Damian Bartuzi

Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies

Wawruszak, Anna; Luszczki, Jarogniew; Bartuzi, Damian; Kalafut, Joanna et al.

Ingår i Journal of Enzyme Inhibition and Medicinal Chemistry, 2025

• DOI för Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies
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Biased signaling via serotonin 5-HT2A receptor: From structural aspects to in vitro and in vivo pharmacology

Jastrzebski, Michal K.; Wojcik, Piotr; Grudzinska, Angelika; Andreozzi, Giorgia et al.

Ingår i Acta Pharmaceutica Sinica B, s. 4438-4455, 2025

• DOI för Biased signaling via serotonin 5-HT2A receptor: From structural aspects to in vitro and in vivo pharmacology
• Ladda ner fulltext (pdf) av Biased signaling via serotonin 5-HT2A receptor: From structural aspects to in vitro and in vivo pharmacology

Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor

Lim, Herman D.; Bartuzi, Damian; Keen, Alastair C.; Rauffenbart, Caroline et al.

Ingår i ACS Chemical Neuroscience, s. 2295-2311, 2025

• DOI för Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor
• Ladda ner fulltext (pdf) av Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor

Molecular Dynamics Simulations in Protein–Protein Docking

Cieślak, Dominika; Kabelka, Ivo; Bartuzi, Damian

Ingår i Protein-Protein Docking, s. 91-106, Humana Press, 2024

• DOI för Molecular Dynamics Simulations in Protein–Protein Docking

Secondary Binding Site of CYP17A1 in Enhanced Sampling Simulations

Wrobel, Tomasz M.; Bartuzi, Damian; Kaczor, Agnieszka A.

Ingår i Journal of Chemical Information and Modeling, s. 7679-7686, 2024

• DOI för Secondary Binding Site of CYP17A1 in Enhanced Sampling Simulations
• Ladda ner fulltext (pdf) av Secondary Binding Site of CYP17A1 in Enhanced Sampling Simulations

Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies

Wawruszak, Anna; Luszczki, Jarogniew; Bartuzi, Damian; Kalafut, Joanna et al.

Ingår i Journal of Enzyme Inhibition and Medicinal Chemistry, 2025

• DOI för Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies
• Ladda ner fulltext (pdf) av Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies

Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor

Lim, Herman D.; Bartuzi, Damian; Keen, Alastair C.; Rauffenbart, Caroline et al.

Ingår i ACS Chemical Neuroscience, s. 2295-2311, 2025

• DOI för Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor
• Ladda ner fulltext (pdf) av Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor

Secondary Binding Site of CYP17A1 in Enhanced Sampling Simulations

Wrobel, Tomasz M.; Bartuzi, Damian; Kaczor, Agnieszka A.

Ingår i Journal of Chemical Information and Modeling, s. 7679-7686, 2024

• DOI för Secondary Binding Site of CYP17A1 in Enhanced Sampling Simulations
• Ladda ner fulltext (pdf) av Secondary Binding Site of CYP17A1 in Enhanced Sampling Simulations

Discovery and in vitro Evaluation of Novel Serotonin 5-HT_2A Receptor Ligands Identified Through Virtual Screening

Zieba, Agata; Bartuzi, Damian; Stepnicki, Piotr; Matosiuk, Dariusz et al.

Ingår i ChemMedChem, 2024

• DOI för Discovery and in vitro Evaluation of Novel Serotonin 5-HT_2A Receptor Ligands Identified Through Virtual Screening

Development and Characterization of Novel Selective, Non-Basic Dopamine D-2 Receptor Antagonists for the Treatment of Schizophrenia

Stepnicki, Piotr; Wosko, Sylwia; Bartyzel, Agata; Zieba, Agata et al.

Ingår i Molecules, 2023

• DOI för Development and Characterization of Novel Selective, Non-Basic Dopamine D-2 Receptor Antagonists for the Treatment of Schizophrenia
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Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes

Bartuzi, Damian; Kedzierska, Ewa; Targowska-Duda, Katarzyna M.; Koszla, Oliwia et al.

Ingår i Scientific Reports, 2022

• DOI för Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes
• Ladda ner fulltext (pdf) av Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes

Biased signaling via serotonin 5-HT2A receptor: From structural aspects to in vitro and in vivo pharmacology

Jastrzebski, Michal K.; Wojcik, Piotr; Grudzinska, Angelika; Andreozzi, Giorgia et al.

Ingår i Acta Pharmaceutica Sinica B, s. 4438-4455, 2025

• DOI för Biased signaling via serotonin 5-HT2A receptor: From structural aspects to in vitro and in vivo pharmacology
• Ladda ner fulltext (pdf) av Biased signaling via serotonin 5-HT2A receptor: From structural aspects to in vitro and in vivo pharmacology

Allosteric Modulators of Dopamine D-2 Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis

Kaczor, Agnieszka A.; Wrobel, Tomasz M.; Bartuzi, Damian

Ingår i Molecules, 2023

• DOI för Allosteric Modulators of Dopamine D-2 Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis
• Ladda ner fulltext (pdf) av Allosteric Modulators of Dopamine D-2 Receptors for Fine-Tuning of Dopaminergic Neurotransmission in CNS Diseases: Overview, Pharmacology, Structural Aspects and Synthesis

Molecular Dynamics Simulations in Protein–Protein Docking

Cieślak, Dominika; Kabelka, Ivo; Bartuzi, Damian

Ingår i Protein-Protein Docking, s. 91-106, Humana Press, 2024

• DOI för Molecular Dynamics Simulations in Protein–Protein Docking