Göran Akusjärvi
Professor emer. i mikrobiologi 95 vid Institutionen för medicinsk biokemi och mikrobiologi; Infektioner och Immunitet; Tanel Punga
- Mobiltelefon:
- 073-102 10 99
- E-post:
- Goran.Akusjarvi@imbim.uu.se
- Besöksadress:
- BMC
Husargatan 3
752 37 UPPSALA - Postadress:
- Box 582
751 23 UPPSALA
- Akademiska meriter:
- FD

Publikationer
Senaste publikationer
Ingår i Journal of Biological Chemistry, 2023
- DOI för The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
- Ladda ner fulltext (pdf) av The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism
Ingår i Journal of Virology, 2023
ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Ingår i Frontiers in Immunology, 2022
- DOI för ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
- Ladda ner fulltext (pdf) av ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Ixovex-1, a novel oncolytic E1B-mutated adenovirus
Ingår i Cancer Gene Therapy, s. 1628-1635, 2022
- DOI för Ixovex-1, a novel oncolytic E1B-mutated adenovirus
- Ladda ner fulltext (pdf) av Ixovex-1, a novel oncolytic E1B-mutated adenovirus
The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
Ingår i Journal of Virology, 2021
- DOI för The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
- Ladda ner fulltext (pdf) av The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
Alla publikationer
Artiklar i tidskrift
Ingår i Journal of Biological Chemistry, 2023
- DOI för The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
- Ladda ner fulltext (pdf) av The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism
Ingår i Journal of Virology, 2023
ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Ingår i Frontiers in Immunology, 2022
- DOI för ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
- Ladda ner fulltext (pdf) av ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Ixovex-1, a novel oncolytic E1B-mutated adenovirus
Ingår i Cancer Gene Therapy, s. 1628-1635, 2022
- DOI för Ixovex-1, a novel oncolytic E1B-mutated adenovirus
- Ladda ner fulltext (pdf) av Ixovex-1, a novel oncolytic E1B-mutated adenovirus
The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
Ingår i Journal of Virology, 2021
- DOI för The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
- Ladda ner fulltext (pdf) av The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation
Ingår i Frontiers in Immunology, 2019
- DOI för Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation
- Ladda ner fulltext (pdf) av Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation
Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth
Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2018
Ingår i PLOS ONE, 2017
- DOI för Expression profile of Epstein-Barr virus and human adenovirus small RNAs in tonsillar B and T lymphocytes
- Ladda ner fulltext (pdf) av Expression profile of Epstein-Barr virus and human adenovirus small RNAs in tonsillar B and T lymphocytes
An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication
Ingår i RNA, s. 1700-1711, 2017
- DOI för An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication
- Ladda ner fulltext (pdf) av An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication
Ingår i Nucleic Acids Research, s. 1731-1742, 2017
- DOI för The adenovirus L4-22K protein regulates transcription and RNA splicing via a sequence-specific single-stranded RNA binding
- Ladda ner fulltext (pdf) av The adenovirus L4-22K protein regulates transcription and RNA splicing via a sequence-specific single-stranded RNA binding
Ingår i Virology, s. 44-50, 2016
Ingår i PLOS ONE, 2016
- DOI för Distribution and Molecular Characterization of Human Adenovirus and Epstein-Barr Virus Infections in Tonsillar Lymphocytes Isolated from Patients Diagnosed with Tonsillar Diseases
- Ladda ner fulltext (pdf) av Distribution and Molecular Characterization of Human Adenovirus and Epstein-Barr Virus Infections in Tonsillar Lymphocytes Isolated from Patients Diagnosed with Tonsillar Diseases
Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils
Ingår i Journal of Visualized Experiments, 2015
Ingår i Virus Research, s. 133-140, 2015
Ingår i Virology, s. 120-128, 2015
Ingår i FEBS Letters, s. 1383-1388, 2015
Ingår i Virology, s. 25-35, 2015
Ingår i PLOS ONE, 2014
- DOI för Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance
- Ladda ner fulltext (pdf) av Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance
A mouse mammary epithelial cell line permissive for highly efficient human adenovirus growth
Ingår i Virology, s. 363-371, 2013
Ingår i Nucleic Acids Research, s. 4802-4812, 2013
- DOI för The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells
- Ladda ner fulltext (pdf) av The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells
Ingår i PLOS ONE, 2012
- DOI för Two Cellular Protein Kinases, DNA-PK and PKA, Phosphorylate the Adenoviral L4-33K Protein and Have Opposite Effects on L1 Alternative RNA Splicing
- Ladda ner fulltext (pdf) av Two Cellular Protein Kinases, DNA-PK and PKA, Phosphorylate the Adenoviral L4-33K Protein and Have Opposite Effects on L1 Alternative RNA Splicing
Ingår i Virology, s. 273-281, 2012
Using the whole-genome sequence to characterize and name human adenoviruses
Ingår i Journal of Virology, s. 5701-5702, 2011
Ingår i Genes & cancer, s. 841-851, 2011
Single molecule analysis of combinatorial splicing
Ingår i Nucleic Acids Research, 2010
Ingår i Virus Research, s. 220-228, 2010
Ingår i Cancer Research, s. 7431-7441, 2010
Adenovirus E4orf4 induces HPV-16 late L1 mRNA production
Ingår i Virology, s. 279-290, 2009
Ingår i Nucleic Acids Research, s. 6950-6959, 2009
Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 517-521, 2008
Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
Ingår i Cell Metabolism, s. 26-37, 2008
- DOI för Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
- Ladda ner fulltext (pdf) av Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
Temporal regulation of adenovirus major late alternative RNA splicing
Ingår i Frontiers in Bioscience, s. 5006-5015, 2008
Ingår i Journal of Virology, s. 10540-10549, 2007
Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing
Ingår i Experimental Cell Research, s. 2795-2809, 2007
Ingår i Journal of Virology, s. 5010-5020, 2006
L4-33K, an adenovirus-encoded alternative RNA splicing factor
Ingår i Journal of Biological Chemistry, s. 36510-36517, 2006
Ingår i Virus research, s. 16-23, 2006
Ingår i Virus Res, s. 16-23, 2006
Suppression of RNA interference by adenovirus virus-associated RNA
Ingår i Journal of Virology, s. 9556-65, 2005
Ingår i Endocrinology, s. 2406-2414, 2005
Ingår i J Biol Chem, s. 25478-84, 2005
Ingår i Journal of General Virology, s. 185-196, 2004
Ingår i Biochem J, s. 343-50, 2004
Remodelling of the host cell RNA splicing machinery during an adenovirusinfection
Ingår i Current Topics in Microbiology and Immunology, s. 253-286, 2003
Ingår i FEBS Letters, s. 214-218, 2003
Ingår i FEBS Letters, s. 214-218, 2003
Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression
Ingår i Molecular Medicine, s. 733-741, 2002
Ingår i Journal of Biological Chemistry, s. 12579-12586, 2002
Ingår i Virus Research, s. 197-206, 2002
Functional inactivation of the SR family of splicing factors during a vaccinia virus infection
Ingår i EMBO Reports, s. 1088-1093, 2002
Ingår i The Journal of Biological Chemistry, s. 12579-12586, 2002
Cisplatin induces the proapoptotic conformation of Bak in a deltaMEKK1-dependent manner
Ingår i Molecular and Cellular Biology, s. 3684-3691, 2001
Adenovirus vector designed for expression of toxic proteins
Ingår i Journal of Virology, s. 9579-9584, 2001
Ingår i EMBO Journal, s. 864-871, 2001
A novel type of splicing enhancer regulating adenovirus pre-mRNA splicing
Ingår i Molecular and Cellular Biology, s. 2317-2325, 2000
Ingår i Apoptosis (London), s. 355-367, 2000
Ingår i Cell growth & differentiation, s. 373-384, 2000
Ingår i Journal of Virology, s. 9002-9009, 2000
The adenovirus-2 E1B-55K protein interacts with a mSin3A/histone deacetylase 1 complex
Ingår i FEBS Letters, s. 248-252, 2000
Functional coexpression of serine protein kinase SRPK1 and its substrateASF/SF2 in Escherichia coli
Ingår i Nucleic Acids Research, 2000
The adenovirus-2 E1B-55K protein interacts with a mSin3A/histone deacetylase 1 complex.
Ingår i FEBS Letters, s. 248-252, 2000
Ingår i Virology, s. 313-321, 1999
A downstream splicing enhancer is essential for in vitro pre-mRNA splicing
Ingår i FEBS Letters, s. 10-14, 1999
Ingår i EMBO Journal, s. 1014-1024, 1999
Ingår i EMBO Journal, s. 1014-1024, 1999
Ingår i Journal of Virology, s. 8358-8861, 1998
AR1 is an integral part of the adenovirus-2 E1A CR3 transactivation domain
Ingår i Journal of Virology, s. 5978-5983, 1998
Regulation of adenovirus alternative RNAsplicing by dephosphorylation of SR proteins
Ingår i Nature, s. 185-187, 1998
Ingår i Journal of Virology, s. 8358-8361, 1998
Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins
Ingår i Nature, s. 185-187, 1998
Ingår i FEBS Letters, s. 111-116, 1997
Ingår i Journal of Virology, s. 3844-6851, 1996
Inhibition by SRproteins of splicing of a regulated adenovirus pre-mRNA
Ingår i Nature, s. 535-538, 1996
Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies
Ingår i Journal of Cell Biology, s. 45-56, 1995
Enhanced splicing of nonconsensus 3' splice sites late during adenovirus infection
Ingår i Journal of Virology, s. 7324-7327, 1995
Ingår i Nucleic Acids Symposium Series, s. 220-223, 1995
Artiklar, forskningsöversikt
Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs
Ingår i Viruses, 2020
- DOI för Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs
- Ladda ner fulltext (pdf) av Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs
Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections
Ingår i Viruses, 2020
- DOI för Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections
- Ladda ner fulltext (pdf) av Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections
Regulation of Human Adenovirus Alternative RNA Splicing by the Adenoviral L4-33K and L4-22K Proteins
Ingår i International Journal of Molecular Sciences, s. 2893-2912, 2015
- DOI för Regulation of Human Adenovirus Alternative RNA Splicing by the Adenoviral L4-33K and L4-22K Proteins
- Ladda ner fulltext (pdf) av Regulation of Human Adenovirus Alternative RNA Splicing by the Adenoviral L4-33K and L4-22K Proteins
Old and new functions for the adenovirus virus-associated RNAs
Ingår i Future Virology, s. 343-356, 2013
Characterization of RISC-associated adenoviral small RNAs
Ingår i Methods in molecular biology (Clifton, N.J.), s. 183-198, 2011
Kapitel i böcker, delar av antologi
Regulation of adenovirus alternative RNA splicing by PKA, DNA-PK, PP2A and SR proteins
Ingår i Virology II: Advanced Issues, iConcept Press, 2014
Ingår i Encyclopedia of Life Sciences, s. 1-8, John Wiley, 2007
In vitro methods to study RNA interference during an adenovirus infection
Ingår i Adenovirus Methods and Protocols: Volume 2: Ad Proteins, RNA Lifecycle, Host Interactions, and Phylogenetics, s. 47-61, Humana Press Inc, Totowa, NJ, 2007
Preparation of soluble extracts from adenovirus-infected cells for studies of RNA-splicing
Ingår i Adenovirus Methods and Protocols, s. 33-46, Springer, 2007
Preparation of Soluble Extracts From Adenovirus-Infected Cells for Studies of RNA Spicing
Ingår i Adenovirus Methods and Protocols, s. 33-46, Humana Press Inc, Totowa, NJ, 2007
Ingår i Encyclopedia of Life Sciences, Nature Publishing, 2002
Ingår i The Encyclopedia of Physical Science and Technology, s. 501-517, Academic Press, San Diego, 2000
Remodelling of the host cell RNA splicing machinery during an adenovirus infection
Ingår i Recent research developments in Virology, s. 621, Transworld Research Network, 1999
Preparation of splicing competent nuclear extracts from adenovirus infected cells
Ingår i Adenovirus Methods and Protocols, s. 203-216, Humana Press Inc, 1998
Ingår i Clinical Virology, ChurchillLivingstone Inc, 1997
Gene expression, regulation of
Ingår i Encyclopedia of molecular biology and Molecular Medicine, s. 364-375, VCHPublishers, New York., 1996
Gene expression, regulation of
Ingår i The Encyclopedia of Molecular Biology and Biotechnology, s. 346, VCH Publishers, New York., 1995
Regulation of adenovirus alternative RNA splicing by PKA, DNA-PK, PP2A and SR proteins