Josephus Buijs

Regulatory effects of RNA-protein interactions revealed by reporter assays of bacteria grown on solid media

Pérez-Ropero, Guillermo; Dolcemascolo, Roswitha; Pérez-Ràfols, Anna; Andersson, Karl et al.

Ingår i Biosensors, 2025

• DOI för Regulatory effects of RNA-protein interactions revealed by reporter assays of bacteria grown on solid media
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Unraveling the Bivalent and Rapid Interactions Between a Multivalent RNA Recognition Motif and RNA: A Kinetic Approach

Pérez-Ropero, Guillermo; Perez-Rafols, Anna; Martelli, Tommasso; Danielson, U. Helena et al.

Ingår i Biochemistry, s. 2816-2829, 2024

• DOI för Unraveling the Bivalent and Rapid Interactions Between a Multivalent RNA Recognition Motif and RNA: A Kinetic Approach
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Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

Dolcemascolo, Roswitha; Heras-Hernandez, Maria; Goiriz, Lucas; Montagud-Martinez, Roser et al.

Ingår i eLIFE, 2024

• DOI för Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria
• Ladda ner fulltext (pdf) av Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta

Rofo, Fadi; Buijs, Jos; Falk, Ronny; Honek, Ken et al.

Ingår i Translational Neurodegeneration, 2021

• DOI för Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta
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Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength

Bondza, Sina; Marosan, Anita; Kara, Sibel; Loesing, Josephine et al.

Ingår i Frontiers in Immunology, 2021

• DOI för Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength
• Ladda ner fulltext (pdf) av Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength

Regulatory effects of RNA-protein interactions revealed by reporter assays of bacteria grown on solid media

Pérez-Ropero, Guillermo; Dolcemascolo, Roswitha; Pérez-Ràfols, Anna; Andersson, Karl et al.

Ingår i Biosensors, 2025

• DOI för Regulatory effects of RNA-protein interactions revealed by reporter assays of bacteria grown on solid media
• Ladda ner fulltext (pdf) av Regulatory effects of RNA-protein interactions revealed by reporter assays of bacteria grown on solid media

Unraveling the Bivalent and Rapid Interactions Between a Multivalent RNA Recognition Motif and RNA: A Kinetic Approach

Pérez-Ropero, Guillermo; Perez-Rafols, Anna; Martelli, Tommasso; Danielson, U. Helena et al.

Ingår i Biochemistry, s. 2816-2829, 2024

• DOI för Unraveling the Bivalent and Rapid Interactions Between a Multivalent RNA Recognition Motif and RNA: A Kinetic Approach
• Ladda ner fulltext (pdf) av Unraveling the Bivalent and Rapid Interactions Between a Multivalent RNA Recognition Motif and RNA: A Kinetic Approach

Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

Dolcemascolo, Roswitha; Heras-Hernandez, Maria; Goiriz, Lucas; Montagud-Martinez, Roser et al.

Ingår i eLIFE, 2024

• DOI för Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria
• Ladda ner fulltext (pdf) av Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta

Rofo, Fadi; Buijs, Jos; Falk, Ronny; Honek, Ken et al.

Ingår i Translational Neurodegeneration, 2021

• DOI för Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta
• Ladda ner fulltext (pdf) av Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta

Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength

Bondza, Sina; Marosan, Anita; Kara, Sibel; Loesing, Josephine et al.

Ingår i Frontiers in Immunology, 2021

• DOI för Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength
• Ladda ner fulltext (pdf) av Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength

A real-time cell-binding assay reveals dynamic features of STxB-Gb3 cointernalization and STxB-mediated cargo delivery into cancer cells

Encarnacao, Joao Crispim; Napolitano, Valeria; Opassi, Giulia; Danielson, U. Helena et al.

Ingår i FEBS Letters, s. 2406-2420, 2020

• DOI för A real-time cell-binding assay reveals dynamic features of STxB-Gb3 cointernalization and STxB-mediated cargo delivery into cancer cells
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Carbon Flux as a Measure of Prostate Cancer Aggressiveness: [¹¹C]-Acetate PET/CT

Regula, Naresh; Honarvar, Hadis; Lubberink, Mark; Jorulf, Håkan et al.

Ingår i International Journal of Medical Sciences, s. 214-223, 2020

• DOI för Carbon Flux as a Measure of Prostate Cancer Aggressiveness: [¹¹C]-Acetate PET/CT
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Pilot-scale process for magnetic bead purification of antibodies directly from non-clarified CHO cell culture

Brechmann, Nils A.; Eriksson, Per-Olov; Eriksson, Kristofer; Oscarsson, Sven et al.

Ingår i Biotechnology progress (Print), 2019

• DOI för Pilot-scale process for magnetic bead purification of antibodies directly from non-clarified CHO cell culture
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Comparative Evaluation of Two DARPin Variants: Effect of Affinity, Size, and Label on Tumor Targeting Properties

Deyev, Sergey; Vorobyeva, Anzhelika; Schulga, Alexey; Proshkina, Galina et al.

Ingår i Molecular Pharmaceutics, s. 995-1008, 2019

• DOI för Comparative Evaluation of Two DARPin Variants: Effect of Affinity, Size, and Label on Tumor Targeting Properties

Comparative evaluation of dimeric and monomeric forms of ADAPT scaffold protein for targeting of HER2-expressing tumours

Garousi, Javad; Lindbo, Sarah; Borin, Jesper; von Witting, Emma et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 37-48, 2019

• DOI för Comparative evaluation of dimeric and monomeric forms of ADAPT scaffold protein for targeting of HER2-expressing tumours
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Enhanced protection of the renal vascular endothelium improves early outcome in kidney transplantation: Preclinical investigations in pig and mouse

Nordling, Sofia; Brännström, Johan; Carlsson, Fredrik; Lu, Bo et al.

Ingår i Scientific Reports, 2018

• DOI för Enhanced protection of the renal vascular endothelium improves early outcome in kidney transplantation: Preclinical investigations in pig and mouse
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Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe

Honarvar, Hadis; Calce, Enrica; Doti, Nunzianna; Langella, Emma et al.

Ingår i Scientific Reports, 2018

• DOI för Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe
• Ladda ner fulltext (pdf) av Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe

New insights in Type I and II CD20 antibody mechanisms-of-action with a panel of novel CD20 antibodies

Meyer, Saskia; Evers, Mitchell; Jansen, Johannes H. M.; Buijs, Jos et al.

Ingår i British Journal of Haematology, s. 808-820, 2018

• DOI för New insights in Type I and II CD20 antibody mechanisms-of-action with a panel of novel CD20 antibodies

Radionuclide tumor targeting using ADAPT scaffold proteins: aspects of label positioning and residualizing properties of the label

Lindbo, Sarah; Garousi, Javad; Mitran, Bogdan; Buijs, Jos et al.

Ingår i Journal of Nuclear Medicine, s. 93-99, 2018

• DOI för Radionuclide tumor targeting using ADAPT scaffold proteins: aspects of label positioning and residualizing properties of the label

Real-time Characterization of Antibody Binding to Receptors on Living Immune Cells

Bondza, Sina; Foy, Eleanor; Brooks, Jonathan; Andersson, Karl et al.

Ingår i Frontiers in Immunology, 2017

• DOI för Real-time Characterization of Antibody Binding to Receptors on Living Immune Cells
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Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m

Garousi, Javad; Lindbo, Sarah; Mitran, Bogdan; Buijs, Jos et al.

Ingår i Scientific Reports, 2017

• DOI för Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m
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The use of radiocobalt as a label improves imaging of EGFR using DOTA-conjugated Affibody molecule

Garousi, Javad; Andersson, Ken G.; Dam, Johan H.; Olsen, Birgitte B. et al.

Ingår i Scientific Reports, 2017

• DOI för The use of radiocobalt as a label improves imaging of EGFR using DOTA-conjugated Affibody molecule
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Novel Real-Time Proximity Assay for Characterizing Multiple Receptor Interactions on Living Cells

Bondza, Sina; Björkelund, Hanna; Nestor, Marika; Andersson, Karl et al.

Ingår i Analytical Chemistry, s. 13212-13218, 2017

• DOI för Novel Real-Time Proximity Assay for Characterizing Multiple Receptor Interactions on Living Cells

Comparative evaluation of Affibody molecules for radionuclide imaging of in vivo expression of carbonic anhydrase IX

Garousi, Javad; Honarvar, Hadis; Andersson, Ken G.; Mitran, Bogdan et al.

Ingår i Molecular Pharmaceutics, s. 3676-3687, 2016

• DOI för Comparative evaluation of Affibody molecules for radionuclide imaging of in vivo expression of carbonic anhydrase IX

Surface plasmon resonance biosensing: Approaches for screening and characterising antibodies for food diagnostics

Yakes, B. J.; Buijs, Jos; Elliott, C. T.; Campbell, K.

Ingår i Talanta, s. 55-63, 2016

• DOI för Surface plasmon resonance biosensing: Approaches for screening and characterising antibodies for food diagnostics

Evaluation of Affibody Molecules for Radionuclide Imaging of Carbonic Abhydrase IX Expression In Vivo

Garousi, Javad; Honarvar, Hadis; Andersson, K.; Mitran, Bogdan et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2016

ADAPT, a novel scaffold protein-based probe for radionuclide imaging of molecular targets that are expressed in disseminated cancers

Garousi, Javad; Lindbo, Sarah; Nilvebrant, Johan; Åstrand, Mikael et al.

Ingår i Cancer Research, s. 4364-4371, 2015

• DOI för ADAPT, a novel scaffold protein-based probe for radionuclide imaging of molecular targets that are expressed in disseminated cancers

The use of radiocobalt as a label improves PET imaging of EGFR using DOTA-conjugated affibody molecules

Garousi, Javad; Anderson, K.; Dam, J. H.; Olsen, B. B. et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2015

Bivalent Binding on Cells varies between CD20 Antibodies and is Dose-dependent

Bondza, Sina; ten Broeke, Toine; Nestor, Marika; Leusen, Jeanette et al.

Degree of Bivalent Binding correlates with C1q Binding Strength for CD20 Antibodies Rituximab, Ofatumumab, and Obinituzumab.

Bondza, Sina; Buijs, Jos

Deciphering the RNA recognition by Musashi-1 to design protein and RNA mutants for in vitro and in vivo applications

Pérez-Ràfols, Anna; Pérez-Ropero, Guillermo; Cerofolini, Linda; Sperotto, Luca et al.

• DOI för Deciphering the RNA recognition by Musashi-1 to design protein and RNA mutants for in vitro and in vivo applications

Exploring real-time interaction analysis to monitor CD44 expression modulation in cancer cells by inhibiting Musashi-1 interactions with RNA

Pérez-Ropero, Guillermo; Ortstad, Nathalie; Nestor, Marika; Danielson, Helena et al.