Cardiology

Cardiovascular disease is the most common cause of death and has the highest costs for drug treatment in Sweden. For more than 25 years, the Cardiology research group has been a national centre for research and development in coronary artery disease and its complications, and in recent years stroke prevention during atrial fibrillation.
Description of our research
The research includes register based studies, cell biology research and large clinical trials with patients and healthy controls from many countries.
We aim to improve the treatment and management for the individual patient. We work in the following areas:
- Disease prevalence and mechanisms of disease throughepidemiologic studies of registries and cohort and pathophysiology studies.
- Diagnosis, risk assessment and precision medicine through biomarker studies and studies on imaging based diagnosis.
- Assessment of old (and new) therapies through international clinical trials, independent registry based randomized clinical trials as well as observational registry- and cohort studies.
- Implementation of new therapies through observational registry studies.
Group members
Publications
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DOAC score among patients receiving Vitamin K antagonists
Part of American Heart Journal, 2026
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Heterogeneity of Treatment Effect of DOACs vs Warfarin in Atrial Fibrillation
Part of JACC: Advances, 2026
- DOI for Heterogeneity of Treatment Effect of DOACs vs Warfarin in Atrial Fibrillation
- Download full text (pdf) of Heterogeneity of Treatment Effect of DOACs vs Warfarin in Atrial Fibrillation
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Part of JACC: Advances, 2026
- DOI for Outcomes With Warfarin in Atrial Fibrillation: Individual Patient Data Analysis From Four Randomized Trials
- Download full text (pdf) of Outcomes With Warfarin in Atrial Fibrillation: Individual Patient Data Analysis From Four Randomized Trials
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Part of Circulation, p. 567-575, 2026
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Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
Part of JACC: Advances, 2026
- DOI for Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
- Download full text (pdf) of Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
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Part of Scientific Reports, 2026
- DOI for Comparison of two analytical platforms for quantification of neuroglial biomarkers in blood samples: a single molecule array and an electrochemiluminescence assay
- Download full text (pdf) of Comparison of two analytical platforms for quantification of neuroglial biomarkers in blood samples: a single molecule array and an electrochemiluminescence assay
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Part of European Heart Journal Open, 2026
- DOI for Plasma neurofilament light chain and risk of death and stroke in community-dwelling elderly individuals
- Download full text (pdf) of Plasma neurofilament light chain and risk of death and stroke in community-dwelling elderly individuals
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Part of Thrombosis Research, 2026
- DOI for Complement activation characterizes a high mortality subgroup in pulmonary embolism: An observational proteomic study
- Download full text (pdf) of Complement activation characterizes a high mortality subgroup in pulmonary embolism: An observational proteomic study
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Coronary Computed Tomography Angiography in Prediction of First Coronary Events
Part of Journal of the American Medical Association (JAMA), p. 245-254, 2026
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Part of JACC Cardiovascular Imaging, p. 1110-1119, 2026
- DOI for Association of Lipoprotein(a) With Coronary Atherosclerosis and Cardiovascular Events: Findings From the SCAPIS Cohort
- Download full text (pdf) of Association of Lipoprotein(a) With Coronary Atherosclerosis and Cardiovascular Events: Findings From the SCAPIS Cohort
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Optimizing lipoprotein(a) testing for immediate clinical impact in primary prevention
Part of Atherosclerosis, 2026
- DOI for Optimizing lipoprotein(a) testing for immediate clinical impact in primary prevention
- Download full text (pdf) of Optimizing lipoprotein(a) testing for immediate clinical impact in primary prevention
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First quinquennium completed: highlights from EHJ Open 2025
Part of European Heart Journal Open, 2026
- DOI for First quinquennium completed: highlights from EHJ Open 2025
- Download full text (pdf) of First quinquennium completed: highlights from EHJ Open 2025
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Part of Pharmacoepidemiology and Drug Safety, 2026
- DOI for Methodological Challenges of Emulating a Target Trial to Assess Effectiveness of Timing of PCSK9 Inhibitor Treatment Initiation Post Myocardial Infarction
- Download full text (pdf) of Methodological Challenges of Emulating a Target Trial to Assess Effectiveness of Timing of PCSK9 Inhibitor Treatment Initiation Post Myocardial Infarction
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Sexual functioning after the age of 40 in adults with moderate or severe congenital heart disease
Part of International Journal of Cardiology Congenital Heart Disease, 2026
- DOI for Sexual functioning after the age of 40 in adults with moderate or severe congenital heart disease
- Download full text (pdf) of Sexual functioning after the age of 40 in adults with moderate or severe congenital heart disease
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Part of Scandinavian Cardiovascular Journal, 2026
- DOI for A novel risk score based on exercise capacity to predict prognosis in adults with congenital heart disease
- Download full text (pdf) of A novel risk score based on exercise capacity to predict prognosis in adults with congenital heart disease
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Part of Clinical Chemistry, p. 488-502, 2026
- DOI for Establishing Reference Values in Healthy Participants for the Cardiac Troponin T High-Sensitivity Gen 6 Assay: REF-TSIX Global Reference Study
- Download full text (pdf) of Establishing Reference Values in Healthy Participants for the Cardiac Troponin T High-Sensitivity Gen 6 Assay: REF-TSIX Global Reference Study
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Part of CIRCULATION-POPULATION HEALTH AND OUTCOMES, 2026
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The plasma protein profile of left ventricular diastolic function
Part of Scientific Reports, 2026
- DOI for The plasma protein profile of left ventricular diastolic function
- Download full text (pdf) of The plasma protein profile of left ventricular diastolic function
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Predictors of depressed left-ventricular ejection fraction after acute myocardial infarction
Part of International Journal of Cardiology, 2026
- DOI for Predictors of depressed left-ventricular ejection fraction after acute myocardial infarction
- Download full text (pdf) of Predictors of depressed left-ventricular ejection fraction after acute myocardial infarction
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Exercise-induced cardiac troponin release: do we need to worry?
Part of European Heart Journal, p. 315-317, 2026
- DOI for Exercise-induced cardiac troponin release: do we need to worry?
- Download full text (pdf) of Exercise-induced cardiac troponin release: do we need to worry?
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Part of European Stroke Journal, 2026
- DOI for Early versus delayed DOAC after ischaemic stroke in atrial fibrillation: 1-year outcomes in the TIMING study and in concurrent practice
- Download full text (pdf) of Early versus delayed DOAC after ischaemic stroke in atrial fibrillation: 1-year outcomes in the TIMING study and in concurrent practice
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Part of European Heart Journal Open, 2026
- DOI for Cost-effectiveness analysis of transcatheter aortic valve implantation for asymptomatic severe aortic stenosis across nine European countries
- Download full text (pdf) of Cost-effectiveness analysis of transcatheter aortic valve implantation for asymptomatic severe aortic stenosis across nine European countries
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Part of Journal of Internal Medicine, p. 467-480, 2026
- DOI for The Swedish CArdioPulmonary bioImage Study re-examination: Rationale, design, methods, and management of incidental findings
- Download full text (pdf) of The Swedish CArdioPulmonary bioImage Study re-examination: Rationale, design, methods, and management of incidental findings
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Part of Journal of Hypertension, p. 346-353, 2026
- DOI for Systolic inter-arm blood pressure difference and subclinical atherosclerosis: a population-based cohort study of 29 921 individuals
- Download full text (pdf) of Systolic inter-arm blood pressure difference and subclinical atherosclerosis: a population-based cohort study of 29 921 individuals
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Part of CJC OPEN, p. 550-556, 2026
- DOI for Outcomes of No-Touch Vs Conventionally Harvested Saphenous Veins for Coronary Artery Bypass Surgery Individual Patient Data Meta-Analysis Protocol
- Download full text (pdf) of Outcomes of No-Touch Vs Conventionally Harvested Saphenous Veins for Coronary Artery Bypass Surgery Individual Patient Data Meta-Analysis Protocol
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Part of Cell Stem Cell, p. 1324-1338, 2026
- DOI for Extracellular vesicle secretome from mesenchymal stromal cells prevents post-ischemic heart failure by targeting cardiac fibrosis
- Download full text (pdf) of Extracellular vesicle secretome from mesenchymal stromal cells prevents post-ischemic heart failure by targeting cardiac fibrosis
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Part of ESC Heart Failure, 2026
- DOI for An integrated Biobank in the Swedish Heart Failure Registry-clinomics, proteomics, transcriptomics and genomics
- Download full text (pdf) of An integrated Biobank in the Swedish Heart Failure Registry-clinomics, proteomics, transcriptomics and genomics
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Dynamics of long-term adherence to lipid-lowering therapy in patients after myocardial infarction
Part of European Journal of Clinical Pharmacology, 2026
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Part of BMJ Open, 2026
- DOI for Diabetes status, fasting glucose and HbA1c, and outcomes after myocardial infarction: a retrospective registry-based Swedish cohort study
- Download full text (pdf) of Diabetes status, fasting glucose and HbA1c, and outcomes after myocardial infarction: a retrospective registry-based Swedish cohort study
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Part of Open heart, 2026
- DOI for Symptom burden and secondary prevention in patients with left ventricular systolic dysfunction after acute myocardial infarction: a nationwide register-based study in Sweden
- Download full text (pdf) of Symptom burden and secondary prevention in patients with left ventricular systolic dysfunction after acute myocardial infarction: a nationwide register-based study in Sweden
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Part of Open heart, 2026
- DOI for Physical fitness after myocardial infarction compared with clinical reference values: a SWEDEHEART registry study
- Download full text (pdf) of Physical fitness after myocardial infarction compared with clinical reference values: a SWEDEHEART registry study
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Part of HUMAN-ANIMAL INTERACTIONS, 2026
- DOI for Associations between dog and cat ownership, social integration, mental health and physical activity: A cross-sectional study from the SCAPIS population
- Download full text (pdf) of Associations between dog and cat ownership, social integration, mental health and physical activity: A cross-sectional study from the SCAPIS population
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Part of American Journal of Preventive Medicine, 2026
- DOI for Associations of adolescent BMI and physical fitness with cardiovascular health in middle age: a population-based prospective study of Swedish men
- Download full text (pdf) of Associations of adolescent BMI and physical fitness with cardiovascular health in middle age: a population-based prospective study of Swedish men
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Part of Journal of Thrombosis and Haemostasis, p. 399-407, 2026
- DOI for Evaluation of the updated ABC-AF-bleeding score 2.0 in patients with atrial fibrillation treated with a direct oral anticoagulant or warfarin
- Download full text (pdf) of Evaluation of the updated ABC-AF-bleeding score 2.0 in patients with atrial fibrillation treated with a direct oral anticoagulant or warfarin
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Part of European Heart Journal, p. 3951-3961, 2026
- DOI for Outcomes after a first acute myocardial infarction in patients with or without congenital heart disease
- Download full text (pdf) of Outcomes after a first acute myocardial infarction in patients with or without congenital heart disease
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How to Make Medical Device Registry Data Fit for Purpose: A Response to Recent Commentaries
Part of International Journal of Health Policy and Management, 2026
- DOI for How to Make Medical Device Registry Data Fit for Purpose: A Response to Recent Commentaries
- Download full text (pdf) of How to Make Medical Device Registry Data Fit for Purpose: A Response to Recent Commentaries
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Realizing the full potential of registry-based randomized controlled trials
Part of Journal of Clinical Epidemiology, 2026
- DOI for Realizing the full potential of registry-based randomized controlled trials
- Download full text (pdf) of Realizing the full potential of registry-based randomized controlled trials
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Molecular mechanisms of coronary microembolization-induced MINOCA
Part of Basic Research in Cardiology, p. 605-628, 2026
- DOI for Molecular mechanisms of coronary microembolization-induced MINOCA
- Download full text (pdf) of Molecular mechanisms of coronary microembolization-induced MINOCA
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Part of Journal of Nuclear Cardiology, 2026
- DOI for Evaluation of Gd-DOTA as a marker for myocardial blood flow using 68Ga-DOTA and 15O-water positron emission tomography
- Download full text (pdf) of Evaluation of Gd-DOTA as a marker for myocardial blood flow using 68Ga-DOTA and 15O-water positron emission tomography
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Part of Ultraschall in der Medizin, p. 149-159, 2026
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Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome
Part of Cell, p. 3339-+, 2026
- DOI for Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome
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Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction
Part of New England Journal of Medicine, p. 540-550, 2026
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Part of Journal of Investigative Dermatology, 2026
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Part of Heart, p. 761-770, 2026
- DOI for Risk and protective factors for stroke and transient ischaemic attack in patients with atrial fibrillation: an umbrella review of meta-analyses
- Download full text (pdf) of Risk and protective factors for stroke and transient ischaemic attack in patients with atrial fibrillation: an umbrella review of meta-analyses
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Part of Journal of the American Heart Association, 2026
- DOI for Randomized Controlled Trial of Internet-Delivered Cognitive Behavioral Therapy After Myocardial Infarction With Nonobstructive Coronary Arteries or Takotsubo Syndrome
- Download full text (pdf) of Randomized Controlled Trial of Internet-Delivered Cognitive Behavioral Therapy After Myocardial Infarction With Nonobstructive Coronary Arteries or Takotsubo Syndrome
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Part of Scientific Reports, 2026
- DOI for Growth differentiation factor-15 improves long-term mortality risk prediction beyond the GRACE 2.0 score after acute coronary syndrome
- Download full text (pdf) of Growth differentiation factor-15 improves long-term mortality risk prediction beyond the GRACE 2.0 score after acute coronary syndrome
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Part of European Journal of Radiology, 2026
- DOI for Improved coronary CT angiography image quality using photon-counting detector CT in SCAPIS reexamination: scan protocol and comparative analysis
- Download full text (pdf) of Improved coronary CT angiography image quality using photon-counting detector CT in SCAPIS reexamination: scan protocol and comparative analysis
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Part of American Heart Journal Plus: Cardiology Research and Practice, 2026
- DOI for Health related quality of life and cardiac symptoms following admission for suspected MINOCA: A post-hoc analysis of the MINOCA-BAT randomized clinical trial
- Download full text (pdf) of Health related quality of life and cardiac symptoms following admission for suspected MINOCA: A post-hoc analysis of the MINOCA-BAT randomized clinical trial
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Part of Clinical Biochemistry, 2026
- DOI for Change in cardiac troponin T to differentiate acute from chronic myocardial injury in the Emergency Department
- Download full text (pdf) of Change in cardiac troponin T to differentiate acute from chronic myocardial injury in the Emergency Department
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Cardiomyopathies: Nationwide Trends in Prevalence, Incidence, and Mortality (2004-2023)
Part of Journal of the American College of Cardiology, p. 1087-1090, 2026