Moritz Senger
Forskare vid Institutionen för kemi inom livsvetenskaperna; Biokemi; Senger Grupp
- E-post:
- moritz.senger@kemi.uu.se
- Besöksadress:
- Husargatan 3
752 37 Uppsala - Postadress:
- Box 576
75123 Uppsala
- CV:
- Ladda ned CV
- ORCID:
- 0000-0001-9225-4910
Kort presentation
Enzymatic catalysis investigated by time-resolved spectroscopy and crystallography for sustainable energy solutions
Google Scholar: scholar.google.com/citations?hl=en&user=WQkHnkMAAAAJ
ORCID iD: orcid.org/0000-0001-9225-4910
Linkedin: https://www.linkedin.com/in/moritz-senger-0859a42b1/
Bluesky: @moritzsenger.bsky.social
Twitter: twitter.com/MoritzSenger
Research Gate: researchgate.net/profile/Moritz_Senger
Nyckelord
- catalysis
- photocatalysis
- hydrogenase
- nitrogenase
- time resolved spectroscopy and structure determination
- infrared spectroscopy
Biografi
2026 Docent in Biochemistry
Biochemistry, Department of Chemistry for Life Sciences, Uppsala Universitet, Sweden
2024 Principal Investigator
Biochemistry, Department of Chemistry, Bio Medical Centre (BMC), Uppsala Universitet, Sweden
2022 – 2024 Postdoctoral Researcher
Biophysical and Bioinorganic Chemistry, Molecular Biomimetics (Prof. Berggren), Department of Chemistry, Ångström Laboratory, Uppsala Universitet, Sweden
2020 –2022 Postdoctoral Researcher
Physical Chemistry (Prof. Hammarström), Department of Chemistry, Ångström, Uppsala Universitet, Sweden
2018 – 2019 Postdoctoral Researcher
Molecular Biophysics, Department of Physics, Freie Universität Berlin, Germany
2018 PhD in Physics
Molecular Biophysics (Prof. Heberle), Department of Physics, Freie Universität Berlin, Germany
Forskning
Time-resolved spectroscopy and structure determination of [FeFe]-hydrogenases and nitrogenases inspiring green hydrogen and sustainable fertilizer production
Media
https://blogs.rsc.org/cc/2024/09/13/chemcomm-milestones-moritz-senger/
Publikationer
Urval av publikationer
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Ingår i Physical Chemistry, Chemical Physics - PCCP, s. 9864-9875, 2025
- DOI för Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
- Ladda ner fulltext (pdf) av Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
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Minimal and hybrid hydrogenases are active from archaea
Ingår i Cell, 2024
- DOI för Minimal and hybrid hydrogenases are active from archaea
- Ladda ner fulltext (pdf) av Minimal and hybrid hydrogenases are active from archaea
-
Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
Ingår i Chemical Communications, s. 10914-10917, 2024
- DOI för Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
- Ladda ner fulltext (pdf) av Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
-
Ingår i ACS Catalysis, s. 10435-10446, 2023
- DOI för Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
- Ladda ner fulltext (pdf) av Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
-
Structural basis for bacterial energy extraction from atmospheric hydrogen
Ingår i Nature, s. 541-547, 2023
- DOI för Structural basis for bacterial energy extraction from atmospheric hydrogen
- Ladda ner fulltext (pdf) av Structural basis for bacterial energy extraction from atmospheric hydrogen
-
Ingår i ACS Sustainable Chemistry and Engineering, s. 10760-10767, 2022
- DOI för Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
- Ladda ner fulltext (pdf) av Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
-
Ingår i Chemical Communications, s. 7184-7187, 2022
- DOI för Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
- Ladda ner fulltext (pdf) av Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
Senaste publikationer
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2026
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Ingår i Analytical Chemistry, s. 26393-26403, 2025
- DOI för Reconsidering the Enzyme Kinetics of [FeFe]-Hydrogenases: Improved Turnover Rates and New Insights into pH and Potential Dependence with Eu(II)-Based Solution Assays
- Ladda ner fulltext (pdf) av Reconsidering the Enzyme Kinetics of [FeFe]-Hydrogenases: Improved Turnover Rates and New Insights into pH and Potential Dependence with Eu(II)-Based Solution Assays
-
Ingår i Physical Chemistry, Chemical Physics - PCCP, s. 9864-9875, 2025
- DOI för Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
- Ladda ner fulltext (pdf) av Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
-
Ingår i Journal of the American Chemical Society, s. 4654-4666, 2025
- DOI för Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase
- Ladda ner fulltext (pdf) av Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase
-
Minimal and hybrid hydrogenases are active from archaea
Ingår i Cell, 2024
- DOI för Minimal and hybrid hydrogenases are active from archaea
- Ladda ner fulltext (pdf) av Minimal and hybrid hydrogenases are active from archaea
Alla publikationer
Artiklar i tidskrift
-
Ingår i Analytical Chemistry, s. 26393-26403, 2025
- DOI för Reconsidering the Enzyme Kinetics of [FeFe]-Hydrogenases: Improved Turnover Rates and New Insights into pH and Potential Dependence with Eu(II)-Based Solution Assays
- Ladda ner fulltext (pdf) av Reconsidering the Enzyme Kinetics of [FeFe]-Hydrogenases: Improved Turnover Rates and New Insights into pH and Potential Dependence with Eu(II)-Based Solution Assays
-
Ingår i Physical Chemistry, Chemical Physics - PCCP, s. 9864-9875, 2025
- DOI för Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
- Ladda ner fulltext (pdf) av Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
-
Ingår i Journal of the American Chemical Society, s. 4654-4666, 2025
- DOI för Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase
- Ladda ner fulltext (pdf) av Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase
-
Minimal and hybrid hydrogenases are active from archaea
Ingår i Cell, 2024
- DOI för Minimal and hybrid hydrogenases are active from archaea
- Ladda ner fulltext (pdf) av Minimal and hybrid hydrogenases are active from archaea
-
Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
Ingår i Chemical Communications, s. 10914-10917, 2024
- DOI för Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
- Ladda ner fulltext (pdf) av Secondary structure changes as the potential H2 sensing mechanism of group D [FeFe]-hydrogenases
-
Ingår i ACS Catalysis, s. 9476-9486, 2023
- DOI för Elucidating Electron Transfer Kinetics and Optimizing System Performance for Escherichia coli-Based Semi-Artificial H-2 Production
- Ladda ner fulltext (pdf) av Elucidating Electron Transfer Kinetics and Optimizing System Performance for Escherichia coli-Based Semi-Artificial H-2 Production
-
Ingår i ACS Catalysis, s. 10435-10446, 2023
- DOI för Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
- Ladda ner fulltext (pdf) av Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
-
Structural basis for bacterial energy extraction from atmospheric hydrogen
Ingår i Nature, s. 541-547, 2023
- DOI för Structural basis for bacterial energy extraction from atmospheric hydrogen
- Ladda ner fulltext (pdf) av Structural basis for bacterial energy extraction from atmospheric hydrogen
-
Ingår i ACS Sustainable Chemistry and Engineering, s. 10760-10767, 2022
- DOI för Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
- Ladda ner fulltext (pdf) av Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
-
Ingår i Chemical Science, s. 11058-11064, 2022
- DOI för Investigating the role of the strong field ligands in [FeFe] hydrogenase: spectroscopic and functional characterization of a semi-synthetic mono-cyanide active site
- Ladda ner fulltext (pdf) av Investigating the role of the strong field ligands in [FeFe] hydrogenase: spectroscopic and functional characterization of a semi-synthetic mono-cyanide active site
-
Ingår i Chemical Communications, s. 7184-7187, 2022
- DOI för Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
- Ladda ner fulltext (pdf) av Hydride state accumulation in native [FeFe]-hydrogenase with the physiological reductant H-2 supports its catalytic relevance
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Ingår i Inorganic Chemistry, s. 10036-10042, 2022
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Ingår i Journal of the American Chemical Society, s. 13600-13611, 2022
- DOI för Polymer Dots as Photoactive Membrane Vesicles for [FeFe]-Hydrogenase Self-Assembly and Solar-Driven Hydrogen Evolution
- Ladda ner fulltext (pdf) av Polymer Dots as Photoactive Membrane Vesicles for [FeFe]-Hydrogenase Self-Assembly and Solar-Driven Hydrogen Evolution
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Ingår i Physiologia Plantarum, s. 555-567, 2021
- DOI för Photosynthetic hydrogen production: Novel protocols, promising engineering approaches and application of semi‐synthetic hydrogenases
- Ladda ner fulltext (pdf) av Photosynthetic hydrogen production: Novel protocols, promising engineering approaches and application of semi‐synthetic hydrogenases
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Site-selective protonation of the one-electron reduced cofactor in [FeFe]-hydrogenase
Ingår i Dalton Transactions, s. 3641-3650, 2021
- DOI för Site-selective protonation of the one-electron reduced cofactor in [FeFe]-hydrogenase
- Ladda ner fulltext (pdf) av Site-selective protonation of the one-electron reduced cofactor in [FeFe]-hydrogenase
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Ingår i Journal of Biological Inorganic Chemistry, s. 777-788, 2020
- DOI för [FeFe]-hydrogenase maturation: H-cluster assembly intermediates tracked by electron paramagnetic resonance, infrared, and X-ray absorption spectroscopy
- Ladda ner fulltext (pdf) av [FeFe]-hydrogenase maturation: H-cluster assembly intermediates tracked by electron paramagnetic resonance, infrared, and X-ray absorption spectroscopy
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Ingår i Chemical Science, s. 12789-12801, 2020
- DOI för Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture
- Ladda ner fulltext (pdf) av Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture
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Current State of [FeFe]-Hydrogenase Research: Biodiversity and Spectroscopic Investigations
Ingår i ACS Catalysis, s. 7069-7086, 2020