Gunilla Westermark
Professor i medicinsk strukturbiologi särskilt proteinkonformationssjukdomar vid Institutionen för medicinsk cellbiologi; Forskargrupp Gunilla Westermark
- Telefon:
- 018-471 41 69
- Fax:
- 018-471 40 59
- E-post:
- gunilla.westermark@mcb.uu.se
- Besöksadress:
- BMC
Husargatan 3
751 23 Uppsala - Postadress:
- Box 571
751 23 UPPSALA
Publikationer
Senaste publikationer
Ingår i Frontiers in Cellular Neuroscience, 2025
- DOI för Rodent islet amyloid polypeptide (IAPP) selectively enhances GABAA receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
- Ladda ner fulltext (pdf) av Rodent islet amyloid polypeptide (IAPP) selectively enhances GABAA receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
The question of strains in AA amyloidosis
Ingår i Scientific Reports, 2025
- DOI för The question of strains in AA amyloidosis
- Ladda ner fulltext (pdf) av The question of strains in AA amyloidosis
Efficient Vascular and Neural Engraftment of Stem Cell–Derived Islets
Ingår i Diabetes, s. 1127-1139, 2024
The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
Ingår i EMBO Molecular Medicine, s. 2024-2042, 2024
- DOI för The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
- Ladda ner fulltext (pdf) av The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
Insulin release from isolated cat islets of Langerhans
Ingår i Domestic Animal Endocrinology, 2024
- DOI för Insulin release from isolated cat islets of Langerhans
- Ladda ner fulltext (pdf) av Insulin release from isolated cat islets of Langerhans
Alla publikationer
Artiklar i tidskrift
Ingår i Frontiers in Cellular Neuroscience, 2025
- DOI för Rodent islet amyloid polypeptide (IAPP) selectively enhances GABAA receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
- Ladda ner fulltext (pdf) av Rodent islet amyloid polypeptide (IAPP) selectively enhances GABAA receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
The question of strains in AA amyloidosis
Ingår i Scientific Reports, 2025
- DOI för The question of strains in AA amyloidosis
- Ladda ner fulltext (pdf) av The question of strains in AA amyloidosis
Efficient Vascular and Neural Engraftment of Stem Cell–Derived Islets
Ingår i Diabetes, s. 1127-1139, 2024
The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
Ingår i EMBO Molecular Medicine, s. 2024-2042, 2024
- DOI för The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
- Ladda ner fulltext (pdf) av The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
Insulin release from isolated cat islets of Langerhans
Ingår i Domestic Animal Endocrinology, 2024
- DOI för Insulin release from isolated cat islets of Langerhans
- Ladda ner fulltext (pdf) av Insulin release from isolated cat islets of Langerhans
CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells
Ingår i Journal of Molecular Endocrinology, 2023
- DOI för CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells
- Ladda ner fulltext (pdf) av CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells
Phosphorylated α-synuclein in skin Schwann cells: a new biomarker for multiple system atrophy
Ingår i Brain, s. 1065-1074, 2023
Studies on alpha-synuclein and islet amyloid polypeptide interaction
Ingår i Frontiers in Molecular Biosciences, 2023
- DOI för Studies on alpha-synuclein and islet amyloid polypeptide interaction
- Ladda ner fulltext (pdf) av Studies on alpha-synuclein and islet amyloid polypeptide interaction
Ingår i Upsala Journal of Medical Sciences, 2022
- DOI för Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital
- Ladda ner fulltext (pdf) av Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital
Amyloid fibril structure from the vascular variant of systemic AA amyloidosis
Ingår i Nature Communications, 2022
- DOI för Amyloid fibril structure from the vascular variant of systemic AA amyloidosis
- Ladda ner fulltext (pdf) av Amyloid fibril structure from the vascular variant of systemic AA amyloidosis
AA amyloid in human food chain is a possible biohazard
Ingår i Scientific Reports, 2021
- DOI för AA amyloid in human food chain is a possible biohazard
- Ladda ner fulltext (pdf) av AA amyloid in human food chain is a possible biohazard
Enhanced detection of ATTR amyloid using a nanofibril-based assay
Ingår i Amyloid, s. 158-167, 2021
- DOI för Enhanced detection of ATTR amyloid using a nanofibril-based assay
- Ladda ner fulltext (pdf) av Enhanced detection of ATTR amyloid using a nanofibril-based assay
Ingår i International Journal of Biological Macromolecules, s. 428-435, 2021
Ingår i Journal of enzyme inhibition and medicinal chemistry (Print), s. 517-524, 2021
- DOI för Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
- Ladda ner fulltext (pdf) av Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
Ingår i American Journal of Transplantation, s. 2090-2099, 2021
The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
Ingår i International Journal of Molecular Sciences, 2021
- DOI för The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
- Ladda ner fulltext (pdf) av The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
Ingår i Nature Communications, 2019
- DOI för Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids
- Ladda ner fulltext (pdf) av Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids
3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
Ingår i PLOS ONE, 2019
- DOI för 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
- Ladda ner fulltext (pdf) av 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis
Ingår i Amyloid, s. 34-44, 2019
- DOI för Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis
- Ladda ner fulltext (pdf) av Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis
Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2018
Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission
Ingår i Cold Spring Harbor Perspectives in Medicine, 2018
Ingår i American Journal of Transplantation, s. 1735-1744, 2018
- DOI för Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
- Ladda ner fulltext (pdf) av Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
Protofibrillar and Fibrillar Amyloid-beta Binding Proteins in Cerebrospinal Fluid
Ingår i Journal of Alzheimer's Disease, s. 1053-1064, 2018
The Cryo-EM Method Micro-ED Structure Determination of Type II Diabetes-Related Protein Segments
Ingår i Biophysical Journal, 2017
Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets.
Ingår i Endocrine Connections, s. 458-468, 2017
- DOI för Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets.
- Ladda ner fulltext (pdf) av Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets.
Ingår i eLIFE, 2017
- DOI för Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important or cytotoxicity
- Ladda ner fulltext (pdf) av Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important or cytotoxicity
Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
Ingår i Journal of Neuroscience, s. 11835-11853, 2017
- DOI för Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
- Ladda ner fulltext (pdf) av Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
Systemic AA amyloidosis in the red fox (Vulpes vulpes)
Ingår i Protein Science, s. 2312-2318, 2017
Seed-dependent templating of murine AA amyloidosis
Ingår i Amyloid, s. 140-141, 2017
Islet amyloid in recent-onset type 1 diabetes-the DiViD study
Ingår i Upsala Journal of Medical Sciences, s. 201-203, 2017
- DOI för Islet amyloid in recent-onset type 1 diabetes-the DiViD study
- Ladda ner fulltext (pdf) av Islet amyloid in recent-onset type 1 diabetes-the DiViD study
Ingår i Upsala Journal of Medical Sciences, s. 149-159, 2017
- DOI för Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-beta H1 cells
- Ladda ner fulltext (pdf) av Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-beta H1 cells
The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
Ingår i Diabetologia, s. 1522-1533, 2017
- DOI för The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
- Ladda ner fulltext (pdf) av The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
Ingår i ACS Medicinal Chemistry Letters, s. 368-373, 2016
Electron tomography reveals the fibril structure and lipid interactions in amyloid deposits
Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 5604-5609, 2016
Ingår i Immunobiology, s. 1162-1162, 2016
C4b-binding Protein Protects -Cells from Islet Amyloid Polypeptide-induced Cytotoxicity
Ingår i Journal of Biological Chemistry, s. 21644-21655, 2016
Ingår i Amyloid, s. 98-108, 2016
Ingår i American Journal of Pathology, s. 834-846, 2015
C4BP inhibits IAPP-mediated inflammasome activation in type 2 diabetes
Ingår i Molecular Immunology, s. 152-152, 2015
Eighty years of research on islet amyloidosis in Uppsala
Ingår i Upsala Journal of Medical Sciences, s. 117-123, 2015
Ingår i Journal of Biological Chemistry, s. 15121-15132, 2015
High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
Ingår i PLOS ONE, 2014
- DOI för High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
- Ladda ner fulltext (pdf) av High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
Transthyretin-derived amyloidosis: Probably a common cause of lumbar spinal stenosis
Ingår i Upsala Journal of Medical Sciences, s. 223-228, 2014
C4b-binding protein inhibits islet amyloid polypeptide-induced cytotoxicity and inflammation
Ingår i Molecular Immunology, s. 224-224, 2014
Ingår i Disease Models and Mechanisms, s. 659-665, 2014
- DOI för The chaperone domain BRICHOS prevents CNS toxicity of amyloid-beta peptide in Drosophila melanogaster
- Ladda ner fulltext (pdf) av The chaperone domain BRICHOS prevents CNS toxicity of amyloid-beta peptide in Drosophila melanogaster
Ingår i Cell Transplantation, s. 139-151, 2014
- DOI för Birth and Death of Human beta-Cells in Pancreases From Cadaver Donors, Autopsies, Surgical Specimens, and Islets Transplanted Into Mice
- Ladda ner fulltext (pdf) av Birth and Death of Human beta-Cells in Pancreases From Cadaver Donors, Autopsies, Surgical Specimens, and Islets Transplanted Into Mice
Ingår i PLOS ONE, 2013
- DOI för Depletion of Spleen Macrophages Delays AA Amyloid Development: A Study Performed in the Rapid Mouse Model of AA Amyloidosis
- Ladda ner fulltext (pdf) av Depletion of Spleen Macrophages Delays AA Amyloid Development: A Study Performed in the Rapid Mouse Model of AA Amyloidosis
Ingår i Journal of labelled compounds & radiopharmaceuticals, 2013
Efficient Amyloid A Clearance in the Absence of Immunoglobulins and Complement Factors
Ingår i American Journal of Pathology, s. 1297-1307, 2013
Ingår i Journal of Biological Chemistry, s. 10824-10833, 2012
Ingår i Archives of Dermatological Research, s. 377-386, 2012
Ingår i Neurobiology of Aging, 2012
Extensive amyloid formation in transplanted microencapsulated mouse and human islets
Ingår i Amyloid, s. 87-93, 2012
Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts
Ingår i Transplantation, s. 219-223, 2012
AA-Amyloid is cleared by endogenous immunological mechanisms
Ingår i Amyloid, s. 138-145, 2012
Complement inhibitor C4b-binding protein is involved in protein AA amyloidosis
Ingår i Immunobiology, s. 1158-1158, 2012
Ingår i Amyloid, s. 47-52, 2011
Ingår i American Journal of Pathology, s. 2286-2298, 2011
Ingår i American Journal of Pathology, s. 2632-2640, 2011
Ingår i Scandinavian Journal of Immunology, s. 535-540, 2009
Ingår i PloS one, 2009
Ingår i Experimental diabetes research, s. 528354, 2008
Artiklar, forskningsöversikt
Ingår i Chemical Reviews, s. 1845-1893, 2021
Current and future treatment of amyloid diseases
Ingår i Journal of Internal Medicine, s. 177-202, 2016
Islet Amyloid Polypeptide and Diabetes
Ingår i Current protein and peptide science, s. 330-337, 2013
Islet amyloid polypeptide, islet amyloid, and diabetes mellitus
Ingår i Physiological Reviews, s. 795-826, 2011
Ingår i The FEBS Journal, s. 3918-3929, 2011
Prion-like aggregates: infectious agents in human disease
Ingår i Trends in Molecular Medicine, s. 501-507, 2010
Serum amyloid A and protein AA: molecular mechanisms of a transmissible amyloidosis
Ingår i FEBS Letters, s. 2685-2690, 2009
Ingår i Experimental diabetes research, s. 562985, 2008
Kapitel i böcker, delar av antologi
AA Amyloidosis: Pathogenesis and Targeted Therapy
Ingår i Annual Review Of Pathology, s. 321-344, ANNUAL REVIEWS, 2015
Konferensbidrag
Electron tomography analysis of Islet Amyloid Poly-Peptide aggregates in drosophila melanogaster
2017
2014
Ingår i Electron tomography, 2014