av Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography.

Jonasson, My; Nordeman, Patrik; Eriksson, Jonas; Wilking, Helena et al.

Ingår i Journal of Neuroscience Research, s. 2208-2218, 2020

• DOI för Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography.
• Ladda ner fulltext (pdf) av Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography.

Optimal timing of tau pathology imaging and automatic extraction of a reference region using dynamic [¹⁸F]THK5317 PET

Jonasson, My; Wall, Anders; Chiotis, Konstantinos; Leuzy, Antoine et al.

Ingår i NeuroImage, 2019

• DOI för Optimal timing of tau pathology imaging and automatic extraction of a reference region using dynamic [¹⁸F]THK5317 PET
• Ladda ner fulltext (pdf) av Optimal timing of tau pathology imaging and automatic extraction of a reference region using dynamic [¹⁸F]THK5317 PET

Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

Rokka, Johanna; Schlein, Eva; Eriksson, Jonas

Ingår i EJNMMI Radiopharmacy and Chemistry, 2019

• DOI för Improved synthesis of SV2A targeting radiotracer [11C]UCB-J
• Ladda ner fulltext (pdf) av Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Ingår i Nuclear Medicine and Biology, s. 1-10, 2019

• DOI för Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass
• Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Synaptic vesicle protein 2A as a potential biomarker in synaptopathies

Heurling, Kerstin; Ashton, Nicholas J; Leuzy, Antoine; Zimmer, Eduardo R et al.

Ingår i Molecular and Cellular Neuroscience, s. 34-42, 2019

• DOI för Synaptic vesicle protein 2A as a potential biomarker in synaptopathies
• Ladda ner fulltext (pdf) av Synaptic vesicle protein 2A as a potential biomarker in synaptopathies

Palladium(0)-Catalyzed Carbonylative Synthesis of N-Acylsulfonamides via Regioselective Acylation

Schembri, Luke S; Eriksson, Jonas; Odell, Luke R.

Ingår i Journal of Organic Chemistry, s. 6970-6981, 2019

• DOI för Palladium(0)-Catalyzed Carbonylative Synthesis of N-Acylsulfonamides via Regioselective Acylation

Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([¹⁸F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression

Verbeek, Joost; Eriksson, Jonas; Syvänen, Stina; Huisman, Marc et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2018

• DOI för Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([¹⁸F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression
• Ladda ner fulltext (pdf) av Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([¹⁸F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression

[F-18]Tetrazine-trans-cyclooctene mediated labelling of antibodies for PET imaging of amyloid-beta

Eriksson, Jonas; Fang, Xiaotian T.; Hultqvist, Greta; Olberg, D. E. et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2018

Automated GMP-production of α-[¹¹ C]methyl-L-tryptophan using a tracer production system (TPS)

Nordeman, Patrik; Yngve, Ulrika; Wilking, Helena; Gustavsson, Sven Åke et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 1106-1109, 2018

• DOI för Automated GMP-production of α-[¹¹ C]methyl-L-tryptophan using a tracer production system (TPS)

Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation

Bergman, Sara; Brandt, Peter; Nordeman, Patrik; Larhed, Mats et al.

Ingår i Molecules, 2017

• DOI för Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation
• Ladda ner fulltext (pdf) av Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation

Low-Pressure Radical 11C-Aminocarbonylation of Alkyl Iodides through Thermal Initiation

Chow, Shiao Y.; Odell, Luke R.; Eriksson, Jonas

Ingår i European Journal of Organic Chemistry, s. 1236-1236, 2017

• DOI för Low-Pressure Radical 11C-Aminocarbonylation of Alkyl Iodides through Thermal Initiation

Synthesis and In Vitro Evaluation of 5-Substituted Benzovesamicol Analogs containing N-Substituted Amides as Potential Positron Emission Tomography Tracers for the Vesicular Acetylcholine Transporter

Roslin, Sara; De Rosa, Maria; Deuther-Conrad, Winnie; Eriksson, Jonas et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 5095-5106, 2017

• DOI för Synthesis and In Vitro Evaluation of 5-Substituted Benzovesamicol Analogs containing N-Substituted Amides as Potential Positron Emission Tomography Tracers for the Vesicular Acetylcholine Transporter

Combined PET and microdialysis for in vivo estimation of drug blood-brain barrier transport and brain unbound concentrations

Gustafsson, Sofia; Eriksson, Jonas; Syvänen, Stina; Eriksson, Olof et al.

Ingår i NeuroImage, s. 177-186, 2017

• DOI för Combined PET and microdialysis for in vivo estimation of drug blood-brain barrier transport and brain unbound concentrations

Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [(11)C]ABP688 PET imaging and ex vivo immunoblotting

Fang, Xiaotian T.; Eriksson, Jonas; Antoni, Gunnar; Yngve, Ulrika et al.

Ingår i Neuropharmacology, s. 293-300, 2017

• DOI för Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [(11)C]ABP688 PET imaging and ex vivo immunoblotting

Parametric Methods for Dynamic (11)C-Phenytoin PET Studies.

Mansor, Syahir; Yaqub, Maqsood; Boellaard, Ronald; Froklage, Femke E et al.

Ingår i Journal of Nuclear Medicine, s. 479-483, 2017

• DOI för Parametric Methods for Dynamic (11)C-Phenytoin PET Studies.

Quantitative assessment of synaptic density using the SV2A ligand C-11-UCBA in humans

Lubberink, Mark; Appel, Lieuwe; Lindskog, K.; Danfors, Torsten et al.

Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 74-74, 2017

Low-Pressure Radical C-11-Aminocarbonylation of Alkyl Iodides through Thermal Initiation

Chow, Shiao Y.; Odell, Luke R.; Eriksson, Jonas

Ingår i European Journal of Organic Chemistry, s. 5980-5989, 2016

• DOI för Low-Pressure Radical C-11-Aminocarbonylation of Alkyl Iodides through Thermal Initiation

Synthesis of ¹¹C-labelled Sulfonyl Carbamates via a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols and [¹¹C]CO

Stevens, Marc; Chow, Chow; Estrada, Sergio; Eriksson, Jonas et al.

Ingår i ChemistryOpen, s. 566-573, 2016

• DOI för Synthesis of ¹¹C-labelled Sulfonyl Carbamates via a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols and [¹¹C]CO
• Ladda ner fulltext (pdf) av Synthesis of ¹¹C-labelled Sulfonyl Carbamates via a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols and [¹¹C]CO

Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm

Chiotis, Konstantinos; Saint-Aubert, Laure; Savitcheva, Irina; Jelic, Vesna et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 1686-1699, 2016

• DOI för Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm
• Ladda ner fulltext (pdf) av Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm

Parametric Binding Images of the TSPO Ligand 18F-DPA-714.

Golla, Sandeep S V; Boellaard, Ronald; Oikonen, Vesa; Hoffmann, Anja et al.

Ingår i Journal of Nuclear Medicine, s. 1543-1547, 2016

• DOI för Parametric Binding Images of the TSPO Ligand 18F-DPA-714.

In vivo (R)-[(11)C]PK11195 PET imaging of 18kDa translocator protein in recent onset psychosis.

van der Doef, Thalia F; de Witte, Lot D; Sutterland, Arjen L; Jobse, Ellen et al.

Ingår i NPJ schizophrenia, 2016

• DOI för In vivo (R)-[(11)C]PK11195 PET imaging of 18kDa translocator protein in recent onset psychosis.

Synthesis of [3-N-11C-methyl]temozolomide via in situ activation of 3-N-hydroxymethyl temozolomide and alkylation with [11C]methyl iodide

Eriksson, Jonas; Van Kooij, Rolph; Schuit, Robert C.; Froklage, Femke E. et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 122-126, 2015

• DOI för Synthesis of [3-N-11C-methyl]temozolomide via in situ activation of 3-N-hydroxymethyl temozolomide and alkylation with [11C]methyl iodide

Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue

Lemoine, Laetitia; Saint-Aubert, Laure; Marutle, Amelia; Antoni, Gunnar et al.

Ingår i Acta neuropathologica communications, 2015

• DOI för Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue
• Ladda ner fulltext (pdf) av Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue

[18F]VM4-037 MicroPET Imaging and Biodistribution of Two In Vivo CAIX-Expressing Tumor Models

Peeters, SarahG.J.A.; Dubois, Ludwig; Lieuwes, NatasjaG.; Laan, Dennis et al.

Ingår i Molecular Imaging and Biology, s. 1-5, 2015

• DOI för [18F]VM4-037 MicroPET Imaging and Biodistribution of Two In Vivo CAIX-Expressing Tumor Models

Quantification of [18F]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients

Golla, Sandeep S V; Boellaard, Ronald; Oikonen, Vesa; Hoffmann, Anja et al.

Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 766-772, 2015

• DOI för Quantification of [18F]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients

A Comparative Study of the Hypoxia PET Tracers [(18)F]HX4, [(18)F]FAZA, and [(18)F]FMISO in a Preclinical Tumor Model.

Peeters, Sarah G J A; Zegers, Catharina M L; Lieuwes, Natasja G; van Elmpt, Wouter et al.

Ingår i International journal of radiation oncology, biology, physics, s. 351-9, 2015

• DOI för A Comparative Study of the Hypoxia PET Tracers [(18)F]HX4, [(18)F]FAZA, and [(18)F]FMISO in a Preclinical Tumor Model.

In Vivo Quantification of Hypoxic and Metabolic Status of NSCLC Tumors Using [18F]HX4 and [18F]FDG-PET/CT Imaging.

Zegers, Catharina M L; van Elmpt, Wouter; Reymen, Bart; Even, Aniek J G et al.

Ingår i Clinical cancer research, s. 6389-6397, 2014

• DOI för In Vivo Quantification of Hypoxic and Metabolic Status of NSCLC Tumors Using [18F]HX4 and [18F]FDG-PET/CT Imaging.

Strategy to develop a MAO-A-resistant 5-hydroxy-L-[beta-C-11]tryptophan isotopologue based on deuterium kinetic isotope effects

Eriksson, Jonas; Åberg, Ola; Selvaraju, Ram K; Antoni, Gunnar et al.

Ingår i EJNMMI Research, 2014

• DOI för Strategy to develop a MAO-A-resistant 5-hydroxy-L-[beta-C-11]tryptophan isotopologue based on deuterium kinetic isotope effects
• Ladda ner fulltext (pdf) av Strategy to develop a MAO-A-resistant 5-hydroxy-L-[beta-C-11]tryptophan isotopologue based on deuterium kinetic isotope effects

Molecular Imaging of Inflammation Reveals Differences Between Drug-Resistant and Drug-Sensitive Animals in a Chronic Model of Temporal Lobe Epilepsy

Potschka, H.; Bogdanovic, R. M.; Syvänen, Stina; Michler, C. et al.

Ingår i Epilepsia, s. 32-32, 2014

• DOI för Molecular Imaging of Inflammation Reveals Differences Between Drug-Resistant and Drug-Sensitive Animals in a Chronic Model of Temporal Lobe Epilepsy

(R)-[(11)C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: Evaluation in a rat epilepsy model

Bogdanović, Renée Marie; Syvänen, Stina; Michler, Christina; Russmann, Vera et al.

Ingår i Neuropharmacology, s. 104-112, 2014

• DOI för (R)-[(11)C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: Evaluation in a rat epilepsy model

Radiation Dose of the P-Glycoprotein Tracer 11C-Laniquidar.

Postnov, Andrey; Froklage, Femke E; van Lingen, Arthur; Reijneveld, Jaap C et al.

Ingår i Journal of Nuclear Medicine, s. 2101-2103, 2013

• DOI för Radiation Dose of the P-Glycoprotein Tracer 11C-Laniquidar.

Hypoxia imaging with [(18)F]HX4 PET in NSCLC patients: Defining optimal imaging parameters.

Zegers, Catharina M L; van Elmpt, Wouter; Wierts, Roel; Reymen, Bart et al.

Ingår i Radiotherapy and Oncology, s. 58-64, 2013

• DOI för Hypoxia imaging with [(18)F]HX4 PET in NSCLC patients: Defining optimal imaging parameters.

[C-11]quinidine and [C-11]laniquidar PET imaging in a chronic rodent epilepsy model: Impact of epilepsy and drug-responsiveness

Syvänen, Stina; Russmann, Vera; Verbeek, Joost; Eriksson, Jonas et al.

Ingår i Nuclear Medicine and Biology, s. 764-775, 2013

• DOI för [C-11]quinidine and [C-11]laniquidar PET imaging in a chronic rodent epilepsy model: Impact of epilepsy and drug-responsiveness

Automation of the 'xenon method' and comparative study on C-11-carbonylation at ambient pressure versus high solvent pressure

Eriksson, Jonas; Åberg, Ola; Antoni, Gunnar

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2013

[(11)C]Sorafenib: Radiosynthesis and preclinical evaluation in tumor-bearing mice of a new TKI-PET tracer.:  

Poot, Alex J; van der Wildt, Berend; Stigter-van Walsum, Marijke; Rongen, Marissa et al.

Ingår i Nuclear Medicine and Biology, s. 488-497, 2013

• DOI för [(11)C]Sorafenib: Radiosynthesis and preclinical evaluation in tumor-bearing mice of a new TKI-PET tracer.:  

Toward Prediction of Efficacy of Chemotherapy: A Proof of Concept Study in Lung Cancer Patients Using [¹¹C]docetaxel and Positron Emission Tomography

van der Veldt, Astrid A. M.; Lubberink, Mark; Mathijssen, Ron H. J.; Loos, Walter J. et al.

Ingår i Clinical Cancer Research, s. 4163-4173, 2013

• DOI för Toward Prediction of Efficacy of Chemotherapy: A Proof of Concept Study in Lung Cancer Patients Using [¹¹C]docetaxel and Positron Emission Tomography

Blood-brain barrier P-glycoprotein function in healthy subjects and Alzheimer's disease patients: effect of polymorphisms in the ABCB1 gene

van Assema, Daniëlle ME; Lubberink, Mark; Rizzu, Patrizia; van Swieten, John C et al.

Ingår i EJNMMI Research, 2012

• DOI för Blood-brain barrier P-glycoprotein function in healthy subjects and Alzheimer's disease patients: effect of polymorphisms in the ABCB1 gene
• Ladda ner fulltext (pdf) av Blood-brain barrier P-glycoprotein function in healthy subjects and Alzheimer's disease patients: effect of polymorphisms in the ABCB1 gene

[11C]phenytoin revisited: synthesis by [11C]CO carbonylation and first evaluation as a P-gp tracer in rats.

Verbeek, Joost; Eriksson, Jonas; Syvänen, Stina; Labots, Maaike et al.

Ingår i EJNMMI Research, s. 36, 2012

• DOI för [11C]phenytoin revisited: synthesis by [11C]CO carbonylation and first evaluation as a P-gp tracer in rats.

[11C]Flumazenil brain uptake is influenced by the blood-brain barrier efflux transporter P-glycoprotein.

Froklage, Femke E; Syvänen, Stina; Hendrikse, N Harry; Huisman, Marc C et al.

Ingår i EJNMMI Research, s. 12, 2012

• DOI för [11C]Flumazenil brain uptake is influenced by the blood-brain barrier efflux transporter P-glycoprotein.

Dual-Phase PET-CT to Differentiate [(18)F]Fluoromethylcholine Uptake in Reactive and Malignant Lymph Nodes in Patients with Prostate Cancer

Oprea-Lager, Daniela E; Vincent, Andrew D; van Moorselaar, Reindert J A; Gerritsen, Winald R et al.

Ingår i PLOS ONE, 2012

• DOI för Dual-Phase PET-CT to Differentiate [(18)F]Fluoromethylcholine Uptake in Reactive and Malignant Lymph Nodes in Patients with Prostate Cancer
• Ladda ner fulltext (pdf) av Dual-Phase PET-CT to Differentiate [(18)F]Fluoromethylcholine Uptake in Reactive and Malignant Lymph Nodes in Patients with Prostate Cancer

Transition metal mediated synthesis using [11C]CO at low pressure - a simplified method for 11C-carbonylation

Eriksson, Jonas; van den Hoek, Johan; Windhorst, Albert D.

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 223-228, 2012

• DOI för Transition metal mediated synthesis using [11C]CO at low pressure - a simplified method for 11C-carbonylation

Altered GABAA Receptor Density and Unaltered Blood-Brain Barrier Transport in a Kainate Model of Epilepsy: An In Vivo Study Using 11C-Flumazenil and PET.

Syvänen, Stina; Labots, Maaike; Tagawa, Yoshihiko; Eriksson, Jonas et al.

Ingår i Journal of Nuclear Medicine, s. 1974-1983, 2012

• DOI för Altered GABAA Receptor Density and Unaltered Blood-Brain Barrier Transport in a Kainate Model of Epilepsy: An In Vivo Study Using 11C-Flumazenil and PET.

Synthesis and preclinical evaluation of [11C]D617, a metabolite of (R)-[11C]verapamil.

Verbeek, Joost; Syvänen, Stina; Schuit, Robert C; Eriksson, Jonas et al.

Ingår i Nuclear Medicine and Biology, s. 530-9, 2012

• DOI för Synthesis and preclinical evaluation of [11C]D617, a metabolite of (R)-[11C]verapamil.

Rapid Decrease in Delivery of Chemotherapy to Tumors after Anti-VEGF Therapy: Implications for Scheduling of Anti-Angiogenic Drugs

van der Veldt, Astrid A. M.; Lubberink, Mark; Bahce, Idris; Walraven, Maudy et al.

Ingår i Cancer Cell, s. 82-91, 2012

• DOI för Rapid Decrease in Delivery of Chemotherapy to Tumors after Anti-VEGF Therapy: Implications for Scheduling of Anti-Angiogenic Drugs

Towards Prediction of Efficacy of Chemotherapy: a Proof of Concept Study in Lung Cancer Patients Using [11C]docetaxel and Positron Emission Tomography

Van der Veldt, A. A.; Lubberink, Mark; Mathijssen, R. H.; Loos, W. J. et al.

Ingår i European Journal of Cancer, s. 75-76, 2012

• DOI för Towards Prediction of Efficacy of Chemotherapy: a Proof of Concept Study in Lung Cancer Patients Using [11C]docetaxel and Positron Emission Tomography

Synthesis of two potential NK₁-receptor ligands using [1-¹¹C]ethyl iodide and [1-¹¹C]propyl iodide and initial PET-imaging

Syvänen, Stina; Eriksson, Jonas; Genchel, Tove; Lindhe, Örjan et al.

Ingår i BMC Medical Imaging, s. 6, 2007

• DOI för Synthesis of two potential NK₁-receptor ligands using [1-¹¹C]ethyl iodide and [1-¹¹C]propyl iodide and initial PET-imaging

Synthesis of [¹¹C]/[¹³C]acrylamides by palladium-mediated carbonylation

Eriksson, Jonas; Åberg, Ola; Långström, Bengt

Ingår i European Journal of Organic Chemistry, s. 455-461, 2007

• DOI för Synthesis of [¹¹C]/[¹³C]acrylamides by palladium-mediated carbonylation

Synthesis of [1-C-11]propyl and [1-C-11]butyl iodide from [C-11]carbon monoxide and their use in alkylation reactions

Eriksson, Jonas; Antoni, Gunnar; Långström, Bengt

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 1105-1116, 2006

• DOI för Synthesis of [1-C-11]propyl and [1-C-11]butyl iodide from [C-11]carbon monoxide and their use in alkylation reactions

[C-11]methyl iodide from [C-11]methane and iodine using a non-thermal plasma method

Eriksson, Jonas; Ulin, Johan; Långström, Bengt

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 1177-1186, 2006

• DOI för [C-11]methyl iodide from [C-11]methane and iodine using a non-thermal plasma method

The Effect of Solvent on the Structure of the Transition State for the SN2 Reaction between Cyanide Ion and Ethyl Chloride in DMSO and THF Probed with Six Different Kinetic Isotope Effects

Fang, Yao-ren; MacMillar, Susanna; Eriksson, Jonas; Kolodziejska-Huben, Magdalena et al.

Ingår i J. Org. Chem, s. 4742-4747, 2006

• DOI för The Effect of Solvent on the Structure of the Transition State for the SN2 Reaction between Cyanide Ion and Ethyl Chloride in DMSO and THF Probed with Six Different Kinetic Isotope Effects

Synthesis of [1-11C]ethyl iodide from carbon monoxide and its application in alkylation reactions

Eriksson, Jonas; Antoni, Gunnar; Långström, Bengt

Ingår i Journal of Labelled Compounds and Radiopharmaceuticals, s. 723-731, 2004

Experimental and Theoretical Multiple Kinetic Isotope Effects for an SN2 Reaction. An Attempt to Determine Transition-State Structure and the Ability of Theoretical Methods to Predict Experimental Kinetic Isotope Effects

Fang, Yao-ren; Gao, Ying; Ryberg, Per; Eriksson, Jonas et al.

Ingår i Chemistry European Journal, s. 2696-2709, 2003

PET tracers beyond [18F]FDG: Chapter 5: [11C]PE2I & [18F]FE-PE2I

Crnic Bojkovic, Tea; Sigfridsson, Jonathan; Stepanov, Vladimir; Eriksson, Jonas et al.

Ingår i EANM Technologists’ Guide, 2024

• DOI för PET tracers beyond [18F]FDG: Chapter 5: [11C]PE2I & [18F]FE-PE2I

PET Imaging in Preclinical Anti-Aβ Drug Development

Syvänen, Stina; Meier, Silvio R.; Roshanbin, Sahar; Xiong, Mengfei et al.

Ingår i Pharmaceutical research, s. 1481-1496, 2022

• DOI för PET Imaging in Preclinical Anti-Aβ Drug Development
• Ladda ner fulltext (pdf) av PET Imaging in Preclinical Anti-Aβ Drug Development

The development of ¹¹C-carbonylation chemistry: A systematic view

Eriksson, Jonas; Antoni, Gunnar; Långström, Bengt; Itsenko, Oleksiy

Ingår i Nuclear Medicine and Biology, s. 115-137, 2021

• DOI för The development of ¹¹C-carbonylation chemistry: A systematic view
• Ladda ner fulltext (pdf) av The development of ¹¹C-carbonylation chemistry: A systematic view

Advances in PET Imaging of P-Glycoprotein Function at the Blood-Brain Barrier.

Syvänen, Stina; Eriksson, Jonas

Ingår i ACS Chemical Neuroscience, s. 225-237, 2013

• DOI för Advances in PET Imaging of P-Glycoprotein Function at the Blood-Brain Barrier.

Synthesis of ¹¹C-labelled Alkyl Iodides: Using Non-thermal Plasma and Palladium-mediated Carbonylation Methods

Eriksson, Jonas

2006

• Ladda ner fulltext (pdf) av Synthesis of ¹¹C-labelled Alkyl Iodides: Using Non-thermal Plasma and Palladium-mediated Carbonylation Methods

Synthesis and initial preclinical evaluation of the CRTH2 antagonist [C-11] MK-7246

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Ingår i Journal of Labelled Compounds and Pharmaceuticals, 2019

Journal of Labelled Compounds and Pharmaceuticals: Neurosciences session

Rokka, Johanna; Fang, Xiaotian T.; Hultqvist, Greta; Faresjö, Rebecca et al.

Ingår i ISRS 2019, 2019

• DOI för Journal of Labelled Compounds and Pharmaceuticals: Neurosciences session

Tracer kinetic analysis of (S)-[F-18]THK5117 as a PET tracer for tau pathology

Lubberink, Mark; Jonasson, My; Wall, Anders; Chiotis, Konstantinos et al.

2015

Transgenic mice harboring the Uppsala APP mutation display altered APP processing and accelerated Aβ42 pathology with distinct structural features

Pagnon de la Vega, María; Syvänen, Stina; Hooley, Monique; Giedraitis, Vilmantas et al.

[1-11C]Ethyl iodide and [1-11C]propyl iodide in the synthesis of two potential NK1-receptor ligands and initial PET-imaging

Syvänen, Stina; Eriksson, Jonas; Genchel, Tove; Lindhe, Örjan et al.

Single domain antibody conjugated to Aβ-binding scFv penetrates BBB via TfR to interact with Aβ

Faresjö, Rebecca; O Sjöström, Elisabet; Berglund, Magnus; Eriksson, Jonas et al.

Synaptic density in aging mice measured by [¹⁸F]SynVesT-1 PET

Xiong, Mengfei; Roshanbin, Sahar; Sehlin, Dag; Hansen, Hanne D. et al.

Preclinical evaluation of Affibody molecule ¹⁸F-TZ-Z_AM106 for PET imaging of DGCR2

Cheung, Pierre; Thorngren, Julia; Zhang, Bo; Vasylovska, Svitlana et al.

[¹¹C]PiB binding after treatment with an amyloid-beta antibody

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Aguilar, Ximena et al.

Aβ targeting ImmunoPET: Brain pharmacokinetics comparison between a brain penetrating and a regular antibody

Schlein, Eva; Lopes van den Broek, Sara; Dallas, Tiffany; Andersson, Ken G. et al.

Synthesis and Preclinical Evaluation of GRPR Antagonist [¹⁸F]-MeTz-PEG₂-RM26 for Position Emission Tomography

Lundmark, Fanny; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Tolmachev, Vladimir et al.