Markus Sjöblom

Effects of intestinal permeation enhancers on solubilization and epithelial transport of the proteolysis targeting chimera (PROTAC) ARV-471 in rats

Niessen, Janis; Koziolek, Mirko; Borchardt, Thomas; Indulkar, Anura S. et al.

Ingår i Journal of Controlled Release, 2026

• DOI för Effects of intestinal permeation enhancers on solubilization and epithelial transport of the proteolysis targeting chimera (PROTAC) ARV-471 in rats
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The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant)

Niessen, Janis; Koziolek, Mirko; Indulkar, Anura; Borchardt, Thomas et al.

Ingår i Molecular Pharmaceutics, s. 3445-3457, 2026

• DOI för The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant)
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Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

Lerma-Clavero, Ada; Kopsida, Maria; Arendt, Nathalie; Lennernäs, Hans et al.

Ingår i FEBS Open Bio, 2026

• DOI för Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling
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Prevalence of gastrointestinal side effects in hepatocellular carcinoma patients receiving sorafenib: a meta-analysis of 136 studies and 14,416 patients

Arendt, Nathalie; Payo-Serafin, Tania; Kolosenko, Anna; Kopsida, Maria et al.

Ingår i Therapeutic Advances in Medical Oncology, 2026

• DOI för Prevalence of gastrointestinal side effects in hepatocellular carcinoma patients receiving sorafenib: a meta-analysis of 136 studies and 14,416 patients
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A comparative study of idarubicin and doxorubicin in a chemically-induced in vivo mouse model for hepatocellular carcinoma

Lerma-Clavero, Ada; Kopsida, Maria; Arendt, Nathalie; Lennernäs, Hans et al.

Ingår i Biomedicine and Pharmacotherapy, 2025

• DOI för A comparative study of idarubicin and doxorubicin in a chemically-induced in vivo mouse model for hepatocellular carcinoma
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Effects of intestinal permeation enhancers on solubilization and epithelial transport of the proteolysis targeting chimera (PROTAC) ARV-471 in rats

Niessen, Janis; Koziolek, Mirko; Borchardt, Thomas; Indulkar, Anura S. et al.

Ingår i Journal of Controlled Release, 2026

• DOI för Effects of intestinal permeation enhancers on solubilization and epithelial transport of the proteolysis targeting chimera (PROTAC) ARV-471 in rats
• Ladda ner fulltext (pdf) av Effects of intestinal permeation enhancers on solubilization and epithelial transport of the proteolysis targeting chimera (PROTAC) ARV-471 in rats

The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant)

Niessen, Janis; Koziolek, Mirko; Indulkar, Anura; Borchardt, Thomas et al.

Ingår i Molecular Pharmaceutics, s. 3445-3457, 2026

• DOI för The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant)
• Ladda ner fulltext (pdf) av The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

Lerma-Clavero, Ada; Kopsida, Maria; Arendt, Nathalie; Lennernäs, Hans et al.

Ingår i FEBS Open Bio, 2026

• DOI för Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling
• Ladda ner fulltext (pdf) av Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

Prevalence of gastrointestinal side effects in hepatocellular carcinoma patients receiving sorafenib: a meta-analysis of 136 studies and 14,416 patients

Arendt, Nathalie; Payo-Serafin, Tania; Kolosenko, Anna; Kopsida, Maria et al.

Ingår i Therapeutic Advances in Medical Oncology, 2026

• DOI för Prevalence of gastrointestinal side effects in hepatocellular carcinoma patients receiving sorafenib: a meta-analysis of 136 studies and 14,416 patients
• Ladda ner fulltext (pdf) av Prevalence of gastrointestinal side effects in hepatocellular carcinoma patients receiving sorafenib: a meta-analysis of 136 studies and 14,416 patients

A comparative study of idarubicin and doxorubicin in a chemically-induced in vivo mouse model for hepatocellular carcinoma

Lerma-Clavero, Ada; Kopsida, Maria; Arendt, Nathalie; Lennernäs, Hans et al.

Ingår i Biomedicine and Pharmacotherapy, 2025

• DOI för A comparative study of idarubicin and doxorubicin in a chemically-induced in vivo mouse model for hepatocellular carcinoma
• Ladda ner fulltext (pdf) av A comparative study of idarubicin and doxorubicin in a chemically-induced in vivo mouse model for hepatocellular carcinoma

Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients

Arendt, Nathalie; Kopsida, Maria; Khaled, Jaafar; Sjöblom, Markus et al.

Ingår i Therapeutic Advances in Medical Oncology, s. 1-30, 2025

• DOI för Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients
• Ladda ner fulltext (pdf) av Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients

Statin-mediated protection in chemotherapy-induced intestinal and cardiac toxicity: current perspectives

Arendt, Nathalie; Kopsida, Maria; Lennernäs, Hans; Sjöblom, Markus et al.

Ingår i European Journal of Pharmacology, 2025

• DOI för Statin-mediated protection in chemotherapy-induced intestinal and cardiac toxicity: current perspectives
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A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats

Niessen, Janis; Arendt, Nathalie; Sjöblom, Markus; Dubbelboer, Ilse R. et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, 2025

• DOI för A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats
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Melatonin mitigates chemotherapy-induced small intestinal atrophy in rats and reduces cytotoxicity in murine intestinal organoids

Peters, Karsten; Clavero, Ada Lerma; Kullenberg, Fredrik; Kopsida, Maria et al.

Ingår i PLOS ONE, 2024

• DOI för Melatonin mitigates chemotherapy-induced small intestinal atrophy in rats and reduces cytotoxicity in murine intestinal organoids
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LRBA, a BEACH protein mutated in human immune deficiency, is widely expressed in epithelia, exocrine and endocrine glands, and neurons

Roussa, Eleni; Juda, Pavel; Laue, Michael; Mai-Kolerus, Oliver et al.

Ingår i Scientific Reports, 2024

• DOI för LRBA, a BEACH protein mutated in human immune deficiency, is widely expressed in epithelia, exocrine and endocrine glands, and neurons
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Hypotonicity-Induced Increase in Duodenal Mucosal Permeability Is Regulated by Cholinergic Receptors in Rats

Dahlgren, David; Nylander, Olof; Sjöblom, Markus

Ingår i Digestive Diseases and Sciences, s. 1815-1823, 2023

• DOI för Hypotonicity-Induced Increase in Duodenal Mucosal Permeability Is Regulated by Cholinergic Receptors in Rats
• Ladda ner fulltext (pdf) av Hypotonicity-Induced Increase in Duodenal Mucosal Permeability Is Regulated by Cholinergic Receptors in Rats

The progression of doxorubicin-induced intestinal mucositis in rats

Kullenberg, Fredrik; Peters, Karsten; Luna-Marco, C.; Salomonsson, A. et al.

Ingår i Naunyn-Schmiedeberg's Archives of Pharmacology, s. 247-260, 2023

• DOI för The progression of doxorubicin-induced intestinal mucositis in rats
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Anakinra and dexamethasone treatment of idarubicin-induced mucositis and diarrhoea in rats

Kullenberg, Fredrik; Peters, Karsten; Sjöblom, Markus; Heindryckx, Femke et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 507-516, 2023

• DOI för Anakinra and dexamethasone treatment of idarubicin-induced mucositis and diarrhoea in rats
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Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats

Dahlgren, David; Rosenqvist, Evelina; Hellström, Per M.; Nygren, Peter et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 536-546, 2022

• DOI för Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats
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Effects of α₂-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum

Nylander, Olof; Sjöblom, Markus; Sedin, John; Dahlgren, David

Ingår i PLOS ONE, 2022

• DOI för Effects of α₂-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum
• Ladda ner fulltext (pdf) av Effects of α₂-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum

Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats

Cano-Cebrian, Maria-Jose; Dahlgren, David; Kullenberg, Fredrik; Peters, Karsten et al.

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
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Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats

Peters, Karsten; Dahlgren, David; Egerszegi, Peter Pal; Lennernäs, Hans et al.

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats
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The Impact of alpha-Adrenoceptors in the Regulation of the Hypotonicity-Induced Increase in Duodenal Mucosal Permeability In Vivo

Sedin, John; Dahlgren, David; Sjöblom, Markus; Nylander, Olof

Ingår i Pharmaceutics, 2021

• DOI för The Impact of alpha-Adrenoceptors in the Regulation of the Hypotonicity-Induced Increase in Duodenal Mucosal Permeability In Vivo
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Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats

Peters, Karsten; Dahlgren, David; Lennernäs, Hans; Sjöblom, Markus

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
• Ladda ner fulltext (pdf) av Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats

Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats

Dahlgren, David; Olander, Tobias; Sjöblom, Markus; Hedeland, Mikael et al.

Ingår i Acta Pharmaceutica Sinica B, s. 1667-1675, 2021

• DOI för Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
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Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat

Dahlgren, David; Cano-Cebrian, Maria-Jose; Olander, Tobias; Hedeland, Mikael et al.

Ingår i Pharmaceutics, 2020

• DOI för Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat
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Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol

Dahlgren, David; Cano-Cebrian, Maria-Jose; Hellström, Per M.; Wanders, Alkwin et al.

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol
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The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin

Dahlgren, David; Sjöblom, Markus; Hedeland, Mikael; Lennernäs, Hans

Ingår i Pharmaceutics, 2020

• DOI för The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
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Gunnar Flemström's legacy in intestinal bicarbonate secretion: A homage to Gunnar Flemström and his work in intestinal bicarbonate secretion

Seidler, Ursula; Nylander, Olof; Sjöblom, Markus; Birnir, Bryndis et al.

Ingår i Acta Physiologica, 2019

• DOI för Gunnar Flemström's legacy in intestinal bicarbonate secretion: A homage to Gunnar Flemström and his work in intestinal bicarbonate secretion

Intestinal absorption-modifying excipients: A current update on preclinical in vivo evaluations

Dahlgren, David; Sjöblom, Markus; Lennernäs, Hans

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 411-420, 2019

• DOI för Intestinal absorption-modifying excipients: A current update on preclinical in vivo evaluations

Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions

Roos, Carl; Dahlgren, David; Sjögren, Erik; Sjöblom, Markus et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 387-395, 2019

• DOI för Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions

Evaluation of drug permeability calculation based on luminal disappearance and plasma appearance in the rat single-pass intestinal perfusion model

Dahlgren, David; Roos, Carl; Peters, Karsten; Lundqvist, A. et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 31-37, 2019

• DOI för Evaluation of drug permeability calculation based on luminal disappearance and plasma appearance in the rat single-pass intestinal perfusion model

Time-dependent effects on small intestinal transport by absorption-modifying excipients

Dahlgren, David; Roos, Carl; Lundqvist, A.; Tannergren, C. et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 19-28, 2018

• DOI för Time-dependent effects on small intestinal transport by absorption-modifying excipients

Jejunal absorption of aprepitant from nanosuspensions: Role of particle size, prandial state and mucus layer.

Roos, Carl; Dahlgren, David; Sjögren, Erik; Sjöblom, Markus et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 222-230, 2018

• DOI för Jejunal absorption of aprepitant from nanosuspensions: Role of particle size, prandial state and mucus layer.

Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport.

Dahlgren, David; Roos, Carl; Lundqvist, A; Tannergren, C et al.

Ingår i International Journal of Pharmaceutics, s. 239-248, 2018

• DOI för Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport.

The effects of three absorption-modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs.

Dahlgren, David; Roos, Carl; Johansson, P; Tannergren, C et al.

Ingår i International Journal of Pharmaceutics, s. 158-168, 2018

• DOI för The effects of three absorption-modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs.

Short-chain fatty acids augment rat duodenal mucosal barrier function

Wan Saudi, Wan Salman; Sjöblom, Markus

Ingår i Experimental Physiology, s. 791-803, 2017

• DOI för Short-chain fatty acids augment rat duodenal mucosal barrier function

Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker ⁵¹Cr-EDTA

Dahlgren, David; Roos, Carl; Lundqvist, Anders; Tannergren, Christer et al.

Ingår i Molecular Pharmaceutics, s. 4243-4251, 2017

• DOI för Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker ⁵¹Cr-EDTA

Neuropeptide S reduces duodenal bicarbonate secretion and ethanol-induced increases in duodenal motility in rats

Wan Saudi, Wan Salman; Sjöblom, Markus

Ingår i PLOS ONE, 2017

• DOI för Neuropeptide S reduces duodenal bicarbonate secretion and ethanol-induced increases in duodenal motility in rats
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Neuropeptide S inhibits gastrointestinal motility and increases mucosal permeability through nitric oxide

Wan Saudi, Wan Salman; Halim, Mohammed Abdul; Gillberg, Linda; Rudholm-Feldreich, Tobias et al.

Ingår i American Journal of Physiology - Gastrointestinal and Liver Physiology, 2015

• DOI för Neuropeptide S inhibits gastrointestinal motility and increases mucosal permeability through nitric oxide

Clonidine abolishes the hypotonicity-induced increase in duodenal mucosal permeability by an alpha 2-adrenoceptor-mediated mechanism in rats

Sedin, John; Sjöblom, Markus; Nylander, Olof

Ingår i Acta Physiologica, s. 4-4, 2015

Effects of melatonin in ethanol-induced increases in duodenal mucosal permeability, motility and bicarbonate secretion in rats

Sommansson, Anna; Saudi, Wan Salman Wan; Nylander, Olof; Sjöblom, Markus

Ingår i Acta Physiologica, s. 2-3, 2015

Neuropeptide S Reduces Gut Motility in Rats and Humans

Saudi, Wan Salman Wan; Halim, Abdul; Webb, Dominic-Luc; Hellström, Per M. et al.

Ingår i The FASEB Journal, 2015

Neuropeptide S reduce small intestinal motility in rats and humans

Saudi, Wan Salman Wan; Halim, Abdul; Webb, Dominic-Luc; Gillberg, A. L. et al.

Ingår i Acta Physiologica, s. 94-94, 2014

Prevention of duodenal ileus reveals functional differences in the duodenal response to luminal hypertonicity in Sprague-Dawley and Dark Agouti rats

Sedin, John; Sjöblom, Markus; Nylander, Olof

Ingår i Acta Physiologica, s. 573-589, 2014

• DOI för Prevention of duodenal ileus reveals functional differences in the duodenal response to luminal hypertonicity in Sprague-Dawley and Dark Agouti rats

Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats

Sommansson, Anna; Yamskova, Olga; Schiöth, Helgi B.; Nylander, Olof et al.

Ingår i Acta Physiologica, s. 152-165, 2014

• DOI för Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats

The Ethanol-Induced Stimulation of Rat Duodenal Mucosal Bicarbonate Secretion In Vivo Is Critically Dependent on Luminal Cl-

Sommansson, Anna; Saudi, Wan Salman Wan; Nylander, Olof; Sjöblom, Markus

Ingår i PLOS ONE, 2014

• DOI för The Ethanol-Induced Stimulation of Rat Duodenal Mucosal Bicarbonate Secretion In Vivo Is Critically Dependent on Luminal Cl-
• Ladda ner fulltext (pdf) av The Ethanol-Induced Stimulation of Rat Duodenal Mucosal Bicarbonate Secretion In Vivo Is Critically Dependent on Luminal Cl-

Melatonin decreases duodenal epithelial paracellular permeability via a nicotinic receptor-dependent pathway in rats in vivo

Sommansson, Anna; Nylander, Olof; Sjöblom, Markus

Ingår i Journal of Pineal Research, s. 282-291, 2013

• DOI för Melatonin decreases duodenal epithelial paracellular permeability via a nicotinic receptor-dependent pathway in rats in vivo

Melatonin inhibits alcohol-induced increases in duodenal mucosal permeability in rats in vivo

Sommansson, Anna; Saudi, Wan Salman Wan; Nylander, Olof; Sjöblom, Markus

Ingår i American Journal of Physiology - Gastrointestinal and Liver Physiology, 2013

• DOI för Melatonin inhibits alcohol-induced increases in duodenal mucosal permeability in rats in vivo

Cholecystokinin but not ghrelin stimulates mucosal bicarbonate secretion in rat duodenum: Independence of feeding status and cholinergic stimuli

Sjöblom, Markus; Lindqvist, Ramin; Bengtsson, Magnus W.; Jedstedt, Gunilla et al.

Ingår i Regulatory Peptides, s. 46-53, 2013

• DOI för Cholecystokinin but not ghrelin stimulates mucosal bicarbonate secretion in rat duodenum: Independence of feeding status and cholinergic stimuli

The selective cyclooxygenase-2 inhibitor parecoxib markedly improves the ability of the duodenum to regulate luminal hypertonicity in anaesthetized rats

Sedin, John; Sjöblom, Markus; Nylander, Olof

Ingår i Acta Physiologica, s. 433-451, 2012

• DOI för The selective cyclooxygenase-2 inhibitor parecoxib markedly improves the ability of the duodenum to regulate luminal hypertonicity in anaesthetized rats

Apelin stimulation of duodenal bicarbonate secretion: feeding-dependent and mediated via apelin-induced release of enteric cholecystokinin

Flemström, Gunnar; Mäkelä, Kari; Purhonen, Anna-Kaisa; Sjöblom, Markus et al.

Ingår i Acta Physiologica, s. 141-150, 2011

• DOI för Apelin stimulation of duodenal bicarbonate secretion: feeding-dependent and mediated via apelin-induced release of enteric cholecystokinin

Motility-induced but not vasoactive intestinal peptide-induced increase in luminal alkalinization in rat duodenum is dependent on luminal Cl-

Pihl, Liselotte; Sjöblom, Markus; Seidler, U.; Sedin, John et al.

Ingår i Acta Physiologica, s. 181-191, 2010

• DOI för Motility-induced but not vasoactive intestinal peptide-induced increase in luminal alkalinization in rat duodenum is dependent on luminal Cl-

Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium.

Zheng, Wen; Kuhlicke, Johannes; Jäckel, Kristian; Eltzschig, Holger K et al.

Ingår i The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, s. 204-213, 2009

• DOI för Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium.

Duodenal acidity "sensing" but not epithelial HCO3- supply is critically dependent on carbonic anhydrase II expression

Sjöblom, Markus; Singh, Anurag Kumar; Zheng, Wen; Wang, Jian et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 13094-13099, 2009

• DOI för Duodenal acidity "sensing" but not epithelial HCO3- supply is critically dependent on carbonic anhydrase II expression

CFTR and its key role in in vivo resting and luminal acid-induced duodenal HCO3-secretion

Singh, A K; Sjöblom, Markus; Zheng, W; Krabbenhöft, A et al.

Ingår i Acta Physiologica, s. 357-365, 2008

• DOI för CFTR and its key role in in vivo resting and luminal acid-induced duodenal HCO3-secretion

Food-induced expression of orexin receptors in rat duodenal mucosa regulates the bicarbonate secretory response to orexin-A

Bengtsson, Magnus W.; Mäkelä, Kari; Sjöblom, Markus; Uotila, Sanna et al.

Ingår i American Journal of Physiology - Gastrointestinal and Liver Physiology, 2007

• DOI för Food-induced expression of orexin receptors in rat duodenal mucosa regulates the bicarbonate secretory response to orexin-A

Isoflurane-induced acidosis depresses basal and PGE(2)-stimulated duodenal bicarbonate secretion in mice

Sjöblom, Markus; Nylander, Olof

Ingår i American Journal of Physiology - Gastrointestinal and Liver Physiology, 2007

• DOI för Isoflurane-induced acidosis depresses basal and PGE(2)-stimulated duodenal bicarbonate secretion in mice

Modulation of mucosal permeability by vasoactive intestinal peptide or lidocaine affects the adjustment of luminal hypotonicity in rat duodenum

Nylander, Olof; Sjöblom, Markus

Ingår i Acta Physiologica, s. 325-335, 2007

• DOI för Modulation of mucosal permeability by vasoactive intestinal peptide or lidocaine affects the adjustment of luminal hypotonicity in rat duodenum

Serotonin increases protective duodenal bicarbonate secretion via enteric ganglia and a 5-HT4-dependent pathway

Säfsten, Bengt; Sjöblom, Markus; Flemström, Gunnar

Ingår i Scandinavian Journal of Gastroenterology, s. 1279-1289, 2006

• DOI för Serotonin increases protective duodenal bicarbonate secretion via enteric ganglia and a 5-HT4-dependent pathway

Epithelial Cells and Their Neighbors: II. New perspectives on efferent signaling between brain, neuroendocrine cells, and gut epithelial cells

Flemström, Gunnar; Sjöblom, Markus

Ingår i American Journal of Physiology - Gastrointestinal and Liver Physiology, 2005

• DOI för Epithelial Cells and Their Neighbors: II. New perspectives on efferent signaling between brain, neuroendocrine cells, and gut epithelial cells

The duodenal mucosal bicarbonate secretion.

Sjöblom, Markus

Ingår i Ups J Med Sci, s. 115-49, 2005

Carbonic anhydrase isozyme-II-deficient mice lack the duodenal bicarbonate secretory response to prostaglandin E2.

Leppilampi, Mari; Parkkila, Seppo; Karttunen, Tuomo; Gut, Marta Ortova et al.

Ingår i Proc Natl Acad Sci U S A, s. 15247-52, 2005

Central nervous alpha1-adrenoceptor stimulation induces duodenal luminal release of melatonin.

Sjöblom, Markus; Flemström, Gunnar

Ingår i J Pineal Res, s. 103-8, 2004

Melatonin in the duodenal lumen is a potent stimulant of mucosal bicarbonate secretion

Sjöblom, Markus; Flemström, Gunnar

Ingår i Journal of Pineal Research, s. 288-293, 2003

Melatonin-induced calcium signaling in clusters of human and rat duodenal enterocytes

Sjöblom, Markus; Säfsten, Bengt; Flemström, Gunnar

Ingår i American Journal of Physiology - Gastrointestinal and Liver Physiology, 2003

• DOI för Melatonin-induced calcium signaling in clusters of human and rat duodenal enterocytes

Short fasting dramatically decreases rat duodenal secretory responsiveness to orexin A but not to VIP or melatonin

Flemström, Gunnar; Sjöblom, Markus; Jedstedt, Gunilla; Åkerman, Karl EO

Ingår i American Journal of Physiology - Gastrointestinal and Liver Physiology, 2003

• DOI för Short fasting dramatically decreases rat duodenal secretory responsiveness to orexin A but not to VIP or melatonin

Duodenal defence mechanisms: Role of mucosal bicarbonate secretion

Flemström, Gunnar; Sjöblom, Markus

Ingår i InflammoPharmacology, s. 327-332, 2002

• DOI för Duodenal defence mechanisms: Role of mucosal bicarbonate secretion

Central nervous stimuli increase duodenal bicarbonate secretion by release of mucosal melatonin

Sjöblom, Markus; Flemström, Gunnar

Ingår i J Physiology and Pharmacology, s. 671, 2001

Peripheral melatonin mediates stimulation of duodenal mucosal bicarbonate secretion

Sjöblom, Markus; Jedstedt, Gunilla; Flemström, Gunnar

Ingår i J Clin Investigation, s. 625, 2001

Peripheral melatonin mediates neural stimulation of duodenal mucosal bicarbonate secretion

Sjöblom, Markus; Jedstedt, Gunilla; Flemström, Gunnar

Ingår i Journal of Clinical Investigation, s. 625-633, 2001

Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions

Roos, Carl; Dahlgren, David; Sjögren, Erik; Sjöblom, Markus et al.

Ingår i European journal of pharmaceutics and biopharmaceutics

Endoplasmic reticulum stress in the pathogenesis of chemotherapy-induced mucositis: Physiological mechanisms and therapeutic implications

Heindryckx, Femke; Sjöblom, Markus

Ingår i Acta Physiologica, 2024

• DOI för Endoplasmic reticulum stress in the pathogenesis of chemotherapy-induced mucositis: Physiological mechanisms and therapeutic implications
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Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies

Dahlgren, David; Sjöblom, Markus; Hellström, Per M.; Lennernäs, Hans

Ingår i Frontiers in Pharmacology, 2021

• DOI för Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
• Ladda ner fulltext (pdf) av Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies

Duodenal epithelial sensing of luminal acid: role of carbonic anhydrases

Sjöblom, Markus

Ingår i Acta Physiologica, s. 85-95, 2011

• DOI för Duodenal epithelial sensing of luminal acid: role of carbonic anhydrases

Gastroduodenal Bicarbonate Secretion

Seidler, Ursula; Sjöblom, Markus

Ingår i Physiology of the Gastrointestinal Tract, s. 1311-1340, Academic, 2012

Duodenal Protection: Influence of melatonin and other intestinal transmitters on duodenal bicarbonate secretion and enterocyte signaling. In: Mechanisms and Consequences of Proton Transport. Eds T. Urushidani et al.In: Mechanisms and Consequences of Proton Transport. Eds T. Urushidani et al.

Flemström, Gunnar; Sjöblom, Markus

Kluwer Academic Publishers, Boston/Dordrecht/London. 2002, pp.115-122., 2002

Some duodenal functions and their dependence on luminal NaCl

Pihl, Liselotte; Sjöblom, Markus; Nylander, Olof

Pharmacological inhibition of PERK during early carcinogenesis restrains tumor progression and remodels the tumor microenvironment in hepatocellular carcinoma

Khaled, Jaafar; Kopsida, Maria; Payo Serafín, Tania; Sennefelt Nyman, Sofi et al.