Gunilla Westermark

Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis

Westermark, Gunilla; Berg, Svante; Eldhagen, Per; Damjanovic Vesterlund, Justina et al.

Ingår i Amyloid, s. 125-134, 2026

• DOI för Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis
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Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress

Cen, Jing; Ivis, Anja; Vasylovska, Svitlana; Adjieva, Kina et al.

Ingår i Diabetologia, s. 436-450, 2026

• DOI för Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress
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Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells

Netsyk, Olga; Korol, Sergiy; Westermark, Gunilla; Birnir, Bryndis et al.

Ingår i Frontiers in Cellular Neuroscience, 2025

• DOI för Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
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The question of strains in AA amyloidosis

Westermark, Gunilla; Nyström, Ebba; Nyström, Sofie; Nilsson, K. Peter R. et al.

Ingår i Scientific Reports, 2025

• DOI för The question of strains in AA amyloidosis
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Efficient Vascular and Neural Engraftment of Stem Cell–Derived Islets

Thorngren, Julia; Brboric, Anja; Vasylovska, Svitlana; Hjelmqvist, Daisy et al.

Ingår i Diabetes, s. 1127-1139, 2024

• DOI för Efficient Vascular and Neural Engraftment of Stem Cell–Derived Islets

Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis

Westermark, Gunilla; Berg, Svante; Eldhagen, Per; Damjanovic Vesterlund, Justina et al.

Ingår i Amyloid, s. 125-134, 2026

• DOI för Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis
• Ladda ner fulltext (pdf) av Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis

Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress

Cen, Jing; Ivis, Anja; Vasylovska, Svitlana; Adjieva, Kina et al.

Ingår i Diabetologia, s. 436-450, 2026

• DOI för Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress
• Ladda ner fulltext (pdf) av Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress

Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells

Netsyk, Olga; Korol, Sergiy; Westermark, Gunilla; Birnir, Bryndis et al.

Ingår i Frontiers in Cellular Neuroscience, 2025

• DOI för Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
• Ladda ner fulltext (pdf) av Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells

The question of strains in AA amyloidosis

Westermark, Gunilla; Nyström, Ebba; Nyström, Sofie; Nilsson, K. Peter R. et al.

Ingår i Scientific Reports, 2025

• DOI för The question of strains in AA amyloidosis
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Efficient Vascular and Neural Engraftment of Stem Cell–Derived Islets

Thorngren, Julia; Brboric, Anja; Vasylovska, Svitlana; Hjelmqvist, Daisy et al.

Ingår i Diabetes, s. 1127-1139, 2024

• DOI för Efficient Vascular and Neural Engraftment of Stem Cell–Derived Islets

The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis

Losa, Marco; Emmenegger, Marc; De Rossi, Pierre; Schürch, Patrick M. et al.

Ingår i EMBO Molecular Medicine, s. 2024-2042, 2024

• DOI för The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
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Insulin release from isolated cat islets of Langerhans

Strage, Emma M.; Ley, Cecilia; Westermark, Gunilla T.; Tengholm, Anders

Ingår i Domestic Animal Endocrinology, 2024

• DOI för Insulin release from isolated cat islets of Langerhans
• Ladda ner fulltext (pdf) av Insulin release from isolated cat islets of Langerhans

CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells

Shi, Ruifeng; Cen, Jing; Westermark, Gunilla; Zhao, Sheng et al.

Ingår i Journal of Molecular Endocrinology, 2023

• DOI för CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells
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Phosphorylated α-synuclein in skin Schwann cells: a new biomarker for multiple system atrophy

Donadio, Vincenzo; Incensi, Alex; Rizzo, Giovanni; Westermark, Gunilla T. et al.

Ingår i Brain, s. 1065-1074, 2023

• DOI för Phosphorylated α-synuclein in skin Schwann cells: a new biomarker for multiple system atrophy

Studies on alpha-synuclein and islet amyloid polypeptide interaction

Wang, Ye; Bergström, Joakim; Ingelsson, Martin; Westermark, Gunilla

Ingår i Frontiers in Molecular Biosciences, 2023

• DOI för Studies on alpha-synuclein and islet amyloid polypeptide interaction
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Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital

Vesterlund Damjanovic, Justina; Ihse, Elisabet; Thelander, Ulrika; Zancanaro, Alice et al.

Ingår i Upsala Journal of Medical Sciences, 2022

• DOI för Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital
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Amyloid fibril structure from the vascular variant of systemic AA amyloidosis

Banerjee, Sambhasan; Baur, Julian; Daniel, Christoph; Pfeiffer, Peter Benedikt et al.

Ingår i Nature Communications, 2022

• DOI för Amyloid fibril structure from the vascular variant of systemic AA amyloidosis
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Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity

Floris, Sonia; Fais, Antonella; Medda, Rosaria; Pintus, Francesca et al.

Ingår i Journal of Enzyme Inhibition and Medicinal Chemistry, s. 517-524, 2021

• DOI för Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
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AA amyloid in human food chain is a possible biohazard

Rising, Anna; Gherardi, Paola; Chen, Gefei; Johansson, Jan et al.

Ingår i Scientific Reports, 2021

• DOI för AA amyloid in human food chain is a possible biohazard
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Enhanced detection of ATTR amyloid using a nanofibril-based assay

Rahman, M. Mahafuzur; Schmuck, Benjamin; Hansson, Henrik; Hard, Torleif et al.

Ingår i Amyloid, s. 158-167, 2021

• DOI för Enhanced detection of ATTR amyloid using a nanofibril-based assay
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A new biological prospective for the 2-phenylbenzofurans as inhibitors of α-glucosidase and of the islet amyloid polypeptide formation

Delogu, Giovanna Lucia; Era, Benedetta; Floris, Sonia; Medda, Rosaria et al.

Ingår i International Journal of Biological Macromolecules, s. 428-435, 2021

• DOI för A new biological prospective for the 2-phenylbenzofurans as inhibitors of α-glucosidase and of the islet amyloid polypeptide formation

Formation of amyloid in encapsulated human pancreatic and human stem cell-generated beta cell implants

Van Hulle, Freya; De Groot, Kaat; Stangé, Geert; Suenens, Krista et al.

Ingår i American Journal of Transplantation, s. 2090-2099, 2021

• DOI för Formation of amyloid in encapsulated human pancreatic and human stem cell-generated beta cell implants

The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level

Wang, Ye; Westermark, Gunilla

Ingår i International Journal of Molecular Sciences, 2021

• DOI för The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
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Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids

Liberta, Falk; Loerch, Sarah; Rennegarbege, Matthies; Schierhorn, Angelika et al.

Ingår i Nature Communications, 2019

• DOI för Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids
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3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster

Xie, Ling; Gu, Xiaohong; Okamoto, Kenta; Westermark, Gunilla et al.

Ingår i PLOS ONE, 2019

• DOI för 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
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Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis

Panahi, Aida Vahdat Shariat; Hultman, Per; Ollinger, Karin; Westermark, Gunilla T. et al.

Ingår i Amyloid, s. 34-44, 2019

• DOI för Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis
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The BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells

Oskarsson, Marie E.; Hermansson, Erik; Wang, Ye; Welsh, Nils et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2018

• DOI för The BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells

Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission

Westermark, Gunilla; Faendrich, Marcus; Lundmark, Katarzyna; Westermark, Per

Ingår i Cold Spring Harbor Perspectives in Medicine, 2018

• DOI för Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission

Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

Carlsson, Per-Ola; Espes, Daniel; Sedigh, Amir; Rotem, Avi et al.

Ingår i American Journal of Transplantation, s. 1735-1744, 2018

• DOI för Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
• Ladda ner fulltext (pdf) av Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

Protofibrillar and Fibrillar Amyloid-beta Binding Proteins in Cerebrospinal Fluid

Rahman, M. Mahafuzur; Westermark, Gunilla; Zetterberg, Henrik; Hard, Torleif et al.

Ingår i Journal of Alzheimer's Disease, s. 1053-1064, 2018

• DOI för Protofibrillar and Fibrillar Amyloid-beta Binding Proteins in Cerebrospinal Fluid

The Cryo-EM Method Micro-ED Structure Determination of Type II Diabetes-Related Protein Segments

Krotee, Pascal; Rodriguez, Jose A.; Sawaya, Michael R.; Cascio, Duilio et al.

Ingår i Biophysical Journal, 2017

Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets.

Ullsten, Sara; Bohman, Sara; Oskarsson, Marie E; Nilsson, K Peter R et al.

Ingår i Endocrine Connections, s. 458-468, 2017

• DOI för Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets.
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Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important or cytotoxicity

Krotee, Pascal; Rodriguez, Jose A.; Sawaya, Michael R.; Cascio, Duilio et al.

Ingår i eLIFE, 2017

• DOI för Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important or cytotoxicity
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Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes

Rostami, Jinar; Holmqvist, Staffan; Lindström, Veronica; Sigvardson, Jessica et al.

Ingår i Journal of Neuroscience, s. 11835-11853, 2017

• DOI för Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
• Ladda ner fulltext (pdf) av Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes

Systemic AA amyloidosis in the red fox (Vulpes vulpes)

Rising, Anna; Cederlund, Ella; Palmberg, Carina; Uhlhorn, Henrik et al.

Ingår i Protein Science, s. 2312-2318, 2017

• DOI för Systemic AA amyloidosis in the red fox (Vulpes vulpes)

Seed-dependent templating of murine AA amyloidosis

Nyström, Sofie; Panahi, Aida Vahdat Shariat; Nilsson, K. Peter R.; Westermark, Per et al.

Ingår i Amyloid, s. 140-141, 2017

• DOI för Seed-dependent templating of murine AA amyloidosis

Islet amyloid in recent-onset type 1 diabetes-the DiViD study

Westermark, Gunilla T.; Krogvold, Lars; Dahl-Jorgensen, Knut; Ludvigsson, Johnny

Ingår i Upsala Journal of Medical Sciences, s. 201-203, 2017

• DOI för Islet amyloid in recent-onset type 1 diabetes-the DiViD study
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Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-beta H1 cells

Krizhanovskii, Camilla; Fred, Rikard G; Oskarsson, Marie E.; Westermark, Gunilla T. et al.

Ingår i Upsala Journal of Medical Sciences, s. 149-159, 2017

• DOI för Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-beta H1 cells
• Ladda ner fulltext (pdf) av Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-beta H1 cells

The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation

Kulak, Klaudia; Westermark, Gunilla; Papac-Milicevic, Nikolina; Renström, Erik et al.

Ingår i Diabetologia, s. 1522-1533, 2017

• DOI för The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
• Ladda ner fulltext (pdf) av The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation

C-11 and F-18 Radiolabeling of Tetra- and Pentathiophenes as PET-Ligands for Amyloid Protein Aggregates

Nordeman, Patrik; Johansson, Leif B. G.; Back, Marcus; Estrada, Sergio et al.

Ingår i ACS Medicinal Chemistry Letters, s. 368-373, 2016

• DOI för C-11 and F-18 Radiolabeling of Tetra- and Pentathiophenes as PET-Ligands for Amyloid Protein Aggregates

Electron tomography reveals the fibril structure and lipid interactions in amyloid deposits

Kollmer, Marius; Meinhardt, Katrin; Haupt, Christian; Liberta, Falk et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 5604-5609, 2016

• DOI för Electron tomography reveals the fibril structure and lipid interactions in amyloid deposits

The complement regulator C4b-binding protein inhibits islet amyloid polypeptide-induced inflammasome activation

Kulak, Klaudia; Westermark, Gunilla; Papac-Milicevic, Nikolina; Renström, Erik et al.

Ingår i Immunobiology, s. 1162-1162, 2016

• DOI för The complement regulator C4b-binding protein inhibits islet amyloid polypeptide-induced inflammasome activation

C4b-binding Protein Protects -Cells from Islet Amyloid Polypeptide-induced Cytotoxicity

Sjölander, Jonatan; Byman, Elin; Kulak, Klaudia; Nilsson, Sara C. et al.

Ingår i Journal of Biological Chemistry, s. 21644-21655, 2016

• DOI för C4b-binding Protein Protects -Cells from Islet Amyloid Polypeptide-induced Cytotoxicity

Establishing the fluorescent amyloid ligand h-FTAA for studying human tissues with systemic and localized amyloid

Sjölander, Daniel; Roecken, Christoph; Westermark, Per; Westermark, Gunilla T. et al.

Ingår i Amyloid, s. 98-108, 2016

• DOI för Establishing the fluorescent amyloid ligand h-FTAA for studying human tissues with systemic and localized amyloid

In Vivo Seeding and Cross-Seeding of Localized Amyloidosis A Molecular Link between Type 2 Diabetes and Alzheimer Disease

Oskarsson, Marie E.; Paulsson, Johan F.; Schultz, Sebastian W.; Ingelsson, Martin et al.

Ingår i American Journal of Pathology, s. 834-846, 2015

• DOI för In Vivo Seeding and Cross-Seeding of Localized Amyloidosis A Molecular Link between Type 2 Diabetes and Alzheimer Disease

C4BP inhibits IAPP-mediated inflammasome activation in type 2 diabetes

King, Ben; Kulak, Klaudia; Papac-Milicevic, Nikolina; Westermark, Gunilla et al.

Ingår i Molecular Immunology, s. 152-152, 2015

Eighty years of research on islet amyloidosis in Uppsala

Westermark, Gunilla T.; Oskarsson, Marie; Andersson, Arne; Westermark, Per

Ingår i Upsala Journal of Medical Sciences, s. 117-123, 2015

• DOI för Eighty years of research on islet amyloidosis in Uppsala

Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis

Oskarsson, Marie E.; Singh, Kailash; Wang, Jian; Vlodavsky, Israel et al.

Ingår i Journal of Biological Chemistry, s. 15121-15132, 2015

• DOI för Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis

High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus

Paulsson, Johan F.; Ludvigsson, Johnny; Carlsson, Annelie; Casas, Rosaura et al.

Ingår i PLOS ONE, 2014

• DOI för High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
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Transthyretin-derived amyloidosis: Probably a common cause of lumbar spinal stenosis

Westermark, Per; Westermark, Gunilla T.; Suhr, Ole B.; Berg, Svante

Ingår i Upsala Journal of Medical Sciences, s. 223-228, 2014

• DOI för Transthyretin-derived amyloidosis: Probably a common cause of lumbar spinal stenosis

C4b-binding protein inhibits islet amyloid polypeptide-induced cytotoxicity and inflammation

Nilsson, Sara C.; King, Ben C.; Sjolander, Jonatan; Storm, Petter et al.

Ingår i Molecular Immunology, s. 224-224, 2014

The chaperone domain BRICHOS prevents CNS toxicity of amyloid-beta peptide in Drosophila melanogaster

Hermansson, Erik; Schultz, Sebastian; Crowther, Damian; Linse, Sara et al.

Ingår i Disease Models and Mechanisms, s. 659-665, 2014

• DOI för The chaperone domain BRICHOS prevents CNS toxicity of amyloid-beta peptide in Drosophila melanogaster
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Birth and Death of Human beta-Cells in Pancreases From Cadaver Donors, Autopsies, Surgical Specimens, and Islets Transplanted Into Mice

Caballero, Francisco; Siniakowicz, Karolina; Hollister-Lock, Jennifer; Duran, Luisa et al.

Ingår i Cell Transplantation, s. 139-151, 2014

• DOI för Birth and Death of Human beta-Cells in Pancreases From Cadaver Donors, Autopsies, Surgical Specimens, and Islets Transplanted Into Mice
• Ladda ner fulltext (pdf) av Birth and Death of Human beta-Cells in Pancreases From Cadaver Donors, Autopsies, Surgical Specimens, and Islets Transplanted Into Mice

Depletion of Spleen Macrophages Delays AA Amyloid Development: A Study Performed in the Rapid Mouse Model of AA Amyloidosis

Lundmark, Katarzyna; Shariatpanahi, Aida Vahdat; Westermark, Gunilla T.

Ingår i PLOS ONE, 2013

• DOI för Depletion of Spleen Macrophages Delays AA Amyloid Development: A Study Performed in the Rapid Mouse Model of AA Amyloidosis
• Ladda ner fulltext (pdf) av Depletion of Spleen Macrophages Delays AA Amyloid Development: A Study Performed in the Rapid Mouse Model of AA Amyloidosis

Efficient Amyloid A Clearance in the Absence of Immunoglobulins and Complement Factors

Sponarova, Jana; Nuvolone, Mario; Whicher, Charlotte; Frei, Nathalie et al.

Ingår i American Journal of Pathology, s. 1297-1307, 2013

• DOI för Efficient Amyloid A Clearance in the Absence of Immunoglobulins and Complement Factors

C-11 and F-18 radiolabeling of tetra and pentatiophenes as PET-ligands for misfolded protein aggregates

Nordeman, Patrik; Hall, Håkan; Hammarstrom, Per; Nilsson, Peter R. et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2013

Islet Amyloid Polypeptide Triggers Limited Complement Activation and Binds Complement Inhibitor C4b-binding Protein, Which Enhances Fibril Formation

Sjölander, Jonatan; Westermark, Gunilla T.; Renström, Erik; Blom, Anna M.

Ingår i Journal of Biological Chemistry, s. 10824-10833, 2012

• DOI för Islet Amyloid Polypeptide Triggers Limited Complement Activation and Binds Complement Inhibitor C4b-binding Protein, Which Enhances Fibril Formation

Ichthyin/NIPAL4 localizes to keratins and desmosomes in epidermis and Ichthyin mutations affect epidermal lipid metabolism

Dahlqvist, Johanna; Westermark, Gunilla T.; Vahlquist, Anders; Dahl, Niklas

Ingår i Archives of Dermatological Research, s. 377-386, 2012

• DOI för Ichthyin/NIPAL4 localizes to keratins and desmosomes in epidermis and Ichthyin mutations affect epidermal lipid metabolism

Amyloid neuropathology in the single Arctic APP transgenic model affects interconnected brain regions

Rönnback, Annica; Sagelius, Hanna; Bergstedt, Karin Dillner; Naslund, Jan et al.

Ingår i Neurobiology of Aging, 2012

• DOI för Amyloid neuropathology in the single Arctic APP transgenic model affects interconnected brain regions

Extensive amyloid formation in transplanted microencapsulated mouse and human islets

Bohman, Sara; Westermark, Gunilla

Ingår i Amyloid, s. 87-93, 2012

• DOI för Extensive amyloid formation in transplanted microencapsulated mouse and human islets

Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts

Westermark, Gunilla T.; Davalli, Alberto M.; Secchi, Antonio; Folli, Franco et al.

Ingår i Transplantation, s. 219-223, 2012

• DOI för Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts

AA-Amyloid is cleared by endogenous immunological mechanisms

Nyström, Sofia N.; Westermark, Gunilla T.

Ingår i Amyloid, s. 138-145, 2012

• DOI för AA-Amyloid is cleared by endogenous immunological mechanisms

Complement inhibitor C4b-binding protein is involved in protein AA amyloidosis

Sjölander, Jonatan; Lundmark, Katarzyna; Wetsel, Rick; Blom, Anna M. et al.

Ingår i Immunobiology, s. 1158-1158, 2012

• DOI för Complement inhibitor C4b-binding protein is involved in protein AA amyloidosis

Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease

Lord, Anna; Philipson, Ola; Klingstedt, Therése; Westermark, Gunilla et al.

Ingår i American Journal of Pathology, s. 2286-2298, 2011

• DOI för Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease

PTAA and B10: new approaches to amyloid detection in tissue-evaluation of amyloid detection in tissue with a conjugated polyelectrolyte and a fibril-specific antibody fragment

Kieninger, Barbara; Gioeva, Zarina; Krueger, Sandra; Westermark, Gunilla T. et al.

Ingår i Amyloid, s. 47-52, 2011

• DOI för PTAA and B10: new approaches to amyloid detection in tissue-evaluation of amyloid detection in tissue with a conjugated polyelectrolyte and a fibril-specific antibody fragment

beta-Cell Loss and beta-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition

Jurgens, Catherine A.; Toukatly, Mirna N.; Fligner, Corinne L.; Udayasankar, Jayalakshmi et al.

Ingår i American Journal of Pathology, s. 2632-2640, 2011

• DOI för beta-Cell Loss and beta-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition

Fibrils from designed non-amyloid-related synthetic peptides induce AA-amyloidosis during inflammation in an animal model

Westermark, Per; Lundmark, Katarzyna; Westermark, Gunilla T

Ingår i PloS one, 2009

• DOI för Fibrils from designed non-amyloid-related synthetic peptides induce AA-amyloidosis during inflammation in an animal model

Alkali-degradation of amyloid: an ancient method useful for making monoclonal antibodies against amyloid fibril proteins

Westermark, Gunilla T; Sletten, K; Westermark, Per

Ingår i Scandinavian Journal of Immunology, s. 535-540, 2009

• DOI för Alkali-degradation of amyloid: an ancient method useful for making monoclonal antibodies against amyloid fibril proteins

Importance of aggregated islet amyloid polypeptide for the progressive beta-cell failure in type 2 diabetes and in transplanted human islets

Westermark, Gunilla; Westermark, Per

Ingår i Experimental diabetes research, s. 528354, 2008

• DOI för Importance of aggregated islet amyloid polypeptide for the progressive beta-cell failure in type 2 diabetes and in transplanted human islets

Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes

Milardi, Danilo; Gazit, Ehud; Radford, Sheena E.; Xu, Yong et al.

Ingår i Chemical Reviews, s. 1845-1893, 2021

• DOI för Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes

Current and future treatment of amyloid diseases

Ankarcrona, M.; Winblad, B.; Monteiro, C.; Fearns, C. et al.

Ingår i Journal of Internal Medicine, s. 177-202, 2016

• DOI för Current and future treatment of amyloid diseases

Islet Amyloid Polypeptide and Diabetes

Westermark, Gunilla T.; Westermark, Per

Ingår i Current protein and peptide science, s. 330-337, 2013

• DOI för Islet Amyloid Polypeptide and Diabetes

Islet amyloid polypeptide, islet amyloid, and diabetes mellitus

Westermark, Per; Andersson, Arne; Westermark, Gunilla T.

Ingår i Physiological Reviews, s. 795-826, 2011

• DOI för Islet amyloid polypeptide, islet amyloid, and diabetes mellitus

Localized amyloids important in diseases outside the brain: lessons from the islets of Langerhans and the thoracic aorta

Westermark, Gunilla T.; Westermark, Per

Ingår i The FEBS Journal, s. 3918-3929, 2011

• DOI för Localized amyloids important in diseases outside the brain: lessons from the islets of Langerhans and the thoracic aorta

Prion-like aggregates: infectious agents in human disease

Westermark, Gunilla T.; Westermark, Per

Ingår i Trends in Molecular Medicine, s. 501-507, 2010

• DOI för Prion-like aggregates: infectious agents in human disease

Serum amyloid A and protein AA: molecular mechanisms of a transmissible amyloidosis

Westermark, Gunilla T.; Westermark, Per

Ingår i FEBS Letters, s. 2685-2690, 2009

• DOI för Serum amyloid A and protein AA: molecular mechanisms of a transmissible amyloidosis

Amyloid deposition in transplanted human pancreatic islets: a conceivable cause of their long-term failure

Andersson, Arne; Bohman, Sara; Borg, L. A. Håkan; Paulsson, Johan F. et al.

Ingår i Experimental diabetes research, s. 562985, 2008

• DOI för Amyloid deposition in transplanted human pancreatic islets: a conceivable cause of their long-term failure

AA Amyloidosis: Pathogenesis and Targeted Therapy

Westermark, Gunilla T.; Faendrich, Marcus; Westermark, Per

Ingår i Annual Review Of Pathology, s. 321-344, ANNUAL REVIEWS, 2015

• DOI för AA Amyloidosis: Pathogenesis and Targeted Therapy

Electron tomography analysis of Islet Amyloid Poly-Peptide aggregates in drosophila melanogaster

Xie, Ling; Gu, Xiaohong; Okamoto, Kenta; Westermark, Gunilla et al.

2017

Three dimensional electron tomography characterization of islet amyloid polypeptide aggregates in drosophila melanogaster

Xie, Ling; Gu, Xiaohong; Westermark, Gunilla; Leifer, Klaus

2014

Three dimensional electron tomography characterization of islet amyloid polypeptide aggregates in drosophila melanogaster

Xie, Ling; Gu, Xiaohong; Westermark, Gunilla; Leifer, Klaus

Ingår i Electron tomography, 2014

Evaluation of Luminescent Conjugated Oligothiophenes’ Usability for Real-time Monitoring of Islet Amyloid Formation

Wang, Ye; Oskarsson, Marie E.; Nilsson, Peter; Westermark, Gunilla

Studies on Alpha-synuclein and Islet Amyloid Polypeptide Interaction in Islets

Wang, Ye; Gucek, Alenka; Bergström, Joakim; Ingelsson, Martin et al.

Proteotoxicity and Phenotypic Variability of ATTR Amyloidosis in Drosophila Melanogaster Model

Gu, Xiaohong; Westermark, Gunilla T.