Patrick D Sinko

Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis

Naranjani, Benyamin; Hossain, Shakhawath; Tjakra, Marco; Azhand, Pardis et al.

Ingår i Drug Delivery, 2026

• DOI för Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis
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Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics

Sinko, Patrick D.; Parker, Louis; Prahl Wittberg, Lisa; Bergström, Christel A. S.

Ingår i International Journal of Pharmaceutics, 2024

• DOI för Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics
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Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer

Naranjani, Benyamin; Sinko, Patrick D.; Bergström, Christel; Gogoll, A et al.

Ingår i International Journal of Biological Macromolecules, 2023

• DOI för Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer
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Intrinsic lipolysis rate for systematic design of lipid-based formulations

Jacobsen, Ann-Christin; Kabedev, Aleksei; Sinko, Patrick D.; Palm, Johan E. et al.

Ingår i Drug Delivery and Translational Research, s. 1288-1304, 2023

• DOI för Intrinsic lipolysis rate for systematic design of lipid-based formulations
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Particle Size, Dose, and Confinement Affect Passive Diffusion Flux through the Membrane Concentration Boundary Layer

Sinko, Patrick D.; Salehi, Niloufar; Halseth, Troy; Meyer, Pamela J. et al.

Ingår i Molecular Pharmaceutics, s. 201-215, 2023

• DOI för Particle Size, Dose, and Confinement Affect Passive Diffusion Flux through the Membrane Concentration Boundary Layer

Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis

Naranjani, Benyamin; Hossain, Shakhawath; Tjakra, Marco; Azhand, Pardis et al.

Ingår i Drug Delivery, 2026

• DOI för Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis
• Ladda ner fulltext (pdf) av Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis

Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics

Sinko, Patrick D.; Parker, Louis; Prahl Wittberg, Lisa; Bergström, Christel A. S.

Ingår i International Journal of Pharmaceutics, 2024

• DOI för Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics
• Ladda ner fulltext (pdf) av Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics

Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer

Naranjani, Benyamin; Sinko, Patrick D.; Bergström, Christel; Gogoll, A et al.

Ingår i International Journal of Biological Macromolecules, 2023

• DOI för Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer
• Ladda ner fulltext (pdf) av Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer

Intrinsic lipolysis rate for systematic design of lipid-based formulations

Jacobsen, Ann-Christin; Kabedev, Aleksei; Sinko, Patrick D.; Palm, Johan E. et al.

Ingår i Drug Delivery and Translational Research, s. 1288-1304, 2023

• DOI för Intrinsic lipolysis rate for systematic design of lipid-based formulations
• Ladda ner fulltext (pdf) av Intrinsic lipolysis rate for systematic design of lipid-based formulations

Particle Size, Dose, and Confinement Affect Passive Diffusion Flux through the Membrane Concentration Boundary Layer

Sinko, Patrick D.; Salehi, Niloufar; Halseth, Troy; Meyer, Pamela J. et al.

Ingår i Molecular Pharmaceutics, s. 201-215, 2023

• DOI för Particle Size, Dose, and Confinement Affect Passive Diffusion Flux through the Membrane Concentration Boundary Layer

Ultrathin, Large-Area Membrane Diffusion Cell for pH-Dependent Simultaneous Dissolution and Absorption Studies

Sinko, Patrick D.; Harris, Sarah; Salehi, Niloufar; Meyer, Pamela J. et al.

Ingår i Molecular Pharmaceutics, s. 2319-2328, 2020

• DOI för Ultrathin, Large-Area Membrane Diffusion Cell for pH-Dependent Simultaneous Dissolution and Absorption Studies

Revealing macromolecular drug absorption under the migrating motor complex: An in vivo-CFD investigation of anaesthesia effects, permeation enhancement, and species variability

Naranjani, Benyamin; Berg, Staffan; Bergström, Christel A. S.; Hossain, Shakhawath et al.

Investigating the role of intestinal mucus as a barrier for oral delivery of macromolecules and permeation enhancers

Naranjani, Benyamin; Hossain, Shakhawath; Tjakra, Marco; Sinko, Patrick D. et al.