Lars Rönnblom

Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Eloranta, Maija-Leena; Nygren, Peter; Larsson, Rolf; Loskog, Angelica et al.

Ingår i Scientific Reports, 2026

• DOI för Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus
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Systemic lupus erythematosus: from an adverse event of interferon administration to a disease with new treatment options

Rönnblom, Lars

Ingår i Upsala Journal of Medical Sciences, 2025

• DOI för Systemic lupus erythematosus: from an adverse event of interferon administration to a disease with new treatment options
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Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE

Torell, Agnes; Andersson, Kerstin; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Ingår i Lupus Science and Medicine, 2025

• DOI för Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE
• Ladda ner fulltext (pdf) av Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Wiley, Mandi M.; Radziszewski, Marcin; Khatri, Bhuwan; Joachims, Michelle L. et al.

Ingår i Annals of the Rheumatic Diseases, s. 1512-1527, 2025

• DOI för Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Bianchi, Matteo; Kozyrev, Sergey V.; Notarnicola, Antonella; Sandling, Johanna K. et al.

Ingår i Arthritis & Rheumatology, s. 212-225, 2025

• DOI för Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases
• Ladda ner fulltext (pdf) av Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Eloranta, Maija-Leena; Nygren, Peter; Larsson, Rolf; Loskog, Angelica et al.

Ingår i Scientific Reports, 2026

• DOI för Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE

Torell, Agnes; Andersson, Kerstin; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Ingår i Lupus Science and Medicine, 2025

• DOI för Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE
• Ladda ner fulltext (pdf) av Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Wiley, Mandi M.; Radziszewski, Marcin; Khatri, Bhuwan; Joachims, Michelle L. et al.

Ingår i Annals of the Rheumatic Diseases, s. 1512-1527, 2025

• DOI för Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Bianchi, Matteo; Kozyrev, Sergey V.; Notarnicola, Antonella; Sandling, Johanna K. et al.

Ingår i Arthritis & Rheumatology, s. 212-225, 2025

• DOI för Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases
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Rheumatoid Arthritis Related B-Cell Changes Are Found Already in the Risk-RA Phase

de Vries, Charlotte; Huang, Wenqi; Sharma, Ravi Kumar; Wangriatisak, Kittikorn et al.

Ingår i European Journal of Immunology, 2025

• DOI för Rheumatoid Arthritis Related B-Cell Changes Are Found Already in the Risk-RA Phase
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A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile

Lindelöf, Linnea; Rantapää-Dahlqvist, Solbritt; Lundtoft, Christian; Sandling, Johanna K. et al.

Ingår i Journal of Autoimmunity, 2024

• DOI för A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile
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Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Stockfelt, Marit; Torell, Agnes; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Ingår i Rheumatology, s. 1469-1475, 2024

• DOI för Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus
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The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population

Lundtoft, Christian; Knight, Ann; Meadows, Jennifer; Karlsson, Åsa et al.

Ingår i RMD Open, 2024

• DOI för The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population
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Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy

Torell, Agnes; Stockfelt, Marit; Blennow, Kaj; Zetterberg, Henrik et al.

Ingår i Arthritis Research & Therapy, 2024

• DOI för Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy
• Ladda ner fulltext (pdf) av Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy

Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis

Turcinov, Sara; Sharma, Ravi Kumar; De Vries, Charlotte; Cîrciumaru, Alexandra et al.

Ingår i RMD Open, 2024

• DOI för Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis
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Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus

Torell, Agnes; Stockfelt, Marit; Larsson, Gunilla; Blennow, Kaj et al.

Ingår i Arthritis Research & Therapy, 2023

• DOI för Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus

Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies

Leclair, Valerie; Galindo-Feria, Angeles S.; Rothwell, Simon; Krystufkova, Olga et al.

Ingår i EBioMedicine, 2023

• DOI för Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies
• Ladda ner fulltext (pdf) av Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies

2022 EULAR points to consider for the measurement, reporting and application of IFN-I pathway activation assays in clinical research and practice

Rodriguez-Carrio, Javier; Burska, Agata; Conaghan, Philip G.; Dik, Willem A. et al.

Ingår i Annals of the Rheumatic Diseases, s. 754-762, 2023

• DOI för 2022 EULAR points to consider for the measurement, reporting and application of IFN-I pathway activation assays in clinical research and practice

Relation between HLA and copy number variation of steroid 21-hydroxylase in a Swedish cohort of patients with autoimmune Addison's disease

Lundtoft, Christian; Eriksson, Daniel; Bianchi, Matteo; Aranda-Guillen, Maribel et al.

Ingår i European Journal of Endocrinology, s. 235-241, 2023

• DOI för Relation between HLA and copy number variation of steroid 21-hydroxylase in a Swedish cohort of patients with autoimmune Addison's disease
• Ladda ner fulltext (pdf) av Relation between HLA and copy number variation of steroid 21-hydroxylase in a Swedish cohort of patients with autoimmune Addison's disease

Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis

Ekman, Diana; Sennblad, Bengt; Knight, Ann; Karlsson, Åsa et al.

Ingår i Rheumatology, s. 3213-3218, 2023

• DOI för Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis
• Ladda ner fulltext (pdf) av Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis

Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease

Yavuz, Sule; Pucholt, Pascal; Sandling, Johanna K.; Bianchi, Matteo et al.

Ingår i Lupus Science and Medicine, 2022

• DOI för Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease
• Ladda ner fulltext (pdf) av Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease

Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Lundtoft, Christian; Pucholt, Pascal; Martin, Myriam; Bianchi, Matteo et al.

Ingår i Arthritis & Rheumatology, s. 1440-1450, 2022

• DOI för Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
• Ladda ner fulltext (pdf) av Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Contribution of rare genetic variation to disease susceptibility in a large Scandinavian myositis cohort

Bianchi, Matteo; Kozyrev, Sergey V.; Notarnicola, Antonella; Hultin-Rosenberg, Lina et al.

Ingår i Arthritis & Rheumatology, s. 342-352, 2022

• DOI för Contribution of rare genetic variation to disease susceptibility in a large Scandinavian myositis cohort
• Ladda ner fulltext (pdf) av Contribution of rare genetic variation to disease susceptibility in a large Scandinavian myositis cohort

Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations

Diaz-Gallo, Lina-Marcela; Oke, Vilija; Lundström, Emeli; Elvin, Kerstin et al.

Ingår i ACR Open Rheumatology, s. 27-39, 2022

• DOI för Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations
• Ladda ner fulltext (pdf) av Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations

Genome-wide association study identifies Sjogren's risk loci with functional implications in immune and glandular cells

Khatri, Bhuwan; Tessneer, Kandice L.; Rasmussen, Astrid; Aghakhanian, Farhang et al.

Ingår i Nature Communications, 2022

• DOI för Genome-wide association study identifies Sjogren's risk loci with functional implications in immune and glandular cells
• Ladda ner fulltext (pdf) av Genome-wide association study identifies Sjogren's risk loci with functional implications in immune and glandular cells

Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Lundtoft, Christian; Sjöwall, Christopher; Rantapää‐Dahlqvist, Solbritt; Bengtsson, Anders A. et al.

Ingår i Arthritis & Rheumatology, s. 1842-1850, 2022

• DOI för Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome
• Ladda ner fulltext (pdf) av Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma

Nilsson, Magnus; Rhedin, Magdalena; Hendrickx, Ramon; Berglund, Susanne et al.

Ingår i Drug Design, Development and Therapy, s. 2901-2917, 2022

• DOI för Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma
• Ladda ner fulltext (pdf) av Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma

Five commercially-available antibodies react differentially with allelic forms of human HLA-DR beta chain

Houtman, Miranda; Dzebisashvili, Anna; Dubnovitsky, Anatoly; Kozhukh, Genadiy et al.

Ingår i Molecular Immunology, s. 106-110, 2022

• DOI för Five commercially-available antibodies react differentially with allelic forms of human HLA-DR beta chain
• Ladda ner fulltext (pdf) av Five commercially-available antibodies react differentially with allelic forms of human HLA-DR beta chain

Genetic variants at the RTP4/MASP1 locus are associated with fatigue in Scandinavian patients with primary Sjogren's syndrome

Norheim, Katrine Braekke; Imgenberg-Kreuz, Juliana; Alexsson, Andrei; Johnsen, Svein Joar Auglaend et al.

Ingår i RMD Open, 2021

• DOI för Genetic variants at the RTP4/MASP1 locus are associated with fatigue in Scandinavian patients with primary Sjogren's syndrome
• Ladda ner fulltext (pdf) av Genetic variants at the RTP4/MASP1 locus are associated with fatigue in Scandinavian patients with primary Sjogren's syndrome

Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus

Enocsson, Helena; Wetterö, Jonas; Eloranta, Maija-Leena; Gullstrand, Birgitta et al.

Ingår i Frontiers in Immunology, 2021

• DOI för Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus
• Ladda ner fulltext (pdf) av Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus

C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

Enocsson, Helena; Gullstrand, Birgitta; Eloranta, Maija-Leena; Wetterö, Jonas et al.

Ingår i Frontiers in Immunology, 2021

• DOI för C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205
• Ladda ner fulltext (pdf) av C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

Toll-like receptors revisited: a possible role for TLR1 in lupus nephritis

Yavuz, Sule; Bianchi, Matteo; Kozyrev, Sergey; Bolin, Karin et al.

Ingår i Annals of the Rheumatic Diseases, s. 404-406, 2021

• DOI för Toll-like receptors revisited: a possible role for TLR1 in lupus nephritis
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Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome

Thorlacius, Guðný Ella; Hultin-Rosenberg, Lina; Sandling, Johanna K.; Bianchi, Matteo et al.

Ingår i Rheumatology, s. 837-848, 2021

• DOI för Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome
• Ladda ner fulltext (pdf) av Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome

Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

Sandling, Johanna K.; Pucholt, Pascal; Hultin-Rosenberg, Lina; Farias, Fabiana H. G. et al.

Ingår i Annals of the Rheumatic Diseases, s. 109-117, 2021

• DOI för Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
• Ladda ner fulltext (pdf) av Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

Reid, Sarah; Hagberg, Niklas; Sandling, Johanna K.; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 1183-1189, 2021

• DOI för Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

De novo lupus nephritis during treatment with belimumab

Parodis, Ioannis; Vital, Edward M.; Hassan, Sabih-Ul; Jönsen, Andreas et al.

Ingår i Rheumatology, s. 4348-4354, 2021

• DOI för De novo lupus nephritis during treatment with belimumab
• Ladda ner fulltext (pdf) av De novo lupus nephritis during treatment with belimumab

DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Norheim, Katrine Braekke; Johnsen, Svein Joar Auglaend et al.

Ingår i Frontiers in Immunology, 2021

• DOI för DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome
• Ladda ner fulltext (pdf) av DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome

Variants in BANK1 are associated with lupus nephritis of European ancestry.

Bolin, Karin; Imgenberg-Kreuz, Juliana; Leonard, Dag; Sandling, Johanna K. et al.

Ingår i Genes and Immunity, s. 194-202, 2021

• DOI för Variants in BANK1 are associated with lupus nephritis of European ancestry.
• Ladda ner fulltext (pdf) av Variants in BANK1 are associated with lupus nephritis of European ancestry.

Contributions of de novo variants to systemic lupus erythematosus

Carlsson Almlöf, Jonas; Nystedt, Sara; Mechtidou, Aikaterini; Leonard, Dag et al.

Ingår i European Journal of Human Genetics, s. 184-193, 2021

• DOI för Contributions of de novo variants to systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Contributions of de novo variants to systemic lupus erythematosus

NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE

Georgakis, Spiros; Gkirtzimanaki, Katerina; Papadaki, Garyfalia; Gakiopoulou, Hariklia et al.

Ingår i JCI Insight, 2021

• DOI för NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE
• Ladda ner fulltext (pdf) av NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE

Association of Protective HLA-A With HLA-B∗27 Positive Ankylosing Spondylitis

Nordin, Jessika; Pettersson, Mats; Hultin Rosenberg, Lina; Mathioudaki, Argyri et al.

Ingår i Frontiers in Genetics, 2021

• DOI för Association of Protective HLA-A With HLA-B∗27 Positive Ankylosing Spondylitis
• Ladda ner fulltext (pdf) av Association of Protective HLA-A With HLA-B∗27 Positive Ankylosing Spondylitis

Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA

Dahlqvist, Johanna; Ekman, Diana; Sennblad, Bengt; Kozyrev, Sergey V. et al.

Ingår i Rheumatology, s. 3461-3470, 2021

• DOI för Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
• Ladda ner fulltext (pdf) av Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA

Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19

Gaziano, Liam; Giambartolomei, Claudia; Pereira, Alexandre C.; Gaulton, Anna et al.

Ingår i Nature Medicine, 2021

• DOI för Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19

Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients

Houtman, Miranda; Hesselberg, Espen; Rönnblom, Lars; Klareskog, Lars et al.

Ingår i Frontiers in Immunology, 2021

• DOI för Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients
• Ladda ner fulltext (pdf) av Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients

Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study

Yavuz, Sule; Cansu, Dondu U.; Nikolopoulos, Dionysis; Crisafulli, Francesca et al.

Ingår i Seminars in Arthritis & Rheumatism, s. 1387-1393, 2020

• DOI för Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study

Immunogenetics in systemic lupus erythematosus: Transitioning from genetic associations to cellular effects

Hagberg, Niklas; Lundtoft, Christian; Rönnblom, Lars

Ingår i Scandinavian Journal of Immunology, 2020

• DOI för Immunogenetics in systemic lupus erythematosus: Transitioning from genetic associations to cellular effects
• Ladda ner fulltext (pdf) av Immunogenetics in systemic lupus erythematosus: Transitioning from genetic associations to cellular effects

High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Morris, David et al.

Ingår i Annals of the Rheumatic Diseases, s. 363-369, 2020

• DOI för High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

Learning from similarities between vaccine responses and SLE

Wahren-Herlenius, Marie; Rönnblom, Lars

Ingår i Nature Reviews Rheumatology, s. 355-356, 2020

• DOI för Learning from similarities between vaccine responses and SLE

Proinflammatory Histidyl-Transfer RNA Synthetase-Specific CD4+T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies

Galindo-Feria, Angeles S.; Albrecht, Inka; Fernandes-Cerqueira, Catia; Notarnicola, Antonella et al.

Ingår i Arthritis & Rheumatology, s. 179-191, 2020

• DOI för Proinflammatory Histidyl-Transfer RNA Synthetase-Specific CD4+T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies

Biomarkers: to be or not to be

Yavuz, Sule; Rönnblom, Lars

Ingår i Annals of the Rheumatic Diseases, 2020

• DOI för Biomarkers: to be or not to be

Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists

Berggren, Olof; Pucholt, Pascal; Amcoff, Cane; Rönnblom, Lars et al.

Ingår i Scandinavian Journal of Immunology, 2020

• DOI för Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists
• Ladda ner fulltext (pdf) av Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists

The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells

Hjorton, Karin; Hagberg, Niklas; Pucholt, Pascal; Eloranta, Maija-Leena et al.

Ingår i Arthritis Research & Therapy, 2020

• DOI för The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells
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Population-based study of patients with primary Sjögren's syndrome and lymphoma: lymphoma subtypes, clinical characteristics, and gender differences

Vasaitis, Lilian; Nordmark, Gunnel; Theander, E; Backlin, Carin et al.

Ingår i Scandinavian Journal of Rheumatology, s. 225-232, 2020

• DOI för Population-based study of patients with primary Sjögren's syndrome and lymphoma: lymphoma subtypes, clinical characteristics, and gender differences

Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero

Hedlund, Malin; Thorlacius, Gudny Ella; Ivanchenko, Margarita; Ottosson, Vijole et al.

Ingår i RMD Open, 2020

• DOI för Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
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NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus

Linge, Petrus; Arve, Sabine; Olsson, Lina M.; Leonard, Dag et al.

Ingår i Annals of the Rheumatic Diseases, s. 254-261, 2020

• DOI för NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus

Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS: Evaluation of whole blood, plasma and serum as sample matrices

Carlsson, Henrik; Hjorton, Karin; Abujrais, Sandy; Rönnblom, Lars et al.

Ingår i Arthritis Research & Therapy, 2020

• DOI för Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS: Evaluation of whole blood, plasma and serum as sample matrices
• Ladda ner fulltext (pdf) av Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS: Evaluation of whole blood, plasma and serum as sample matrices

Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling

Lundtoft, Christian; Pucholt, Pascal; Imgenberg-Kreuz, Juliana; Carlsson Almlöf, Jonas et al.

Ingår i PLOS Genetics, 2020

• DOI för Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling
• Ladda ner fulltext (pdf) av Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling

Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis

Gerstner, Christina; Turcinov, Sara; Hensvold, Aase H.; Chemin, Karine et al.

Ingår i BMC Immunology, 2020

• DOI för Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis
• Ladda ner fulltext (pdf) av Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis

Comparison of patients with and without pre-existing lymphoma at diagnosis of primary Sjögren's syndrome

Vasaitis, Lilian; Nordmark, Gunnel; Theander, E; Backlin, Carin et al.

Ingår i Scandinavian Journal of Rheumatology, s. 207-212, 2019

• DOI för Comparison of patients with and without pre-existing lymphoma at diagnosis of primary Sjögren's syndrome
• Ladda ner fulltext (pdf) av Comparison of patients with and without pre-existing lymphoma at diagnosis of primary Sjögren's syndrome

Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases

Weissenberg, Sarah Y.; Szelinski, Franziska; Schrezenmeier, Eva; Stefanski, Ana-Luisa et al.

Ingår i Frontiers in Immunology, 2019

• DOI för Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases
• Ladda ner fulltext (pdf) av Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Odqvist, Lina; Jevnikar, Zala; Riise, Rebecca; Oberg, Lisa et al.

Ingår i Annals of the Rheumatic Diseases, s. 1363-1370, 2019

• DOI för Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-a levels and high serum interferogenic activity

Bolin, Karin; Eloranta, Maija-Leena; Kozyrev, Sergey V.; Dahlqvist, Johanna et al.

Ingår i Rheumatology, s. 918-919, 2019

• DOI för A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-a levels and high serum interferogenic activity

Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus

Almlöf, Jonas Carlsson; Nystedt, Sara; Leonard, Dag; Eloranta, Maija-Leena et al.

Ingår i Human Genetics, s. 141-150, 2019

• DOI för Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
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Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjogren's Syndrome

Imgenberg-Kreuz, Juliana; Carlsson Almlöf, Jonas; Leonard, Dag; Sjöwall, Christopher et al.

Ingår i Frontiers in Immunology, 2019

• DOI för Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjogren's Syndrome
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Interferon-α enhances the IL-12-induced STAT4 activation selectively in carriers of the STAT4 SLE risk allele rs7574865[T]

Hagberg, Niklas; Rönnblom, Lars

Ingår i Annals of the Rheumatic Diseases, s. 429-431, 2019

• DOI för Interferon-α enhances the IL-12-induced STAT4 activation selectively in carriers of the STAT4 SLE risk allele rs7574865[T]
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Sex differences in clinical presentation of systemic lupus erythematosus

Ramírez Sepúlveda, Jorge I; Bolin, Karin; Mofors, Johannes; Leonard, Dag et al.

Ingår i Biology of Sex Differences, 2019

• DOI för Sex differences in clinical presentation of systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Sex differences in clinical presentation of systemic lupus erythematosus

Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.

Idborg, Helena; Zandian, Arash; Ossipova, Elena; Wigren, Edvard et al.

Ingår i Frontiers in Immunology, 2019

• DOI för Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.
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A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

Farias, Fabiana H. G.; Dahlqvist, Johanna; Kozyrev, Sergey V.; Leonard, Dag et al.

Ingår i European Journal of Human Genetics, s. 432-441, 2019

• DOI för A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
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Exploring rare and low-frequency variants in the Saguenay-Lac-Saint-Jean population identified genes associated with asthma and allergy traits

Morin, Andreanne; Madore, Anne-Marie; Kwan, Tony; Ban, Maria et al.

Ingår i European Journal of Human Genetics, s. 90-101, 2019

• DOI för Exploring rare and low-frequency variants in the Saguenay-Lac-Saint-Jean population identified genes associated with asthma and allergy traits
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Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements

Allum, Fiona; Hedman, Asa K.; Shaol, Xiaojian; Cheung, Warren A. et al.

Ingår i Nature Communications, 2019

• DOI för Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements
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IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis

Lindahl, Hannes; Guerreiro-Cacais, Andre O.; Bedri, Sahl Khalid; Linnerbauer, Mathias et al.

Ingår i Journal of Immunology, s. 888-898, 2019

• DOI för IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis

EOMES-positive CD4+ T cells are increased in PTPN22 (1858T) risk allele carriers.

Chemin, Karine; Ramsköld, Daniel; Diaz-Gallo, Lina-Marcela; Herrath, Jessica et al.

Ingår i European Journal of Immunology, s. 655-669, 2018

• DOI för EOMES-positive CD4+ T cells are increased in PTPN22 (1858T) risk allele carriers.

The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

Hagberg, Niklas; Joelsson, Martin; Leonard, Dag; Reid, Sarah et al.

Ingår i Annals of the Rheumatic Diseases, s. 1070-1077, 2018

• DOI för The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE
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DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Leonard, Dag; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 736-743, 2018

• DOI för DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
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Transcription profiling of peripheral B cells in antibody-positive primary Sjogren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Bjork, A.; Nordlund, J. et al.

Ingår i Scandinavian Journal of Immunology, 2018

• DOI för Transcription profiling of peripheral B cells in antibody-positive primary Sjogren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature
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T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus

Houtman, Miranda; Shchetynsky, Klementy; Chemin, Karine; Hensvold, Aase Haj et al.

Ingår i Journal of Autoimmunity, s. 28-38, 2018

• DOI för T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus
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Cytokine production by activated plasmacytoid dendritic cells and NK cells is suppressed by an IRAK4 inhibitor

Hjorton, Karin; Hagberg, Niklas; Israelsson, E.; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 1268-1269, 2018

• DOI för Cytokine production by activated plasmacytoid dendritic cells and NK cells is suppressed by an IRAK4 inhibitor

Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

Leonard, Dag; Svenungsson, Elisabet; Dahlqvist, Johanna; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 1063-1069, 2018

• DOI för Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
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Interleukin-22 and associated genes are targets of microRNAs dysregulated

Tarn, Jessica R.; Nordmark, Gunnel; Gillespie, Colin; Al-Ali, Shereen et al.

Ingår i Clinical and Experimental Rheumatology, 2018

The value of type i interferon signature to stratify patients

Rönnblom, Lars

Ingår i Annals of the Rheumatic Diseases, s. 46-46, 2018

• DOI för The value of type i interferon signature to stratify patients

Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor

Hjorton, Karin; Hagberg, Niklas; Israelsson, Elisabeth; Jinton, Lisa et al.

Ingår i Arthritis Research & Therapy, 2018

• DOI för Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor
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Functional characterization of the Sjögren's syndrome-associated locus DDX6-CXCR5

Khanam, Sharmily; Joachims, Michelle L.; Means, Nicholas; Adrianto, Indra et al.

Ingår i Clinical and Experimental Rheumatology, 2018

Genetic basis and clinical evidence for two variants of primary Sjögren's syndrome with distinct outcomes

Thorlacius, Gudny Ella; Hultin-Rosenberg, Lina; Sandling, Johanna K.; Imgenberg-Kreuz, Juliana et al.

Ingår i Clinical and Experimental Rheumatology, 2018

Shared and unique patterns of DNA methylation in primary Sjogren's syndrome and systemic lupus erythematosus

Imgenberg-Kreuz, Juliana; Leonard, Dag; Carlsson Almlöf, Jonas; Rantapaa-Dahlqvist, S. et al.

Ingår i Scandinavian Journal of Rheumatology, s. 3-3, 2018

Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden

Eriksson, Daniel; Bianchi, Matteo; Landegren, Nils; Dalin, Frida et al.

Ingår i Scientific Reports, 2018

• DOI för Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden
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ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

Bremer, Hanna D.; Landegren, Nils; Sjöberg, Ronald; Hallgren, Åsa et al.

Ingår i Scientific Reports, 2018

• DOI för ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
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Memory T cells specific to citrullinated alpha-enolase are enriched in the rheumatic joint

Pieper, Jennifer; Dubnovitsky, Anatoly; Gerstner, Christina; James, Eddie A. et al.

Ingår i Journal of Autoimmunity, s. 47-56, 2018

• DOI för Memory T cells specific to citrullinated alpha-enolase are enriched in the rheumatic joint

Treatment-Associated DNA Methylation Patterns in Systemic Lupus Erythematosus

Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Leonard, Dag; Nordmark, Gunnel et al.

Ingår i Arthritis & Rheumatology, 2017

Type I Interferon System In Autoimmunity

Rönnblom, Lars

Ingår i Annals of the Rheumatic Diseases, s. 11-11, 2017

• DOI för Type I Interferon System In Autoimmunity

High Genetic Risk Score Is Associated with Increased Organ Damage in SLE

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Sandling, Johanna K. et al.

Ingår i Arthritis & Rheumatology, 2017

Difference in Clinical Presentation between Female and Male Patients with Primary Sjogren's Syndrome at Diagnosis and in Long-Term Follow-up

Ramirez, Jorge; Kvarnstrom, Marika; Brauner, Susanna; Baldini, Chiara et al.

Ingår i Arthritis & Rheumatology, 2017

Type I IFN System Activation In Newborns Exposed To ANTI-RO/SSA Autoantibodies In Utero

Wahren, M.; Hedlund, M.; Thorlacius, G. E.; Ivanchenko, M. et al.

Ingår i Annals of the Rheumatic Diseases, s. 182-182, 2017

• DOI för Type I IFN System Activation In Newborns Exposed To ANTI-RO/SSA Autoantibodies In Utero

Genetic Determinants of Fatigue in Primary Sjogren's Syndrome: a Genome Wide Association Study

Norheim, Katrine; Alexsson, Andrei; Imgenberg-Kreuz, Juliana; Brun, Johan Gorgas et al.

Ingår i Arthritis & Rheumatology, 2017

Novel risk genes for systemic lupus erythematosus predicted by random forest classification

Carlsson Almlöf, Jonas; Alexsson, Andrei; Imgenberg-Kreuz, Juliana; Sylwan, Lina et al.

Ingår i Scientific Reports, 2017

• DOI för Novel risk genes for systemic lupus erythematosus predicted by random forest classification
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SLE Comprises Four Immune-Phenotypes, Which Differ Regarding HLA-DRB1 and Clinical Associations

Gallo, Lina Marcela Diaz; Lundstrom, Emeli; Oke, Vilija; Elvin, Kerstin et al.

Ingår i Arthritis & Rheumatology, 2017

Interferon-α coincides with suppressed levels of pentraxin-3 (PTX3) in systemic lupus erythematosus and regulates leucocyte PTX3 in vitro

Wirestam, Lina; Enocsson, Helena; Skogh, Thomas; Eloranta, Maija-Leena et al.

Ingår i Clinical and Experimental Immunology, s. 83-91, 2017

• DOI för Interferon-α coincides with suppressed levels of pentraxin-3 (PTX3) in systemic lupus erythematosus and regulates leucocyte PTX3 in vitro

A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus

Olsson, Lina M.; Johansson, Asa C.; Gullstrand, Birgitta; Jonsen, Andreas et al.

Ingår i Annals of the Rheumatic Diseases, s. 1607-1613, 2017

• DOI för A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus

Role of interferons in SLE

Bengtsson, Anders A.; Rönnblom, Lars

Ingår i Baillière's Best Practice & Research, s. 415-428, 2017

• DOI för Role of interferons in SLE

Type I IFN System Activation In Newborns Exposed To Anti-Ro/Ssa Autoantibodies In Utero

Hedlund, Malin; Thorlacius, Gudny Ella; Ivanchenko, Margarita; Kyriakidis, Nikolaos et al.

Ingår i Annals of the Rheumatic Diseases, 2017

• DOI för Type I IFN System Activation In Newborns Exposed To Anti-Ro/Ssa Autoantibodies In Utero

Expression Patterns of Interferon Induced Genes in Newborns Exposed to Ro/SSA Autoantibodies in Utero

Thorlacius, Gudny Ella; Hedlund, Malin; Ivanchenko, Margarita; Ottosson, Vijole et al.

Ingår i Arthritis & Rheumatology, 2017

Long-term follow-up in primary Sjögren's syndrome reveals differences in clinical presentation between female and male patients

Sepulveda, Jorge I. Ramirez; Kvarnstrom, Marika; Eriksson, Per; Mandl, Thomas et al.

Ingår i Biology of Sex Differences, 2017

• DOI för Long-term follow-up in primary Sjögren's syndrome reveals differences in clinical presentation between female and male patients
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Transancestral mapping and genetic load in systemic lupus erythematosus

Langefeld, Carl D.; Ainsworth, Hannah C.; Graham, Deborah S. Cunninghame; Kelly, Jennifer A. et al.

Ingår i Nature Communications, 2017

• DOI för Transancestral mapping and genetic load in systemic lupus erythematosus
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Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

Li, He; Reksten, Tove Ragna; Ice, John A.; Kelly, Jennifer A. et al.

Ingår i PLOS Genetics, 2017

• DOI för Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons
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Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype

Berggren, Olof; Hagberg, Niklas; Alexsson, Andrei; Weber, Gert et al.

Ingår i PLOS ONE, 2017

• DOI för Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype
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Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1

Smith-Anttila, Casey J. A.; Bensing, Sophie; Alimohammadi, Mohammad; Dalin, Frida et al.

Ingår i Autoimmunity, s. 223-231, 2017

• DOI för Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1

Identification of a novel pro-inflammatory T cell epitope from his-tRNA-synthetase associated with interstitial lung disease in anti-Jo-1 positive patients

Galindo-Feria, Angeles Shunashy; Albrecht, Inka; Notarnicola, Antonella; Dastmalchi, Maryam et al.

Ingår i Scandinavian Journal of Immunology, s. 317-317, 2017

A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis

Chemin, Karine; Pollastro, Sabrina; James, Eddie; Ge, Changrong et al.

Ingår i Arthritis & Rheumatology, s. 1124-1135, 2016

• DOI för A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis

Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 1728-1734, 2016

• DOI för Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Ingår i Annals of the Rheumatic Diseases, s. 2029-2036, 2016

• DOI för Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes
• Ladda ner fulltext (pdf) av Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.

Folkersen, Lasse; Brynedal, Boel; Diaz-Gallo, Lina Marcela; Ramsköld, Daniel et al.

Ingår i Molecular Medicine, s. 322-328, 2016

• DOI för Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.
• Ladda ner fulltext (pdf) av Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.

The effect of PTPN22 Gene Variant R620W on the Type I Interferon Production Stimulated by Different TLR7 Agonists: Comment on Article by Wang et al (pages 2403-2414)

Berggren, Olof; Rönnblom, Lars; Eloranta, Maija-Leena

Ingår i Arthritis & Rheumatology, s. 1045-1045, 2016

• DOI för The effect of PTPN22 Gene Variant R620W on the Type I Interferon Production Stimulated by Different TLR7 Agonists: Comment on Article by Wang et al (pages 2403-2414)

Targeting The Type I Interferon System In SLE

Rönnblom, Lars

Ingår i Clinical and Experimental Rheumatology, 2016

Identification of Sjögren's Syndrome Risk Loci near TNFAIP3 and PRDM1

Lessard, C.; Li, H.; Ice, J. A.; Adrianto, I. et al.

Ingår i Annals of the Rheumatic Diseases, s. 664-664, 2016

• DOI för Identification of Sjögren's Syndrome Risk Loci near TNFAIP3 and PRDM1

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

Morris, David L; Sheng, Yujun; Zhang, Yan; Wang, Yong-Fei et al.

Ingår i Nature Genetics, 2016

• DOI för Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

The importance of the type I interferon system in autoimmunity

Rönnblom, Lars

Ingår i Clinical and Experimental Rheumatology, 2016

Cause and consequences of the activated type I interferon system in SLE

Eloranta, Maija-Leena; Rönnblom, Lars

Ingår i Journal of Molecular Medicine, s. 1103-1110, 2016

• DOI för Cause and consequences of the activated type I interferon system in SLE
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Activated Plasmacytoid Dendritic Cells (PDCS) Alter The Composition of The Blood B Cell Subsets

Berggren, Olof; Rönnblom, Lars; Eloranta, Maija-Leena

Ingår i Annals of the Rheumatic Diseases, s. 179-179, 2016

• DOI för Activated Plasmacytoid Dendritic Cells (PDCS) Alter The Composition of The Blood B Cell Subsets

The Effect of Hydroxychloroquine and IRAK4 Inhibition on The IFN-A and TNF-A Production Induced by Sle Related Immune Complexes

Hjorton, Karin; Hagberg, Niklas; Berggren, Olof; Mo, J. et al.

Ingår i Annals of the Rheumatic Diseases, s. 277-277, 2016

• DOI för The Effect of Hydroxychloroquine and IRAK4 Inhibition on The IFN-A and TNF-A Production Induced by Sle Related Immune Complexes

The Interferon Pathway in Sle: from Immunology To New Insights and New Treatment

Rönnblom, Lars

Ingår i Annals of the Rheumatic Diseases, s. 40-41, 2016

• DOI för The Interferon Pathway in Sle: from Immunology To New Insights and New Treatment

Case definitions in Swedish register data to identify systemic lupus erythematosus

Arkema, Elizabeth V; Jönsen, Andreas; Rönnblom, Lars; Svenungsson, Elisabet et al.

Ingår i BMJ Open, 2016

• DOI för Case definitions in Swedish register data to identify systemic lupus erythematosus
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Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Cavalli, Marco; Pan, Gang; Nord, Helena; Wallerman, Ola et al.

Ingår i Human Genetics, s. 485-497, 2016

• DOI för Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression
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Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells

Morin, Andreanne; Kwan, Tony; Ge, Bing; Letourneau, Louis et al.

Ingår i BMC Medical Genomics, 2016

• DOI för Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells
• Ladda ner fulltext (pdf) av Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells

DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands

Wahlberg, Per; Lundmark, Anders; Nordlund, Jessica; Busche, Stephan et al.

Ingår i Epigenomics, s. 1367-1387, 2016

• DOI för DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands
• Ladda ner fulltext (pdf) av DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis

Gerstner, Christina; Dubnovitsky, Anatoly; Sandin, Charlotta; Kozhukh, Genadiy et al.

Ingår i Frontiers in Immunology, 2016

• DOI för Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis
• Ladda ner fulltext (pdf) av Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis

Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease

Eriksson, D.; Bianchi, Matteo; Landegren, Nils; Nordin, Jessika et al.

Ingår i Journal of Internal Medicine, s. 595-608, 2016

• DOI för Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease
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Epigenome data release: a participant-centered approach to privacy protection

Dyke, Stephanie O M; Cheung, Warren A; Joly, Yann; Ammerpohl, Ole et al.

Ingår i Genome Biology, 2015

• DOI för Epigenome data release: a participant-centered approach to privacy protection
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Hypomethylation in Enhancer and Promoter Regions of Interferon Regulated Genes in Multiple Tissues Is Associated with Primary Sjogren's Syndrome

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Ingår i Arthritis & Rheumatology, 2015

• DOI för Hypomethylation in Enhancer and Promoter Regions of Interferon Regulated Genes in Multiple Tissues Is Associated with Primary Sjogren's Syndrome

A Novel HLA-DRB1*10:01 Restricted T Cell Epitope from Citrullinated Type II Collagen Relevant for Rheumatoid Arthritis

Chemin, Karine; Pollastro, Sabrina; James, Eddie; Ge, Changrong et al.

Ingår i Arthritis & Rheumatology, 2015

• DOI för A Novel HLA-DRB1*10:01 Restricted T Cell Epitope from Citrullinated Type II Collagen Relevant for Rheumatoid Arthritis

Identification of Novel Sjogren's Syndrome Risk Loci in the Regions of TNFAIP3 and PRDM1

Lessard, Christopher J.; Li, He; Ice, John; Adrianto, Indra et al.

Ingår i Arthritis & Rheumatology, 2015

• DOI för Identification of Novel Sjogren's Syndrome Risk Loci in the Regions of TNFAIP3 and PRDM1

Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants

Allum, Fiona; Shao, Xiaojian; Guénard, Frédéric; Simon, Marie-Michelle et al.

Ingår i Nature Communications, 2015

• DOI för Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants
• Ladda ner fulltext (pdf) av Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants

Functional Anti-CD94/NKG2A and Anti-CD94/NKG2C Autoantibodies in Patients With Systemic Lupus Erythematosus

Hagberg, Niklas; Theorell, Jakob; Hjorton, Karin; Spee, Pieter et al.

Ingår i ARTHRITIS & RHEUMATOLOGY, s. 1000-1011, 2015

• DOI för Functional Anti-CD94/NKG2A and Anti-CD94/NKG2C Autoantibodies in Patients With Systemic Lupus Erythematosus

Early B Cell Factor 1 is Associated to Clinical Manifestations in Primary Sjogren's Syndrome and SLE

Bolin, Karin; Leonard, Dag; Gunnarsson, I.; Sjowall, C. et al.

Ingår i Scandinavian Journal of Immunology, s. 416-416, 2015

Genome-Wide Analysis of DNA Methylation Profiles in Multiple Tissues in Primary Sjogren's Syndrome

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Carlsson Almlöf, Jonas; Omdal, Roald et al.

Ingår i Scandinavian Journal of Immunology, s. 412-412, 2015

IFN-α production by plasmacytoid dendritic cell associations with polymorphisms in gene loci related to autoimmune and inflammatory diseases

Berggren, Olof; Alexsson, Andrei; Morris, David; Tandre, Karolina et al.

Ingår i Human Molecular Genetics, s. 3571-3581, 2015

• DOI för IFN-α production by plasmacytoid dendritic cell associations with polymorphisms in gene loci related to autoimmune and inflammatory diseases

Genome-wide analysis of DNA methylation in systemic lupus erythematosus

Sandling, Johanna K.; Imgenberg-Kreuz, Juliana; Carlsson Almlöf, Jonas; Nordmark, Gunnel et al.

Ingår i Clinical and Experimental Rheumatology, 2015

Immune complex mediated activation of plasmacytoid dendritic cells in SLE

Rönnblom, Lars

Ingår i Clinical and Experimental Rheumatology, 2015

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

Bentham, James; Morris, David L; Cunninghame Graham, Deborah S; Pinder, Christopher L et al.

Ingår i Nature Genetics, s. 1457-1464, 2015

• DOI för Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

An epigenome-wide association study of total serum immunoglobulin E concentration

Liang, Liming; Willis-Owen, Saffron A. G.; Laprise, Catherine; Wong, Kenny C. C. et al.

Ingår i Nature, s. 670-U188, 2015

• DOI för An epigenome-wide association study of total serum immunoglobulin E concentration

Recurrent Pyoderma Gangrenosum and Cystic Acne Associated with Leucocyte Adhesion Deficiency due to Novel Mutations in ITGB2: Successful Treatment with Infliximab and Adalimumab

Vahlquist, Anders; Håkansson, Lena Douhan; Rönnblom, Lars; Karawajczyk, Malgorzata et al.

Ingår i Acta Dermato-Venereologica, s. 349-351, 2015

• DOI för Recurrent Pyoderma Gangrenosum and Cystic Acne Associated with Leucocyte Adhesion Deficiency due to Novel Mutations in ITGB2: Successful Treatment with Infliximab and Adalimumab

Serum C-reactive protein (CRP) associates with lupus disease activity in the absence of measurable interferon alpha and a CRP gene variant

Enocsson, Helena; Sjöwall, Christopher; Kastbom, Alf; Skogh, Thomas et al.

Ingår i Arthritis & rheumatology, s. 1568-1573, 2014

• DOI för Serum C-reactive protein (CRP) associates with lupus disease activity in the absence of measurable interferon alpha and a CRP gene variant

Effect of single-nucleotide polymorphisms on type I interferon production by plasmacytoid dendritic cells stimulated with SLE-associated immune complexes

Berggren, Olof; Alexsson, Andrei; Tandre, Karolina; Syvanen, A-C et al.

Ingår i Scandinavian Journal of Rheumatology, s. 92-92, 2014

Activated T cells enhance interferon-alpha production by plasmacytoid dendritic cells stimulated by RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Scandinavian Journal of Rheumatology, s. 88-89, 2014

Utility of Swedish Register Data in Classifying Systemic Lupus

Arkema, E.; Jonsen, A.; Rönnblom, Lars; Sjowall, C. et al.

Ingår i Annals of the Rheumatic Diseases, s. 444-444, 2014

• DOI för Utility of Swedish Register Data in Classifying Systemic Lupus

High-Throughput Sequencing of 219 Candidate Genes for Identification of SLE-Associated Risk Variants

Farias, Fabiana; Wilbe, Maria; Dahlqvist, Johanna; Leonard, Dag et al.

Ingår i Arthritis & Rheumatology, 2014

Genome-Wide DNA Methylation Analysis of CD19+B Cells in Primary Sjogren's Syndrome

Nordmark, Gunnel; Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Ingår i Arthritis & Rheumatology, 2014

Activated SLE-T Cells Enhance the Interferon-Alpha Production By Plasmacytoid Dendritic Cells Stimulated By RNA-IC

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Arthritis & Rheumatology, 2014

Systemic Lupus Prevalence in Sweden in 2010: What do national registers say?

Simard, Julia F; Sjöwall, Christopher; Rönnblom, Lars; Jönsen, Andreas et al.

Ingår i Arthritis Care and Research, s. 1710-1717, 2014

• DOI för Systemic Lupus Prevalence in Sweden in 2010: What do national registers say?

Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs

Adoue, Veronique; Schiavi, Alicia; Light, Nicholas; Carlsson Almlöf, Jonas et al.

Ingår i Molecular Systems Biology, s. 754, 2014

• DOI för Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs
• Ladda ner fulltext (pdf) av Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12

Kilarski, Laura L.; Achterberg, Sefanja; Devan, William J.; Traylor, Matthew et al.

Ingår i Neurology, s. 678-685, 2014

• DOI för Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12

Anti-NKG2A autoantibodies in a patient with systemic lupus erythematosus

Hagberg, Niklas; Theorell, Jakob; Eloranta, Maija-Leena; Pascal, Veronique et al.

Ingår i Rheumatology, s. 1818-1823, 2013

• DOI för Anti-NKG2A autoantibodies in a patient with systemic lupus erythematosus

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

Lessard, Christopher J; Li, He; Adrianto, Indra; Ice, John A et al.

Ingår i Nature Genetics, s. 1284-1292, 2013

• DOI för Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

No association of primary Sjogren's syndrome with Fc gamma receptor gene variants

Haldorsen, K; Appel, S; Le Hellard, S; Bruland, O et al.

Ingår i Genes and Immunity, s. 234-237, 2013

• DOI för No association of primary Sjogren's syndrome with Fc gamma receptor gene variants
• Ladda ner fulltext (pdf) av No association of primary Sjogren's syndrome with Fc gamma receptor gene variants

Brief Report: Interferon-α Induction and Detection of Anti-Ro, Anti-La, Anti-Sm, and Anti-RNP Autoantibodies by Autoantigen Microarray Analysis in Juvenile Dermatomyositis

Balboni, Imelda; Niewold, Timothy B; Morgan, Gabrielle; Limb, Cindy et al.

Ingår i Arthritis and Rheumatism, s. 2424-2429, 2013

• DOI för Brief Report: Interferon-α Induction and Detection of Anti-Ro, Anti-La, Anti-Sm, and Anti-RNP Autoantibodies by Autoantigen Microarray Analysis in Juvenile Dermatomyositis

Dual role of CpG-stimulated B cells in the regulation of dendritic cells: comment on the article by Berggren et al Reply

Eloranta, Maija-Leena; Rönnblom, Lars

Ingår i Arthritis and Rheumatism, s. 2216, 2013

• DOI för Dual role of CpG-stimulated B cells in the regulation of dendritic cells: comment on the article by Berggren et al Reply

Clinical manifestations and anti-phospholipid antibodies in 712 patients with systemic lupus erythematosus: evaluation of two diagnostic assays

Vikerfors, Anna; Johansson, Anna-Britta; Gustafsson, Johanna T; Jönsen, Andreas et al.

Ingår i Rheumatology, s. 345-353, 2013

• DOI för Clinical manifestations and anti-phospholipid antibodies in 712 patients with systemic lupus erythematosus: evaluation of two diagnostic assays

RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE

Stone, R. C.; Du, P.; Feng, D.; Dhawan, K. et al.

Ingår i PLOS ONE, s. 54487, 2013

• DOI för RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE
• Ladda ner fulltext (pdf) av RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE

Two rare disease-associated tyk2 variants are catalytically impaired but signaling competent

Li, Zhi; Gakovic, Milica; Ragimbeau, Josiane; Eloranta, Maija-Leena et al.

Ingår i Journal of Immunology, s. 2335-2344, 2013

• DOI för Two rare disease-associated tyk2 variants are catalytically impaired but signaling competent

Disease Mechanisms in RheumatologyTools and Pathways: Plasmacytoid Dendritic Cells and Their Role in AutoimmuneRheumatic Diseases

Eloranta, Maija-Leena; Alm, Gunnar V; Rönnblom, Lars

Ingår i Arthritis and Rheumatism, s. 853-863, 2013

• DOI för Disease Mechanisms in RheumatologyTools and Pathways: Plasmacytoid Dendritic Cells and Their Role in AutoimmuneRheumatic Diseases

NCR3/NKp30 Contributes to Pathogenesis in Primary Sjögren's Syndrome

Rusakiewicz, Sylvie; Nocturne, Gaetane; Lazure, Thierry; Semeraro, Michaela et al.

Ingår i Science Translational Medicine, 2013

• DOI för NCR3/NKp30 Contributes to Pathogenesis in Primary Sjögren's Syndrome

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer L; Wahlberg, Per; Busche, Stephan et al.

Ingår i Genome Biology, 2013

• DOI för Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility

Wang, Chuan; Ahlford, Annika; Laxman, Navya; Nordmark, Gunnel et al.

Ingår i Genes and Immunity, s. 217-222, 2013

• DOI för Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
• Ladda ner fulltext (pdf) av Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility

Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

Wang, Chuan; Ahlford, Annika; Järvinen, Tiina M; Nordmark, Gunnel et al.

Ingår i European Journal of Human Genetics, s. 994-999, 2013

• DOI för Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis

Bolin, Karin; Sandling, Johanna K; Zickert, Agneta; Jönsen, Andreas et al.

Ingår i PLOS ONE, 2013

• DOI för Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis
• Ladda ner fulltext (pdf) av Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis

Epitopes of Microbial and Human Heat Shock Protein 60 and Their Recognition in Myalgic Encephalomyelitis

Elfaitouri, Amal; Herrmann, Björn; Bölin-Wiener, Agnes; Wang, Yilin et al.

Ingår i PLOS ONE, s. 55, 2013

• DOI för Epitopes of Microbial and Human Heat Shock Protein 60 and Their Recognition in Myalgic Encephalomyelitis
• Ladda ner fulltext (pdf) av Epitopes of Microbial and Human Heat Shock Protein 60 and Their Recognition in Myalgic Encephalomyelitis

Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4

Wang, Chuan; Sandling, Johanna K; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 96-103, 2013

• DOI för Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4

HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

Lundström, Emeli; Gustafsson, Johanna T; Jönsen, Andreas; Leonard, Dag et al.

Ingår i Annals of the Rheumatic Diseases, s. 1018-1025, 2013

• DOI för HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

The NKp30/B7H6 Axis Contributes To Pathogenesis In Primary Sjogren's Syndrome.

Nocturne, Gaetane; Rusakiewicz, Sylvie; Sene, Damien; Nordmark, Gunnel et al.

Ingår i Arthritis and Rheumatism, 2013

Systemic Lupus Erythematosus Immune Complexes Increase the Expression of SLAM Family Members CD319 (CRACC) and CD229 (LY-9) on Plasmacytoid Dendritic Cells and CD319 on CD56(dim) NK Cells

Hagberg, Niklas; Theorell, Jakob; Schlums, Heinrich; Eloranta, Maija-Leena et al.

Ingår i Journal of Immunology, s. 2989-2998, 2013

• DOI för Systemic Lupus Erythematosus Immune Complexes Increase the Expression of SLAM Family Members CD319 (CRACC) and CD229 (LY-9) on Plasmacytoid Dendritic Cells and CD319 on CD56(dim) NK Cells

On the Origin of the Type I Interferon Activity in Rheumatoid Arthritis

de Jong, T. D.; Vosslamber, S.; Eloranta, Maija-Leena; Rönnblom, Lars et al.

Ingår i Annals of the Rheumatic Diseases, 2013

• DOI för On the Origin of the Type I Interferon Activity in Rheumatoid Arthritis

Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

Leonard, Dag; Svenungsson, Elisabet; Sandling, Johanna K; Berggren, Olof et al.

Ingår i Circulation, s. 255-263, 2013

• DOI för Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

Complex Functional Effects Within The HLA Contribute To Sjogren's Syndrome Pathogenesis and May Influence Both Transcriptional Regulation and Peptide Binding

Lessard, Christopher J.; Li, He; Adrianto, Indra; Ice, John A. et al.

Ingår i Arthritis and Rheumatism, 2013

Direct and Indirect Costs For Patients With Systemic Lupus Erythematosus In National Cohorts In Sweden

Jonsen, Andreas; Bengtsson, Anders A.; Bengtsson, Christine; Gunnarsson, Iva et al.

Ingår i Arthritis and Rheumatism, 2013

Coronary Heart Disease in Systemic Lupus Erythematosus is Associated with Interferon Regulatory Factor 8 Gene Variants

Leonard, Dag; Svenungsson, E.; Sandling, J. K.; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 270-270, 2013

• DOI för Coronary Heart Disease in Systemic Lupus Erythematosus is Associated with Interferon Regulatory Factor 8 Gene Variants

Type I Interferonopathies

Rönnblom, Lars

Ingår i Annals of the Rheumatic Diseases, s. 8-8, 2013

• DOI för Type I Interferonopathies

Identification of Multiple Sjogren'S Syndrome Susceptibility Loci

Lessard, C. J.; Li, H.; Ice, J. A.; Adrianto, I. et al.

Ingår i Annals of the Rheumatic Diseases, s. 54-55, 2013

• DOI för Identification of Multiple Sjogren'S Syndrome Susceptibility Loci

IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE – a possible new treatment?

Lood, Christian; Allhorn, Maria; Lood, Rolf; Gullstrand, Birgitta et al.

Ingår i Annals of the Rheumatic Diseases, 2012

• DOI för IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE – a possible new treatment?

Pharmacokinetics, tolerability, and preliminary efficacy of ABR-215757, a new quinoline-3-carboxamide derivative, in murine and human SLE

Bengtsson, Anders A; Sturfelt, Gunnar; Lood, Christian; Rönnblom, Lars et al.

Ingår i Arthritis and Rheumatism, s. 1579-1588, 2012

• DOI för Pharmacokinetics, tolerability, and preliminary efficacy of ABR-215757, a new quinoline-3-carboxamide derivative, in murine and human SLE

Autoantibodies associated with RNA are more enriched than anti-dsDNA antibodies in circulating immune complexes in SLE

Åhlin, Erik; Mathsson, Linda; Eloranta, Maija-Leena; Jonsdottir, Thorunn et al.

Ingår i Lupus, s. 586-595, 2012

• DOI för Autoantibodies associated with RNA are more enriched than anti-dsDNA antibodies in circulating immune complexes in SLE

Association between genetic variants in the tumour necrosis factor/lymphotoxin α/lymphotoxin β locus and primary Sjogren's syndrome in Scandinavian samples

Bolstad, Anne Isine; Le Hellard, Stephanie; Kristjansdottir, Gudlaug; Vasaitis, Lilian et al.

Ingår i Annals of the Rheumatic Diseases, s. 981-988, 2012

• DOI för Association between genetic variants in the tumour necrosis factor/lymphotoxin α/lymphotoxin β locus and primary Sjogren's syndrome in Scandinavian samples

Association of STAT4, IRF5 and BLK polymorphisms with severity and outcome in lupus nephritis

Eriksson, Karin G.; Zickert, Agneta; Sandling, Johanna K.; Jonsen, Andreas et al.

Ingår i Annals of the Rheumatic Diseases, 2012

• DOI för Association of STAT4, IRF5 and BLK polymorphisms with severity and outcome in lupus nephritis

SLE immune complexes upregulate the expression of slamf7 (cd319) on plasmacytoid dendritic cells

Hagberg, Niklas; Theorell, Jakob; Alm, Gunnar V.; Eloranta, Maija-Leena et al.

Ingår i Annals of the Rheumatic Diseases, 2012

• DOI för SLE immune complexes upregulate the expression of slamf7 (cd319) on plasmacytoid dendritic cells

 Reumatologisk forskning med försöksdjur är viktig för våra patienter: [Rheumatologic research with animal experiments is important for our patients]

Rudin, Anna; Sturfelt, Gunnar; Carlsten, Hans; Hafström, Ingiäld et al.

Ingår i Läkartidningen, s. 40-40, 2012

Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons

Stone, Rivka C; Feng, Di; Deng, Jing; Singh, Sukhwinder et al.

Ingår i Arthritis and Rheumatism, s. 788-798, 2012

• DOI för Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons

Variation of Interferon-Alpha Production in Healthy Individuals and Association with Autoimmune Susceptibility Genes

Berggren, Olof; Alexsson, Andrei; Alm, Gunnar V.; Syvanen, Ann-Christine et al.

Ingår i Arthritis and Rheumatism, 2012

Genetic Variation in the NCR3 Locus Is Associated with Anti-SSA/SSB Positive Primary Sjogren's Syndrome in Scandinavian Samples

Nordmark, Gunnel; Eloranta, Maija-Leena; Eriksson, Per; Theander, Elke et al.

Ingår i Arthritis and Rheumatism, 2012

Systemic Lupus Erythematosus Immune Complexes Upregulate the Expression of CD319 and CD229 On Plasmacytoid Dendritic Cells

Hagberg, Niklas; Theorell, Jakob; Alm, Gunnar V.; Eloranta, Maija-Leena et al.

Ingår i Arthritis and Rheumatism, 2012

On the Origin of the Type I Interferon Signature in Rheumatoid Arthritis

de Jong, T. D.; Vosslamber, Saskia; Eloranta, Maija-Leena; Rönnblom, Lars et al.

Ingår i Arthritis and Rheumatism, 2012

B lymphocytes enhance the interferon-α production by plasmacytoid dendritic cells

Berggren, Olof; Hagberg, Niklas; Weber, Gert; Alm, Gunnar V et al.

Ingår i Arthritis and Rheumatism, s. 3409-3419, 2012

• DOI för B lymphocytes enhance the interferon-α production by plasmacytoid dendritic cells

IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE: a possible new treatment?

Lood, Christian; Allhorn, Maria; Lood, Rolf; Gullstrand, Birgitta et al.

Ingår i Arthritis and Rheumatism, s. 2698-2706, 2012

• DOI för IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE: a possible new treatment?

IFN-α Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1β and LFA-1

Hagberg, Niklas; Berggren, Olof; Leonard, Dag; Weber, Gert et al.

Ingår i Journal of Immunology, s. 5085-5094, 2011

• DOI för IFN-α Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1β and LFA-1

Increased carotid intima thickness and decreased media thickness in premenopausal women with systemic lupus erythematosus: an investigation by non-invasive high-frequency ultrasound

Leonard, Dag; Akhter, Tansim; Nordmark, Gunnel; Rönnblom, Lars et al.

Ingår i Scandinavian Journal of Rheumatology, s. 279-282, 2011

• DOI för Increased carotid intima thickness and decreased media thickness in premenopausal women with systemic lupus erythematosus: an investigation by non-invasive high-frequency ultrasound

Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

Jonsen, Andreas; Nilsson, Sara C; Ahlqvist, Emma; Svenungsson, Elisabet et al.

Ingår i Arthritis Research & Therapy, 2011

• DOI för Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome

Nordmark, Gunnel; Kristjansdottir, Gudlaug; Theander, E.; Appel, S. et al.

Ingår i Genes and Immunity, s. 100-109, 2011

• DOI för Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome

Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome

Appel, Silke; Le Hellard, Stephanie; Bruland, Ove; Brun, Johan G. et al.

Ingår i Annals of the Rheumatic Diseases, s. 1327-1329, 2011

• DOI för Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome

TSGA10-A Target for Autoantibodies in Autoimmune Polyendocrine Syndrome Type 1 and Systemic Lupus Erythematosus

Smith, C. J. A.; Oscarson, M.; Rönnblom, Lars; Alimohammadi, Mohammad et al.

Ingår i Scandinavian Journal of Immunology, s. 147-153, 2011

• DOI för TSGA10-A Target for Autoantibodies in Autoimmune Polyendocrine Syndrome Type 1 and Systemic Lupus Erythematosus

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE

Sandling, Johanna K.; Garnier, Sophie; Sigurdsson, Snaevar; Wang, Chuan et al.

Ingår i European Journal of Human Genetics, s. 479-484, 2011

• DOI för A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

Cunninghame Graham, Deborah S; Morris, David L; Bhangale, Tushar R; Criswell, Lindsey A et al.

Ingår i PLoS genetics, 2011

• DOI för Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

Type I interferon system activation and association with disease manifestations in systemic sclerosis

Eloranta, Maija-Leena; Franck-Larsson, Karin; Lövgren, Tanja; Kalamajski, Sebastian et al.

Ingår i Annals of the Rheumatic Diseases, s. 1396-1402, 2010

• DOI för Type I interferon system activation and association with disease manifestations in systemic sclerosis

Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus

Feng, Di; Stone, Rivka C.; Eloranta, Maija-Leena; Sangster-Guity, Niquiche et al.

Ingår i Arthritis and Rheumatism, s. 562-573, 2010

• DOI för Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus

Cytokines as therapeutic targets in SLE

Rönnblom, Lars; Elkon, Keith B.

Ingår i Nature Reviews Rheumatology, s. 339-347, 2010

• DOI för Cytokines as therapeutic targets in SLE

A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

Svenungsson, Elisabet; Gustafsson, Johanna; Leonard, Dag; Sandling, Johanna et al.

Ingår i Annals of the Rheumatic Diseases, s. 834-840, 2010

• DOI för A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

Lood, Christian; Gullstrand, Birgitta; Truedsson, Lennart; Olin, Anders I. et al.

Ingår i Arthritis and Rheumatism, s. 3081-3090, 2009

• DOI för C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

Interferon-alpha Mediates Suppression of C-Reactive Protein Explanation for Muted C-Reactive Protein Response in Lupus Flares?

Enocsson, Helena; Sjöwall, Christopher; Skogh, Thomas; Eloranta, Maija-Leena et al.

Ingår i Arthritis and Rheumatism, s. 3755-3760, 2009

• DOI för Interferon-alpha Mediates Suppression of C-Reactive Protein Explanation for Muted C-Reactive Protein Response in Lupus Flares?

Systemic lupus erythematosus: a matter of life and death

Pisetsky, David S.; Rönnblom, Lars

Ingår i Arthritis and Rheumatism, s. 1567-1570, 2009

• DOI för Systemic lupus erythematosus: a matter of life and death

Use of a commercial line blot assay as a screening test for autoantibodies in inflammatory myopathies

Rönnelid, Johan; Barbasso Helmers, Sevim; Storfors, Helena; Grip, Katarina et al.

Ingår i Autoimmunity Reviews, s. 58-61, 2009

• DOI för Use of a commercial line blot assay as a screening test for autoantibodies in inflammatory myopathies

Systemic Lupus Erythematosus: a matter of life and death

Pisetsky, David S.; Rönnblom, Lars

Ingår i Arthritis and Rheumatism, s. 1567-1570, 2009

• DOI för Systemic Lupus Erythematosus: a matter of life and death

Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE

Isaksson, Magnus; Ardesjö, Brita; Rönnblom, Lars; Kämpe, Olle et al.

Ingår i European Journal of Immunology, s. 2925-2935, 2009

• DOI för Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE

Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells

Eloranta, Maija-Leena; Lövgren, Tanja; Finke, Doreen; Mathsson, Linda et al.

Ingår i Arthritis and Rheumatism, s. 2418-2427, 2009

• DOI för Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells

Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome

Nordmark, Gunnel; Kristjansdottir, Gudlaug; Theander, E.; Eriksson, P. et al.

Ingår i Genes and Immunity, s. 68-76, 2009

• DOI för Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

Gateva, Vesela; Sandling, Johanna K.; Hom, Geoff; Taylor, Kimberly E. et al.

Ingår i Nature Genetics, s. 1228-1233, 2009

• DOI för A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX

Hom, Geoffrey; Graham, Robert R; Modrek, Barmak; Taylor, Kimberly E et al.

Ingår i New England Journal of Medicine, s. 900-909, 2008

• DOI för Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

Sigurdsson, Snaevar; Nordmark, Gunnel; Garnier, Sophie; Grundberg, Elin et al.

Ingår i Human Molecular Genetics, s. 2868-2876, 2008

• DOI för A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

The innate immune system in SLE: type I interferons and dendritic cells

Rönnblom, Lars; Pascual, V.

Ingår i Lupus, s. 394-399, 2008

• DOI för The innate immune system in SLE: type I interferons and dendritic cells

Serum levels of sex steroid hormones and matrix metalloproteinases after intra-articular glucocorticoid treatment in female patients with rheumatoid arthritis

Weitoft, Tomas; Larsson, Anders; Rönnblom, Lars

Ingår i Annals of the Rheumatic Diseases, s. 422-424, 2008

• DOI för Serum levels of sex steroid hormones and matrix metalloproteinases after intra-articular glucocorticoid treatment in female patients with rheumatoid arthritis

Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

Sigurdsson, Snaevar; Göring, Harald H. H.; Kristjansdottir, Gudlaug; Milani, Lili et al.

Ingår i Human Molecular Genetics, s. 872-881, 2008

• DOI för Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

Graham, R. Robert; Kyogoku, Chieko; Sigurdsson, Snaevar; Vlasova, Irina A. et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 6758-6763, 2007

• DOI för Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

A polymorphic variant in the MHC2TA gene is not associated with systemic lupus erythematosus

Linga-Reddy, M. V. Prasad; Gunnarsson, I; Svenungsson, E; Sturfelt, G et al.

Ingår i Tissue Antigens, s. 412-414, 2007

• DOI för A polymorphic variant in the MHC2TA gene is not associated with systemic lupus erythematosus

Association of a Haplotype in the Promoter Region of the Interferon Regulatory Factor 5 Gene With Rheumatoid Arthritis

Sigurdsson, Snaevar; Padyukov, Leonid; Kurreeman, Fina A.S.; Liljedahl, Ulrika et al.

Ingår i Arthritis and Rheumatism, s. 2202-2210, 2007

• DOI för Association of a Haplotype in the Promoter Region of the Interferon Regulatory Factor 5 Gene With Rheumatoid Arthritis

A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti-Jo-1 or anti-Ro 52/anti-Ro 60 autoantibodies

Eloranta, Maija-Leena; Helmers, Sevim Barbasso; Ulfgren, Ann-Kristin; Rönnblom, Lars et al.

Ingår i Arthritis and Rheumatism, s. 3112-3124, 2007

• DOI för A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti-Jo-1 or anti-Ro 52/anti-Ro 60 autoantibodies

Induction of interferon-α by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA

Lövgren, Tanja; Eloranta, Maija-Leena; Kastner, Berthold; Wahren-Herlenius, Marie et al.

Ingår i Arthritis and Rheumatism, s. 1917-1927, 2006

• DOI för Induction of interferon-α by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA

Glucocorticoid resorption and influence on the hypothalamic-pituitary-adrenal axis after intra-articular treatment of the knee in resting and mobile patients.

Weitoft, T; Rönnblom, L

Ingår i Ann Rheum Dis, s. 955-7, 2006

Betungande regler för klinisk forskning står inte i proportion till patientnyttan

Vahlquist, Anders; Westermark, Per; Ståhle, Elisabeth; Venge, Per et al.

Ingår i Läkartidningen, s. 1832-1834, 2005

Betungande regler för klinisk prövning står inte i proportion till patientnyttan

Vahlquist, Anders; Westermark, Per; Ståhle, Elisabeth; Venge, Per et al.

Ingår i Läkartidningen, s. 1832-1834, 2005

Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanism

Båve, Ullvi; Nordmark, Gunnel; Lövgren, Tanja; Rönnelid, Johan et al.

Ingår i Arthritis and Rheumatism, s. 1185-1195, 2005

• DOI för Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanism

Effects of Dehydroepiandrosterone Supplement on Health-related Quality of Life in Glucocorticoid Treated Female Patients with Systemic Lupus Erythematosus

Nordmark, Gunnel; Bengtsson, Christine; Larsson, Anders; Karlsson, Anders et al.

Ingår i Autoimmunity, s. 531-540, 2005

• DOI för Effects of Dehydroepiandrosterone Supplement on Health-related Quality of Life in Glucocorticoid Treated Female Patients with Systemic Lupus Erythematosus

Changes of cartilage and bone markers after intra- articular glucocorticoid treatment with and without postinjection rest in patients with rheumatoid arthritis

Weitoft, Tomas; Larsson, Anders; Saxne, Tore; Rönnblom, Lars

Ingår i Annals of the Rheumatic Diseases, s. 1750-1753, 2005

• DOI för Changes of cartilage and bone markers after intra- articular glucocorticoid treatment with and without postinjection rest in patients with rheumatoid arthritis

Thrombotic disease in systemic lupus erythematosus is associated with a maintained systemic platelet activation.

Nilsson Ekdahl, Kristina; Bengtsson, Anders A; Andersson, Jonas; Elgue, Graciela et al.

Ingår i Br J Haematol, s. 74, 2004

Induction of interferon-α production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG

Lövgren, Tanja; Eloranta, Maija-Leena; Båve, Ullvi; Alm, Gunnar V. et al.

Ingår i Arthritis and Rheumatism, s. 1861-1872, 2004

• DOI för Induction of interferon-α production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG

The heterogeneity of neuropsychiatric systemic lupus erythematosus isreflected in lack of association with cerebrospinal fluid cytokineprofiles

Jonsen, A; Bengtsson, AA; Nived, O; Ryberg, B et al.

Ingår i Lupus, s. 846-850, 2003

Single-tube nested quantitative PCR: a rational and sensitive technique for detection of retroviral DNA. Application to RERV-H/HRV-5 and confirmation of its rabbit origin

Forsman, Anna; Uzameckis, Dmitrijs; Rönnblom, Lars; Baecklund, Eva et al.

Ingår i Journal of Virological Methods, s. 1-11, 2003

• DOI för Single-tube nested quantitative PCR: a rational and sensitive technique for detection of retroviral DNA. Application to RERV-H/HRV-5 and confirmation of its rabbit origin

Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG

Båve, Ullvi; Magnuson, Mattias; Eloranta, Maija-Leena; Perers, Anders et al.

Ingår i Journal of Immunology, s. 3296-302, 2003

Autoantibodies to alpha-fodrin in primary Sjogren's syndrome and SLEdetected by an in vitro transcription and translation assay.

Nordmark, G; Rorsman, F; Ronnblom, L; Cajander, S et al.

Ingår i Clin Exp Rheumatol, s. 49, 2003

Randomised controlled study of postinjection immobilisation after intra-articular glucocorticoid treatment for wrist synovitis.

Weitoft, T; Rönnblom, L

Ingår i Ann Rheum Dis, s. 1013-5, 2003

Identification of AHNAK as a novel autoantigen in systemic lupuserythematosus

Sköldberg, Filip; Rönnblom, Lars; Thornemo, M; Lindahl, A et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 951-958, 2002

• DOI för Identification of AHNAK as a novel autoantigen in systemic lupuserythematosus

An etiopathogenic role for the type I IFN system in SLE.

Ronnblom, L; Alm, GV

Ingår i Trends Immunol, s. 427, 2001

The combination of apoptotic U937 cells and lupus IgG is a potent IF inducer

Båve, Ullvi; Alm, Gunar V.; Rönnblom, Lars

Ingår i Journal of Immunology, s. 3519-26, 2000

Systemic lupus erythematosus: from an adverse event of interferon administration to a disease with new treatment options

Rönnblom, Lars

Ingår i Upsala Journal of Medical Sciences, 2025

• DOI för Systemic lupus erythematosus: from an adverse event of interferon administration to a disease with new treatment options
• Ladda ner fulltext (pdf) av Systemic lupus erythematosus: from an adverse event of interferon administration to a disease with new treatment options

Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

Burska, Agata; Rodriguez-Carrio, Javier; Biesen, Robert; Dik, Willem A. et al.

Ingår i RMD Open, 2023

• DOI för Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
• Ladda ner fulltext (pdf) av Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

Rodriguez-Carrio, Javier; Burska, Agata; Conaghan, P. G.; Dik, Willem A. et al.

Ingår i RMD Open, 2023

• DOI för Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
• Ladda ner fulltext (pdf) av Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

Technological readiness and implementation of genomic-driven precision medicine for complex diseases

Franks, P. W.; Melén, E.; Friedman, M.; Sundström, Johan et al.

Ingår i Journal of Internal Medicine, s. 602-620, 2021

• DOI för Technological readiness and implementation of genomic-driven precision medicine for complex diseases
• Ladda ner fulltext (pdf) av Technological readiness and implementation of genomic-driven precision medicine for complex diseases

Type I interferons in host defence and inflammatory diseases

Crow, Mary K.; Rönnblom, Lars

Ingår i Lupus Science and Medicine, 2019

• DOI för Type I interferons in host defence and inflammatory diseases
• Ladda ner fulltext (pdf) av Type I interferons in host defence and inflammatory diseases

Interferon pathway in SLE: one key to unlocking the mystery of the disease

Rönnblom, Lars; Leonard, Dag

Ingår i Lupus Science and Medicine, 2019

• DOI för Interferon pathway in SLE: one key to unlocking the mystery of the disease
• Ladda ner fulltext (pdf) av Interferon pathway in SLE: one key to unlocking the mystery of the disease

An update on the role of type I interferons in systemic lupus erythematosus and Sjogren's syndrome

Thorlacius, Gudny Ella; Wahren-Herlenius, Marie; Rönnblom, Lars

Ingår i Current Opinion in Rheumatology, s. 471-481, 2018

• DOI för An update on the role of type I interferons in systemic lupus erythematosus and Sjogren's syndrome

Report of the inaugural Interferon Research Summit: interferon in inflammatory diseases

Crow, Mary K.; Rönnblom, Lars

Ingår i Lupus Science and Medicine, 2018

• DOI för Report of the inaugural Interferon Research Summit: interferon in inflammatory diseases
• Ladda ner fulltext (pdf) av Report of the inaugural Interferon Research Summit: interferon in inflammatory diseases

Systemic lupus erythematosus: still a challenge for physicians

Bengtsson, A. A.; Rönnblom, Lars

Ingår i Journal of Internal Medicine, s. 52-64, 2017

• DOI för Systemic lupus erythematosus: still a challenge for physicians

Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts

Jönsen, Andreas; Hjalte, Frida; Willim, Minna; Carlsson, Katarina Steen et al.

Ingår i Seminars in Arthritis & Rheumatism, s. 684-690, 2016

• DOI för Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts

Systemic lupus erythematosus: a disease with a dysregulated type I interferon system

Hagberg, Niklas; Rönnblom, Lars

Ingår i Scandinavian Journal of Immunology, s. 199-207, 2015

• DOI för Systemic lupus erythematosus: a disease with a dysregulated type I interferon system

Type I Interferons in Sjögren's Syndrome

Yao, Yihong; Liu, Zheng; Jallal, Bahija; Shen, Nan et al.

Ingår i Autoimmunity Reviews, s. 558-566, 2013

• DOI för Type I Interferons in Sjögren's Syndrome

The interferon signature in autoimmune diseases

Rönnblom, Lars; Eloranta, Maija-Leena

Ingår i Current Opinion in Rheumatology, s. 248-253, 2013

• DOI för The interferon signature in autoimmune diseases

Primary Sjögren's syndrome and the type I interferon system

Nordmark, Gunnel; Eloranta, Maija-Leena; Rönnblom, Lars

Ingår i Current Pharmaceutical Biotechnology, s. 2054-2062, 2012

The type I interferon system in the etiopathogenesis of autoimmune diseases

Rönnblom, Lars

Ingår i Upsala Journal of Medical Sciences, s. 227-237, 2011

• DOI för The type I interferon system in the etiopathogenesis of autoimmune diseases

The type I interferon system in the development of lupus

Rönnblom, Lars; Alm, Gunnar V; Eloranta, Maija-Leena

Ingår i Seminars in Immunology, s. 113-121, 2011

• DOI för The type I interferon system in the development of lupus

Potential role of IFNα in adult lupus

Rönnblom, Lars

Ingår i Arthritis Research & Therapy, 2010

• Ladda ner fulltext (pdf) av Potential role of IFNα in adult lupus

Endogenous type I interferon inducers in autoimmune diseases

Finke, Doreen; Eloranta, Maija-Leena; Rönnblom, Lars

Ingår i Autoimmunity, s. 349-352, 2009

• DOI för Endogenous type I interferon inducers in autoimmune diseases

Type I interferon and lupus

Rönnblom, Lars; Alm, Gunnar V.; Eloranta, Maija-Leena

Ingår i Current Opinion in Rheumatology, s. 471-477, 2009

• DOI för Type I interferon and lupus

The Interferon System in Lupus Erythematosus

Hagberg, Niklas; Rönnblom, Lars

Ingår i Systemic Lupus Erythematosus, s. 153-158, Academic Press, 2016

• DOI för The Interferon System in Lupus Erythematosus

The interferons. Further targeted therapies in rheumatology

Rönnblom, Lars; Eloranta, Maija-Leena; Alm, Gunnar

Ingår i Informa Healthcare, 2007

Polymorphisms in the Interferon Regulatory Factor 5 Gene are Associated with Anti-cyclic Citrullinated Peptide Antibody Negative Rheumatoid Arthritis

Sigurdsson, Snaevar; Padyukov, Leonid; Liljedahl, Ulrika; Alfredsson, Lars et al.

2012

Activated T cells enhance interferon-alpha production by plasmacytoid dendritic cells stimulated by RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Dissection of genes in the type I interferon pathway reveals two novel risk loci for SLE

Sandling, Johanna K; Garnier, Sophie; Sigurdsson, Snaevar; Wang, Chuan et al.

From genetic predisposition to clinical outcome in systemic lupus erythematosus: construction and validation of sub-phenotype-specific genetic risk scores

Reid, Sarah; Sandling, Johanna K.; Pucholt, Pascal; Sayadi, Ahmed et al.

Variants in BANK1 are associated with lupus nephritis

Bolin, Karin; Leonard, Dag; Sandling, Johanna K.; Imgenberg-Kreuz, Juliana et al.