Antonia Kalushkova Nair

PVT1 interacts with the polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma

Nylund, Patrick; Garrido-Zabala, Berta; Atienza Párraga, Alba; Vasquez, Louella et al.

Ingår i Haematologica, s. 567-577, 2024

• DOI för PVT1 interacts with the polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma
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The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma

Nylund, Patrick; Garrido-Zabala, Berta; Kalushkova, Antonia; Jernberg Wiklund, Helena

Ingår i Frontiers in Oncology, 2023

• DOI för The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma
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Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Borgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao et al.

Ingår i Cancer Research, s. 4586-4603, 2022

• DOI för Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
• Ladda ner fulltext (pdf) av Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies

Kalushkova, Antonia; Nylund, Patrick; Atienza Párraga, Alba; Lennartsson, Andreas et al.

Ingår i EPIGENOMES, 2021

• DOI för One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies
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A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

Nylund, Patrick; Atienza Párraga, Alba; Haglöf, Jakob; De Bruyne, Elke et al.

Ingår i Cell Death and Disease, 2021

• DOI för A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
• Ladda ner fulltext (pdf) av A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

PVT1 interacts with the polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma

Nylund, Patrick; Garrido-Zabala, Berta; Atienza Párraga, Alba; Vasquez, Louella et al.

Ingår i Haematologica, s. 567-577, 2024

• DOI för PVT1 interacts with the polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma
• Ladda ner fulltext (pdf) av PVT1 interacts with the polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Borgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao et al.

Ingår i Cancer Research, s. 4586-4603, 2022

• DOI för Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
• Ladda ner fulltext (pdf) av Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies

Kalushkova, Antonia; Nylund, Patrick; Atienza Párraga, Alba; Lennartsson, Andreas et al.

Ingår i EPIGENOMES, 2021

• DOI för One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies
• Ladda ner fulltext (pdf) av One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies

A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

Nylund, Patrick; Atienza Párraga, Alba; Haglöf, Jakob; De Bruyne, Elke et al.

Ingår i Cell Death and Disease, 2021

• DOI för A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
• Ladda ner fulltext (pdf) av A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

GMYC: A Novel Inducible Transgenic Model of Group 3 Medulloblastoma

Weishaupt, Holger; Mainwaring, Oliver; Hutter, Sonja; Kalushkova, Antonia et al.

Ingår i Neuro-Oncology, s. 137-137, 2018

• DOI för GMYC: A Novel Inducible Transgenic Model of Group 3 Medulloblastoma

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions.

Alzrigat, Mohammad; Párraga, Alba Atienza; Agarwal, Prasoon; Zureigat, Hadil et al.

Ingår i Oncotarget, s. 10213-10224, 2017

• DOI för EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions.
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The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomain

Alzrigat, Mohammad; Párraga, Alba Atienza; Majumder, Muntasir; Ma, Anqi et al.

Ingår i Oncotarget, s. 103731-103743, 2017

• DOI för The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomain
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Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.

Agarwal, Prasoon; Alzrigat, Mohammad; Párraga, Alba Atienza; Enroth, Stefan et al.

Ingår i Oncotarget, s. 6809-6923, 2016

• DOI för Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.

A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment

Zaghlool, Ammar; Halvardson, Jonatan; Zhao, Jin J.; Etemadikhah, Mitra et al.

Ingår i Human Mutation, s. 964-975, 2016

• DOI för A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment
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Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia

Mansouri, Larry; Sutton, Lesley-Ann; Ljungström, Viktor; Bondza, Sina et al.

Ingår i Journal of Experimental Medicine, s. 833-843, 2015

• DOI för Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
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Recurrent Mutations within the Nfkbie gene: A Novel Mechanism for NF-kappa B Deregulation in Aggressive Chronic Lymphocytic Leukemia

Mansouri, Larry; Sutton, Lesley-Ann; Ljungström, Viktor; Bondza, Sina et al.

Ingår i Blood, 2014

AKN-028 induces cell cycle arrest, downregulation of Myc associated genes and a dose dependent reduction of kinase activity in acute myeloid leukemia

Eriksson, Anna; Kalushkova, Antonia; Jarvius, Malin; Hilhorst, Riet et al.

Ingår i Biochemical Pharmacology, s. 284-291, 2014

• DOI för AKN-028 induces cell cycle arrest, downregulation of Myc associated genes and a dose dependent reduction of kinase activity in acute myeloid leukemia
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An Epigenomic Map of Multiple Myeloma Reveals the Importance of Polycomb Gene Silencing for the Malignancy

Agarwal, Prasoon; Kalushkova, Antonia; Enroth, Stefan; Alzrigat, Mohammad et al.

Ingår i Blood, 2014

Dormant SOX9-positive cells behind MYC-driven medulloblastoma recurrence

Bolin, Sara; Borgenvik, Anna; Savov, Vasil; Holmberg Olausson, Karl et al.

The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma

Nylund, Patrick; Garrido-Zabala, Berta; Kalushkova, Antonia; Jernberg Wiklund, Helena

Ingår i Frontiers in Oncology, 2023

• DOI för The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma
• Ladda ner fulltext (pdf) av The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma

Epigenetic gene regulation in multiple myeloma and mood disorders

Kalushkova, Antonia

2013

• Ladda ner fulltext (pdf) av Epigenetic gene regulation in multiple myeloma and mood disorders

The epigenomic map of multiple myeloma reveals the importance of Polycomb gene silencing for the malignancy

Agarwal, Prasoon; Kalushkova, Antonia; Enroth, Stefan; Österborg, Anders et al.