Gunnar Nilsson

IgE-activated human lung mast cells preferentially release prostaglandin D2 , thromboxane A2 , and cysteinyl-leukotrienes

Johnsson, Anna-Karin; Kolmert, Johan; Ronnberg, Elin; Safholm, Jesper et al.

Ingår i Journal of Allergy and Clinical Immunology, s. 1669-1678, 2025

• DOI för IgE-activated human lung mast cells preferentially release prostaglandin D2 , thromboxane A2 , and cysteinyl-leukotrienes
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Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden)

Bergström, Anna; Hägglund, Hans; Berglund, Anders; Nilsson, Gunnar et al.

Ingår i Acta Dermato-Venereologica, 2025

• DOI för Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden)
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Allergic airway inflammation amplifies mast cell responses in isolated guinea pig intralobular bronchi

Nie, Mu; Liu, Jielu; Xiang, Yujiao; Wong, Anthony et al.

Ingår i American Journal of Physiology - Lung cellular and Molecular Physiology, 2025

• DOI för Allergic airway inflammation amplifies mast cell responses in isolated guinea pig intralobular bronchi
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Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression

Wicher, Grzegorz; Roy, Ananya; Vaccaro, Alessandra; Vemuri, Kalyani et al.

Ingår i Neuro-Oncology Advances, 2025

• DOI för Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression
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Toll-like receptor activation induces airway obstruction and hyperresponsiveness in guinea pigs

Xiang, Yujiao; Liu, Jielu; Nie, Mu; Nilsson, Gunnar et al.

Ingår i Respiratory Research, 2024

• DOI för Toll-like receptor activation induces airway obstruction and hyperresponsiveness in guinea pigs
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IgE-activated human lung mast cells preferentially release prostaglandin D2 , thromboxane A2 , and cysteinyl-leukotrienes

Johnsson, Anna-Karin; Kolmert, Johan; Ronnberg, Elin; Safholm, Jesper et al.

Ingår i Journal of Allergy and Clinical Immunology, s. 1669-1678, 2025

• DOI för IgE-activated human lung mast cells preferentially release prostaglandin D2 , thromboxane A2 , and cysteinyl-leukotrienes
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Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden)

Bergström, Anna; Hägglund, Hans; Berglund, Anders; Nilsson, Gunnar et al.

Ingår i Acta Dermato-Venereologica, 2025

• DOI för Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden)
• Ladda ner fulltext (pdf) av Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden)

Allergic airway inflammation amplifies mast cell responses in isolated guinea pig intralobular bronchi

Nie, Mu; Liu, Jielu; Xiang, Yujiao; Wong, Anthony et al.

Ingår i American Journal of Physiology - Lung cellular and Molecular Physiology, 2025

• DOI för Allergic airway inflammation amplifies mast cell responses in isolated guinea pig intralobular bronchi
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Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression

Wicher, Grzegorz; Roy, Ananya; Vaccaro, Alessandra; Vemuri, Kalyani et al.

Ingår i Neuro-Oncology Advances, 2025

• DOI för Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression
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Toll-like receptor activation induces airway obstruction and hyperresponsiveness in guinea pigs

Xiang, Yujiao; Liu, Jielu; Nie, Mu; Nilsson, Gunnar et al.

Ingår i Respiratory Research, 2024

• DOI för Toll-like receptor activation induces airway obstruction and hyperresponsiveness in guinea pigs
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Plasma Protein Profiling to Discern Indolent from Advanced Systemic Mastocytosis

Iribarren, Cristina; Levedahl, Kerstin; Atanasoai, Ionut; Mattsson, Mattias et al.

Ingår i Journal of Molecular Diagnostics, s. 792-804, 2024

• DOI för Plasma Protein Profiling to Discern Indolent from Advanced Systemic Mastocytosis
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CRISPR/Cas9-mediated gene disruption determines the roles of MITF and CITED2 in human mast cell differentiation

Mo, Jiezhen; Wermeling, Fredrik; Nilsson, Gunnar; Dahlin, Joakim S.

Ingår i Blood Advances, s. 3941-3945, 2024

• DOI för CRISPR/Cas9-mediated gene disruption determines the roles of MITF and CITED2 in human mast cell differentiation
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An optimized method for IgE-mediated degranulation of human lung mast cells

Gong, Yitao; Johnsson, Anna-Karin; Säfholm, Jesper; Al-Ameri, Mamdoh et al.

Ingår i Frontiers in Immunology, 2024

• DOI för An optimized method for IgE-mediated degranulation of human lung mast cells
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Systemic mastocytosis: dying or survivin

Dahlin, Joakim S.; Nilsson, Gunnar

Ingår i Blood, s. 945-947, 2024

• DOI för Systemic mastocytosis: dying or survivin

European Competence Network on Mastocytosis (ECNM): 20-Year Jubilee, Updates, and Future Perspectives

Valent, Peter; Hartmann, Karin; Bonadonna, Patrizia; Sperr, Wolfgang et al.

Ingår i Journal of Allergy and Clinical Immunology, s. 1706-1717, 2023

• DOI för European Competence Network on Mastocytosis (ECNM): 20-Year Jubilee, Updates, and Future Perspectives
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Analysis of human lung mast cells by single cell RNA sequencing

Ronnberg, Elin; Ravindran, Avinash; Mazzurana, Luca; Gong, Yitao et al.

Ingår i Frontiers in Immunology, 2023

• DOI för Analysis of human lung mast cells by single cell RNA sequencing
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Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity

Ronnberg, Elin; Boey, Daryl Zhong Hao; Ravindran, Avinash; Safholm, Jesper et al.

Ingår i Frontiers in Immunology, 2022

• DOI för Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity
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Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors

Wu, Chenyan; Boey, Daryl; Bril, Oscar; Grootens, Jennine et al.

Ingår i Blood Advances, s. 4439-4449, 2022

• DOI för Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors

Charting hematopoiesis in the single-cell omics era

Boey, Daryl; Nilsson, Gunnar; Dahlin, Joakim S.

Ingår i Journal of Allergy and Clinical Immunology, s. 785-787, 2022

• DOI för Charting hematopoiesis in the single-cell omics era

Mast cells derived from systemic mastocytosis exhibit an increased responsiveness to hyperosmolarity

Lyberg, Katarina; Ekoff, Maria; Westerberg, Christine Moller; Engblom, Camilla et al.

Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 1909-1911, 2022

• DOI för Mast cells derived from systemic mastocytosis exhibit an increased responsiveness to hyperosmolarity
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Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction

Tang, Xiao; Ronnberg, Elin; Safholm, Jesper; Thulasingam, Madhuranayaki et al.

Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 2677-2687, 2022

• DOI för Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction
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Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models

Liu, Jielu; Nie, Mu; Dong, Caijuan; Säfholm, Jesper et al.

Ingår i Scientific Reports, 2022

• DOI för Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models
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Graft-versus-Mastocytosis Effect After Donor Lymphocyte Infusion: Proof of Principle.

Hägglund, Hans; Selim Yavuz, Akif; Dreimane, Arta; Malm, Claes et al.

Ingår i European Journal of Haematology, s. 290-293, 2021

• DOI för Graft-versus-Mastocytosis Effect After Donor Lymphocyte Infusion: Proof of Principle.
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Selective inhibition of prostaglandin D-2 biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences

Johnsson, Anna-Karin; Choi, Jeong-Hee; Ronnberg, Elin; Fuchs, David et al.

Ingår i Clinical and Experimental Allergy, s. 594-603, 2021

• DOI för Selective inhibition of prostaglandin D-2 biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences
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Distinct effects of antigen and Compound 48/80 in the guinea pig trachea

Liu, Jielu; Kolmert, Johan; Säfholm, Jesper; Johnsson, Anna-Karin et al.

Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 2270-2273, 2021

• DOI för Distinct effects of antigen and Compound 48/80 in the guinea pig trachea
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COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells

Johnsson, Anna-Karin; Rönnberg, Elin; Fuchs, David; Kolmert, Johan et al.

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2021

• DOI för COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells

Distinct plasma biomarkers confirm the diagnosis of mastocytosis and identify increased risk of anaphylaxis

Gülen, Theo; Teufelberger, Andrea; Ekoff, Maria; Westerberg, Christine Möller et al.

Ingår i Journal of Allergy and Clinical Immunology, s. 889-894, 2021

• DOI för Distinct plasma biomarkers confirm the diagnosis of mastocytosis and identify increased risk of anaphylaxis

CD203c distinguishes the erythroid and mast cell-basophil differentiation trajectories among human Fc epsilon RI+ bone marrow progenitors

Grootens, Jennine; Ungerstedt, Johanna S.; Wu, Chenyan; Levedahl, Kerstin et al.

Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 211-214, 2020

• DOI för CD203c distinguishes the erythroid and mast cell-basophil differentiation trajectories among human Fc epsilon RI+ bone marrow progenitors
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Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium

Hallgren, Jenny; Hellman, Lars; Maurer, Marcus; Nilsson, Gunnar P. et al.

Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 707-708, 2020

• DOI för Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium
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Divergent Effects of Acute and Prolonged Interleukin 33 Exposure on Mast Cell IgE-Mediated Functions

Rönnberg, Elin; Ghaib, Avan; Ceriol, Carlos; Enoksson, Mattias et al.

Ingår i Frontiers in Immunology, 2019

• DOI för Divergent Effects of Acute and Prolonged Interleukin 33 Exposure on Mast Cell IgE-Mediated Functions
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Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis

Grootens, Jennine; Ungerstedt, Johanna S.; Ekoff, Maria; Rönnberg, Elin et al.

Ingår i EBioMedicine, s. 150-158, 2019

• DOI för Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis
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Wnt-3a Induces Cytokine Release in Human Mast Cells

Tebroke, Julia; Lieverse, Joris E.; Säfholm, Jesper; Schulte, Gunnar et al.

Ingår i Cells, 2019

• DOI för Wnt-3a Induces Cytokine Release in Human Mast Cells
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Cytokine-induced endogenous production of prostaglandin D-2 is essential for human group 2 innate lymphoid cell activation

Maric, Jovana; Ravindran, Avinash; Mazzurana, Luca; Van Acker, Aline et al.

Ingår i Journal of Allergy and Clinical Immunology, s. 2202-221400000, 2019

• DOI för Cytokine-induced endogenous production of prostaglandin D-2 is essential for human group 2 innate lymphoid cell activation

New insights into the origin of mast cells

Nilsson, Gunnar; Dahlin, Joakim S.

Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 844-845, 2019

• DOI för New insights into the origin of mast cells

An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells

Ravindran, Avinash; Rönnberg, Elin; Dahlin, Joakim S.; Mazzurana, Luca et al.

Ingår i Frontiers in Immunology, 2018

• DOI för An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells
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Mast cell dependent IL-33/ST2 signaling is protective against the development of airway hyperresponsiveness in a house dust mite mouse model of asthma

Zoltowska Nilsson, Anna Maria; Lei, Ying; Adner, Mikael; Nilsson, G P

Ingår i American Journal of Physiology - Lung cellular and Molecular Physiology, 2018

• DOI för Mast cell dependent IL-33/ST2 signaling is protective against the development of airway hyperresponsiveness in a house dust mite mouse model of asthma

Changing the threshold-Signals and mechanisms of mast cell priming

Halova, Ivana; Rönnberg, Elin; Draberova, Lubica; Vliagoftis, Harissios et al.

Ingår i Immunological Reviews, s. 73-86, 2018

• DOI för Changing the threshold-Signals and mechanisms of mast cell priming

Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis.

Lyberg, Katarina; Ali, Hani Abdulkadir; Grootens, Jennine; Kjellander, Matilda et al.

Ingår i Oncotarget, s. 9647-9659, 2017

• DOI för Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis.
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Interleukin 33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma

Sjöberg, L C; Nilsson, A Zoltowska; Lei, Y; Gregory, J A et al.

Ingår i Scientific Reports, 2017

• DOI för Interleukin 33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma

KIT signaling is dispensable for human mast cell progenitor development

Dahlin, Joakim S.; Ekoff, Maria; Grootens, Jennine; Löf, Liza et al.

Ingår i Blood, s. 1785-1794, 2017

• DOI för KIT signaling is dispensable for human mast cell progenitor development

Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury

Wicher, Grzegorz K.; Wallenquist, Ulrika; Lei, Ying; Enoksson, Mattias et al.

Ingår i Journal of Neurotrauma, s. 3173-3182, 2017

• DOI för Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury

Curdlan induces selective mast cell degranulation without concomitant release of LTC_4, IL-6 or CCL2

Barbosa-Lorenzi, Valéria C; Peyda, Simon; Scheynius, Annika; Nilsson, Gunnar et al.

Ingår i Immunobiology, s. 647-650, 2017

• DOI för Curdlan induces selective mast cell degranulation without concomitant release of LTC_4, IL-6 or CCL2

Assessment of in vivo mast cell reactivity in patients with systemic mastocytosis.

Gülen, T; Möller Westerberg, C; Lyberg, K; Ekoff, M et al.

Ingår i Clinical and Experimental Allergy, s. 909-917, 2017

• DOI för Assessment of in vivo mast cell reactivity in patients with systemic mastocytosis.

Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.

Valent, Peter; Akin, Cem; Hartmann, Karin; Nilsson, Gunnar et al.

Ingår i Cancer Research, s. 1261-1270, 2017

• DOI för Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.

Risk Factor Analysis of Anaphylactic Reactions in Patients With Systemic Mastocytosis.

Gülen, Theo; Ljung, Christopher; Nilsson, Gunnar; Akin, Cem

Ingår i Journal of Allergy and Clinical Immunology, s. 1248-1255, 2017

• DOI för Risk Factor Analysis of Anaphylactic Reactions in Patients With Systemic Mastocytosis.

Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology

Hartmann, Karin; Escribano, Luis; Grattan, Clive; Brockow, Knut et al.

Ingår i Journal of Allergy and Clinical Immunology, s. 35-45, 2016

• DOI för Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology

Multidisciplinary Management of Mastocytosis: Nordic Expert Group Consensus

Broesby-Olsen, Sigurd; Dybedal, Ingunn; Gülen, Theo; Kielsgaard Kristensen, Thomas et al.

Ingår i Acta Dermato-Venereologica, 2016

• DOI för Multidisciplinary Management of Mastocytosis: Nordic Expert Group Consensus

Detection of circulating mast cells in advanced systemic mastocytosis

Dahlin, J. S.; Ungerstedt, J. S.; Grootens, J.; Sander, B. et al.

Ingår i Leukemia, s. 1954-+, 2016

• DOI för Detection of circulating mast cells in advanced systemic mastocytosis

Increased risk of malignant melanoma in patients with systemic mastocytosis?

Hägglund, Hans; Sander, Birgitta; Gülen, Theo; Lindelöf, Bernt et al.

Ingår i Acta Dermato-Venereologica, s. 583-584, 2014

• DOI för Increased risk of malignant melanoma in patients with systemic mastocytosis?

The presence of mast cell clonality in patients with unexplained anaphylaxis

Gülen, T; Hägglund, Hans; Sander, B; Dahlén, B et al.

Ingår i Clinical and Experimental Allergy, s. 1179-1187, 2014

• DOI för The presence of mast cell clonality in patients with unexplained anaphylaxis

Flushing, fatigue, and recurrent anaphylaxis: a delayed diagnosis of mastocytosis

Gülen, Theo; Hägglund, Hans; Dahlén, Sven-Erik; Sander, Birgitta et al.

Ingår i The Lancet, s. 1608, 2014

• DOI för Flushing, fatigue, and recurrent anaphylaxis: a delayed diagnosis of mastocytosis

Interleukin-15 + thioredoxin induce DNA synthesis in B-chronic lymphocytic leukemia cells but not in normal B cells.

Söderberg, O; Christiansen, I; Nilsson, G; Carlsson, M et al.

Ingår i Leukemia, s. 1298-304, 1997

Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells

Grootens, Jennine; Ungerstedt, Johanna S.; Nilsson, Gunnar; Dahlin, Joakim S.

Ingår i Blood Advances, s. 2273-2281, 2018

• DOI för Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells

Positive and Negative Signals in Mast Cell Activation

Bulfone-Paus, Silvia; Nilsson, Gunnar; Draber, Petr; Blank, Ulrich et al.

Ingår i Trends in immunology, s. 657-667, 2017

• DOI för Positive and Negative Signals in Mast Cell Activation

Mastocytosis: the puzzling clinical spectrum and challenging diagnostic aspects of an enigmatic disease

Gülen, T; Hägglund, Hans; Dahlén, B; Nilsson, Gunnar

Ingår i Journal of Internal Medicine, s. 211-228, 2016

• DOI för Mastocytosis: the puzzling clinical spectrum and challenging diagnostic aspects of an enigmatic disease