Robert Fredriksson

The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation

Hellsten, Sofie V.; Lekholm, Emilia; Ahmad, Tauseef; Fredriksson, Robert

Ingår i FEBS Open Bio, s. 249-264, 2017

• DOI för The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation
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Classification Systems of Secondary Active Transporters

Perland, Emelie; Fredriksson, Robert

Ingår i TIPS - Trends in Pharmacological Sciences, s. 305-315, 2017

• DOI för Classification Systems of Secondary Active Transporters

The neuronal and astrocytic protein SLC38A10 transports glutamine, glutamate, and aspartate, suggesting a role in neurotransmission

Hellsten, Sofie V.; Hägglund, Maria; Eriksson, Mikaela; Fredriksson, Robert

Ingår i FEBS Open Bio, s. 730-746, 2017

• DOI för The neuronal and astrocytic protein SLC38A10 transports glutamine, glutamate, and aspartate, suggesting a role in neurotransmission
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Characteristics of 29 novel atypical SLCs of MFS type: evolutionary conservation, predicted structure and neuronal co-expression

Perland, Emelie; Bagchi, Sonchita; Klaesson, Axel; Fredriksson, Robert

Ingår i Open Biology, 2017

• DOI för Characteristics of 29 novel atypical SLCs of MFS type: evolutionary conservation, predicted structure and neuronal co-expression
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The gene expression of the neuronal protein, SLC38A9, changes in mouse brain after in vivo starvation and high-fat diet

Hellsten, Sofie V.; Eriksson, Mikaela; Lekholm, Emilia; Arapi, Vasiliki et al.

Ingår i PLOS ONE, 2017

• DOI för The gene expression of the neuronal protein, SLC38A9, changes in mouse brain after in vivo starvation and high-fat diet
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A Combinatorial Approach to Induce Sensory Axon Regeneration into the Dorsal Root Avulsed Spinal Cord

Hoeber, Jan; König, Niclas; Trolle, Carl; Lekholm, Emilia et al.

Ingår i Stem Cells and Development, s. 1065-1077, 2017

• DOI för A Combinatorial Approach to Induce Sensory Axon Regeneration into the Dorsal Root Avulsed Spinal Cord

Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability

Lekholm, Emilia; Perland, Emelie; Eriksson, Mikaela M.; Hellsten, Sofie V. et al.

Ingår i Frontiers in Molecular Neuroscience, 2017

• DOI för Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability
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The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake

Perland, Emelie; Hellsten, Sofie V.; Lekholm, Emilia; Eriksson, Mikaela M. et al.

Ingår i Journal of Molecular Neuroscience, s. 199-214, 2017

• DOI för The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake
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Characterization of a unique amino acid transporter, SNAT10, in the Golgi apparatus

Bagchi, Sonchita; Hellsten, Sofie Victora; Hägglund, Maria; Arapi, Vasiliki et al.

2016

Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney

Roshanbin, Sahar; Lindberg, Frida; Lekholm, Emilia; Perland, Emelie et al.

Ingår i BMC Neuroscience, 2016

• DOI för Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney
• Ladda ner fulltext (pdf) av Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney

The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder

Williams, Michael; Klockars, Anica; Eriksson, Anders; Voisin, Sarah et al.

Ingår i PLOS Genetics, 2016

• DOI för The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder
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The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis

Perland, Emelie; Lekholm, Emilia; Eriksson, Mikaela M.; Bagchi, Sonchita et al.

Ingår i PLOS ONE, 2016

• DOI för The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis
• Ladda ner fulltext (pdf) av The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis

Amino acid deprivation of neuronal cells changes expression levels of numerous transporters from the SLC family, including several members of the SLC38 family

Hellsten, Sofie Victora; Perland, Emelie; Lekholm, Emilia; Ahmad, Tauseef et al.

2016

The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

Wiemerslage, Lyle; Gohel, Priya A.; Maestri, Giulia; Hilmarsson, Torfi G. et al.

Ingår i Journal of Endocrinology, s. 233-243, 2016

• DOI för The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

Transport of L-glutamine, L-alanine, L-arginine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS

Hägglund, Maria G A; Hellsten, Sofie V; Bagchi, Sonchita; Philippot, Gaëtan et al.

Ingår i Journal of Molecular Biology, s. 1495-1512, 2015

• DOI för Transport of L-glutamine, L-alanine, L-arginine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS

In Situ Proximity Ligation Assay (PLA)

Bagchi, Sonchita; Fredriksson, Robert; Wallén-Mackenzie, Åsa

Ingår i ELISA, s. 149-159, Springer-Verlag New York, 2015

• DOI för In Situ Proximity Ligation Assay (PLA)

Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster

Williams, Michael; Goergen, Philip; Rajendran, Jayasimman; Zheleznyakova, Galina et al.

Ingår i PLOS Genetics, 2014

• DOI för Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster
• Ladda ner fulltext (pdf) av Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster

Histological Analysis of SLC38A6 (SNAT6) Expression in Mouse Brain Shows Selective Expression in Excitatory Neurons with High Expression in the Synapses

Bagchi, Sonchita; Baomar, Hajar Ali; Al-Walai, Somar; Al-Sadi, Saifaddin et al.

Ingår i PLOS ONE, 2014

• DOI för Histological Analysis of SLC38A6 (SNAT6) Expression in Mouse Brain Shows Selective Expression in Excitatory Neurons with High Expression in the Synapses
• Ladda ner fulltext (pdf) av Histological Analysis of SLC38A6 (SNAT6) Expression in Mouse Brain Shows Selective Expression in Excitatory Neurons with High Expression in the Synapses

PAT4 is abundantly expressed in excitatory and inhibitory neurons as well as epithelial cells

Roshanbin, Sahar; Hellsten, Sofie V; Tafreshiha, Atieh; Zhu, Yinan et al.

Ingår i Brain Research, s. 12-25, 2014

• DOI för PAT4 is abundantly expressed in excitatory and inhibitory neurons as well as epithelial cells
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The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour

Williams, Michael J.; Goergen, Philip; Phad, Ganesh; Fredriksson, Robert et al.

Ingår i European Journal of Neuroscience, s. 2513-2526, 2014

• DOI för The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour

Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

Williams, Michael J; Goergen, Philip; Rajendran, Jayasimman; Klockars, Anica et al.

Ingår i Genetics, s. 349-362, 2014

• DOI för Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system

Hägglund, Maria G. A.; Hellsten, Sofie V.; Bagchi, Sonchita; Ljungdahl, Anna et al.

Ingår i BMC Neuroscience, s. 54, 2013

• DOI för Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system
• Ladda ner fulltext (pdf) av Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system

Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes

Drgonova, Jana; Jacobsson, Josefin A.; Han, Joan C.; Yanovski, Jack A. et al.

Ingår i PLOS ONE, 2013

• DOI för Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes
• Ladda ner fulltext (pdf) av Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes

B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain

Hägglund, Maria G A; Roshanbin, Sahar; Löfqvist, Erik; Hellsten, Sofie V et al.

Ingår i PLOS ONE, 2013

• DOI för B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain
• Ladda ner fulltext (pdf) av B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain

G Protein-Coupled Receptor Deorphanizations

Civelli, Olivier; Reinscheid, Rainer K; Zhang, Yan; Wang, Zhiwei et al.

Ingår i Annual Review of Pharmacology and Toxicology, s. 127-146, 2013

• DOI för G Protein-Coupled Receptor Deorphanizations

Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

Schiöth, Helgi B; Roshanbin, Sahar; Hägglund, Maria G A; Fredriksson, Robert

Ingår i Molecular Aspects of Medicine, s. 571-585, 2013

• DOI för Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

Solute carriers as drug targets: current use, clinical trials and prospective

Rask-Andersen, Mathias; Masuram, Surendar; Fredriksson, Robert; Schiöth, Helgi B

Ingår i Molecular Aspects of Medicine, s. 702-710, 2013

• DOI för Solute carriers as drug targets: current use, clinical trials and prospective

The evolutionary history and tissue mapping of amino acid transporters belonging to solute carrier families SLC32, SLC36, and SLC38

Sundberg, Björn E; Wååg, Elin; Jacobsson, Josefin A; Stephansson, Olga et al.

Ingår i Journal of Molecular Neuroscience, s. 179-193, 2008

• DOI för The evolutionary history and tissue mapping of amino acid transporters belonging to solute carrier families SLC32, SLC36, and SLC38

Boundary cap neural crest stem cells exhibit remarkable resilience to environmental stressors associated with International Space Station mission

Fredriksson, Robert; Han, Yilin; Du, Xiangyi; Sexton, Craig A. et al.

Ingår i npj Microgravity, 2026

• DOI för Boundary cap neural crest stem cells exhibit remarkable resilience to environmental stressors associated with International Space Station mission
• Ladda ner fulltext (pdf) av Boundary cap neural crest stem cells exhibit remarkable resilience to environmental stressors associated with International Space Station mission

Transcriptomic meta-analysis identifies dysregulated pathways and potential therapeutic targets in Vestibular Schwannoma

Altinalan, Ebrar; Panina, Aleksandra; Fredriksson, Robert; Sakul, Ayse Arzu et al.

Ingår i PLOS ONE, 2026

• DOI för Transcriptomic meta-analysis identifies dysregulated pathways and potential therapeutic targets in Vestibular Schwannoma
• Ladda ner fulltext (pdf) av Transcriptomic meta-analysis identifies dysregulated pathways and potential therapeutic targets in Vestibular Schwannoma

Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults

Good, Linnéa; Mateus Brandão, Luiz Eduardo; van Egmond, Lieve Thecla; Khoonsari, Payam Emami et al.

Ingår i Journal of Translational Medicine, 2026

• DOI för Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults
• Ladda ner fulltext (pdf) av Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults

Associations of PYY, GLP-1 and LEAP2 with changes in feeding-related cognition, body weight and glucose homeostasis after bariatric surgery in non-diabetic women

Andreoli, María Florencia; De Francesco, Pablo N.; Zhou, Wei; Titova, Olga et al.

Ingår i Journal of neuroendocrinology, 2026

• DOI för Associations of PYY, GLP-1 and LEAP2 with changes in feeding-related cognition, body weight and glucose homeostasis after bariatric surgery in non-diabetic women
• Ladda ner fulltext (pdf) av Associations of PYY, GLP-1 and LEAP2 with changes in feeding-related cognition, body weight and glucose homeostasis after bariatric surgery in non-diabetic women

Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood

Panina, Aleksandra; Sokolov, Aleksandr V.; Jonsson, Jörgen; Fredriksson, Robert et al.

Ingår i Neurobiology of Disease, 2026

• DOI för Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood
• Ladda ner fulltext (pdf) av Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood

Boundary cap neural crest stem cells exhibit remarkable resilience to environmental stressors associated with International Space Station mission

Fredriksson, Robert; Han, Yilin; Du, Xiangyi; Sexton, Craig A. et al.

Ingår i npj Microgravity, 2026

• DOI för Boundary cap neural crest stem cells exhibit remarkable resilience to environmental stressors associated with International Space Station mission
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Transcriptomic meta-analysis identifies dysregulated pathways and potential therapeutic targets in Vestibular Schwannoma

Altinalan, Ebrar; Panina, Aleksandra; Fredriksson, Robert; Sakul, Ayse Arzu et al.

Ingår i PLOS ONE, 2026

• DOI för Transcriptomic meta-analysis identifies dysregulated pathways and potential therapeutic targets in Vestibular Schwannoma
• Ladda ner fulltext (pdf) av Transcriptomic meta-analysis identifies dysregulated pathways and potential therapeutic targets in Vestibular Schwannoma

Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults

Good, Linnéa; Mateus Brandão, Luiz Eduardo; van Egmond, Lieve Thecla; Khoonsari, Payam Emami et al.

Ingår i Journal of Translational Medicine, 2026

• DOI för Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults
• Ladda ner fulltext (pdf) av Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults

Associations of PYY, GLP-1 and LEAP2 with changes in feeding-related cognition, body weight and glucose homeostasis after bariatric surgery in non-diabetic women

Andreoli, María Florencia; De Francesco, Pablo N.; Zhou, Wei; Titova, Olga et al.

Ingår i Journal of neuroendocrinology, 2026

• DOI för Associations of PYY, GLP-1 and LEAP2 with changes in feeding-related cognition, body weight and glucose homeostasis after bariatric surgery in non-diabetic women
• Ladda ner fulltext (pdf) av Associations of PYY, GLP-1 and LEAP2 with changes in feeding-related cognition, body weight and glucose homeostasis after bariatric surgery in non-diabetic women

Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood

Panina, Aleksandra; Sokolov, Aleksandr V.; Jonsson, Jörgen; Fredriksson, Robert et al.

Ingår i Neurobiology of Disease, 2026

• DOI för Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood
• Ladda ner fulltext (pdf) av Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood

Meta-analysis of blood metabolomics reveals dysregulated amino acid, neurotransmitter, and energy pathways in depression

Panina, Aleksandra; Sokolov, Aleksandr V.; Khandokhin, Mikhail M.; Oskolkov, Nikolay et al.

Ingår i Progress in Neuro-psychopharmacology and Biological Psychiatry, 2026

• DOI för Meta-analysis of blood metabolomics reveals dysregulated amino acid, neurotransmitter, and energy pathways in depression
• Ladda ner fulltext (pdf) av Meta-analysis of blood metabolomics reveals dysregulated amino acid, neurotransmitter, and energy pathways in depression

Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells

Lagunas-Rangel, Francisco Alejandro; Åberg, Martin; Liao, Sifang; Espinelli-Amorim, Felippe et al.

Ingår i Science of the Total Environment, 2025

• DOI för Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells
• Ladda ner fulltext (pdf) av Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells

Statin drugs and lipid modulation: Mechanistic basis considering lipid rafts, kinase signaling, myopathy, and cancer

Karthikeyan, Suditi; Somasundaram, Poornima; Karimi, Isaac; Lagunas-Rangel, Francisco Alejandro et al.

Ingår i Pharmacological Research, 2025

• DOI för Statin drugs and lipid modulation: Mechanistic basis considering lipid rafts, kinase signaling, myopathy, and cancer
• Ladda ner fulltext (pdf) av Statin drugs and lipid modulation: Mechanistic basis considering lipid rafts, kinase signaling, myopathy, and cancer

RelabotulinumtoxinA, a Ready-to-Use Formulation Neuromodulator Manufactured with PEARL^TM Technology to Maintain High Biological and Specific Activity

Ståhl, Ulf; Lekholm, Emilia; Hamnevik, Emil; Fredriksson, Robert et al.

Ingår i Toxins, 2025

• DOI för RelabotulinumtoxinA, a Ready-to-Use Formulation Neuromodulator Manufactured with PEARL^TM Technology to Maintain High Biological and Specific Activity
• Ladda ner fulltext (pdf) av RelabotulinumtoxinA, a Ready-to-Use Formulation Neuromodulator Manufactured with PEARL^TM Technology to Maintain High Biological and Specific Activity

Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer

Lagunas-Rangel, Francisco Alejandro; Jonsson, Jörgen; Jackevica, Ludmila; Fredriksson, Robert et al.

Ingår i Frontiers in Pharmacology, 2025

• DOI för Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer
• Ladda ner fulltext (pdf) av Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer

Transcriptomic characterization of maturing neurons from human neural stem cells across developmental time points

Hosseini, Kimia; Philippot, Gaëtan; Salomonsson, Sara; Cediel Ulloa, Andrea et al.

Ingår i IBRO NEUROSCIENCE REPORTS, s. 679-689, 2025

• DOI för Transcriptomic characterization of maturing neurons from human neural stem cells across developmental time points
• Ladda ner fulltext (pdf) av Transcriptomic characterization of maturing neurons from human neural stem cells across developmental time points

Effects of microgravity on neural crest stem cells

Han, Yilin; Barasa, Povilas; Zeger, Lukas; Salomonsson, Sara B. et al.

Ingår i Frontiers in Neuroscience, 2024

• DOI för Effects of microgravity on neural crest stem cells
• Ladda ner fulltext (pdf) av Effects of microgravity on neural crest stem cells

Assessing the Neurodevelopmental Impact of Fluoxetine, Citalopram, and Paroxetine on Neural Stem Cell-Derived Neurons

Hosseini, Kimia; Cediel Ulloa, Andrea; Al-Sabri, Mohamed H.; Forsby, Anna et al.

Ingår i Pharmaceuticals, 2024

• DOI för Assessing the Neurodevelopmental Impact of Fluoxetine, Citalopram, and Paroxetine on Neural Stem Cell-Derived Neurons
• Ladda ner fulltext (pdf) av Assessing the Neurodevelopmental Impact of Fluoxetine, Citalopram, and Paroxetine on Neural Stem Cell-Derived Neurons

Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases

Lagunas-Rangel, Francisco Alejandro; Liepinsh, Edgars; Fredriksson, Robert; Alsehli, Ahmed M. et al.

Ingår i British Journal of Pharmacology, s. 3799-3818, 2024

• DOI för Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
• Ladda ner fulltext (pdf) av Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases

Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver

Liepinsh, Edgars; Zvejniece, Liga; Clemensson, Laura; Ozola, Melita et al.

Ingår i British Journal of Pharmacology, s. 2750-2773, 2024

• DOI för Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver
• Ladda ner fulltext (pdf) av Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver

Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Ingår i Scientific Reports, 2024

• DOI för Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
• Ladda ner fulltext (pdf) av Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Vesicular glutamate transporter 2 expression in the ventral tegmental area of outbred male rats following exposure to nicotine and alcohol

Vrettou, Maria; Thalhammer, Stefan Bernhard; Dumas, Sylvie; Nilsson, Kent W. et al.

Ingår i DRUG AND ALCOHOL DEPENDENCE REPORTS, 2023

• DOI för Vesicular glutamate transporter 2 expression in the ventral tegmental area of outbred male rats following exposure to nicotine and alcohol
• Ladda ner fulltext (pdf) av Vesicular glutamate transporter 2 expression in the ventral tegmental area of outbred male rats following exposure to nicotine and alcohol

SLC38A10 Deficiency in Mice Affects Plasma Levels of Threonine and Histidine in Males but Not in Females: A Preliminary Characterization Study of SLC38A10(-/-) Mice

Lindberg, Frida A.; Nordenankar, Karin; Forsberg, Erica; Fredriksson, Robert

Ingår i Genes, 2023

• DOI för SLC38A10 Deficiency in Mice Affects Plasma Levels of Threonine and Histidine in Males but Not in Females: A Preliminary Characterization Study of SLC38A10(-/-) Mice
• Ladda ner fulltext (pdf) av SLC38A10 Deficiency in Mice Affects Plasma Levels of Threonine and Histidine in Males but Not in Females: A Preliminary Characterization Study of SLC38A10(-/-) Mice

Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro

Melander, Erik; Eriksson, Camilla; Wellens, Sara; Hosseini, Kimia et al.

Ingår i Pharmaceutics, 2023

• DOI för Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro
• Ladda ner fulltext (pdf) av Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro

Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4

Lagunas-Rangel, Francisco Alejandro; Liao, Sifang; Williams, Michael J.; Trukhan, Vladimir et al.

Ingår i Biomedicines, 2023

• DOI för Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
• Ladda ner fulltext (pdf) av Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4

SLC38A10 knockout mice display a decreased body weight and an increased risk-taking behavior in the open field test

Lindberg, Frida A.; Nordin, Karin; Fredriksson, Robert

Ingår i Frontiers in Behavioral Neuroscience, 2022

• DOI för SLC38A10 knockout mice display a decreased body weight and an increased risk-taking behavior in the open field test
• Ladda ner fulltext (pdf) av SLC38A10 knockout mice display a decreased body weight and an increased risk-taking behavior in the open field test

Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

Al-Sabri, Mohamed H.; Behare, Neha; Alsehli, Ahmed M.; Berkins, Samuel et al.

Ingår i Cells, 2022

• DOI för Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
• Ladda ner fulltext (pdf) av Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

SLC38A10 Regulate Glutamate Homeostasis and Modulate the AKT/TSC2/mTOR Pathway in Mouse Primary Cortex Cells

Tripathi, Rekha; Aggarwal, Tanya; Lindberg, Frida A.; Klemm, Anna H et al.

Ingår i Frontiers in cell and developmental biology, 2022

• DOI för SLC38A10 Regulate Glutamate Homeostasis and Modulate the AKT/TSC2/mTOR Pathway in Mouse Primary Cortex Cells
• Ladda ner fulltext (pdf) av SLC38A10 Regulate Glutamate Homeostasis and Modulate the AKT/TSC2/mTOR Pathway in Mouse Primary Cortex Cells

A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies

Ceder, Mikaela M.; Fredriksson, Robert

Ingår i Gene, 2022

• DOI för A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies
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Paracetamol (Acetaminophen) and its Effect on the Developing Mouse Brain

Philippot, Gaëtan; Hosseini, Kimia; Yakub, Armine; Mhajar, Yasser et al.

Ingår i Frontiers in Toxicology, 2022

• DOI för Paracetamol (Acetaminophen) and its Effect on the Developing Mouse Brain
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The Fly Homologue of MFSD11 Is Possibly Linked to Nutrient Homeostasis and Has a Potential Role in Locomotion: A First Characterization of the Atypical Solute Carrier CG18549 in Drosophila Melanogaster

Ceder, Mikaela M.; Lindberg, Frida A.; Perland, Emelie; Williams, Michael J. et al.

Ingår i Insects, 2021

• DOI för The Fly Homologue of MFSD11 Is Possibly Linked to Nutrient Homeostasis and Has a Potential Role in Locomotion: A First Characterization of the Atypical Solute Carrier CG18549 in Drosophila Melanogaster
• Ladda ner fulltext (pdf) av The Fly Homologue of MFSD11 Is Possibly Linked to Nutrient Homeostasis and Has a Potential Role in Locomotion: A First Characterization of the Atypical Solute Carrier CG18549 in Drosophila Melanogaster

Toll-like receptor 4 methylation grade is linked to depressive symptom severity

Rasmusson, Annica J.; Gallwitz, Maike; Soltanabadi, Bardia; Ciuculete, Diana-Maria et al.

Ingår i Translational Psychiatry, 2021

• DOI för Toll-like receptor 4 methylation grade is linked to depressive symptom severity
• Ladda ner fulltext (pdf) av Toll-like receptor 4 methylation grade is linked to depressive symptom severity

Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine-Glutamate Cycle

Gandasi, Nikhil R.; Arapi, Vasiliki; Mickael, Michel E.; Belekar, Prajakta A. et al.

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine-Glutamate Cycle
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Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival

Lukashina, Nina; Williams, Michael J.; Kartysheva, Elena; Virko, Elizaveta et al.

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival
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Evaluation of the dentate gyrus in adult mice exposed to acetaminophen (paracetamol) on postnatal day 10

Philippot, Gaetan; Hellsten, Sofie V; Viberg, Henrik; Fredriksson, Robert

Ingår i International Journal of Developmental Neuroscience, s. 91-97, 2021

• DOI för Evaluation of the dentate gyrus in adult mice exposed to acetaminophen (paracetamol) on postnatal day 10

Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

Lekholm, Emilia; Ceder, Mikaela M.; Forsberg, Erica C.; Schiöth, Helgi B. et al.

Ingår i Cellular & Molecular Biology Letters (Druk), 2021

• DOI för Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns
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Molecular genetic analysis of neural stem cells after space flight and simulated microgravity on earth

Han, Yilin; Zeger, Lukas; Tripathi, Rekha; Egli, Marcel et al.

Ingår i Biotechnology and Bioengineering, s. 3832-3846, 2021

• DOI för Molecular genetic analysis of neural stem cells after space flight and simulated microgravity on earth
• Ladda ner fulltext (pdf) av Molecular genetic analysis of neural stem cells after space flight and simulated microgravity on earth

SLC38A10 Transporter Plays a Role in Cell Survival Under Oxidative Stress and Glutamate Toxicity

Tripathi, Rekha; Aggarwal, Tanya; Fredriksson, Robert

Ingår i Frontiers in Bioscience, 2021

• DOI för SLC38A10 Transporter Plays a Role in Cell Survival Under Oxidative Stress and Glutamate Toxicity
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Differentiation of Human Embryonic Stem Cells into Neuron, Cholinergic, and Glial Cells

Hosseini, Kimia; Lekholm, Emilia; Ahemaiti, Aikeremu; Fredriksson, Robert

Ingår i Stem Cells International, 2020

• DOI för Differentiation of Human Embryonic Stem Cells into Neuron, Cholinergic, and Glial Cells
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Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster

Ceder, Mikaela M.; Lekholm, Emilia; Klaesson, Axel; Tripathi, Rekha et al.

Ingår i Frontiers in Cell and Developmental Biology, 2020

• DOI för Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster
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Knockdown of SLC38 Transporter Ortholog-CG13743 Reveals a Metabolic Relevance in Drosophila

Aggarwal, Tanya; Patil, Sourabh; Ceder, Mikaela; Hayder, Maher et al.

Ingår i Frontiers in Physiology, 2020

• DOI för Knockdown of SLC38 Transporter Ortholog-CG13743 Reveals a Metabolic Relevance in Drosophila
• Ladda ner fulltext (pdf) av Knockdown of SLC38 Transporter Ortholog-CG13743 Reveals a Metabolic Relevance in Drosophila

Probable role for major facilitator superfamily domain containing 6 (MFSD6) in the brain during variable energy consumption

Bagchi, Sonchita; Perland, Emelie; Hosseini, Kimia; Lundgren, Johanna et al.

Ingår i International Journal of Neuroscience, s. 476-489, 2020

• DOI för Probable role for major facilitator superfamily domain containing 6 (MFSD6) in the brain during variable energy consumption
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CG4928 is vital for renal function in fruit flies and membrane potential in cells: A first in-depth characterization of the putative Solute Carrier UNC93A

Ceder, Mikaela M.; Aggarwal, Tanya; Hosseini, Kimia; Maturi, Varun et al.

Ingår i Frontiers in Cell and Developmental Biology, 2020

• DOI för CG4928 is vital for renal function in fruit flies and membrane potential in cells: A first in-depth characterization of the putative Solute Carrier UNC93A
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A Single delta(9)-Tetrahydrocannabinol (THC) Dose During Brain Development Affects Markers of Neurotrophy, Oxidative Stress, and Apoptosis

Philippot, Gaetan; Forsberg, Erica; Tahan, Caroline; Viberg, Henrik et al.

Ingår i Frontiers in Pharmacology, 2019

• DOI för A Single delta(9)-Tetrahydrocannabinol (THC) Dose During Brain Development Affects Markers of Neurotrophy, Oxidative Stress, and Apoptosis
• Ladda ner fulltext (pdf) av A Single delta(9)-Tetrahydrocannabinol (THC) Dose During Brain Development Affects Markers of Neurotrophy, Oxidative Stress, and Apoptosis

The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.

Fredriksson, Robert; Sreedharan, Smitha; Nordenankar, Karin; Alsiö, Johan et al.

Ingår i PLOS Genetics, 2019

• DOI för The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.
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SLC38A10 (SNAT10) is Located in ER and Golgi Compartments and Has a Role in Regulating Nascent Protein Synthesis.

Tripathi, Rekha; Hosseini, Kimia; Arapi, Vasiliki; Fredriksson, Robert et al.

Ingår i International Journal of Molecular Sciences, 2019

• DOI för SLC38A10 (SNAT10) is Located in ER and Golgi Compartments and Has a Role in Regulating Nascent Protein Synthesis.
• Ladda ner fulltext (pdf) av SLC38A10 (SNAT10) is Located in ER and Golgi Compartments and Has a Role in Regulating Nascent Protein Synthesis.

Nutritional Stress Induced by Amino Acid Starvation Results in Changes for Slc38 Transporters in Immortalized Hypothalamic Neuronal Cells and Primary Cortex Cells

Hellsten, Sofie V; Tripathi, Rekha; Ceder, Mikaela; Fredriksson, Robert

Ingår i Frontiers in Molecular Biosciences, 2018

• DOI för Nutritional Stress Induced by Amino Acid Starvation Results in Changes for Slc38 Transporters in Immortalized Hypothalamic Neuronal Cells and Primary Cortex Cells
• Ladda ner fulltext (pdf) av Nutritional Stress Induced by Amino Acid Starvation Results in Changes for Slc38 Transporters in Immortalized Hypothalamic Neuronal Cells and Primary Cortex Cells

A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol)

Philippot, Gaetan; Hallgren, Stefan; Gordh, Torsten; Fredriksson, Anders et al.

Ingår i Toxicological Sciences, s. 203-212, 2018

• DOI för A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol)
• Ladda ner fulltext (pdf) av A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol)

The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation

Hellsten, Sofie V.; Lekholm, Emilia; Ahmad, Tauseef; Fredriksson, Robert

Ingår i FEBS Open Bio, s. 249-264, 2017

• DOI för The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation
• Ladda ner fulltext (pdf) av The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation

The neuronal and astrocytic protein SLC38A10 transports glutamine, glutamate, and aspartate, suggesting a role in neurotransmission

Hellsten, Sofie V.; Hägglund, Maria; Eriksson, Mikaela; Fredriksson, Robert

Ingår i FEBS Open Bio, s. 730-746, 2017

• DOI för The neuronal and astrocytic protein SLC38A10 transports glutamine, glutamate, and aspartate, suggesting a role in neurotransmission
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Vgluts In The Mesocorticolimbic Brain Of Adolescent Outbred Rats Exposed To Alcohol And Nicotine

Vrettou, Maria; Nordenankar, Karin; Segerström, Lova; Wallén-Mackenzie, Åsa et al.

Ingår i Alcohol and Alcoholism, 2017

Characteristics of 29 novel atypical SLCs of MFS type: evolutionary conservation, predicted structure and neuronal co-expression

Perland, Emelie; Bagchi, Sonchita; Klaesson, Axel; Fredriksson, Robert

Ingår i Open Biology, 2017

• DOI för Characteristics of 29 novel atypical SLCs of MFS type: evolutionary conservation, predicted structure and neuronal co-expression
• Ladda ner fulltext (pdf) av Characteristics of 29 novel atypical SLCs of MFS type: evolutionary conservation, predicted structure and neuronal co-expression

Elevated total plasma-adiponectin is stable over time in young women with bulimia nervosa

Syk, Mikaela; Ramklint, Mia; Fredriksson, Robert; Ekselius, Lisa et al.

Ingår i European psychiatry, s. 30-36, 2017

• DOI för Elevated total plasma-adiponectin is stable over time in young women with bulimia nervosa

Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice

Perland, Emelie; Hellsten, Sofie V; Schweizer, Nadine; Arapi, Vasiliki et al.

Ingår i PLOS ONE, 2017

• DOI för Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice
• Ladda ner fulltext (pdf) av Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice

The gene expression of the neuronal protein, SLC38A9, changes in mouse brain after in vivo starvation and high-fat diet

Hellsten, Sofie V.; Eriksson, Mikaela; Lekholm, Emilia; Arapi, Vasiliki et al.

Ingår i PLOS ONE, 2017

• DOI för The gene expression of the neuronal protein, SLC38A9, changes in mouse brain after in vivo starvation and high-fat diet
• Ladda ner fulltext (pdf) av The gene expression of the neuronal protein, SLC38A9, changes in mouse brain after in vivo starvation and high-fat diet

The Neuronal and Peripheral Expressed Membrane-Bound UNC93A Respond to Nutrient Availability in Mice

Ceder, Mikaela; Lekholm, Emilia; Hellsten, Sofie V; Perland, Emelie et al.

Ingår i Frontiers in Molecular Neuroscience, 2017

• DOI för The Neuronal and Peripheral Expressed Membrane-Bound UNC93A Respond to Nutrient Availability in Mice
• Ladda ner fulltext (pdf) av The Neuronal and Peripheral Expressed Membrane-Bound UNC93A Respond to Nutrient Availability in Mice

A Combinatorial Approach to Induce Sensory Axon Regeneration into the Dorsal Root Avulsed Spinal Cord

Hoeber, Jan; König, Niclas; Trolle, Carl; Lekholm, Emilia et al.

Ingår i Stem Cells and Development, s. 1065-1077, 2017

• DOI för A Combinatorial Approach to Induce Sensory Axon Regeneration into the Dorsal Root Avulsed Spinal Cord

Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability

Lekholm, Emilia; Perland, Emelie; Eriksson, Mikaela M.; Hellsten, Sofie V. et al.

Ingår i Frontiers in Molecular Neuroscience, 2017

• DOI för Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability
• Ladda ner fulltext (pdf) av Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability

The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake

Perland, Emelie; Hellsten, Sofie V.; Lekholm, Emilia; Eriksson, Mikaela M. et al.

Ingår i Journal of Molecular Neuroscience, s. 199-214, 2017

• DOI för The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake
• Ladda ner fulltext (pdf) av The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake

mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

Caruso, Vanni; Sreedharan, Smitha; Carlini, Valeria P.; Jacobsson, Josefin A. et al.

Ingår i Gene, s. 139-145, 2016

• DOI för mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies

Williams, Michael J.; Perland, Emelie; Eriksson, Mikaela M.; Carlsson, Josef et al.

Ingår i Frontiers in Aging Neuroscience, 2016

• DOI för Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies
• Ladda ner fulltext (pdf) av Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies

Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney

Roshanbin, Sahar; Lindberg, Frida; Lekholm, Emilia; Perland, Emelie et al.

Ingår i BMC Neuroscience, 2016

• DOI för Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney
• Ladda ner fulltext (pdf) av Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney

Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake

Herisson, F. M.; Waas, J. R.; Fredriksson, Robert; Schiöth, Helgi B. et al.

Ingår i Journal of neuroendocrinology, 2016

• DOI för Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake

The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder

Williams, Michael; Klockars, Anica; Eriksson, Anders; Voisin, Sarah et al.

Ingår i PLOS Genetics, 2016

• DOI för The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder
• Ladda ner fulltext (pdf) av The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder

The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis

Perland, Emelie; Lekholm, Emilia; Eriksson, Mikaela M.; Bagchi, Sonchita et al.

Ingår i PLOS ONE, 2016

• DOI för The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis
• Ladda ner fulltext (pdf) av The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis

Amino acid deprivation of neuronal cells changes expression levels of numerous transporters from the SLC family, including several members of the SLC38 family

Hellsten, Sofie Victora; Perland, Emelie; Lekholm, Emilia; Ahmad, Tauseef et al.

2016

The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

Wiemerslage, Lyle; Gohel, Priya A.; Maestri, Giulia; Hilmarsson, Torfi G. et al.

Ingår i Journal of Endocrinology, s. 233-243, 2016

• DOI för The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.

Rask-Andersen, Mathias; Sällman Almén, Markus; Jacobsson, Josefin A; Ameur, Adam et al.

Ingår i Genetical Research, 2015

• DOI för Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.

Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients

Nilsson, Emil; Ernst, Barbara; Voisin, Sarah; Sällman Almén, Markus et al.

Ingår i PLOS ONE, 2015

• DOI för Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients
• Ladda ner fulltext (pdf) av Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients

Implication of coronin 7 in body weight regulation in humans, mice and flies

Eriksson, Anders; Williams, Michael J.; Voisin, Sarah; Hansson, Ida et al.

Ingår i BMC Neuroscience, 2015

• DOI för Implication of coronin 7 in body weight regulation in humans, mice and flies
• Ladda ner fulltext (pdf) av Implication of coronin 7 in body weight regulation in humans, mice and flies

The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

Caruso, Vanni; Le Greves, Madeleine; Fard, Shahrzad Shirazi; Haitina, Tatjana et al.

Ingår i PLOS ONE, 2015

• DOI för The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake
• Ladda ner fulltext (pdf) av The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity

Zheleznyakova, Galina Yu; Nilsson, Emil K.; Kiselev, Anton V.; Maretina, Marianna A. et al.

Ingår i PLOS ONE, 2015

• DOI för Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity
• Ladda ner fulltext (pdf) av Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity

GABA and its B-receptor are present at the node of Ranvier in a small population of sensory fibers, implicating a role in myelination

Corell, Mikael; Wicher, Grzegorz; Radomska, Katarzyna J; Dağlıkoca, E Duygu et al.

Ingår i Journal of Neuroscience Research, s. 285-295, 2015

• DOI för GABA and its B-receptor are present at the node of Ranvier in a small population of sensory fibers, implicating a role in myelination

The obesity-linked Nudt3 Drosophila homolog Aps is associated with insulin signalling

Williams, Michael; Eriksson, Anders; Shaik, Muksheed; Voisin, Sarah et al.

Ingår i Molecular Endocrinology, s. 1303-1319, 2015

• DOI för The obesity-linked Nudt3 Drosophila homolog Aps is associated with insulin signalling

Transport of L-glutamine, L-alanine, L-arginine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS

Hägglund, Maria G A; Hellsten, Sofie V; Bagchi, Sonchita; Philippot, Gaëtan et al.

Ingår i Journal of Molecular Biology, s. 1495-1512, 2015

• DOI för Transport of L-glutamine, L-alanine, L-arginine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS

Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

Krishnan, Arunkumar; Mustafa, Arshi; Almén, Markus Sällman; Fredriksson, Robert et al.

Ingår i Molecular Phylogenetics and Evolution, s. 27-40, 2015

• DOI för Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals

Krishnan, Arunkumar; Dnyansagar, Rohit; Almén, Markus Sällman; Williams, Michael J. et al.

Ingår i BMC Evolutionary Biology, 2014

• DOI för The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
• Ladda ner fulltext (pdf) av The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity

Almén, Markus Sällman; Nilsson, Emil K.; Jacobsson, Josefin A.; Kalnina, Ineta et al.

Ingår i Gene, s. 61-67, 2014

• DOI för Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity
• Ladda ner fulltext (pdf) av Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity

Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster

Williams, Michael; Goergen, Philip; Rajendran, Jayasimman; Zheleznyakova, Galina et al.

Ingår i PLOS Genetics, 2014

• DOI för Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster
• Ladda ner fulltext (pdf) av Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster

The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

Caruso, Vanni; Hägglund, Maria G.; Badiali, Luca; Bagchi, Sonchita et al.

Ingår i Gene, s. 1-6, 2014

• DOI för The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population

Brooks, Samantha J; Nilsson, Emil K; Jacobsson, Josefin A; Stein, Dan J et al.

Ingår i PLOS ONE, 2014

• DOI för BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population
• Ladda ner fulltext (pdf) av BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population

Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats

Alsiö, Johan; Rask-Andersen, Mathias; Chavan, Rohit A.; Olszewski, Pawel K. et al.

Ingår i Neuroscience Letters, s. 18-23, 2014

• DOI för Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats

Insights into the Origin of Nematode Chemosensory GPCRs: Putative Orthologs of the Srw Family Are Found across Several Phyla of Protostomes

Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert; Schiöth, Helgi B.

Ingår i PLOS ONE, 2014

• DOI för Insights into the Origin of Nematode Chemosensory GPCRs: Putative Orthologs of the Srw Family Are Found across Several Phyla of Protostomes
• Ladda ner fulltext (pdf) av Insights into the Origin of Nematode Chemosensory GPCRs: Putative Orthologs of the Srw Family Are Found across Several Phyla of Protostomes

Histological Analysis of SLC38A6 (SNAT6) Expression in Mouse Brain Shows Selective Expression in Excitatory Neurons with High Expression in the Synapses

Bagchi, Sonchita; Baomar, Hajar Ali; Al-Walai, Somar; Al-Sadi, Saifaddin et al.

Ingår i PLOS ONE, 2014

• DOI för Histological Analysis of SLC38A6 (SNAT6) Expression in Mouse Brain Shows Selective Expression in Excitatory Neurons with High Expression in the Synapses
• Ladda ner fulltext (pdf) av Histological Analysis of SLC38A6 (SNAT6) Expression in Mouse Brain Shows Selective Expression in Excitatory Neurons with High Expression in the Synapses

CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children

Rask-Andersen, Mathias; Philippot, Gaetan; Moschonis, George; Dedoussis, George et al.

Ingår i PLOS ONE, 2014

• DOI för CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children
• Ladda ner fulltext (pdf) av CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children

PAT4 is abundantly expressed in excitatory and inhibitory neurons as well as epithelial cells

Roshanbin, Sahar; Hellsten, Sofie V; Tafreshiha, Atieh; Zhu, Yinan et al.

Ingår i Brain Research, s. 12-25, 2014

• DOI för PAT4 is abundantly expressed in excitatory and inhibitory neurons as well as epithelial cells
• Ladda ner fulltext (pdf) av PAT4 is abundantly expressed in excitatory and inhibitory neurons as well as epithelial cells

The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour

Williams, Michael J.; Goergen, Philip; Phad, Ganesh; Fredriksson, Robert et al.

Ingår i European Journal of Neuroscience, s. 2513-2526, 2014

• DOI för The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour

Exposure to Bisphenol A Affects Lipid Metabolism in Drosophila melanogaster

Williams, Michael J; Wang, Yi; Klockars, Anica; Lind, Monica et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 414-420, 2014

• DOI för Exposure to Bisphenol A Affects Lipid Metabolism in Drosophila melanogaster

Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

Williams, Michael J; Goergen, Philip; Rajendran, Jayasimman; Klockars, Anica et al.

Ingår i Genetics, s. 349-362, 2014

• DOI för Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system

Hägglund, Maria G. A.; Hellsten, Sofie V.; Bagchi, Sonchita; Ljungdahl, Anna et al.

Ingår i BMC Neuroscience, s. 54, 2013

• DOI för Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system
• Ladda ner fulltext (pdf) av Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system

Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity

Zheleznyakova, Galina Y.; Voisin, Sarah; Kiselev, Anton V.; Almén, Markus Sällman et al.

Ingår i European Journal of Human Genetics, s. 988-993, 2013

• DOI för Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity

Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes

Drgonova, Jana; Jacobsson, Josefin A.; Han, Joan C.; Yanovski, Jack A. et al.

Ingår i PLOS ONE, 2013

• DOI för Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes
• Ladda ner fulltext (pdf) av Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes

The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children

Rask-Andersen, Mathias; Moschonis, George; Chrousos, George; Marcus, Claude et al.

Ingår i PLOS ONE, 2013

• DOI för The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children
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B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain

Hägglund, Maria G A; Roshanbin, Sahar; Löfqvist, Erik; Hellsten, Sofie V et al.

Ingår i PLOS ONE, 2013

• DOI för B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain
• Ladda ner fulltext (pdf) av B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain

Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire

Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert; Schiöth, Helgi B.

Ingår i Gene, s. 122-133, 2013

• DOI för Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire

Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs)

Valsalan, Ravisankar; Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert et al.

Ingår i General and Comparative Endocrinology, s. 123-132, 2013

• DOI för Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs)

Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

Sällman Almén, Markus; Rask-Andersen, Mathias; Jacobsson, Josefin A; Ameur, Adam et al.

Ingår i International Journal of Obesity, s. 424-431, 2013

• DOI för Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children

Rask-Andersen, Mathias; Jacobsson, Josefin A.; Moschonis, George; Ek, Anna E. et al.

Ingår i BMC Medical Genetics, s. 36, 2012

• DOI för The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children
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Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

Almén, Markus Sällman; Jacobsson, Josefin A.; Moschonis, George; Benedict, Christian et al.

Ingår i Genomics, s. 132-137, 2012

• DOI för Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans

Olszewski, Pawel K.; Rozman, Jan; Jacobsson, Josefin A.; Rathkolb, Birgit et al.

Ingår i PLoS Genetics, 2012

• DOI för Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans
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Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats

Rask-Andersen, Mathias; Jacobsson, Josefin A.; Moschonis, George; Chavan, Rohit A. et al.

Ingår i European Journal of Human Genetics, s. 192-197, 2012

• DOI för Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats

The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

Krishnan, Arunkumar; Sällaman Almén, Markus; Fredriksson, Robert; Schiöth, Helgi B

Ingår i PLOS ONE, 2012

• DOI för The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi
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The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members

Sällman Almén, Markus; Bringeland, Nathalie; Fredriksson, Robert; Schiöth, Helgi B.

Ingår i PLOS ONE, 2012

• DOI för The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members
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Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)

Västermark, Åke; Krishnan, Arunkumar; Houle, Michael E.; Fredriksson, Robert et al.

Ingår i PLOS ONE, 2012

• DOI för Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)
• Ladda ner fulltext (pdf) av Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)

Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes

Sundström, Görel; Xu, Bo; Larsson, Tomas A; Heldin, Johan et al.

Ingår i General and Comparative Endocrinology, s. 322-331, 2012

• DOI för Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes

Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden

Västermark, Åke; Jacobsson, Josefin; Johansson, Åsa; Fredriksson, Robert et al.

Ingår i Journal of Genetics, s. 237-240, 2012

• DOI för Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden

Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children

Jacobsson, Josefin; Rask-Andersen, Mathias; Risérus, Ulf; Moschonis, G et al.

Ingår i International Journal of Obesity, s. 119-129, 2012

• DOI för Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children

Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae

Västermark, Åke; Almén, Markus Sällman; Simmen, Martin W.; Fredriksson, Robert et al.

Ingår i BMC Evolutionary Biology, s. 123, 2011

• DOI för Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae

Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway

Rask-Andersen, Mathias; Sällman Almén, Markus; Olausen, Hans R.; Olszewski, Pawel K. et al.

Ingår i BMC Neuroscience, s. 117, 2011

• DOI för Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway
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Detailed Analysis of Variants in FTO in Association with Body Composition in a Cohort of 70-Year-Olds Suggests a Weakened Effect among Elderly

Jacobsson, Josefin A.; Sällman Almén, Markus; Benedict, Christian; Hedberg, Lilia A. et al.

Ingår i PLOS ONE, 2011

• DOI för Detailed Analysis of Variants in FTO in Association with Body Composition in a Cohort of 70-Year-Olds Suggests a Weakened Effect among Elderly

The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men

Benedict, Christian; Jacobsson, Josefin A; Rönnemaa, Elina; Sällman Almén, Markus et al.

Ingår i Neurobiology of Aging, s. 11590-115900000, 2011

• DOI för The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men

Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract

Cedernaes, Jonathan; Olszewski, Pawel K.; Sällman Almén, Markus; Stephansson, Olga et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 702-707, 2011

• DOI för Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract

Identification of SLC38A7 (SNAT7) Protein as a Glutamine Transporter Expressed in Neurons

Hägglund, Maria G. A.; Sreedharan, Smitha; Nilsson, Victor C. O.; Shaik, Jafar H. A. et al.

Ingår i Journal of Biological Chemistry, s. 20500-20511, 2011

• DOI för Identification of SLC38A7 (SNAT7) Protein as a Glutamine Transporter Expressed in Neurons

Fto colocalizes with a satiety mediator oxytocin in the brain and upregulates oxytocin gene expression

Olszewski, Pawel K.; Fredriksson, Robert; Eriksson, Jenny D.; Mitra, Anaya et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 422-426, 2011

• DOI för Fto colocalizes with a satiety mediator oxytocin in the brain and upregulates oxytocin gene expression

Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance

Olszewski, Pawel K.; Radomska, Katarzyna J.; Ghimire, Kedar; Klockars, Anica et al.

Ingår i Physiology and Behavior, s. 248-253, 2011

• DOI för Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance

The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species

Höglund, Pär J.; Nordström, Karl J. V.; Schiöth, Helgi B.; Fredriksson, Robert

Ingår i Molecular biology and evolution, s. 1531-1541, 2011

• DOI för The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species

Associations between severity of obesity in childhood and adolescence, obesity onset andparental BMI: a longitudinal cohort study

Svensson, Viktoria; Jacobsson, Josefin A; Fredriksson, Robert; Danielsson, Pernilla et al.

Ingår i International Journal of Obesity, s. 46-52, 2011

• DOI för Associations between severity of obesity in childhood and adolescence, obesity onset andparental BMI: a longitudinal cohort study

Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

Nordström, Karl; Sällman Almén, Markus; Edstam, Monika; Fredriksson, Robert et al.

Ingår i Molecular biology and evolution, s. 2471-2480, 2011

Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters

Sreedharan, Smitha; Stephansson, Olga; Schiöth, Helgi B.; Fredriksson, Robert

Ingår i Gene, s. 11-18, 2011

• DOI för Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters

Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

Nordström, Karl; Sällman Almén, Markus; Edstam, Monika; Fredriksson, Robert et al.

Ingår i Molecular biology and evolution, s. 2471-2480, 2011

• DOI för Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

Sreedharan, Smitha; Sällman Almén, Markus; Carlini, Valeria P; Haitina, Tatjana et al.

Ingår i The FEBS Journal, s. 4881-4894, 2011

• DOI för The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees

Hill, Tobias; Nordström, Karl J V; Thollesson, Mikael; Säfström, Tommy M et al.

Ingår i BMC Evolutionary Biology, s. 42, 2010

• DOI för SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees

Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

Sreedharan, Smitha; Shaik, Jafar H A; Olszewski, Pawel K; Levine, Allen S et al.

Ingår i BMC Genomics, s. 17, 2010

• DOI för Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

Almén, Markus Sällman; Jacobsson, Josefin A.; Shaik, Jafar H. A.; Olszewski, Pawel K. et al.

Ingår i BMC Medical Genetics, s. 58, 2010

• DOI för The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

C6ORF192 forms a unique evolutionary branch among solute carriers (SLC16, SLC17, and SLC18) and is abundantly expressed in several brain regions

Jacobsson, Josefin A.; Stephansson, Olga; Fredriksson, Robert

Ingår i Journal of Molecular Neuroscience, s. 230-242, 2010

• DOI för C6ORF192 forms a unique evolutionary branch among solute carriers (SLC16, SLC17, and SLC18) and is abundantly expressed in several brain regions

Molecular, Immunohistochemical, and Pharmacological Evidence of Oxytocin's Role as Inhibitor of Carbohydrate But Not Fat Intake

Olszewski, Pawel K.; Klockars, Anica; Olszewska, Agnieszka M.; Fredriksson, Robert et al.

Ingår i Endocrinology, s. 4736-4744, 2010

• DOI för Molecular, Immunohistochemical, and Pharmacological Evidence of Oxytocin's Role as Inhibitor of Carbohydrate But Not Fat Intake

Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

Olszewski, Pawel K; Fredriksson, Robert; Olszewska, Agnieszka M; Stephansson, Olga et al.

Ingår i BMC Neuroscience, s. 129, 2009

• DOI för Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

Almén, Markus Sällman; Nordström, Karl J V; Fredriksson, Robert; Schiöth, Helgi B

Ingår i BMC Biology, s. 50, 2009

• DOI för Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Haitina, Tatjana; Fredriksson, Robert; Foord, Steven M.; Schiöth, Helgi B. et al.

Ingår i BMC Genomics, s. 24, 2009

• DOI för The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924

Jacobsson, Josefin A; Risérus, Ulf; Axelsson, Tomas; Lannfelt, Lars et al.

Ingår i BMC Medical Genetics, s. 131, 2009

• DOI för The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924

Sequence polymorphism in a marine bivalve (Perna canaliculus) orphan G protein-coupled receptor gene: preliminary description and possible implications

Fidler, Andrew E.; Schiöth, Helgi B.; Fredriksson, Robert

Ingår i New Zealand Journal of Marine and Freshwater Research, s. 953-964, 2009

Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2

Alsiö, Johan; Roman, Erika; Olszewski, Pawel K.; Jonsson, Petra et al.

Ingår i Genes, Brain and Behavior, s. 193-202, 2009

• DOI för Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2

Neuropeptide Y-family peptides and receptors in the elephant shark, Callorhinchus milii confirm gene duplications before the gnathostome radiation

Larsson, Tomas A.; Tay, Boon-Hui; Sundström, Görel; Fredriksson, Robert et al.

Ingår i Genomics, s. 254-260, 2009

• DOI för Neuropeptide Y-family peptides and receptors in the elephant shark, Callorhinchus milii confirm gene duplications before the gnathostome radiation

Critical evaluation of the FANTOM3 non-coding RNA transcripts

Nordström, Karl J V; Mirza, Majd A I; Almén, Markus Sällman; Gloriam, David E et al.

Ingår i Genomics, s. 169-176, 2009

• DOI för Critical evaluation of the FANTOM3 non-coding RNA transcripts

Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY

Olszewski, Pawel K; Shaw, Timothy J; Grace, Martha K; Höglund, Catherine E et al.

Ingår i Peptides, s. 226-233, 2009

• DOI för Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY

The Secretin GPCRs descended from the family of Adhesion GPCRs

Nordström, Karl J V; Lagerström, Malin C; Wallér, Linn M J; Fredriksson, Robert et al.

Ingår i Molecular biology and evolution, s. 71-84, 2009

• DOI för The Secretin GPCRs descended from the family of Adhesion GPCRs

Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

Wallén-Mackenzie, Åsa; Nordenankar, Karin; Fejgin, Kim; Lagerström, Malin C et al.

Ingår i Journal of Neuroscience, s. 2238-2251, 2009

• DOI för Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

Nordström, Karl J V; Fredriksson, Robert; Schiöth, Helgi B

Ingår i BMC Evolutionary Biology, s. 9, 2008

• DOI för The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

Pickering, Chris; Hägglund, Maria; Szmydynger-Chodobska, Joanna; Marques, Fernanda et al.

Ingår i BMC Neuroscience, s. 97, 2008

• DOI för The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

Haitina, Tatjana; Olsson, Fredrik; Stephansson, Olga; Alsiö, Johan et al.

Ingår i BMC Neuroscience, s. 43, 2008

• DOI för Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families

Fredriksson, Robert; Nordström, Karl J V; Stephansson, Olga; Hägglund, Maria G A et al.

Ingår i FEBS Letters, s. 3811-3816, 2008

• DOI för The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families

The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression

Johansson, Andreas; Fredriksson, Robert; Winnergren, Sonja; Hulting, Anna-Lena et al.

Ingår i Peptides, s. 1588-1595, 2008

• DOI för The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression

Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes.

Jacobsson, Josefin A.; Danielsson, Pernilla; Svensson, Victoria; Klovins, Janis et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 476-482, 2008

• DOI för Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes.

The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain

Fredriksson, Robert; Hägglund, Maria; Olszewski, Pawel K; Stephansson, Olga et al.

Ingår i Endocrinology, s. 2062-71, 2008

• DOI för The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain

Allelotyping by massively parallel pyrosequencing of SNP-carrying trinucleotide threads

Pettersson, Erik; Zajac, Pawel; Ståhl, Patrik L; Jacobsson, Josefin A et al.

Ingår i Human Mutation, s. 323-329, 2008

• DOI för Allelotyping by massively parallel pyrosequencing of SNP-carrying trinucleotide threads

The evolutionary history and tissue mapping of amino acid transporters belonging to solute carrier families SLC32, SLC36, and SLC38

Sundberg, Björn E; Wååg, Elin; Jacobsson, Josefin A; Stephansson, Olga et al.

Ingår i Journal of Molecular Neuroscience, s. 179-193, 2008

• DOI för The evolutionary history and tissue mapping of amino acid transporters belonging to solute carrier families SLC32, SLC36, and SLC38

The G protein-coupled receptor subset of the rat genome

Gloriam, David E; Fredriksson, Robert; Schiöth, Helgi B

Ingår i BMC Genomics, s. 338, 2007

• DOI för The G protein-coupled receptor subset of the rat genome

Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

Haitina, Tatjana; Klovins, Janis; Takahashi, Akiyoshi; Löwgren, Maja et al.

Ingår i BMC Evolutionary Biology, s. 101, 2007

• DOI för Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

Anxiety-like behaviour predicts the preference for a high-carbohydrate diet in outbred rats

Alsiö, Johan; Roman, Erika; Fredriksson, Robert; Hulting, Anna-Lena et al.

Ingår i Behavioural Pharmacology, 2007

Quantitative Trait Loci for BMD and Bone Strength in an Intercross Between Domestic and Wildtype Chickens

Rubin, Carl-Johan; Brändström, Helena; Wright, Dominic; Kerje, Susanne et al.

Ingår i Journal of Bone and Mineral Research, s. 375-384, 2007

• DOI för Quantitative Trait Loci for BMD and Bone Strength in an Intercross Between Domestic and Wildtype Chickens

Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family

Jacobsson, Josefin A.; Haitina, Tatjana; Lindblom, Jonas; Fredriksson, Robert

Ingår i Genomics, s. 595-609, 2007

• DOI för Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family

Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors

Fridmanis, Davids; Fredriksson, Robert; Kapa, Ivo; Schiöth, Helgi B. et al.

Ingår i Molecular Phylogenetics and Evolution, s. 864-880, 2007

• DOI för Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors

Mining the gene repertoire and ESTs for G protein-coupled receptors with evolutionary perspective

Schiöth, Helgi B.; Nordström, K. J. V.; Fredriksson, Robert

Ingår i Acta Physiologica, s. 21-31, 2007

• DOI för Mining the gene repertoire and ESTs for G protein-coupled receptors with evolutionary perspective

Identification of novel splice variants of Adhesion G protein-coupled receptors

Bjarnadóttir, Thóra K.; Geirardsdóttir, Kristín; Ingemansson, Malena; Mirza, Majd A. I. et al.

Ingår i Gene, s. 38-48, 2007

• DOI för Identification of novel splice variants of Adhesion G protein-coupled receptors

Characterization of NPY receptor subtypes Y2 and Y7 in rainbow trout Oncorhynchus mykiss

Larsson, Tomas A; Larson, Earl T; Fredriksson, Robert; Conlon, J Michael et al.

Ingår i Peptides, s. 1320-1327, 2006

• DOI för Characterization of NPY receptor subtypes Y2 and Y7 in rainbow trout Oncorhynchus mykiss

Neuropeptide Y-family receptors Y₆ and Y₇ in chicken: Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region

Bromée, Torun; Sjödin, Paula; Fredriksson, Robert; Boswell, Tim et al.

Ingår i The FEBS Journal, s. 2048-2063, 2006

• DOI för Neuropeptide Y-family receptors Y₆ and Y₇ in chicken: Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region

The G protein-coupled receptor subset of the chicken genome

Lagerström, Malin C.; Hellström, Anders R.; Gloriam, David E.; Larsson, Thomas P. et al.

Ingår i PloS Computational Biology, 2006

• DOI för The G protein-coupled receptor subset of the chicken genome

Evaluation of EST-data using the genome assembly

Murray, Christian; Larsson, Thomas; Hill, Tobias; Björklind, Rikard et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 1566-1576, 2005

• DOI för Evaluation of EST-data using the genome assembly

Feather pecking in chickens is genetically related to behavioural and developmental traits

Jensen, Per; Keeling, L.; Schutz, K.; Andersson, L. et al.

Ingår i Physiology and Behavior, s. 52-60, 2005

• DOI för Feather pecking in chickens is genetically related to behavioural and developmental traits

Many QTLs with minor additive effects are associated with a large difference in growth between two selection lines in chickens.

Jacobsson, Lina; Park, Hee-Bok; Wahlberg, Per; Fredriksson, Robert et al.

Ingår i Genet Res, s. 115-25, 2005

Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes

Haitina, Tatjana; Klovins, Janis; Andersson, Jan; Fredriksson, Robert et al.

Ingår i Biochemical Journal, s. 475-486, 2004

• DOI för Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes

The Dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 gene.

Kerje, Susanne; Sharma, Preety; Gunnarsson, Ulrika; Kim, Hyun et al.

Ingår i Genetics, s. 1507-18, 2004

High affinity agonistic metal ion binding sites within the melanocortin 4 receptor illustrate conformational change of transmembrane region 3

Lagerström, Malin C.; Klovins, Janis; Fredriksson, Robert; Fridmanis, Davids et al.

Ingår i Journal of Biological Chemistry, s. 51521-51526, 2003

• DOI för High affinity agonistic metal ion binding sites within the melanocortin 4 receptor illustrate conformational change of transmembrane region 3

Transport of L-glutamine, L-alanine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS.: SNAT8 is a neuronal glutamine transporter.

Hägglund, Maria; Hellsten, Sofie; Bagchi, Sonchita; Philippot, Gaëtan et al.

Classification Systems of Secondary Active Transporters

Perland, Emelie; Fredriksson, Robert

Ingår i TIPS - Trends in Pharmacological Sciences, s. 305-315, 2017

• DOI för Classification Systems of Secondary Active Transporters

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors

Hamann, Joerg; Aust, Gabriela; Arac, Demet; Engel, Felix B. et al.

Ingår i Pharmacological Reviews, s. 338-367, 2015

• DOI för International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors

Synaptic changes induced by melanocortin signalling

Caruso, Vanni; Lagerström, Malin C.; Olszewski, Pawel K.; Fredriksson, Robert et al.

Ingår i Nature Reviews Neuroscience, s. 98-110, 2014

• DOI för Synaptic changes induced by melanocortin signalling

G Protein-Coupled Receptor Deorphanizations

Civelli, Olivier; Reinscheid, Rainer K; Zhang, Yan; Wang, Zhiwei et al.

Ingår i Annual Review of Pharmacology and Toxicology, s. 127-146, 2013

• DOI för G Protein-Coupled Receptor Deorphanizations

Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

Schiöth, Helgi B; Roshanbin, Sahar; Hägglund, Maria G A; Fredriksson, Robert

Ingår i Molecular Aspects of Medicine, s. 571-585, 2013

• DOI för Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

Solute carriers as drug targets: current use, clinical trials and prospective

Rask-Andersen, Mathias; Masuram, Surendar; Fredriksson, Robert; Schiöth, Helgi B

Ingår i Molecular Aspects of Medicine, s. 702-710, 2013

• DOI för Solute carriers as drug targets: current use, clinical trials and prospective

Exposure to subliminal arousing stimuli induces robust activation in the amygdala, hippocampus, anterior cingulate, insular cortex and primary visual cortex: A systematic meta-analysis of fMRI studies

Brooks, Samantha J.; Savov, Vasil; Allzen, E.; Benedict, Christian et al.

Ingår i NeuroImage, s. 2962-2973, 2012

• DOI för Exposure to subliminal arousing stimuli induces robust activation in the amygdala, hippocampus, anterior cingulate, insular cortex and primary visual cortex: A systematic meta-analysis of fMRI studies

What model organisms and interactomics can reveal about the genetics of human obesity

Williams, Michael J.; Almén, Markus Sällman; Fredriksson, Robert; Schiöth, Helgi B.

Ingår i Cellular and Molecular Life Sciences (CMLS), s. 3819-3834, 2012

• DOI för What model organisms and interactomics can reveal about the genetics of human obesity

The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity gene FTO

Jacobsson, Josefin A.; Schioth, Helgi B.; Fredriksson, Rorbert

Ingår i Obesity Reviews, s. 1096-1109, 2012

• DOI för The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity gene FTO

The adhesion GPCRs: a unique family of G protein-coupled receptors with important roles in both central and peripheral tissues

Bjarnadóttir, T K; Fredriksson, Robert; Schiöth, Helgi B

Ingår i Cellular and Molecular Life Sciences (CMLS), s. 2104-2119, 2007

• DOI för The adhesion GPCRs: a unique family of G protein-coupled receptors with important roles in both central and peripheral tissues

In Situ Proximity Ligation Assay (PLA)

Bagchi, Sonchita; Fredriksson, Robert; Wallén-Mackenzie, Åsa

Ingår i ELISA, s. 149-159, Springer-Verlag New York, 2015

• DOI för In Situ Proximity Ligation Assay (PLA)

The Adhesion GPCRs; Gene Repertoire, Phylogeny and Evolution

Schiöth, Helgi B.; Nordström, Karl J. V.; Fredriksson, Robert

Ingår i ADHESION-GPCRS, s. 1-13, Springer Berlin/Heidelberg, 2010

• DOI för The Adhesion GPCRs; Gene Repertoire, Phylogeny and Evolution

Characterization of a unique amino acid transporter, SNAT10, in the Golgi apparatus

Bagchi, Sonchita; Hellsten, Sofie Victora; Hägglund, Maria; Arapi, Vasiliki et al.

2016

Ultra-deep targeted re-sequencing of TMEM18 in two cohorts of European children detects new genetic variants associated with obesity

Rask-Andersen, Mathias; Sällman Almén, Markus; Jacobsson, Josefin; Ameur, Adam et al.

2013

GPR162 is expressed in the hypothalamus and is involved in food intake related behaviour

Sreedharan, Smitha; Carlini, Valeria P; Jacobsson, Josefin A; Olszewski, Pawel K et al.

2011

SLC38A9 is expressed in inhibitory and excitatory neurons and the gene expression changes in mouse brain after starvation and high-fat diet

Hellsten, Sofie Victora; Eriksson, Mikaela; Lekholm, Emilia; Perland, Emelie et al.

Vglut2 gene expression in limbic brain areas of outbred rats following exposure to nicotine and ethanol

Vrettou, Maria; Thalhammer, Stefan; Svensson, Anne-Lie; Nilsson, Kent W. et al.

Integrated analysis of transcriptomic and metabolic profiling of SLC38A10 knockout  primary cortex cells

Tripathi, Rekha; Fredriksson, Rorbert

Cellular uptake and intra-brain distribution of cyclic cell penetrating peptides: why tissue and cell type matters

Melander, Erik; Hosseini, Kimia; Eriksson, Camilla; Fredriksson, Robert et al.

Glucose deprived mouse embryonal cortex cultures respond by altering MFS transporter expression and localization

Lekholm, Emilia; Eriksson, Mikaela; Klaesson, Axel; Perland, Emelie et al.

Treatment of two human neuroblastoma cell lines with growth factors, ATRA or VIP alters synaptic vesicle glycoprotein 2 (SV2) expression.

Lekholm, Emilia; Eriksson, Mikaela; Forsberg, Erica; Schiöth, Helgi B. et al.

Statins inhibit neurite outgrowth and induce morphological changes in cellular compartments in maturing neurons derived from human neural stem cells

Hosseini, Kimia; Ceder, Mikaela M.; Jonsson, Jörgen; Schiöth, Helgi et al.