Andreas Mårtensson
Professor vid Institutionen för kvinnors och barns hälsa; Internationell barnhälsa och nutrition
- E-post:
- andreas.martensson@uu.se
- Besöksadress:
- MTC-huset, Dag Hammarskjölds väg 14B, 1 tr
752 37 Uppsala - Postadress:
- Akademiska sjukhuset
751 85 UPPSALA
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Nyckelord
- child health
- malaria
- pediatric infectious diseases
Biografi
During my clinical professional career I have always had a special interest in international pediatric infectious diseases and tropical medicine, particularly in resource limited settings. My specific training in infectious diseases and tropical medicine combined with long-term clinical experience both from Asia (Pakistan) and Africa (Zimbabwe) have all toghether been a great advantage when developing my research career over the last decade.
My research activities have over time involved both clinical, epidemiological, experimental and qualitative studies within the field of international child health, with a clear focus on a leading cause of child morbidity and mortality globally, namely malaria. My research activities have since 2005 to date resulted in approximately 70 original research reports. My scientific strength is the diversity of my work, i.e. that I have combined different methodologies and actively participate in various research-networks/consortia.
I am presently professor and head of research of international child health and nutrition at International Maternal and Child Health (IMCH), Department of Women’s and Children’s Health, Uppsala University.
Publikationer
Senaste publikationer
- Strong isolation by distance and evidence of population microstructure reflect ongoing Plasmodium falciparum transmission in Zanzibar (2024)
- Diagnosis of soil-transmitted helminth infections with digital mobile microscopy and artificial intelligence in a resource-limited setting (2024)
- Diagnostic accuracy of foot length measurement for identification of preterm newborn in rural Sindh, Pakistan (2024)
- Exploring gestational age, and birth weight assessment in Thatta district, Sindh, Pakistan (2024)
- Assessing the diagnostic accuracy of postnatal clinical scoring methods and foot length measurement for estimating gestational age and birthweight of newborns in low- and middle-income countries (2024)
Alla publikationer
Artiklar
- Strong isolation by distance and evidence of population microstructure reflect ongoing Plasmodium falciparum transmission in Zanzibar (2024)
- Diagnosis of soil-transmitted helminth infections with digital mobile microscopy and artificial intelligence in a resource-limited setting (2024)
- Diagnostic accuracy of foot length measurement for identification of preterm newborn in rural Sindh, Pakistan (2024)
- Exploring gestational age, and birth weight assessment in Thatta district, Sindh, Pakistan (2024)
- Assessing the diagnostic accuracy of postnatal clinical scoring methods and foot length measurement for estimating gestational age and birthweight of newborns in low- and middle-income countries (2024)
- Socio-demographic characteristics of children and young people with primary brain tumours (2024)
- Assessing the acceptability and feasibility of reactive drug administration for malaria elimination in a Plasmodium vivax predominant setting (2023)
- Variability in white blood cell count during uncomplicated malaria and implications for parasite density estimation (2023)
- Socio-demographic and antenatal risk factors of brain tumor in children and young people (2023)
- Patterns and contextual determinants of antibiotic prescribing for febrile under-five outpatients at primary and secondary healthcare facilities in Bugisu, Eastern Uganda (2022)
- Temporal distribution of Plasmodium falciparum recrudescence following artemisinin-based combination therapy (2022)
- Pneumococcal concentration and serotype distribution in preschool children with radiologically confirmed pneumonia compared to healthy controls prior to introduction of pneumococcal vaccination in Zanzibar (2022)
- Safety and Tolerability of an Antimalarial Herbal Remedy in Healthy Volunteers (2022)
- Haematological consequences of acute uncomplicated falciparum malaria (2022)
- A single low dose of primaquine is safe and sufficient to reduce transmission of Plasmodium falciparum gametocytes regardless of cytochrome P450 2D6 enzyme activity in Bagamoyo district, Tanzania (2022)
- Protein biomarker profiles in serum and CSF in 158 patients with PTLDS or persistent symptoms after presumed tick-bite exposure compared to those in patients with confirmed acute neuroborreliosis (2022)
- Myxovirus resistance protein A for discriminating between viral and bacterial lower respiratory tract infections in children (2022)
- Plasmodium falciparum Drug Resistance Genes pfmdr1 and pfcrt In Vivo Co-Expression During Artemether-Lumefantrine Therapy (2022)
- Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide (2022)
- Field evaluation of typhoid conjugate vaccine in a catch-up campaign among children aged 9 months to 15 years in Sindh, Pakistan (2022)
- Determinants of trends in reported antibiotic use among sick children under five years of age across low-income and middle-income countries in 2005-17 (2021)
- Effectiveness of peer-supervision on pediatric fever illness treatment among registered private drug sellers in East-Central Uganda (2021)
- Bartonella spp. seroprevalence in tick-exposed Swedish patients with persistent symptoms (2021)
- Etiology of Clinical Community-Acquired Pneumonia in Swedish Children Aged 1-59 Months with High Pneumococcal Vaccine Coverage (2021)
- Vasculitis due to Candidatus Neoehrlichia mikurensis (2021)
- A comprehensive clinical and laboratory evaluation of 224 patients with persistent symptoms attributed to presumed tick-bite exposure (2021)
- Influence of cytochrome P450 (CYP) 2C8 polymorphisms on the efficacy and tolerability of artesunate-amodiaquine treatment of uncomplicated Plasmodium falciparum malaria in Zanzibar (2021)
- Point-of-care testing in a high-income country paediatric emergency department (2021)
- Trends in reported antibiotic use among children under 5 years of age with fever, diarrhoea, or cough with fast or difficult breathing across low-income and middle-income countries in 2005-17 (2020)
- 'I know those people will be approachable and not mistreat us' (2020)
- Regulatory inspection of registered private drug shops in East-Central Uganda-what it is versus what it should be (2020)
- Peer supervision experiences of drug sellers in a rural district in East-Central Uganda (2020)
- Efficacy of zinc as adjunctive pneumonia treatment in children aged 2 to 60 months in low-income and middle-income countries (2020)
- Point-of-Care Approaches for Meningitis Diagnosis in a Low-Resource Setting (Southwestern Uganda) (2020)
- Prevalence of CYP2C8*2 and *3 among Eritreans and its Potential Impact on Artesunate/Amodiaquine Treatment (2020)
- A novel deep learning-based point-of-care diagnostic method for detecting Plasmodium falciparum with fluorescence digital microscopy. (2020)
- Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether-lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania– a randomized controlled trial. (2020)
- Electrocardiographic safety evaluation of extended artemether-lumefantrine treatment in patients with uncomplicated Plasmodium falciparum malaria in Bagamoyo District, Tanzania (2020)
- Falciparum malaria from coastal Tanzania and Zanzibar remains highly connected despite effective control efforts on the archipelago (2020)
- Increased Sensitivity of Plasmodium falciparum to Artesunate/Amodiaquine Despite 14 Years as First-Line Malaria Treatment, Zanzibar (2020)
- Stable high frequencies of sulfadoxine-pyrimethamine resistance associated mutations and absence of K13 mutations inPlasmodium falciparum3 and 4 years after the introduction of artesunate plus sulfadoxine-pyrimethamine in Ujjain, Madhya Pradesh, India (2020)
- Efficacy of single dose primaquine with artemisinin combination therapy on P. falciparum gametocytes and transmission (2020)
- Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments (2019)
- From high to low malaria transmission in Zanzibar-challenges and opportunities to achieve elimination (2019)
- Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria (2019)
- Detection of sub-microscopic blood levels of Plasmodium falciparum using Tandem Oligonucleotide Repeat Cascade Amplification (TORCA) assay with an attomolar detection limit (2019)
- Prevalence of and Risk Factors Associated with Polymerase Chain Reaction-Determined Plasmodium falciparum Positivity on Day 3 after Initiation of Artemether-Lumefantrine Treatment for Uncomplicated Malaria in Bagamoyo District, Tanzania (2019)
- Introducing a New Algorithm for Classification of Etiology in Studies on Pediatric Pneumonia (2019)
- Plasmodium falciparum K13 expression associated with parasite clearance during artemisinin-based combination therapy (2019)
- Coinfection with Enteric Pathogens in East African Children with Acute Gastroenteritis-Associations and Interpretations (2018)
- Pathogen Clearance and New Respiratory Tract Infections Among Febrile Children in Zanzibar Investigated With Multitargeting Real-Time Polymerase Chain Reaction on Paired Nasopharyngeal Swab Samples (2018)
- Absence of Plasmodium falciparum K13 Propeller Domain Polymorphisms among Field Isolates Collected from the Brazilian Amazon Basin between 1984 and 2011 (2018)
- Plasmodium falciparum Plasmepsin 2 Duplications, West Africa (2018)
- Can malaria rapid diagnostic tests by drug sellers under feld conditions classify children 5 years old or less with or without Plasmodium falciparum malaria? (2018)
- Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women (2018)
- A cluster randomised controlled trial of two rounds of mass drug administration in Zanzibar, a malaria pre-elimination setting-high coverage and safety, but no significant impact on transmission. (2018)
- A vertical flow paper-microarray assay with isothermal DNA amplification for detection of Neisseria meningitidis (2018)
- Serological reactivity to Anaplasma phagocytophilum in neoehrlichiosis patients (2018)
- Rapid Clearance and Frequent Reinfection With Enteric Pathogens Among Children With Acute Diarrhea in Zanzibar. (2017)
- Field Evaluation of a High Throughput Loop Mediated Isothermal Amplification Test for the Detection of Asymptomatic Plasmodium Infections in Zanzibar (2017)
- Spatial Distribution of Falciparum Malaria Infections in Zanzibar (2017)
- The Impact of Introducing Malaria Rapid Diagnostic Tests on Fever Case Management (2017)
- Improving prescribing practices with rapid diagnostic tests (RDTs) (2017)
- Point-of-care mobile digital microscopy and deep learning for the detection of soil-transmitted helminths and Schistosoma haematobium (2017)
- Impact of introduction of rapid diagnostic tests for malaria on antibiotic prescribing (2017)
- Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naive areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976-78 (2017)
- Sustained High Cure Rate of Artemether-Lumefantrine against Uncomplicated Plasmodium falciparum Malaria after 8 Years of Its Wide-Scale Use in Bagamoyo District, Tanzania (2017)
- Sustained High Cure Rate Of Artemether Lumefantrine In Tanzania (2017)
- Health care workers' perceptions of point-of-care testing in a low-income country-A qualitative study in Southwestern Uganda (2017)
- MRP2/ABCC2 C1515Y polymorphism modulates exposure to lumefantrine during artemether-lumefantrine antimalarial therapy (2017)
- Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa (2017)
- Acute Uncomplicated Febrile Illness in Children Aged 2-59 months in Zanzibar (2016)
- Pooled Amplicon Deep Sequencing of Candidate Plasmodium falciparum Transmission-Blocking Vaccine Antigens (2016)
- A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections (2016)
- Safety of a single low-dose of primaquine in addition to standard artemether-lumefantrine regimen for treatment of acute uncomplicated Plasmodium falciparum malaria in Tanzania (2016)
- Adding a single low-dose of primaquine (0.25 mg/kg) to artemether-lumefantrine did not compromise treatment outcome of uncomplicated Plasmodium falciparum malaria in Tanzania (2016)
- Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy (2016)
- Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative (2015)
- The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria (2015)
- Loop-mediated isothermal amplification (LAMP) for point-of-care detection of asymptomatic low-density malaria parasite carriers in Zanzibar (2015)
- Mass Screening and Treatment on the Basis of Results of a Plasmodium falciparum-Specific Rapid Diagnostic Test Did Not Reduce Malaria Incidence in Zanzibar (2015)
- Field deployment of loop-mediated isothermal amplification for centralized mass-screening of asymptomatic malaria in Zanzibar (2015)
- Characterising temporal trends in asymptomatic Plasmodium infections and transporter polymorphisms during transition from high to low transmission in Zanzibar, 2005-2013. (2015)
- SYBR Green Real-Time PCR-RFLP Assay Targeting the Plasmodium Cytochrome B Gene - A Highly Sensitive Molecular Tool for Malaria Parasite Detection and Species Determination (2015)
- Loop mediated isothermal amplification (LAMP) accurately detects malaria DNA from filter paper blood samples of low density parasitaemias (2014)
- Characterization of drug resistance associated genetic polymorphisms among Plasmodium falciparum field isolates in Ujjain, Madhya Pradesh, India. (2014)
- Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes (2014)
- Classification of non-severe acute febrile illness as bacterial or non-bacterial
- Perceived quality of paediatric fever care from private drug shops and care-seeking choice in South Western Uganda: data from household surveys.
- Electrocardiographic safety evaluation of a prolonged artemether-lumefantrine treatment in patients with uncomplicated Plasmodium falciparum malaria in Bagamoyo District, Tanzania.
- Healthcare providers’ considerations in antibiotic prescribing and administration for febrile under-five patients attending primary and secondary healthcare facilities in eastern Uganda- a qualitative study
- MicroRNA expression and neurocognitive outcomes in children and young people with primary brain tumor in Karachi, Pakistan