Srinivas Akula

Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues

Fu, Zhirong; Akula, Srinivas; Thorpe, Michael; Chahal, Gurdeep et al.

Ingår i Developmental and Comparative Immunology, s. 160-169, 2019

• DOI för Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues

The mast cell transcriptome and the evolution of granule proteins and Fc receptors

Akula, Srinivas

2019

• Ladda ner fulltext (pdf) av The mast cell transcriptome and the evolution of granule proteins and Fc receptors

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities

Thorpe, Michael; Fu, Zhirong; Chahal, Gurdeep; Akula, Srinivas et al.

Ingår i PLOS ONE, 2018

• DOI för Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities

Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5

Thorpe, Michael; Fu, Zhirong; Albat, Emanuelle; Akula, Srinivas et al.

Ingår i PLOS ONE, 2018

• DOI för Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5
• Ladda ner fulltext (pdf) av Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5

Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability

Fu, Zhirong; Thorpe, Michael; Akula, Srinivas; Chahal, Gurdeep et al.

Ingår i Frontiers in Immunology, 2018

• DOI för Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability
• Ladda ner fulltext (pdf) av Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability

Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals

Hellman, Lars T.; Akula, Srinivas; Thorpe, Michael; Fu, Zhirong

Ingår i Frontiers in Immunology, 2017

• DOI för Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals
• Ladda ner fulltext (pdf) av Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals

The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution

Akula, Srinivas; Hellman, Lars

Ingår i IGM AND ITS RECEPTORS AND BINDING PROTEINS, s. 1-23, SPRINGER-VERLAG BERLIN, 2017

• DOI för The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution

Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution

Fu, Zhirong; Thorpe, Michael; Akula, Srinivas; Hellman, Lars

Ingår i PLOS ONE, 2016

• DOI för Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution
• Ladda ner fulltext (pdf) av Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution

Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells

Thorpe, Michael; Akula, Srinivas; Hellman, Lars

Ingår i Developmental And Comparative Immunology, s. 84-95, 2016

• DOI för Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells

Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution

Akula, Srinivas; Thorpe, Michael; Boinapally, Vamsi; Hellman, Lars

Ingår i PLOS ONE, 2015

• DOI för Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution
• Ladda ner fulltext (pdf) av Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution

Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution

Akula, Srinivas; Mohammadamin, Sayran; Hellman, Lars

Ingår i PLOS ONE, 2014

• DOI för Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution
• Ladda ner fulltext (pdf) av Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution

The mouse mast cell transcriptome

Akula, Srinivas; Paivandy, Aida; Thorpe, Michael; Pjeler, Gunnar et al.

Immunity: defense against infections essential for all living organisms

Akula, Srinivas; Wernersson, Sara; Hellman, Lars

Ingår i Frontiers in Immunology, 2026

• DOI för Immunity: defense against infections essential for all living organisms
• Ladda ner fulltext (pdf) av Immunity: defense against infections essential for all living organisms

Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material

Akula, Srinivas; Lara, Sandra; Olsson, Anna-Karin; Hellman, Lars

Ingår i Frontiers in Cellular and Infection Microbiology, 2025

• DOI för Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material
• Ladda ner fulltext (pdf) av Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material

Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice

Allam, Venkata; Akula, Srinivas; Waern, Ida; Taha, Sowsan et al.

Ingår i Inflammation, s. 806-819, 2025

• DOI för Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice
• Ladda ner fulltext (pdf) av Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice

Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma

Allam, Venkata Sita Rama Raju; Montpeyó, David; Beau, Fabrice; Taha, Sowsan et al.

Ingår i Inflammation Research, 2025

• DOI för Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma
• Ladda ner fulltext (pdf) av Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma

Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)

Valentini, Paolo; Akula, Srinivas; Alvarado-Vazquez, Perla Abigail; Hallgren, Jenny et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)
• Ladda ner fulltext (pdf) av Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)

Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material

Akula, Srinivas; Lara, Sandra; Olsson, Anna-Karin; Hellman, Lars

Ingår i Frontiers in Cellular and Infection Microbiology, 2025

• DOI för Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material
• Ladda ner fulltext (pdf) av Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material

Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice

Allam, Venkata; Akula, Srinivas; Waern, Ida; Taha, Sowsan et al.

Ingår i Inflammation, s. 806-819, 2025

• DOI för Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice
• Ladda ner fulltext (pdf) av Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice

Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma

Allam, Venkata Sita Rama Raju; Montpeyó, David; Beau, Fabrice; Taha, Sowsan et al.

Ingår i Inflammation Research, 2025

• DOI för Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma
• Ladda ner fulltext (pdf) av Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma

Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)

Valentini, Paolo; Akula, Srinivas; Alvarado-Vazquez, Perla Abigail; Hallgren, Jenny et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)
• Ladda ner fulltext (pdf) av Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus)

Characterization of Freshly Isolated Human Peripheral Blood B Cells, Monocytes, CD4⁺ and CD8⁺ T Cells, and Skin Mast Cells by Quantitative Transcriptomics

Akula, Srinivas; Alvarado-Vazquez, Abigail; Mendez Enriquez, Erika Haide; Bal, Gürkan et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Characterization of Freshly Isolated Human Peripheral Blood B Cells, Monocytes, CD4⁺ and CD8⁺ T Cells, and Skin Mast Cells by Quantitative Transcriptomics
• Ladda ner fulltext (pdf) av Characterization of Freshly Isolated Human Peripheral Blood B Cells, Monocytes, CD4⁺ and CD8⁺ T Cells, and Skin Mast Cells by Quantitative Transcriptomics

The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells

Thorpe, Michael; Akula, Srinivas; Fu, Zhirong; Hellman, Lars

Ingår i International Journal of Molecular Sciences, 2024

• DOI för The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells
• Ladda ner fulltext (pdf) av The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells

Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology

Akula, Srinivas; Tripathi, Shiva Raj; Franke, Kristin; Wernersson, Sara et al.

Ingår i Cells, 2024

• DOI för Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology
• Ladda ner fulltext (pdf) av Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology

Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity

Aybay, Erdem; Ryu, Jinhye; Fu, Zhirong; Akula, Srinivas et al.

Ingår i Frontiers in Immunology, 2023

• DOI för Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity
• Ladda ner fulltext (pdf) av Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity

Identification of the Major Protein Components of Human and Cow Saliva

Akula, Srinivas; Welinder, Charlotte; Fu, Zhirong; Olsson, Anna-Karin et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Identification of the Major Protein Components of Human and Cow Saliva
• Ladda ner fulltext (pdf) av Identification of the Major Protein Components of Human and Cow Saliva

Two granzyme A/K homologs in Zebra mbuna have different specificities, one classical tryptase and one with chymase activity

Aybay, Erdem; Elkhalifa, Mamoun; Akula, Srinivas; Wernersson, Sara et al.

Ingår i Developmental and Comparative Immunology, 2023

• DOI för Two granzyme A/K homologs in Zebra mbuna have different specificities, one classical tryptase and one with chymase activity
• Ladda ner fulltext (pdf) av Two granzyme A/K homologs in Zebra mbuna have different specificities, one classical tryptase and one with chymase activity

Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases

Ryu, Jinhye; Fu, Zhirong; Akula, Srinivas; Olsson, Anna-Karin et al.

Ingår i Developmental and Comparative Immunology, 2022

• DOI för Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases
• Ladda ner fulltext (pdf) av Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases

Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems

Paivandy, Aida; Akula, Srinivas; Lara, Sandra; Fu, Zhirong et al.

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems
• Ladda ner fulltext (pdf) av Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems

Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation

Akula, Srinivas; Lara, Sandra; Olsson, Anna-Karin; Hellman, Lars

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation
• Ladda ner fulltext (pdf) av Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation

Analysis of the mast cell expressed carboxypeptidase A3 and its structural and evolutionary relationship to other vertebrate carboxypeptidases

Akula, Srinivas; Hellman, Lars; Aviles, Francesc Xavier; Wernersson, Sara

Ingår i Developmental and Comparative Immunology, 2022

• DOI för Analysis of the mast cell expressed carboxypeptidase A3 and its structural and evolutionary relationship to other vertebrate carboxypeptidases
• Ladda ner fulltext (pdf) av Analysis of the mast cell expressed carboxypeptidase A3 and its structural and evolutionary relationship to other vertebrate carboxypeptidases

Chicken cathepsin G-like - A highly specific serine protease with a peculiar tryptase specificity expressed by chicken thrombocytes

Fu, Zhirong; Akula, Srinivas; Olsson, Anna-Karin; Hellman, Lars

Ingår i Developmental and Comparative Immunology, 2022

• DOI för Chicken cathepsin G-like - A highly specific serine protease with a peculiar tryptase specificity expressed by chicken thrombocytes
• Ladda ner fulltext (pdf) av Chicken cathepsin G-like - A highly specific serine protease with a peculiar tryptase specificity expressed by chicken thrombocytes

Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins

Fu, Zhirong; Akula, Srinivas; Thorpe, Michael; Hellman, Lars

Ingår i Biological chemistry (Print), s. 861-867, 2021

• DOI för Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins
• Ladda ner fulltext (pdf) av Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins

Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity

Fu, Zhirong; Akula, Srinivas; Qiao, Chang; Ryu, Jinhye et al.

Ingår i PLOS ONE, 2021

• DOI för Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity
• Ladda ner fulltext (pdf) av Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity

Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases

Fu, Zhirong; Akula, Srinivas; Olsson, Anna-Karin; Kervinen, Jukka et al.

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases
• Ladda ner fulltext (pdf) av Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases

Extended Cleavage Specificities of Two Mast Cell Chymase-Related Proteases and One Granzyme B-Like Protease from the Platypus, a Monotreme

Fu, Zhirong; Akula, Srinivas; Thorpe, Michael; Hellman, Lars

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Extended Cleavage Specificities of Two Mast Cell Chymase-Related Proteases and One Granzyme B-Like Protease from the Platypus, a Monotreme
• Ladda ner fulltext (pdf) av Extended Cleavage Specificities of Two Mast Cell Chymase-Related Proteases and One Granzyme B-Like Protease from the Platypus, a Monotreme

Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells

Berglund, Petter; Akula, Srinivas; Fu, Zhirong; Thorpe, Michael et al.

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells
• Ladda ner fulltext (pdf) av Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells

Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33

Teufelberger, Andrea R.; Van Nevel, Sharon; Hulpiau, Paco; Nordengrun, Maria et al.

Ingår i Frontiers in Immunology, 2020

• DOI för Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33
• Ladda ner fulltext (pdf) av Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33

Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3

Fu, Zhirong; Akula, Srinivas; Thorpe, Michael; Hellman, Lars

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3
• Ladda ner fulltext (pdf) av Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3

Protective role of mouse mast cell tryptase Mcpt6 in melanoma.

Grujic, Mirjana; Hellman, Lars; Gustafson, Ann-Marie; Akula, Srinivas et al.

Ingår i Pigment Cell & Melanoma Research, s. 579-590, 2020

• DOI för Protective role of mouse mast cell tryptase Mcpt6 in melanoma.

How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells?: A Comparative Transcriptome Analysis of BMMCs and Peritoneal Mast Cells

Akula, Srinivas; Paivandy, Aida; Fu, Zhirong; Thorpe, Michael et al.

Ingår i Cells, 2020

• DOI för How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells?: A Comparative Transcriptome Analysis of BMMCs and Peritoneal Mast Cells
• Ladda ner fulltext (pdf) av How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells?: A Comparative Transcriptome Analysis of BMMCs and Peritoneal Mast Cells

Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity

Akula, Srinivas; Paivandy, Aida; Fu, Zhirong; Thorpe, Michael et al.

Ingår i CELLS, 2020

• DOI för Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity
• Ladda ner fulltext (pdf) av Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity

Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity

Fu, Zhirong; Akula, Srinivas; Thorpe, Michael; Hellman, Lars

Ingår i International Journal of Molecular Sciences, 2019

• DOI för Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity
• Ladda ner fulltext (pdf) av Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity

Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases

Zhongwei, Yuan; Akula, Srinivas; Fu, Zhirong; de Garavilla, Lawrence et al.

Ingår i International Journal of Molecular Sciences, 2019

• DOI för Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases
• Ladda ner fulltext (pdf) av Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases

Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues

Fu, Zhirong; Akula, Srinivas; Thorpe, Michael; Chahal, Gurdeep et al.

Ingår i Developmental and Comparative Immunology, s. 160-169, 2019

• DOI för Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities

Thorpe, Michael; Fu, Zhirong; Chahal, Gurdeep; Akula, Srinivas et al.

Ingår i PLOS ONE, 2018

• DOI för Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities

Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5

Thorpe, Michael; Fu, Zhirong; Albat, Emanuelle; Akula, Srinivas et al.

Ingår i PLOS ONE, 2018

• DOI för Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5
• Ladda ner fulltext (pdf) av Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5

Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability

Fu, Zhirong; Thorpe, Michael; Akula, Srinivas; Chahal, Gurdeep et al.

Ingår i Frontiers in Immunology, 2018

• DOI för Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability
• Ladda ner fulltext (pdf) av Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability

Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution

Fu, Zhirong; Thorpe, Michael; Akula, Srinivas; Hellman, Lars

Ingår i PLOS ONE, 2016

• DOI för Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution
• Ladda ner fulltext (pdf) av Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution

Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells

Thorpe, Michael; Akula, Srinivas; Hellman, Lars

Ingår i Developmental And Comparative Immunology, s. 84-95, 2016

• DOI för Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells

Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution

Akula, Srinivas; Thorpe, Michael; Boinapally, Vamsi; Hellman, Lars

Ingår i PLOS ONE, 2015

• DOI för Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution
• Ladda ner fulltext (pdf) av Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution

Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution

Akula, Srinivas; Mohammadamin, Sayran; Hellman, Lars

Ingår i PLOS ONE, 2014

• DOI för Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution
• Ladda ner fulltext (pdf) av Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution

Immunity: defense against infections essential for all living organisms

Akula, Srinivas; Wernersson, Sara; Hellman, Lars

Ingår i Frontiers in Immunology, 2026

• DOI för Immunity: defense against infections essential for all living organisms
• Ladda ner fulltext (pdf) av Immunity: defense against infections essential for all living organisms

The Evolutionary History of the Chymase Locus -a Locus Encoding Several of the Major Hematopoietic Serine Proteases

Akula, Srinivas; Fu, Zhirong; Wernersson, Sara; Hellman, Lars

Ingår i International Journal of Molecular Sciences, 2021

• DOI för The Evolutionary History of the Chymase Locus -a Locus Encoding Several of the Major Hematopoietic Serine Proteases
• Ladda ner fulltext (pdf) av The Evolutionary History of the Chymase Locus -a Locus Encoding Several of the Major Hematopoietic Serine Proteases

Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals

Hellman, Lars T.; Akula, Srinivas; Thorpe, Michael; Fu, Zhirong

Ingår i Frontiers in Immunology, 2017

• DOI för Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals
• Ladda ner fulltext (pdf) av Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals

The mast cell transcriptome and the evolution of granule proteins and Fc receptors

Akula, Srinivas

2019

• Ladda ner fulltext (pdf) av The mast cell transcriptome and the evolution of granule proteins and Fc receptors

The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution

Akula, Srinivas; Hellman, Lars

Ingår i IGM AND ITS RECEPTORS AND BINDING PROTEINS, s. 1-23, SPRINGER-VERLAG BERLIN, 2017

• DOI för The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution

The mouse mast cell transcriptome

Akula, Srinivas; Paivandy, Aida; Thorpe, Michael; Pjeler, Gunnar et al.