Andreas Hellander
Universitetslektor vid Institutionen för informationsteknologi; Beräkningsvetenskap
- Telefon:
- 018-471 29 72
- Mobiltelefon:
- 070-395 04 47, 073-469 70 10
- E-post:
- andreas.hellander@it.uu.se
- Besöksadress:
- Hus 10, Regementsvägen 10
- Postadress:
- Box 524
751 20 UPPSALA
- Akademiska meriter:
- Docent
Nyckelord
- computational systems biology
- applied cloud computing
- escience
- computational science and engineering
Forskning
With a core in scientific computing and systems biology, the work in the lab aims to develop next-generation tools for smart and efficient computational experimentation. A prominent application area is systems biology, where we use simulations to study spatial and temporal aspects of cellular regulatory systems. To that effect, we pursue a broad range of topics ranging from development of multiscale methods for spatial stochastic simulations to modelling of multicellular systems to cloud computing and development of smart and interactive computational science and engineering software.

Publikationer
Senaste publikationer
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Accelerating Simulation-Based Inference with Variational Autoencoders
Ingår i 2025 International Joint Conference on Neural Networks (IJCNN), 2025
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Exploiting the Asymmetric Uncertainty Structure of Pre-trained VLMs on the Unit Hypersphere
2025
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Accelerating Fair Federated Learning: Adaptive Federated Adam
Ingår i IEEE Transactions on Machine Learning in Communications and Networking, s. 1017-1032, 2024
- DOI för Accelerating Fair Federated Learning: Adaptive Federated Adam
- Ladda ner fulltext (pdf) av Accelerating Fair Federated Learning: Adaptive Federated Adam
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Ingår i Artificial Intelligence in the Life Sciences, 2024
- DOI för Federated learning for predicting compound mechanism of action based on image-data from cell painting
- Ladda ner fulltext (pdf) av Federated learning for predicting compound mechanism of action based on image-data from cell painting
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Ingår i Expert systems with applications, 2024
- DOI för Data management of scientific applications in a reinforcement learning-based hierarchical storage system
- Ladda ner fulltext (pdf) av Data management of scientific applications in a reinforcement learning-based hierarchical storage system
Alla publikationer
Artiklar i tidskrift
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Accelerating Fair Federated Learning: Adaptive Federated Adam
Ingår i IEEE Transactions on Machine Learning in Communications and Networking, s. 1017-1032, 2024
- DOI för Accelerating Fair Federated Learning: Adaptive Federated Adam
- Ladda ner fulltext (pdf) av Accelerating Fair Federated Learning: Adaptive Federated Adam
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Ingår i Artificial Intelligence in the Life Sciences, 2024
- DOI för Federated learning for predicting compound mechanism of action based on image-data from cell painting
- Ladda ner fulltext (pdf) av Federated learning for predicting compound mechanism of action based on image-data from cell painting
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Ingår i Expert systems with applications, 2024
- DOI för Data management of scientific applications in a reinforcement learning-based hierarchical storage system
- Ladda ner fulltext (pdf) av Data management of scientific applications in a reinforcement learning-based hierarchical storage system
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Toward efficient resource utilization at edge nodes in federated learning
Ingår i Progress in Artificial Intelligence, s. 101-117, 2024
- DOI för Toward efficient resource utilization at edge nodes in federated learning
- Ladda ner fulltext (pdf) av Toward efficient resource utilization at edge nodes in federated learning
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Efficient Hierarchical Storage Management Empowered by Reinforcement Learning
Ingår i IEEE Transactions on Knowledge and Data Engineering, s. 5780-5793, 2023
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Contributions of cell behavior to geometric order in embryonic cartilage
Ingår i PloS Computational Biology, 2023
- DOI för Contributions of cell behavior to geometric order in embryonic cartilage
- Ladda ner fulltext (pdf) av Contributions of cell behavior to geometric order in embryonic cartilage
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FedQAS: Privacy-Aware Machine Reading Comprehension with Federated Learning
Ingår i Applied Sciences, 2022
- DOI för FedQAS: Privacy-Aware Machine Reading Comprehension with Federated Learning
- Ladda ner fulltext (pdf) av FedQAS: Privacy-Aware Machine Reading Comprehension with Federated Learning
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CBMOS: a GPU-enabled Python framework for the numerical study of center-based models
Ingår i BMC Bioinformatics, 2022
- DOI för CBMOS: a GPU-enabled Python framework for the numerical study of center-based models
- Ladda ner fulltext (pdf) av CBMOS: a GPU-enabled Python framework for the numerical study of center-based models
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Living in darkness: Exploring adaptation of Proteus anguinus in 3 dimensions by X-ray imaging
Ingår i GigaScience, 2022
- DOI för Living in darkness: Exploring adaptation of Proteus anguinus in 3 dimensions by X-ray imaging
- Ladda ner fulltext (pdf) av Living in darkness: Exploring adaptation of Proteus anguinus in 3 dimensions by X-ray imaging
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Identification of dynamic mass-action biochemical reaction networks using sparse Bayesian methods
Ingår i PloS Computational Biology, 2022
- DOI för Identification of dynamic mass-action biochemical reaction networks using sparse Bayesian methods
- Ladda ner fulltext (pdf) av Identification of dynamic mass-action biochemical reaction networks using sparse Bayesian methods
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Convolutional Neural Networks as Summary Statistics for Approximate Bayesian Computation
Ingår i IEEE/ACM Transactions on Computational Biology & Bioinformatics, s. 3353-3365, 2022
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Ingår i Nature Communications, 2022
- DOI för Altered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration
- Ladda ner fulltext (pdf) av Altered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration
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Ingår i PloS Computational Biology, 2022
- DOI för Systematic comparison of modeling fidelity levels and parameter inference settings applied to negative feedback gene regulation
- Ladda ner fulltext (pdf) av Systematic comparison of modeling fidelity levels and parameter inference settings applied to negative feedback gene regulation
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Surface flow for colonial integration in reef-building corals
Ingår i Current Biology, s. 2596-2609, 2022
- DOI för Surface flow for colonial integration in reef-building corals
- Ladda ner fulltext (pdf) av Surface flow for colonial integration in reef-building corals
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Ingår i F1000 Research, s. 513-513, 2021
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Ingår i Journal of Chemical Physics, 2021
- DOI för A multiscale compartment-based model of stochastic gene regulatory networks using hitting-time analysis
- Ladda ner fulltext (pdf) av A multiscale compartment-based model of stochastic gene regulatory networks using hitting-time analysis
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Ingår i BMC Bioinformatics, 2021
- DOI för Accelerated regression-based summary statistics for discrete stochastic systems via approximate simulators
- Ladda ner fulltext (pdf) av Accelerated regression-based summary statistics for discrete stochastic systems via approximate simulators
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The machine learning life cycle and the cloud: implications for drug discovery.
Ingår i Expert Opinion on Drug Discovery, s. 1071-1079, 2021
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Scalable machine learning-assisted model exploration and inference using Sciope
Ingår i Bioinformatics, s. 279-281, 2021
- DOI för Scalable machine learning-assisted model exploration and inference using Sciope
- Ladda ner fulltext (pdf) av Scalable machine learning-assisted model exploration and inference using Sciope
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Epidemiological modeling in StochSS Live!
Ingår i Bioinformatics, s. 2787-2788, 2021
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Ingår i GigaScience, s. 1-14, 2021
- DOI för Rapid development of cloud-native intelligent data pipelines for scientific data streams using the HASTE Toolkit
- Ladda ner fulltext (pdf) av Rapid development of cloud-native intelligent data pipelines for scientific data streams using the HASTE Toolkit
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Deep-learning models for lipid nanoparticle-based drug delivery
Ingår i Nanomedicine, s. 1097-1110, 2021
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Impact of Force Function Formulations on the Numerical Simulation of Centre-Based Models.
Ingår i Bulletin of Mathematical Biology, 2020
- DOI för Impact of Force Function Formulations on the Numerical Simulation of Centre-Based Models.
- Ladda ner fulltext (pdf) av Impact of Force Function Formulations on the Numerical Simulation of Centre-Based Models.
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Hierarchical algorithm for the reaction–diffusion master equation
Ingår i Journal of Chemical Physics, 2020
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Ingår i Mathematical Biosciences, 2020
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Ingår i Bioinformatics, s. 5199-5206, 2019
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A 3D multiscale model to explore the role of EGFR overexpression in tumourigenesis
Ingår i Bulletin of Mathematical Biology, s. 2323-2344, 2019
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BAMSI: a multi-cloud service for scalable distributed filtering of massive genome data
Ingår i BMC Bioinformatics, 2018
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Robustness analysis of spatiotemporal models in the presence of extrinsic fluctuations
Ingår i SIAM Journal on Applied Mathematics, s. 1157-1183, 2017
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Mesoscopic-microscopic spatial stochastic simulation with automatic system partitioning
Ingår i Journal of Chemical Physics, 2017
- DOI för Mesoscopic-microscopic spatial stochastic simulation with automatic system partitioning
- Ladda ner fulltext (pdf) av Mesoscopic-microscopic spatial stochastic simulation with automatic system partitioning
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Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage
Ingår i eLIFE, 2017
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Ingår i SIAM Journal on Scientific Computing, 2016
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Mesoscopic modeling of stochastic reaction–diffusion kinetics in the subdiffusive regime
Ingår i Multiscale Modeling & simulation, s. 668-707, 2016
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Analysis and design of jump coefficients in discrete stochastic diffusion models
Ingår i SIAM Journal on Scientific Computing, 2016
- DOI för Analysis and design of jump coefficients in discrete stochastic diffusion models
- Ladda ner fulltext (pdf) av Analysis and design of jump coefficients in discrete stochastic diffusion models
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Stochastic Simulation Service: Bridging the gap between the computational expert and the biologist
Ingår i PloS Computational Biology, 2016
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GillesPy: A Python package for stochastic model building and simulation
Ingår i IEEE Life Sciences Letters, s. 35-38, 2016
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Analysis of neural crest-derived clones reveals novel aspects of facial development
Ingår i Science Advances, 2016
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Accuracy of the Michaelis–Menten approximation when analysing effects of molecular noise
Ingår i Journal of the Royal Society Interface, 2015
- DOI för Accuracy of the Michaelis–Menten approximation when analysing effects of molecular noise
- Ladda ner fulltext (pdf) av Accuracy of the Michaelis–Menten approximation when analysing effects of molecular noise
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Reaction rates for mesoscopic reaction-diffusion kinetics
Ingår i Physical Review E. Statistical, Nonlinear, and Soft Matter Physics, 2015
- DOI för Reaction rates for mesoscopic reaction-diffusion kinetics
- Ladda ner fulltext (pdf) av Reaction rates for mesoscopic reaction-diffusion kinetics
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Ingår i Journal of Computational Physics, s. 89-100, 2014
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Reaction-diffusion master equation in the microscopic limit
Ingår i Physical Review E. Statistical, Nonlinear, and Soft Matter Physics, 2012
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Ingår i Multiscale Modeling & simulation, s. 585-611, 2012
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Ingår i BMC Systems Biology, 2012
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CellMC: a multiplatform model compiler for the Cell Broadband Engine and x86
Ingår i Bioinformatics, s. 426-428, 2010
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Incorporating active transport of cellular cargo in stochastic mesoscopic models of living cells
Ingår i Multiscale Modeling & simulation, s. 1691-1714, 2010
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An adaptive algorithm for simulation of stochastic reaction-diffusion processes
Ingår i Journal of Computational Physics, s. 343-360, 2010
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Simulation of stochastic reaction-diffusion processes on unstructured meshes
Ingår i SIAM Journal on Scientific Computing, s. 1774-1797, 2009
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Ingår i Journal of Chemical Physics, 2008
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Sparse grids and hybrid methods for the chemical master equation
Ingår i BIT Numerical Mathematics, s. 265-283, 2008
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A hierarchy of approximations of the master equation scaled by a size parameter
Ingår i Journal of Scientific Computing, s. 127-151, 2008
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Hybrid method for the chemical master equation
Ingår i Journal of Computational Physics, s. 100-122, 2007
Doktorsavhandlingar, sammanläggning
Kapitel i böcker, delar av antologi
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Multiscale simulation of stochastic reaction–diffusion networks
Ingår i Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology, s. 55-79, Springer, 2017
Konferensbidrag
-
Accelerating Simulation-Based Inference with Variational Autoencoders
Ingår i 2025 International Joint Conference on Neural Networks (IJCNN), 2025
-
Exploiting the Asymmetric Uncertainty Structure of Pre-trained VLMs on the Unit Hypersphere
2025
-
Efficient Hierarchical Storage Management Empowered by Reinforcement Learning Extended Abstract
s. 3869-3870, 2023
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Scalable federated machine learning with FEDn
Ingår i 2022 22nd IEEE/ACM International Symposium on Cluster, Cloud and Internet Computing (CCGrid 2022), s. 555-564, 2022
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Robust and integrative Bayesian neural networks for likelihood-free parameter inference
Ingår i 2022 International Joint Conference on Neural Networks (IJCNN), s. 1-10, 2022
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Smart Resource Management for Data Streaming using an Online Bin-packing Strategy
Ingår i 2020 IEEE International Conference on Big Data (Big Data), s. 2207-2216, 2020
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Ingår i Benchmarking, Measuring, and Optimizing, s. 335-347, 2020
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Adapting the secretary hiring problem for optimal hot–cold tier placement under top-K workloads
Ingår i Proc. 19th International Symposium on Cluster, Cloud, and Grid Computing, s. 576-583, 2019
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Orchestral: a lightweight framework for parallel simulations of cell–cell communication
Ingår i Proc. 14th International Conference on e-Science, s. 168-176, 2018
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Hyperparameter optimization for approximate Bayesian computation
Ingår i Proc. 50th Winter Simulation Conference, s. 1718-1729, 2018
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HarmonicIO: Scalable data stream processing for scientific datasets
Ingår i Proc. 11th International Conference on Cloud Computing, s. 879-882, 2018
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Ingår i Proc. 32nd European Simulation and Modelling Conference, s. 22-27, 2018
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Cost-aware application development and management using CLOUD-METRIC
Ingår i Proc. 7th International Conference on Cloud Computing and Services Science, s. 515-522, 2017
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Surrogate assisted model reduction for stochastic biochemical reaction networks
Ingår i Proc. 49th Winter Simulation Conference, s. 1773-1783, 2017
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SNIC Science Cloud (SSC): A national-scale cloud infrastructure for Swedish academia
Ingår i Proc. 13th International Conference on e-Science, s. 219-227, 2017
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Automatic and portable cloud deployment for scientific simulations
Ingår i Proc. 12th International Conference on High Performance Computing and Simulation, s. 374-381, 2014
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Scientific analysis by queries in extended SPARQL over a scalable e-Science data store
Ingår i Proc. 9th International Conference on e-Science, s. 98-106, 2013
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Ingår i Proc. 3rd International Conference on Bioinformatics Models, Methods and Algorithms, s. 290-294, 2012
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Reducing complexity in management of eScience computations
Ingår i Proc. 12th International Symposium on Cluster, Cloud and Grid Computing, s. 845-852, 2012
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Adaptive stochastic hybrid simulation of biochemical reaction-diffusion models
Ingår i Proc. 3rd International Conference on Foundations of Systems Biology in Engineering, s. 4, 2009
Licentiatavhandlingar, sammanläggning
Manuskript (preprint)
Rapporter
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2011
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Incorporating active transport of cellular cargo in stochastic mesoscopic models of living cells
2010
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An adaptive algorithm for simulation of stochastic reaction-diffusion processes
2009
-
Simulation of stochastic reaction-diffusion processes on unstructured meshes
2008
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2007
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A hierarchy of approximations of the master equation scaled by a size parameter
2007
-
Hybrid method for the chemical master equation
2006