Madlen Hubert

Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Ingår i Journal of Colloid and Interface Science, s. 287-300, 2025

• DOI för Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
• Ladda ner fulltext (pdf) av Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

Antimicrobial Peptides Incorporating Halogenated Marine-Derived Amino Acid Substituents

Craig, Alexander J.; Ermolovich, Yuri; Cameron, Alan; Rodler, Agnes et al.

Ingår i ACS Medicinal Chemistry Letters, s. 802-809, 2023

• DOI för Antimicrobial Peptides Incorporating Halogenated Marine-Derived Amino Acid Substituents

Membrane insertion mechanism of the caveola coat protein Cavin1

Liu, Kang-Cheng; Pace, Hudson; Larsson, Elin; Hossain, Md Shakhawath et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2022

• DOI för Membrane insertion mechanism of the caveola coat protein Cavin1
• Ladda ner fulltext (pdf) av Membrane insertion mechanism of the caveola coat protein Cavin1

Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters

Palica, Katarzyna; Vorácová, Manuela; Skagseth, Susann; Andersson Rasmussen, Anna et al.

Ingår i ACS Omega, s. 4550-4562, 2022

• DOI för Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters
• Ladda ner fulltext (pdf) av Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters

NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor

Wieske, Lianne H. E.; Bogaerts, Jonathan; Leding, Albin A. M.; Wilcox, Scott et al.

Ingår i ACS Medicinal Chemistry Letters, s. 257-261, 2022

• DOI för NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor
• Ladda ner fulltext (pdf) av NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor

Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Ingår i Journal of Colloid and Interface Science, s. 287-300, 2025

• DOI för Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
• Ladda ner fulltext (pdf) av Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

Antimicrobial Peptides Incorporating Halogenated Marine-Derived Amino Acid Substituents

Craig, Alexander J.; Ermolovich, Yuri; Cameron, Alan; Rodler, Agnes et al.

Ingår i ACS Medicinal Chemistry Letters, s. 802-809, 2023

• DOI för Antimicrobial Peptides Incorporating Halogenated Marine-Derived Amino Acid Substituents

Membrane insertion mechanism of the caveola coat protein Cavin1

Liu, Kang-Cheng; Pace, Hudson; Larsson, Elin; Hossain, Md Shakhawath et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2022

• DOI för Membrane insertion mechanism of the caveola coat protein Cavin1
• Ladda ner fulltext (pdf) av Membrane insertion mechanism of the caveola coat protein Cavin1

Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters

Palica, Katarzyna; Vorácová, Manuela; Skagseth, Susann; Andersson Rasmussen, Anna et al.

Ingår i ACS Omega, s. 4550-4562, 2022

• DOI för Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters
• Ladda ner fulltext (pdf) av Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters

NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor

Wieske, Lianne H. E.; Bogaerts, Jonathan; Leding, Albin A. M.; Wilcox, Scott et al.

Ingår i ACS Medicinal Chemistry Letters, s. 257-261, 2022

• DOI för NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor
• Ladda ner fulltext (pdf) av NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor

PIP5K1 alpha is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer

Wang, Tianyan; Sarwar, Martuza; Whitchurch, Jonathan B.; Collins, Hilary M. et al.

Ingår i Frontiers in Cell and Developmental Biology, 2022

• DOI för PIP5K1 alpha is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer
• Ladda ner fulltext (pdf) av PIP5K1 alpha is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer

Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay

Keemink, Janneke; Hedge, Oliver; Bianco, Valentina; Hubert, Madlen et al.

Ingår i Journal of Pharmaceutical Sciences, s. 175-184, 2022

• DOI för Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay
• Ladda ner fulltext (pdf) av Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay

A comparison of chitosan, mesoporous silica and poly(lactic-co-glycolic) acid nanocarriers for optimising intestinal uptake of oral protein therapeutics

Wright, Leah; Joyce, Paul; Barnes, Timothy J.; Lundmark, Richard et al.

Ingår i Journal of Pharmaceutical Sciences, s. 217-227, 2021

• DOI för A comparison of chitosan, mesoporous silica and poly(lactic-co-glycolic) acid nanocarriers for optimising intestinal uptake of oral protein therapeutics

Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation

Kabedev, Aleksei; Hossain, Shakhawath; Hubert, Madlen; Larsson, Per et al.

Ingår i Journal of Pharmaceutical Sciences, s. 176-185, 2021

• DOI för Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation
• Ladda ner fulltext (pdf) av Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation

3D-printing of solid lipid tablets from emulsion gels

Johannesson, Jenny; Khan, Jamal; Hubert, Madlen; Teleki, Alexandra et al.

Ingår i International Journal of Pharmaceutics, 2021

• DOI för 3D-printing of solid lipid tablets from emulsion gels
• Ladda ner fulltext (pdf) av 3D-printing of solid lipid tablets from emulsion gels

Analysis of Protein and Lipid Interactions Using Liposome Co-sedimentation Assays.

Larsson, Elin; Hubert, Madlen; Lundmark, Richard

Ingår i Methods in Molecular Biology, s. 119-127, 2020

• DOI för Analysis of Protein and Lipid Interactions Using Liposome Co-sedimentation Assays.

Lipid accumulation controls the balance between surface connection and scission of caveolae.

Hubert, Madlen; Larsson, Elin; Vegesna, Naga Venkata Gayathri; Ahnlund, Maria et al.

Ingår i eLIFE, 2020

• DOI för Lipid accumulation controls the balance between surface connection and scission of caveolae.

Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries

Rodrigues, Leticia; Schneider, Fabian; Zhang, Xiaohan; Larsson, Elin et al.

Ingår i Journal of Colloid and Interface Science, s. 820-833, 2019

• DOI för Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries

Photoactivated Colibactin Probes Induce Cellular DNA Damage.

Moodie, Lindon W K; Hubert, Madlen; Zhou, Xin; Albers, Michael F et al.

Ingår i Angewandte Chemie International Edition, s. 1417-1421, 2019

• DOI för Photoactivated Colibactin Probes Induce Cellular DNA Damage.

Progress in formulation development and sterilisation of freeze-dried oligodeoxynucleotide-loaded gelatine nanoparticles.

Geh, Katharina J; Hubert, Madlen; Winter, Gerhard

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 10-20, 2018

• DOI för Progress in formulation development and sterilisation of freeze-dried oligodeoxynucleotide-loaded gelatine nanoparticles.

Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein.

Rodrigues, Letícia; Raftopoulos, Konstantinos N; Tandrup Schmidt, Signe; Schneider, Fabian et al.

Ingår i Journal of Controlled Release, s. 12-22, 2018

• DOI för Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein.

Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion.

Holst, Mikkel Roland; Vidal-Quadras, Maite; Larsson, Elin; Song, Jie et al.

Ingår i Cell Reports, s. 1893-1905, 2017

• DOI för Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion.

Preliminary evaluation of cytosine-phosphate-guanine oligodeoxynucleotides bound to gelatine nanoparticles as immunotherapy for canine atopic dermatitis.

Wagner, I; Geh, K J; Hubert, M; Winter, G et al.

Ingår i The Veterinary Record, 2017

• DOI för Preliminary evaluation of cytosine-phosphate-guanine oligodeoxynucleotides bound to gelatine nanoparticles as immunotherapy for canine atopic dermatitis.

Characterization of Lipid-Based Hexosomes as Versatile Vaccine Carriers.

Rodrigues, Letícia; Kyriakos, Konstantinos; Schneider, Fabian; Dietz, Hendrik et al.

Ingår i Molecular Pharmaceutics, s. 3945-3954, 2016

• DOI för Characterization of Lipid-Based Hexosomes as Versatile Vaccine Carriers.

Optimisation of one-step desolvation and scale-up of gelatine nanoparticle production.

Geh, Katharina J; Hubert, Madlen; Winter, Gerhard

Ingår i Journal of Microencapsulation, s. 595-604, 2016

• DOI för Optimisation of one-step desolvation and scale-up of gelatine nanoparticle production.

Physical characterization of synthetic phosphatidylinositol dimannosides and analogues in binary systems with phosphatidylcholine.

Hubert, Madlen; Larsen, David S; Hayman, Colin M; Rades, Thomas et al.

Ingår i Molecular Pharmaceutics, s. 913-21, 2014

• DOI för Physical characterization of synthetic phosphatidylinositol dimannosides and analogues in binary systems with phosphatidylcholine.

Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues.

Hubert, Madlen; Compton, Benjamin J; Hayman, Colin M; Larsen, David S et al.

Ingår i Molecular Pharmaceutics, s. 1928-39, 2013

• DOI för Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues.

Formation Kinetics and Stability of Carbamazepine−Nicotinamide Cocrystals Prepared by Mechanical Activation

Chieng, Norman; Hubert, Madlen; Saville, Dorothy; Rades, Thomas et al.

Ingår i Crystal Growth & Design, s. 2377-2386, 2009

• DOI för Formation Kinetics and Stability of Carbamazepine−Nicotinamide Cocrystals Prepared by Mechanical Activation

Keeping in touch with the membrane: protein- and lipid-mediated confinement of caveolae to the cell surface

Hubert, Madlen; Larsson, Elin; Lundmark, Richard

Ingår i Biochemical Society Transactions, s. 155-163, 2020

• DOI för Keeping in touch with the membrane: protein- and lipid-mediated confinement of caveolae to the cell surface
• Ladda ner fulltext (pdf) av Keeping in touch with the membrane: protein- and lipid-mediated confinement of caveolae to the cell surface