Sara Rinne

Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26

Rinne, Sara S.; Abouzayed, Ayman; Gagnon, Katherine; Tolmachev, Vladimir et al.

Part of Scientific Reports, 2021

• DOI for Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26
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Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules

Rinne, Sara S.; Xu, Tianqi; Leitao, Charles Dahlsson; Stahl, Stefan et al.

Part of International Journal of Molecular Sciences, 2020

• DOI for Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules
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Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

Rinne, Sara S.; Leitao, Charles Dahlsson; Saleh-nihad, Zahra; Mitran, Bogdan et al.

Part of International Journal of Molecular Sciences, 2020

• DOI for Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules
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Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111

Rinne, Sara S.; Leitao, Charles Dahlsson; Mitran, Bogdan; Bass, Tarek Z. et al.

Part of Scientific Reports, 2019

• DOI for Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111
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Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Altai, Mohamed; Leitao, Charles Dahlsson; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

Part of Cells, 2018

• DOI for Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs
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Optimization of affibody molecule for imaging of HER3 expression: negatively charged metal-chelator complex increases imaging contrast

Rinne, Sara S.; Mitran, Bogdan; Leitao, C. Dahlsson; Ståhl, S. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

Pretargeted 177Lu/225Ac combination therapy of colorectal cancer

Rinne, Sara S.; Salehi, Niloufar; Vaughn, Brett A.; Vargas, Daniela Burnes et al.

Part of Theranostics, p. 5898-5910, 2026

• DOI for Pretargeted 177Lu/225Ac combination therapy of colorectal cancer
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Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Rinne, Sara S.; Yin, Wen; Li, Ruonan; Ding, Haozhong et al.

Part of ACS Pharmacology & Translational Science, p. 3872-3885, 2025

• DOI for Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents
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Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Zhang, Jie; Rinne, Sara S.; Yin, Wen; Leitao, Charles Dahlsson et al.

Part of ACS Pharmacology & Translational Science, p. 3228-3240, 2024

• DOI for Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
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Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Lundmark, Fanny; Vorobyeva, Anzhelika; Liu, Yongsheng; Lindbo, Sarah et al.

Part of Molecular Medicine Reports, 2024

• DOI for Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker
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Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Lundmark, Fanny; Abouzayed, Ayman; Rinne, Sara S.; Timofeev, Vasiliy et al.

Part of Cancers, 2023

• DOI for Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
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Pretargeted 177Lu/225Ac combination therapy of colorectal cancer

Rinne, Sara S.; Salehi, Niloufar; Vaughn, Brett A.; Vargas, Daniela Burnes et al.

Part of Theranostics, p. 5898-5910, 2026

• DOI for Pretargeted 177Lu/225Ac combination therapy of colorectal cancer
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Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Rinne, Sara S.; Yin, Wen; Li, Ruonan; Ding, Haozhong et al.

Part of ACS Pharmacology & Translational Science, p. 3872-3885, 2025

• DOI for Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents
• Download full text (pdf) of Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Zhang, Jie; Rinne, Sara S.; Yin, Wen; Leitao, Charles Dahlsson et al.

Part of ACS Pharmacology & Translational Science, p. 3228-3240, 2024

• DOI for Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
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Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Lundmark, Fanny; Vorobyeva, Anzhelika; Liu, Yongsheng; Lindbo, Sarah et al.

Part of Molecular Medicine Reports, 2024

• DOI for Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker
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Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Lundmark, Fanny; Abouzayed, Ayman; Rinne, Sara S.; Timofeev, Vasiliy et al.

Part of Cancers, 2023

• DOI for Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
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Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors

Chernov, Vladimir; Rybina, Anastasiya; Zelchan, Roman; Medvedeva, Anna et al.

Part of Cancers, 2023

• DOI for Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors
• Download full text (pdf) of Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors

Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model

Xu, Tianqi; Schulga, Alexey; Konovalova, Elena; Rinne, Sara S. et al.

Part of International Journal of Molecular Sciences, 2023

• DOI for Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model
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Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Lundmark, Fanny; Olanders, Gustav; Rinne, Sara Sophie; Abouzayed, Ayman et al.

Part of Pharmaceutics, 2022

• DOI for Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
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Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules

Rinne, Sara S.; Yin, Wen; Borras, Anna Mestre; Abouzayed, Ayman et al.

Part of Biomedicines, 2022

• DOI for Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules
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Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT

Liu, Yongsheng; Yu, Shengze; Xu, Tianqi; Bodenko, Vitalina et al.

Part of Pharmaceutics, 2022

• DOI for Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT
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Preclinical Evaluation of ^99mTc-Labeled GRPR Antagonists maSSS/SES-PEG₂-RM26 for Imaging of Prostate Cancer

Abouzayed, Ayman; Rinne, Sara S.; Sabahnoo, Hamideh; Sörensen, Jens et al.

Part of Pharmaceutics, 2021

• DOI for Preclinical Evaluation of ^99mTc-Labeled GRPR Antagonists maSSS/SES-PEG₂-RM26 for Imaging of Prostate Cancer
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The Use of a Non-Conventional Long-Lived Gallium Radioisotope ⁶⁶Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR: 2377 Affibody Molecule

Oroujeni, Maryam; Xu, Tianqi; Gagnon, Katherine; Rinne, Sara S. et al.

Part of Pharmaceutics, 2021

• DOI for The Use of a Non-Conventional Long-Lived Gallium Radioisotope ⁶⁶Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR: 2377 Affibody Molecule
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Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1

Deyev, Sergey M.; Xu, Tianqi; Liu, Yongsheng; Schulga, Alexey et al.

Part of Cancers, 2021

• DOI for Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1
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HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers

Rinne, Sara S.; Dahlsson Leitao, Charles; Abouzayed, Ayman; Vorobyeva, Anzhelika et al.

Part of Cancers, p. 4791-4791, 2021

• DOI for HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers
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Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26

Rinne, Sara S.; Abouzayed, Ayman; Gagnon, Katherine; Tolmachev, Vladimir et al.

Part of Scientific Reports, 2021

• DOI for Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26
• Download full text (pdf) of Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26

Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake

Oroujeni, Maryam; Rinne, Sara S.; Vorobyeva, Anzhelika; Loftenius, Annika et al.

Part of International Journal of Molecular Sciences, 2021

• DOI for Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake
• Download full text (pdf) of Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake

Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer

Abouzayed, Ayman; Tano, Hanna; Nagy, Abel; Rinne, Sara S. et al.

Part of Pharmaceutics, 2020

• DOI for Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer
• Download full text (pdf) of Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer

Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules

Rinne, Sara S.; Xu, Tianqi; Leitao, Charles Dahlsson; Stahl, Stefan et al.

Part of International Journal of Molecular Sciences, 2020

• DOI for Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules
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Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Lundmark, Fanny; Abouzayed, Ayman; Mitran, Bogdan; Rinne, Sara S. et al.

Part of Pharmaceutics, 2020

• DOI for Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model
• Download full text (pdf) of Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model.

Leitao, Charles Dahlsson; Rinne, Sara S.; Altai, Mohamed; Vorontsova, Olga et al.

Part of Pharmaceutics, 2020

• DOI for Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model.
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Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

Baun, Christina; Mitran, Bogdan; Rinne, Sara S.; Dam, Johan H. et al.

Part of Molecules, 2020

• DOI for Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer
• Download full text (pdf) of Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein

Vorobyeva, Anzhelika; Oroujeni, Maryam; Lindbo, Sarah; Hober, Sophia et al.

Part of Molecules, 2020

• DOI for Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein
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On the prevention of kidney uptake of radiolabeled DARPins

Altai, Mohamed; Garousi, Javad; Rinne, Sara S.; Schulga, Alexey et al.

Part of EJNMMI Research, 2020

• DOI for On the prevention of kidney uptake of radiolabeled DARPins
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Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

Rinne, Sara S.; Leitao, Charles Dahlsson; Saleh-nihad, Zahra; Mitran, Bogdan et al.

Part of International Journal of Molecular Sciences, 2020

• DOI for Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules
• Download full text (pdf) of Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

Vorobyeva, Anzhelika; Konovalova, Elena; Xu, Tianqi; Schulga, Alexey et al.

Part of International Journal of Molecular Sciences, 2020

• DOI for Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1
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Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates

Ding, Haozhong; Altai, Mohamed; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

Part of Cancers, 2019

• DOI for Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates
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Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of ⁶⁸Ga-Labeled Tracers

Dahlsson Leitao, Charles; Rinne, Sara S.; Mitran, Bogdan; Vorobyeva, Anzhelika et al.

Part of International Journal of Molecular Sciences, 2019

• DOI for Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of ⁶⁸Ga-Labeled Tracers
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Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111

Rinne, Sara S.; Leitao, Charles Dahlsson; Mitran, Bogdan; Bass, Tarek Z. et al.

Part of Scientific Reports, 2019

• DOI for Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111
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Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Abouzayed, Ayman; Yim, Cheng-Bin; Mitran, Bogdan; Rinne, Sara S. et al.

Part of Pharmaceutics, 2019

• DOI for Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer
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Increase in negative charge of ⁶⁸Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules

Rinne, Sara S.; Leitao, Charles Dahlsson; Gentry, Joshua; Mitran, Bogdan et al.

Part of Scientific Reports, 2019

• DOI for Increase in negative charge of ⁶⁸Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules
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Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26

Mitran, Bogdan; Thisgaard, Helge; Rinne, Sara S.; Dam, Johan Hygum et al.

Part of Scientific Reports, 2019

• DOI for Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26
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Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake

Rosestedt, Maria; Andersson, Ken G.; Rinne, Sara S.; Leitao, Charles Dahlsson et al.

Part of Scientific Reports, 2019

• DOI for Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake
• Download full text (pdf) of Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake

Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging

Vorobyeva, Anzhelika; Schulga, Alexey; Rinne, Sara S.; Günther, Tyran et al.

Part of International Journal of Molecular Sciences, 2019

• DOI for Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging
• Download full text (pdf) of Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging

Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

Vorobyeva, Anzhelika; Schulga, Alexey; Konovalova, Elena; Güler, Rezan et al.

Part of International Journal of Oncology, p. 1209-1220, 2019

• DOI for Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2
• Download full text (pdf) of Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Mitran, Bogdan; Varasteh, Zohreh; Abouzayed, Ayman; Rinne, Sara S. et al.

Part of Cancers, 2019

• DOI for Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer
• Download full text (pdf) of Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

Mitran, Bogdan; Rinne, Sara S.; Konijnenberg, Mark W.; Maina, Theodosia et al.

Part of International Journal of Cancer, p. 3347-3358, 2019

• DOI for Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26
• Download full text (pdf) of Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab

Orlova, Anna; Bass, Tarek Z.; Rinne, Sara S.; Leitao, Charles Dahlsson et al.

Part of Molecular Pharmaceutics, p. 3394-3403, 2018

• DOI for Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab

Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Altai, Mohamed; Leitao, Charles Dahlsson; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

Part of Cells, 2018

• DOI for Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs
• Download full text (pdf) of Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Mitran, Bogdan; Güler, Rezan; Roche, Francis P.; Lindström, Elin et al.

Part of Theranostics, p. 4462-4476, 2018

• DOI for Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
• Download full text (pdf) of Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy

Vorobyeva, Anzhelika; Westerlund, Kristina; Mitran, Bogdan; Altai, Mohamed et al.

Part of Scientific Reports, 2018

• DOI for Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy
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Development of a PET Imaging Approach for Selection of Patients for Affibody-Based PNA-Mediated Pretargeted Radionuclide Therapy

Vorobyeva, Anzhelika; Westerlund, K.; Mitran, Bogdan; Altai, Mohamed et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2018

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Optimization of molecular design of Ga-68-labeled affibody molecule for PET imaging of HER3 expression

Rinne, Sara S.; Mitran, Bogdan; Vorobyeva, Anzhelika; Leitao, C. Dahlsson et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2018

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Imaging contrast of HER3 expression using monomeric affibody-based imaging probe can be improved by co-injection of affibody trimer

Orlova, Anna; Rosestedt, Maria; Rinne, Sara S.; Mitran, Bogdan et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2018

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Selection of optimal macrocyclic chelator for high contrast PET imaging of gastrin releasing peptide receptor using cobalt-labeled bombesin antagonist RM26

Mitran, Bogdan; Thisgaard, H.; Rinne, Sara S.; Rosenström, Ulrika et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2018

GRPR-targeted radiotherapy using the Lu-177-labeled GRPR-antagonist DOTAGA-PEG(2)-RM26

Mitran, Bogdan; Rinne, Sara S.; Azamy, F.; Vorobyeva, Anzhelika et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2018

Evaluation of radiocobalt-labelled affibody molecule for imaging of human epidermal growth factor receptor 3 expression

Rosestedt, Maria; Andersson, Ken G; Mitran, Bogdan; Rinne, Sara S. et al.

Part of International Journal of Oncology, p. 1765-1774, 2017

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Novel high affinity affibody for radionuclide imaging of VEGFR2 in glioma vasculature: proof-of-principle in murine model

Mitran, Bogdan; Guler, R.; Roche, Francis P.; Lindström, Elin et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

GRPR-Targeted Radiotherapy: Influence of Chelator on Labeling and Biodistribution of Four Lu-177-Labeled Analogues of the GRPR-Antagonist PEG2-RM26

Orlova, Anna; Mitran, Bogdan; Maina, T.; Nock, B. A. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

Optimization of affibody molecule for imaging of HER3 expression: negatively charged metal-chelator complex increases imaging contrast

Rinne, Sara S.; Mitran, Bogdan; Leitao, C. Dahlsson; Ståhl, S. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology

Rinne, Sara S.; Orlova, Anna; Tolmachev, Vladimir

Part of International Journal of Molecular Sciences, 2021

• DOI for PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology
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Affibody-Based Molecular Imaging and Targeted Therapy of HER3-Expressing Cancer

Rinne, Sara Sophie

2022

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