Gudmar Lönnerholm

Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Enblad, Anna Pia; Krali, Olga; Gezelius, Henrik; Lundmark, Anders et al.

Part of HemaSphere, 2025

• DOI for Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
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Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling

Orgueira, Adrian Mosquera; Krali, Olga; Miguez, Carlos Perez; Raindo, Andres Peleteiro et al.

Part of Clinical Epigenetics, 2024

• DOI for Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling
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Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia

Krali, Olga; Marincevic-Zuniga, Yanara; Arvidsson, Gustav; Enblad, Anna Pia et al.

Part of npj Precision Oncology, 2023

• DOI for Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia
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Increased MYB alternative promoter usage is associated with relapse in acute lymphoblastic leukemia

Fehr, André; Arvidsson, Gustav; Nordlund, Jessica; Lönnerholm, Gudmar et al.

Part of Genes, Chromosomes and Cancer, p. 597-606, 2023

• DOI for Increased MYB alternative promoter usage is associated with relapse in acute lymphoblastic leukemia
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RAG1 co-expression signature identifies ETV6-RUNX1-like B-cell precursor acute lymphoblastic leukemia in children

Chen, Dongfeng; Camponeschi, Alessandro; Nordlund, Jessica; Marincevic-Zuniga, Yanara et al.

Part of Cancer Medicine, p. 3997-4003, 2021

• DOI for RAG1 co-expression signature identifies ETV6-RUNX1-like B-cell precursor acute lymphoblastic leukemia in children
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Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Enblad, Anna Pia; Krali, Olga; Gezelius, Henrik; Lundmark, Anders et al.

Part of HemaSphere, 2025

• DOI for Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
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Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling

Orgueira, Adrian Mosquera; Krali, Olga; Miguez, Carlos Perez; Raindo, Andres Peleteiro et al.

Part of Clinical Epigenetics, 2024

• DOI for Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling
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Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia

Krali, Olga; Marincevic-Zuniga, Yanara; Arvidsson, Gustav; Enblad, Anna Pia et al.

Part of npj Precision Oncology, 2023

• DOI for Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia
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Increased MYB alternative promoter usage is associated with relapse in acute lymphoblastic leukemia

Fehr, André; Arvidsson, Gustav; Nordlund, Jessica; Lönnerholm, Gudmar et al.

Part of Genes, Chromosomes and Cancer, p. 597-606, 2023

• DOI for Increased MYB alternative promoter usage is associated with relapse in acute lymphoblastic leukemia
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RAG1 co-expression signature identifies ETV6-RUNX1-like B-cell precursor acute lymphoblastic leukemia in children

Chen, Dongfeng; Camponeschi, Alessandro; Nordlund, Jessica; Marincevic-Zuniga, Yanara et al.

Part of Cancer Medicine, p. 3997-4003, 2021

• DOI for RAG1 co-expression signature identifies ETV6-RUNX1-like B-cell precursor acute lymphoblastic leukemia in children
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Mutational patterns and clonal evolution from diagnosis to relapse in pediatric acute lymphoblastic leukemia

Sayyab, Shumaila; Lundmark, Anders; Larsson, Malin; Ringner, Markus et al.

Part of Scientific Reports, 2021

• DOI for Mutational patterns and clonal evolution from diagnosis to relapse in pediatric acute lymphoblastic leukemia
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The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Duran-Ferrer, Marti; Clot, Guillem; Nadeu, Ferran; Beekman, Renee et al.

Part of Nature Cancer, p. 1066-1081, 2020

• DOI for The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Refined detection and phasing of structural aberrations in pediatric acute lymphoblastic leukemia by linked-read whole-genome sequencing

Nordlund, Jessica; Marincevic-Zuniga, Yanara; Cavelier, Lucia; Raine, Amanda et al.

Part of Scientific Reports, 2020

• DOI for Refined detection and phasing of structural aberrations in pediatric acute lymphoblastic leukemia by linked-read whole-genome sequencing
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Overexpression of chromatin remodeling and tyrosine kinase genes in iAMP21-positive acute lymphoblastic leukemia

Ivanov Öfverholm, I.; Zachariadis, V.; Taylan, F.; Marincevic-Zuniga, Yanara et al.

Part of Leukemia and Lymphoma, p. 604-613, 2020

• DOI for Overexpression of chromatin remodeling and tyrosine kinase genes in iAMP21-positive acute lymphoblastic leukemia
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CD99 expression is strongly associated with clinical outcome in children with B-cell precursor acute lymphoblastic leukaemia

Chen, Dongfeng; Camponeschi, Alessandro; Wu, Qingqing; Gerasimcik, Natalija et al.

Part of British Journal of Haematology, p. 418-423, 2019

• DOI for CD99 expression is strongly associated with clinical outcome in children with B-cell precursor acute lymphoblastic leukaemia

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

Borssen, Magnus; Nordlund, Jessica; Haider, Zahra; Landfors, Mattias et al.

Part of Clinical Epigenetics, 2018

• DOI for DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia
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CD27 expression and its association with clinical outcome in children and adults with pro-B acute lymphoblastic leukemia

Chen, D.; Gerasimcik, N.; Camponeschi, A.; Tan, Y. et al.

Part of Blood Cancer Journal, 2017

• DOI for CD27 expression and its association with clinical outcome in children and adults with pro-B acute lymphoblastic leukemia
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Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles

Marincevic-Zuniga, Yanara; Dahlberg, Johan; Nilsson, Sara; Raine, Amanda et al.

Part of Journal of Hematology & Oncology, 2017

• DOI for Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles
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DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands

Wahlberg, Per; Lundmark, Anders; Nordlund, Jessica; Busche, Stephan et al.

Part of Epigenomics, p. 1367-1387, 2016

• DOI for DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands
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Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

Lindqvist, C. Mårten; Lundmark, Anders; Nordlund, Jessica; Freyhult, Eva et al.

Part of Oncotarget, p. 64071-64088, 2016

• DOI for Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array

Marzouka, Nour-al-dain; Nordlund, Jessica; Bäcklin, Christofer L.; Lönnerholm, Gudmar et al.

Part of Bioinformatics, p. 1080-1082, 2016

• DOI for CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array
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PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia

Marincevic-Zuniga, Yanara; Zachariadis, Vasilios; Cavelier, Lucia; Castor, Anders et al.

Part of Haematologica, 2016

• DOI for PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia

The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

Lindqvist, C Mårten; Nordlund, Jessica; Ekman, Diana; Johansson, Anna et al.

Part of Human Mutation, p. 118-128, 2015

• DOI for The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer; Zachariadis, Vasilios; Cavelier, Lucia et al.

Part of Clinical Epigenetics, 2015

• DOI for DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
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Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer L; Wahlberg, Per; Busche, Stephan et al.

Part of Genome Biology, 2013

• DOI for Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

Berglund, Eva C; Lindqvist, Carl Mårten; Hayat, Shahina; Overnäs, Elin et al.

Part of BMC Genomics, p. 856, 2013

• DOI for Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

DNA Methylation Analysis of Bone Marrow Cells at Diagnosis of Acute Lymphoblastic Leukemia and at Remission

Nordlund, Jessica; Milani, Lili; Lundmark, Anders; Lönnerholm, Gudmar et al.

Part of PLOS ONE, 2012

• DOI for DNA Methylation Analysis of Bone Marrow Cells at Diagnosis of Acute Lymphoblastic Leukemia and at Remission
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The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia

Nordlund, Jessica; Backlin, Carin; Wahlberg, Per; Forestier, E. et al.

Part of European Journal of Cancer, 2012

• DOI for The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia

Digital gene expression profiling of primary acute lymphoblastic leukemia cells

Nordlund, Jessica; Kiialainen, Anna; Karlberg, Olof; Berglund, Eva C et al.

Part of Leukemia, p. 1218-1227, 2012

• DOI for Digital gene expression profiling of primary acute lymphoblastic leukemia cells

Response: High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia

Staffas, Anna; Kanduri, Meena; Hovland, Randi; Rosenquist, Richard et al.

Part of Blood, p. 1087-1088, 2012

• DOI for Response: High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia

In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia

Lönnerholm, Gudmar; Thörn, Ingrid; Sundström, Christer; Frost, Britt-Marie et al.

Part of Leukemia Research, p. 472-478, 2011

• DOI for In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia

Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

Staffas, Anna; Kanduri, Meena; Hovland, Randi; Rosenquist, Richard et al.

Part of Blood, p. 5905-5913, 2011

• DOI for Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.

Thörn, Ingrid; Forestier, Erik; Botling, Johan; Thuresson, Britt et al.

Part of British Journal of Haematology, p. 743-753, 2011

• DOI for Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.

The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial

Zachariadis, V.; Gauffin, F.; Kuchinskaya, E.; Heyman, M. et al.

Part of Leukemia, p. 622-628, 2011

• DOI for The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial

DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia

Milani, Lili; Lundmark, Anders; Kiialainen, Anna; Nordlund, Jessica et al.

Part of Blood, p. 1214-1225, 2010

• DOI for DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia

Monitoring minimal residual disease with flow cytometry, antigen-receptor gene rearrangements and fusion transcript quantification in Philadelphia-positive childhood acute lymphoblastic leukemia

Thörn, Ingrid; Botling, Johan; Hermansson, Monica; Lönnerholm, Gudmar et al.

Part of Leukemia Research, p. 1047-1054, 2009

• DOI for Monitoring minimal residual disease with flow cytometry, antigen-receptor gene rearrangements and fusion transcript quantification in Philadelphia-positive childhood acute lymphoblastic leukemia

In vitro cellular drug sensitivity at diagnosis is correlated to minimal residual disease at end of induction therapy in childhood acute lymphoblastic leukemia

Lönnerholm, Gudmar; Thörn, Ingrid; Sundström, Christer; Frost, Britt-Marie et al.

Part of Leukemia Research, p. 46-53, 2009

• DOI for In vitro cellular drug sensitivity at diagnosis is correlated to minimal residual disease at end of induction therapy in childhood acute lymphoblastic leukemia

Vincristine pharmacokinetics in children with Down syndrome

Lönnerholm, Gudmar; Frost, Britt-Marie; Söderhäll, Stefan; de Graaf, Siebold S. N.

Part of Pediatric Blood & Cancer, p. 123-125, 2009

• DOI for Vincristine pharmacokinetics in children with Down syndrome

Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids

Lönnerholm, Gudmar; Nordgren, A.; Frost, Britt-Marie; Jonsson, O. G. et al.

Part of Leukemia, p. 209-212, 2009

• DOI for Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids

Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation

Milani, Lili; Lundmark, Anders; Nordlund, Jessica; Kiialainen, Anna et al.

Part of Genome Research, p. 1-11, 2009

• DOI for Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation

Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia

Palle, Josefine; Frost, Britt-Marie; Petersson, Curt; Hasle, Henrik et al.

Part of Anti-Cancer Drugs, p. 7-14, 2009

• DOI for Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia

Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia

Lönnerholm, Gudmar; Valsecchi, Maria Grazia; De Lorenzo, Paola; Schrappe, Martin et al.

Part of Pediatric Blood & Cancer, p. 596-601, 2009

• DOI for Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia

Bone marrow fibrosis in childhood acute lymphoblastic leukemia correlates to biological factors, treatment response and outcome

Norén-Nyström, Ulrika; Roos, G.; Bergh, A.; Botling, Johan et al.

Part of Leukemia, p. 504-510, 2008

• DOI for Bone marrow fibrosis in childhood acute lymphoblastic leukemia correlates to biological factors, treatment response and outcome

Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia

Lönnerholm, Gudmar; Frost, Britt-Marie; Abrahamsson, Jonas; Behrendtz, Mikael et al.

Part of British Journal of Haematology, p. 616-21, 2008

• DOI for Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia

Dendritic cell regeneration in the bone marrow of children treated for acute lymphoblastic leukaemia

Laane, E.; Björklund, E.; Mazur, J.; Lönnerholm, Gudmar et al.

Part of Scandinavian Journal of Immunology, p. 572-583, 2007

• DOI for Dendritic cell regeneration in the bone marrow of children treated for acute lymphoblastic leukaemia

Etoposide pharmacokinetics in children treated for acute myeloid leukemia

Palle, Josefine; Frost, Britt-Marie; Gustafsson, Göran; Hellebostad, Marit et al.

Part of Anti-Cancer Drugs, p. 1087-1094, 2006

• DOI for Etoposide pharmacokinetics in children treated for acute myeloid leukemia

High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9.

von Bergh, Anne R M; van Drunen, Ellen; van Wering, Elisabeth R; van Zutven, Laura J C M et al.

Part of Genes Chromosomes Cancer, p. 731-9, 2006

Translocation t(1;19) is related to low cellular drug resistance in childhood acute lymphoblastic leukaemia

Frost, B M; Forestier, E; Gustafsson, G; Nygren, Peter et al.

Part of Leukemia, p. 165-169, 2005

• DOI for Translocation t(1;19) is related to low cellular drug resistance in childhood acute lymphoblastic leukaemia

Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage.

Palle, J; Frost, B M; Forestier, E; Gustafsson, G et al.

Part of Br J Haematol, p. 189-98, 2005

Translocation t(12;21) is related to in vitro cellular drug sensitivity to doxorubicin and etoposide in childhood acute lymphoblastic leukemia

Frost, Britt-Marie; Forestier, Erik; Gustafsson, Göran; Nygren, Peter et al.

Part of Blood, p. 2452-7, 2004

• DOI for Translocation t(12;21) is related to in vitro cellular drug sensitivity to doxorubicin and etoposide in childhood acute lymphoblastic leukemia

Pulmonary function after autologous bone marrow transplantation in children: a long-term prospective study

Frisk, Per; Arvidson, Johan; Bratteby, Lars-Eric; Hedenström, Hans et al.

Part of Bone Marrow Transplantation, p. 645-650, 2004

• DOI for Pulmonary function after autologous bone marrow transplantation in children: a long-term prospective study

Growth post transplant. Pubertal development and final height after autologous bone marrow transplantation for acute lymphoblastic leukemia

Frisk, P; Arvidson, J; Gustafsson, J; Lönnerholm, G

Part of Bone Marrow Transplantation, p. 205-210, 2004

Increased in vitro cellular drug resistance is related to poor outcome in high-risk childhood acute lymphoblastic leukaemia

Frost, Britt-Marie; Nygren, Peter; Gustafsson, G; Forestier, E et al.

Part of British Journal of Haematology, p. 376-385, 2003

• DOI for Increased in vitro cellular drug resistance is related to poor outcome in high-risk childhood acute lymphoblastic leukaemia

Pharmacokinetics of Doxorubicin in Children with Acute Lymphoblastic Leukemia: multi-institutional collaborative study

Frost, Britt-Marie; Eksborg, S; Björk, O; Abrahamsson, J et al.

Part of Medical and Pediatric Oncology, p. 329-337, 2002

• DOI for Pharmacokinetics of Doxorubicin in Children with Acute Lymphoblastic Leukemia: multi-institutional collaborative study

In vitro activity of the novel cytotoxic agent CHS 828 in childhood acute leukemia

Frost, Britt-Marie; Lönnerholm, Gudmar; Nygren, Peter; Larsson, Rolf et al.

Part of Anti-Cancer Drugs, p. 735-742, 2002

Cataracts after autologous bone marrow transplantation in children

Frisk, Per; Hagberg, Hans; Mandahl, Agneta; Söderberg, Per et al.

Part of Acta Paediatrica, p. 814-819, 2000

• DOI for Cataracts after autologous bone marrow transplantation in children

Identification of somatic single nucleotide variants inleukemia by targeted sequencing of non-indexed overlapping pools

Lindqvist, Carl Mårten; Dahlberg, Johan; Raine, Amanda; Övernäs, Elin et al.

Refined detection and phasing of structural aberrations in pediatric acute lymphoblastic leukemia with linked-read whole genome sequencing

Nordlund, Jessica; Marincevic-Zuniga, Yanara; Cavelier, Lucia; Raine, Amanda et al.

DNA methylation classification in combination with RNA-sequencing for subtype discovery in pediatric B-cell precursor acute lymphoblastic leukemia

Marincevic-Zuniga, Yanara; Nystedt, Sara; Nilsson, Sara; Almlöf, Jonas Carlsson et al.

Minimal residual disease assessment in childhood acute lymphoblastic leukemia: Results of a Swedish multi-centre study comparing real-time PCR and multi-colour flow cytometry

Thörn, Ingrid; Forestier, Erik; Botling, Johan; Thuresson, Britt et al.

2009