Olof Idevall

Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Mendes Rodrigues Junior, Dorival; Saez-Ibañez, Ana Rosa; Terabayashi, Takeshi; Daubel, Nina et al.

Ingår i Journal of Cell Biology, 2025

• DOI för Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles
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Somatostatin triggers local cAMP and Ca²⁺ signaling in primary cilia to modulate pancreatic β-cell function

Incedal Nilsson, Ceren; Dumral, Özge; Sanchez, Gonzalo; Xie, Beichen et al.

Ingår i EMBO Journal, s. 1663-1691, 2025

• DOI för Somatostatin triggers local cAMP and Ca²⁺ signaling in primary cilia to modulate pancreatic β-cell function
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OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion

Panagiotou, Styliani; Tan, Kia Wee; Nguyen, Phuoc My; Mueller, Andreas et al.

Ingår i Cell Reports, 2024

• DOI för OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion
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“Blue Light, Camera, Action!”

O'Callaghan, Paul; Idevall Hagren, Olof

Ingår i ACS Central Science, s. 514-516, 2024

• DOI för “Blue Light, Camera, Action!”

Complex regulation of mitochondrial signaling by human adenovirus minor capsid protein VI

Schubert, Erik; Mun, Kwangchol; Larsson, Mårten; Panagiotou, Styliani et al.

Ingår i Journal of Virology, 2024

• DOI för Complex regulation of mitochondrial signaling by human adenovirus minor capsid protein VI

Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Mendes Rodrigues Junior, Dorival; Saez-Ibañez, Ana Rosa; Terabayashi, Takeshi; Daubel, Nina et al.

Ingår i Journal of Cell Biology, 2025

• DOI för Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles
• Ladda ner fulltext (pdf) av Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Somatostatin triggers local cAMP and Ca²⁺ signaling in primary cilia to modulate pancreatic β-cell function

Incedal Nilsson, Ceren; Dumral, Özge; Sanchez, Gonzalo; Xie, Beichen et al.

Ingår i EMBO Journal, s. 1663-1691, 2025

• DOI för Somatostatin triggers local cAMP and Ca²⁺ signaling in primary cilia to modulate pancreatic β-cell function
• Ladda ner fulltext (pdf) av Somatostatin triggers local cAMP and Ca²⁺ signaling in primary cilia to modulate pancreatic β-cell function

OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion

Panagiotou, Styliani; Tan, Kia Wee; Nguyen, Phuoc My; Mueller, Andreas et al.

Ingår i Cell Reports, 2024

• DOI för OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion
• Ladda ner fulltext (pdf) av OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion

“Blue Light, Camera, Action!”

O'Callaghan, Paul; Idevall Hagren, Olof

Ingår i ACS Central Science, s. 514-516, 2024

• DOI för “Blue Light, Camera, Action!”

Complex regulation of mitochondrial signaling by human adenovirus minor capsid protein VI

Schubert, Erik; Mun, Kwangchol; Larsson, Mårten; Panagiotou, Styliani et al.

Ingår i Journal of Virology, 2024

• DOI för Complex regulation of mitochondrial signaling by human adenovirus minor capsid protein VI

The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling

Sanchez, Gonzalo; Incedal, Tugce Ceren; Prada, Juan; O'Callaghan, Paul et al.

Ingår i Journal of Cell Biology, 2023

• DOI för The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling
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Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells

Yang, Mingyu; Dyachok, Oleg; Xu, Yunjian; Gylfe, Erik et al.

Ingår i Cellular Signalling, 2023

• DOI för Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells
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Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine

Ngamjariyawat, Anongnad; Cen, Jing; Said, Romain; Incedal, Ceren et al.

Ingår i Frontiers in Endocrinology, 2023

• DOI för Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine
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Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells

O'Callaghan, Paul; Engberg, Adam; Eriksson, Olle; Fatsis-Kavalopoulos, Nikos et al.

Ingår i Journal of Cell Science, 2022

• DOI för Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells
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The endoplasmic reticulum-plasma membrane tethering protein TMEM24 is a regulator of cellular Ca2+ homeostasis

Xie, Beichen; Panagiotou, Styliani; Cen, Jing; Gilon, Patrick et al.

Ingår i Journal of Cell Science, 2022

• DOI för The endoplasmic reticulum-plasma membrane tethering protein TMEM24 is a regulator of cellular Ca2+ homeostasis
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Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

Mousavy Gharavy, S. Neda; Owen, Bryn M.; Millership, Steven J.; Chabosseau, Pauline et al.

Ingår i Diabetologia, s. 850-864, 2021

• DOI för Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis
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Dual Function of PI(4,5)P₂ in Insulin-Regulated Exocytic Trafficking of GLUT4 in Adipocytes

Li, Hanbing; Shentu, Ping; Xiao, Mei; Zhao, Xuqin et al.

Ingår i Journal of Molecular Biology, s. 4341-4357, 2020

• DOI för Dual Function of PI(4,5)P₂ in Insulin-Regulated Exocytic Trafficking of GLUT4 in Adipocytes

The PI(4)P phosphatase Sac2 controls insulin granule docking and release

Nguyen, Phuoc My; Gandasi, Nikhil; Xie, Beichen; Sugahara, Sari et al.

Ingår i Journal of Cell Biology, s. 3714-3729, 2019

• DOI för The PI(4)P phosphatase Sac2 controls insulin granule docking and release
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Feedback regulation of insulin secretion by extended synaptotagmin-1

Xie, Beichen; Nguyen, Phuoc My; Idevall-Hagren, Olof

Ingår i The FASEB Journal, s. 4716-4728, 2019

• DOI för Feedback regulation of insulin secretion by extended synaptotagmin-1

Cortical mitochondria regulate insulin secretion by local Ca2+ buffering in rodent beta cells

Griesche, Nadine; Sanchez, Gonzalo; Hermans, Cedric; Idevall Hagren, Olof

Ingår i Journal of Cell Science, 2019

• DOI för Cortical mitochondria regulate insulin secretion by local Ca2+ buffering in rodent beta cells

Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution

Fatsis-Kavalopoulos, Nikos; O'Callaghan, Paul; Xie, Beichen; Hernández Vera, Rodrigo et al.

Ingår i Lab on a Chip, s. 1071-1081, 2019

• DOI för Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution
• Ladda ner fulltext (pdf) av Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution

Development of a Wireless-Controlled LED Array for the Tunable Optogenetic Control of Cellular Activities

Qi, Yuankai; Chen, Junye; Liu, Xuechun; Zhou, Xiaoxu et al.

Ingår i ENGINEERING, s. 745-747, 2018

• DOI för Development of a Wireless-Controlled LED Array for the Tunable Optogenetic Control of Cellular Activities
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The lipid phosphatase INPP5F regulates insulin secretion

Nguyen, Phuoc My; Gandasi, Nikhil R; Idevall-Hagren, Olof

Ingår i Diabetologia, 2018

A genetically encoded low-affinity Ca2+ sensor unmasks autocrine purinergic signalling in beta cells

Yang, Mingyu; Idevall-Hagren, Olof; Gylfe, Erik; Tengholm, Anders

Ingår i Diabetologia, 2018

Extended synaptotagmin-1 controls insulin secretion through diacylglycerol transport at ER-PM contact sites

Xie, Beichen; Idevall-Hagren, Olof

Ingår i Diabetologia, 2018

Plasma Membrane Phosphatidylinositol 4,5-Bisphosphate Regulates Ca2+-Influx and Insulin Secretion from Pancreatic beta Cells

Xie, Beichen; Nguyen, Phuoc My; Gucek, Alenka; Thonig, Antje et al.

Ingår i CELL CHEMICAL BIOLOGY, s. 816-826, 2016

• DOI för Plasma Membrane Phosphatidylinositol 4,5-Bisphosphate Regulates Ca2+-Influx and Insulin Secretion from Pancreatic beta Cells

Plasma membrane PI(4,5)P-2 is required for normal glucose-stimulated insulin secretion

Xie, Beichen; Nguyen, Phuoc My; Thonig, Antje; Idevall-Hagren, Olof

Ingår i Diabetologia, 2016

Plasma membrane PI(4,5)P-2 controls Ca2+-influx in clonal beta cells

Nguyen, Phuoc My; Xie, Beichen; Idevall-Hagren, Olof

Ingår i Diabetologia, 2016

Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering

Idevall Hagren, Olof; Lue, Alice; Xie, Beichen; De Camilli, Pietro

Ingår i EMBO Journal, s. 2291-2305, 2015

• DOI för Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering

Optogenetic Manipulation of Phosphoinositides

Idevall-Hagren, Olof

Ingår i The FASEB Journal, 2015

Ca2+-dependent expansion of cortical ER in insulin-secreting beta cells

Xie, Beichen; Idevall-Hagren, Olof

Ingår i Diabetologia, 2015

Spatial Control of Epac2 Activity by cAMP and Ca2+-Mediated Activation of Ras in Pancreatic beta Cells

Idevall-Hagren, Olof; Jakobsson, Ida; Xu, Yunjian; Tengholm, Anders

Ingår i Science Signaling, 2013

• DOI för Spatial Control of Epac2 Activity by cAMP and Ca2+-Mediated Activation of Ras in Pancreatic beta Cells

P2Y₁ receptor-dependent diacylglycerol signaling microdomains in β cells promote insulin secretion

Wuttke, Anne; Idevall-Hagren, Olof; Tengholm, Anders

Ingår i The FASEB Journal, s. 1610-1620, 2013

• DOI för P2Y₁ receptor-dependent diacylglycerol signaling microdomains in β cells promote insulin secretion

Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5'-phosphatase interaction with c-Abl

Mokhtari, Dariush; Al-Amin, Abdullah; Turpaev, Kyrill; Li, Tingting et al.

Ingår i Diabetologia, s. 1327-1338, 2013

• DOI för Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5'-phosphatase interaction with c-Abl
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cAMP Mediators of Pulsatile Insulin Secretion from Glucose-stimulated Single β-Cells

Idevall Hagren, Olof; Barg, Sebastian; Gylfe, Erik; Tengholm, Anders

Ingår i Journal of Biological Chemistry, s. 23005-23016, 2010

• DOI för cAMP Mediators of Pulsatile Insulin Secretion from Glucose-stimulated Single β-Cells

Tensin2 reduces intracellular phosphatidylinositol 3,4,5-trisphosphate levels at the plasma membrane

Hafizi, Sassan; Gustafsson, Anna; Oslakovic, Cecilia; Idevall-Hagren, Olof et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 396-401, 2010

• DOI för Tensin2 reduces intracellular phosphatidylinositol 3,4,5-trisphosphate levels at the plasma membrane

PI3-kinase p110 alpha mediates beta 1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading

Zeller, Kathrin S.; Idevall Hagren, Olof; Stefansson, Anne; Velling, Teet et al.

Ingår i Cellular Signalling, s. 1838-1848, 2010

• DOI för PI3-kinase p110 alpha mediates beta 1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading

Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion

Dyachok, Oleg; Idevall-Hagren, Olof; Sågetorp, Jenny; Tian, Geng et al.

Ingår i Cell Metabolism, s. 26-37, 2008

• DOI för Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
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Keeping pace: the primary cilium as the conducting baton of the islet

Idevall Hagren, Olof; Incedal Nilsson, Ceren; Sanchez, Gonzalo

Ingår i Diabetologia, s. 773-782, 2024

• DOI för Keeping pace: the primary cilium as the conducting baton of the islet
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Insulin granule biogenesis and exocytosis

Omar-Hmeadi, Muhmmad; Idevall Hagren, Olof

Ingår i Cellular and Molecular Life Sciences (CMLS), s. 1957-1970, 2021

• DOI för Insulin granule biogenesis and exocytosis
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Metabolic regulation of calcium signaling in beta cells

Idevall Hagren, Olof; Tengholm, Anders

Ingår i Seminars in Cell and Developmental Biology, s. 20-30, 2020

• DOI för Metabolic regulation of calcium signaling in beta cells

Detection and manipulation of phosphoinositides

Idevall-Hagren, Olof; De Camilli, Pietro

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 736-745, 2015

• DOI för Detection and manipulation of phosphoinositides

Spatio-Temporal Dynamics of Phosphatidylinositol-3,4,5-Trisphosphate Signalling

Tengholm, Anders; Idevall-Hagren, Olof

Ingår i Vitamines and Hormones, s. 287-311, 2009

• DOI för Spatio-Temporal Dynamics of Phosphatidylinositol-3,4,5-Trisphosphate Signalling

Oscillatory Signaling and Insulin Secretion from Single ß-cells

Idevall Hagren, Olof

2010

• Ladda ner fulltext (pdf) av Oscillatory Signaling and Insulin Secretion from Single ß-cells

Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging

Dyachok, Oleg; Xu, Yunjian; Idevall, Olof; Tengholm, Anders

Ingår i cAMP Signaling, s. 319-338, Humana Press, 2022

• DOI för Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging

Imaging sub-plasma membrane cAMP dynamics with fluorescent translocation reporters

Tengholm, Anders; Idevall-Hagren, Olof

Ingår i cAMP Signaling, s. 85-101, Springer-Verlag New York, 2015

• DOI för Imaging sub-plasma membrane cAMP dynamics with fluorescent translocation reporters
• Ladda ner fulltext (pdf) av Imaging sub-plasma membrane cAMP dynamics with fluorescent translocation reporters

Imaging phosphoinositide dynamics in living cells

Wuttke, Anne; Idevall-Hagren, Olof; Tengholm, Anders

Ingår i Inositol Phosphates and Lipids, s. 219-235, Humana Press, 2010

• DOI för Imaging phosphoinositide dynamics in living cells
• Ladda ner fulltext (pdf) av Imaging phosphoinositide dynamics in living cells

Exocytotic release of ATP triggers diacylglycerol spiking in insulin-secreting cells

Wuttke, Anne; Idevall-Hagren, Olof; Tengholm, Anders

Ingår i Minutes Of The 46th General Assembly Of The European Association For The Study Of Diabetes, 2011

• DOI för Exocytotic release of ATP triggers diacylglycerol spiking in insulin-secreting cells

cGMP signaling in the primary cilium of islet cells

Incedal Nilsson, Ceren; Dumral, Özge; Idevall-Hagren, Olof