Sara Rinne

Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26

Rinne, Sara S.; Abouzayed, Ayman; Gagnon, Katherine; Tolmachev, Vladimir et al.

Ingår i Scientific Reports, 2021

• DOI för Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26
• Ladda ner fulltext (pdf) av Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26

Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules

Rinne, Sara S.; Xu, Tianqi; Leitao, Charles Dahlsson; Stahl, Stefan et al.

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules
• Ladda ner fulltext (pdf) av Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules

Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

Rinne, Sara S.; Leitao, Charles Dahlsson; Saleh-nihad, Zahra; Mitran, Bogdan et al.

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules
• Ladda ner fulltext (pdf) av Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111

Rinne, Sara S.; Leitao, Charles Dahlsson; Mitran, Bogdan; Bass, Tarek Z. et al.

Ingår i Scientific Reports, 2019

• DOI för Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111
• Ladda ner fulltext (pdf) av Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111

Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Altai, Mohamed; Leitao, Charles Dahlsson; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

Ingår i Cells, 2018

• DOI för Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs
• Ladda ner fulltext (pdf) av Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Optimization of affibody molecule for imaging of HER3 expression: negatively charged metal-chelator complex increases imaging contrast

Rinne, Sara S.; Mitran, Bogdan; Leitao, C. Dahlsson; Ståhl, S. et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2017

Pretargeted 177Lu/225Ac combination therapy of colorectal cancer

Rinne, Sara S.; Salehi, Niloufar; Vaughn, Brett A.; Vargas, Daniela Burnes et al.

Ingår i Theranostics, s. 5898-5910, 2026

• DOI för Pretargeted 177Lu/225Ac combination therapy of colorectal cancer
• Ladda ner fulltext (pdf) av Pretargeted 177Lu/225Ac combination therapy of colorectal cancer

Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Rinne, Sara S.; Yin, Wen; Li, Ruonan; Ding, Haozhong et al.

Ingår i ACS Pharmacology & Translational Science, s. 3872-3885, 2025

• DOI för Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents
• Ladda ner fulltext (pdf) av Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Zhang, Jie; Rinne, Sara S.; Yin, Wen; Leitao, Charles Dahlsson et al.

Ingår i ACS Pharmacology & Translational Science, s. 3228-3240, 2024

• DOI för Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
• Ladda ner fulltext (pdf) av Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Lundmark, Fanny; Vorobyeva, Anzhelika; Liu, Yongsheng; Lindbo, Sarah et al.

Ingår i Molecular Medicine Reports, 2024

• DOI för Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker
• Ladda ner fulltext (pdf) av Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Lundmark, Fanny; Abouzayed, Ayman; Rinne, Sara S.; Timofeev, Vasiliy et al.

Ingår i Cancers, 2023

• DOI för Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
• Ladda ner fulltext (pdf) av Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Pretargeted 177Lu/225Ac combination therapy of colorectal cancer

Rinne, Sara S.; Salehi, Niloufar; Vaughn, Brett A.; Vargas, Daniela Burnes et al.

Ingår i Theranostics, s. 5898-5910, 2026

• DOI för Pretargeted 177Lu/225Ac combination therapy of colorectal cancer
• Ladda ner fulltext (pdf) av Pretargeted 177Lu/225Ac combination therapy of colorectal cancer

Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Rinne, Sara S.; Yin, Wen; Li, Ruonan; Ding, Haozhong et al.

Ingår i ACS Pharmacology & Translational Science, s. 3872-3885, 2025

• DOI för Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents
• Ladda ner fulltext (pdf) av Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Zhang, Jie; Rinne, Sara S.; Yin, Wen; Leitao, Charles Dahlsson et al.

Ingår i ACS Pharmacology & Translational Science, s. 3228-3240, 2024

• DOI för Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
• Ladda ner fulltext (pdf) av Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Lundmark, Fanny; Vorobyeva, Anzhelika; Liu, Yongsheng; Lindbo, Sarah et al.

Ingår i Molecular Medicine Reports, 2024

• DOI för Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker
• Ladda ner fulltext (pdf) av Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker

Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Lundmark, Fanny; Abouzayed, Ayman; Rinne, Sara S.; Timofeev, Vasiliy et al.

Ingår i Cancers, 2023

• DOI för Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
• Ladda ner fulltext (pdf) av Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors

Chernov, Vladimir; Rybina, Anastasiya; Zelchan, Roman; Medvedeva, Anna et al.

Ingår i Cancers, 2023

• DOI för Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors
• Ladda ner fulltext (pdf) av Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors

Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model

Xu, Tianqi; Schulga, Alexey; Konovalova, Elena; Rinne, Sara S. et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model
• Ladda ner fulltext (pdf) av Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model

Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Lundmark, Fanny; Olanders, Gustav; Rinne, Sara Sophie; Abouzayed, Ayman et al.

Ingår i Pharmaceutics, 2022

• DOI för Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
• Ladda ner fulltext (pdf) av Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules

Rinne, Sara S.; Yin, Wen; Borras, Anna Mestre; Abouzayed, Ayman et al.

Ingår i Biomedicines, 2022

• DOI för Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules
• Ladda ner fulltext (pdf) av Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules

Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT

Liu, Yongsheng; Yu, Shengze; Xu, Tianqi; Bodenko, Vitalina et al.

Ingår i Pharmaceutics, 2022

• DOI för Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT
• Ladda ner fulltext (pdf) av Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT

Preclinical Evaluation of ^99mTc-Labeled GRPR Antagonists maSSS/SES-PEG₂-RM26 for Imaging of Prostate Cancer

Abouzayed, Ayman; Rinne, Sara S.; Sabahnoo, Hamideh; Sörensen, Jens et al.

Ingår i Pharmaceutics, 2021

• DOI för Preclinical Evaluation of ^99mTc-Labeled GRPR Antagonists maSSS/SES-PEG₂-RM26 for Imaging of Prostate Cancer
• Ladda ner fulltext (pdf) av Preclinical Evaluation of ^99mTc-Labeled GRPR Antagonists maSSS/SES-PEG₂-RM26 for Imaging of Prostate Cancer

The Use of a Non-Conventional Long-Lived Gallium Radioisotope ⁶⁶Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR: 2377 Affibody Molecule

Oroujeni, Maryam; Xu, Tianqi; Gagnon, Katherine; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2021

• DOI för The Use of a Non-Conventional Long-Lived Gallium Radioisotope ⁶⁶Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR: 2377 Affibody Molecule
• Ladda ner fulltext (pdf) av The Use of a Non-Conventional Long-Lived Gallium Radioisotope ⁶⁶Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR: 2377 Affibody Molecule

Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1

Deyev, Sergey M.; Xu, Tianqi; Liu, Yongsheng; Schulga, Alexey et al.

Ingår i Cancers, 2021

• DOI för Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1
• Ladda ner fulltext (pdf) av Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1

HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers

Rinne, Sara S.; Dahlsson Leitao, Charles; Abouzayed, Ayman; Vorobyeva, Anzhelika et al.

Ingår i Cancers, s. 4791-4791, 2021

• DOI för HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers
• Ladda ner fulltext (pdf) av HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers

Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26

Rinne, Sara S.; Abouzayed, Ayman; Gagnon, Katherine; Tolmachev, Vladimir et al.

Ingår i Scientific Reports, 2021

• DOI för Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26
• Ladda ner fulltext (pdf) av Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26

Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake

Oroujeni, Maryam; Rinne, Sara S.; Vorobyeva, Anzhelika; Loftenius, Annika et al.

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake
• Ladda ner fulltext (pdf) av Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake

Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer

Abouzayed, Ayman; Tano, Hanna; Nagy, Abel; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2020

• DOI för Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer
• Ladda ner fulltext (pdf) av Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer

Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules

Rinne, Sara S.; Xu, Tianqi; Leitao, Charles Dahlsson; Stahl, Stefan et al.

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules
• Ladda ner fulltext (pdf) av Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules

Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Lundmark, Fanny; Abouzayed, Ayman; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2020

• DOI för Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model
• Ladda ner fulltext (pdf) av Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model.

Leitao, Charles Dahlsson; Rinne, Sara S.; Altai, Mohamed; Vorontsova, Olga et al.

Ingår i Pharmaceutics, 2020

• DOI för Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model.
• Ladda ner fulltext (pdf) av Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model.

Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

Baun, Christina; Mitran, Bogdan; Rinne, Sara S.; Dam, Johan H. et al.

Ingår i Molecules, 2020

• DOI för Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer
• Ladda ner fulltext (pdf) av Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein

Vorobyeva, Anzhelika; Oroujeni, Maryam; Lindbo, Sarah; Hober, Sophia et al.

Ingår i Molecules, 2020

• DOI för Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein
• Ladda ner fulltext (pdf) av Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein

On the prevention of kidney uptake of radiolabeled DARPins

Altai, Mohamed; Garousi, Javad; Rinne, Sara S.; Schulga, Alexey et al.

Ingår i EJNMMI Research, 2020

• DOI för On the prevention of kidney uptake of radiolabeled DARPins
• Ladda ner fulltext (pdf) av On the prevention of kidney uptake of radiolabeled DARPins

Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

Rinne, Sara S.; Leitao, Charles Dahlsson; Saleh-nihad, Zahra; Mitran, Bogdan et al.

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules
• Ladda ner fulltext (pdf) av Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

Vorobyeva, Anzhelika; Konovalova, Elena; Xu, Tianqi; Schulga, Alexey et al.

Ingår i International Journal of Molecular Sciences, 2020

• DOI för Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1
• Ladda ner fulltext (pdf) av Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates

Ding, Haozhong; Altai, Mohamed; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

Ingår i Cancers, 2019

• DOI för Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates
• Ladda ner fulltext (pdf) av Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates

Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of ⁶⁸Ga-Labeled Tracers

Dahlsson Leitao, Charles; Rinne, Sara S.; Mitran, Bogdan; Vorobyeva, Anzhelika et al.

Ingår i International Journal of Molecular Sciences, 2019

• DOI för Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of ⁶⁸Ga-Labeled Tracers
• Ladda ner fulltext (pdf) av Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of ⁶⁸Ga-Labeled Tracers

Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111

Rinne, Sara S.; Leitao, Charles Dahlsson; Mitran, Bogdan; Bass, Tarek Z. et al.

Ingår i Scientific Reports, 2019

• DOI för Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111
• Ladda ner fulltext (pdf) av Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111

Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Abouzayed, Ayman; Yim, Cheng-Bin; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2019

• DOI för Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer
• Ladda ner fulltext (pdf) av Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Increase in negative charge of ⁶⁸Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules

Rinne, Sara S.; Leitao, Charles Dahlsson; Gentry, Joshua; Mitran, Bogdan et al.

Ingår i Scientific Reports, 2019

• DOI för Increase in negative charge of ⁶⁸Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules
• Ladda ner fulltext (pdf) av Increase in negative charge of ⁶⁸Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules

Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26

Mitran, Bogdan; Thisgaard, Helge; Rinne, Sara S.; Dam, Johan Hygum et al.

Ingår i Scientific Reports, 2019

• DOI för Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26
• Ladda ner fulltext (pdf) av Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26

Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake

Rosestedt, Maria; Andersson, Ken G.; Rinne, Sara S.; Leitao, Charles Dahlsson et al.

Ingår i Scientific Reports, 2019

• DOI för Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake
• Ladda ner fulltext (pdf) av Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake

Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging

Vorobyeva, Anzhelika; Schulga, Alexey; Rinne, Sara S.; Günther, Tyran et al.

Ingår i International Journal of Molecular Sciences, 2019

• DOI för Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging
• Ladda ner fulltext (pdf) av Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging

Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

Vorobyeva, Anzhelika; Schulga, Alexey; Konovalova, Elena; Güler, Rezan et al.

Ingår i International Journal of Oncology, s. 1209-1220, 2019

• DOI för Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2
• Ladda ner fulltext (pdf) av Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Mitran, Bogdan; Varasteh, Zohreh; Abouzayed, Ayman; Rinne, Sara S. et al.

Ingår i Cancers, 2019

• DOI för Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer
• Ladda ner fulltext (pdf) av Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

Mitran, Bogdan; Rinne, Sara S.; Konijnenberg, Mark W.; Maina, Theodosia et al.

Ingår i International Journal of Cancer, s. 3347-3358, 2019

• DOI för Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26
• Ladda ner fulltext (pdf) av Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab

Orlova, Anna; Bass, Tarek Z.; Rinne, Sara S.; Leitao, Charles Dahlsson et al.

Ingår i Molecular Pharmaceutics, s. 3394-3403, 2018

• DOI för Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab

Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Altai, Mohamed; Leitao, Charles Dahlsson; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

Ingår i Cells, 2018

• DOI för Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs
• Ladda ner fulltext (pdf) av Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Mitran, Bogdan; Güler, Rezan; Roche, Francis P.; Lindström, Elin et al.

Ingår i Theranostics, s. 4462-4476, 2018

• DOI för Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
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Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy

Vorobyeva, Anzhelika; Westerlund, Kristina; Mitran, Bogdan; Altai, Mohamed et al.

Ingår i Scientific Reports, 2018

• DOI för Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy
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Development of a PET Imaging Approach for Selection of Patients for Affibody-Based PNA-Mediated Pretargeted Radionuclide Therapy

Vorobyeva, Anzhelika; Westerlund, K.; Mitran, Bogdan; Altai, Mohamed et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2018

• DOI för Development of a PET Imaging Approach for Selection of Patients for Affibody-Based PNA-Mediated Pretargeted Radionuclide Therapy

Optimization of molecular design of Ga-68-labeled affibody molecule for PET imaging of HER3 expression

Rinne, Sara S.; Mitran, Bogdan; Vorobyeva, Anzhelika; Leitao, C. Dahlsson et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2018

• DOI för Optimization of molecular design of Ga-68-labeled affibody molecule for PET imaging of HER3 expression

Imaging contrast of HER3 expression using monomeric affibody-based imaging probe can be improved by co-injection of affibody trimer

Orlova, Anna; Rosestedt, Maria; Rinne, Sara S.; Mitran, Bogdan et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2018

• DOI för Imaging contrast of HER3 expression using monomeric affibody-based imaging probe can be improved by co-injection of affibody trimer

Selection of optimal macrocyclic chelator for high contrast PET imaging of gastrin releasing peptide receptor using cobalt-labeled bombesin antagonist RM26

Mitran, Bogdan; Thisgaard, H.; Rinne, Sara S.; Rosenström, Ulrika et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2018

GRPR-targeted radiotherapy using the Lu-177-labeled GRPR-antagonist DOTAGA-PEG(2)-RM26

Mitran, Bogdan; Rinne, Sara S.; Azamy, F.; Vorobyeva, Anzhelika et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2018

Evaluation of radiocobalt-labelled affibody molecule for imaging of human epidermal growth factor receptor 3 expression

Rosestedt, Maria; Andersson, Ken G; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i International Journal of Oncology, s. 1765-1774, 2017

• DOI för Evaluation of radiocobalt-labelled affibody molecule for imaging of human epidermal growth factor receptor 3 expression
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Novel high affinity affibody for radionuclide imaging of VEGFR2 in glioma vasculature: proof-of-principle in murine model

Mitran, Bogdan; Guler, R.; Roche, Francis P.; Lindström, Elin et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2017

GRPR-Targeted Radiotherapy: Influence of Chelator on Labeling and Biodistribution of Four Lu-177-Labeled Analogues of the GRPR-Antagonist PEG2-RM26

Orlova, Anna; Mitran, Bogdan; Maina, T.; Nock, B. A. et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2017

Optimization of affibody molecule for imaging of HER3 expression: negatively charged metal-chelator complex increases imaging contrast

Rinne, Sara S.; Mitran, Bogdan; Leitao, C. Dahlsson; Ståhl, S. et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2017

PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology

Rinne, Sara S.; Orlova, Anna; Tolmachev, Vladimir

Ingår i International Journal of Molecular Sciences, 2021

• DOI för PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology
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Affibody-Based Molecular Imaging and Targeted Therapy of HER3-Expressing Cancer

Rinne, Sara Sophie

2022

• Ladda ner fulltext 1 (pdf) av Affibody-Based Molecular Imaging and Targeted Therapy of HER3-Expressing Cancer
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