Oleg Dyachok

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

Ibrahim, Hazem; Balboa, Diego; Saarimäki-Vire, Jonna; Montaser, Hossam et al.

Ingår i Diabetologia, s. 1642-1662, 2024

• DOI för RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function
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The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling

Sanchez, Gonzalo; Incedal, Tugce Ceren; Prada, Juan; O'Callaghan, Paul et al.

Ingår i Journal of Cell Biology, 2023

• DOI för The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling
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Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells

Yang, Mingyu; Dyachok, Oleg; Xu, Yunjian; Gylfe, Erik et al.

Ingår i Cellular Signalling, 2023

• DOI för Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells
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Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging

Dyachok, Oleg; Xu, Yunjian; Idevall, Olof; Tengholm, Anders

Ingår i cAMP Signaling, s. 319-338, Humana Press, 2022

• DOI för Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.

Balboa, Diego; Barsby, Tom; Lithovius, Väinö; Saarimäki-Vire, Jonna et al.

Ingår i Nature Biotechnology, s. 1042-1055, 2022

• DOI för Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.
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RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

Ibrahim, Hazem; Balboa, Diego; Saarimäki-Vire, Jonna; Montaser, Hossam et al.

Ingår i Diabetologia, s. 1642-1662, 2024

• DOI för RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function
• Ladda ner fulltext (pdf) av RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling

Sanchez, Gonzalo; Incedal, Tugce Ceren; Prada, Juan; O'Callaghan, Paul et al.

Ingår i Journal of Cell Biology, 2023

• DOI för The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling
• Ladda ner fulltext (pdf) av The β-cell primary cilium is an autonomous Ca²⁺ compartment for paracrine GABA signaling

Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells

Yang, Mingyu; Dyachok, Oleg; Xu, Yunjian; Gylfe, Erik et al.

Ingår i Cellular Signalling, 2023

• DOI för Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells
• Ladda ner fulltext (pdf) av Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic & beta;-cells

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.

Balboa, Diego; Barsby, Tom; Lithovius, Väinö; Saarimäki-Vire, Jonna et al.

Ingår i Nature Biotechnology, s. 1042-1055, 2022

• DOI för Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.
• Ladda ner fulltext (pdf) av Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.

Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

Kononenko, Olga; Bazov, Igor; Watanabe, Hiroyuki; Gerashchenko, Ganna et al.

Ingår i Biochimica et Biophysica Acta, s. 246-255, 2017

• DOI för Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

Abels, Mia; Riva, Matteo; Bennet, Hedvig; Ahlqvist, Emma et al.

Ingår i Diabetologia, s. 1928-1937, 2016

• DOI för CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

CART is a novel glucose-dependent peptide with antidiabetic actions in humans

Abels, M.; Riva, M.; Poon, W.; Bennet, H. et al.

Ingår i Diabetologia, 2015

Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Alenkvist, Ida; Dyachok, Oleg; Tian, Geng; Li, Jia et al.

Ingår i Journal of Endocrinology, s. 267-275, 2014

• DOI för Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets
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Functional differences between aggregated and dispersed insulin-producing cells

Chowdhury, Azazul Islam; Dyachok, Oleg; Tengholm, Anders; Sandler, Stellan et al.

Ingår i Diabetologia, s. 1557-1568, 2013

• DOI för Functional differences between aggregated and dispersed insulin-producing cells
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Ghrelin Attenuates cAMP-PKA Signaling to Evoke Insulinostatic Cascade in Islet beta-Cells

Dezaki, Katsuya; Damdindorj, Boldbaatar; Sone, Hideyuki; Dyachok, Oleg et al.

Ingår i Diabetes, s. 2315-2324, 2011

• DOI för Ghrelin Attenuates cAMP-PKA Signaling to Evoke Insulinostatic Cascade in Islet beta-Cells

Ca2+ and cAMP Signaling in Human Embryonic Stem Cell-Derived Dopamine Neurons

Malmersjö, Seth; Liste, Isabel; Dyachok, Oleg; Tengholm, Anders et al.

Ingår i Stem Cells and Development, s. 1355-1364, 2010

• DOI för Ca2+ and cAMP Signaling in Human Embryonic Stem Cell-Derived Dopamine Neurons

Crosstalk between cAMP- and Zn2+-signalling in insulin secretion

Dyachok, Oleg; Idevall, Olof; Tengholm, Anders; Gylfe, Erik

Ingår i Diabetologia, 2010

Wnt-5a-induced Phosphorylation of DARPP-32 Inhibits Breast Cancer Cell Migration in a CREB-dependent Manner

Hansen, Christian; Howlin, Jillian; Tengholm, Anders; Dyachok, Oleg et al.

Ingår i Journal of Biological Chemistry, s. 27533-27543, 2009

• DOI för Wnt-5a-induced Phosphorylation of DARPP-32 Inhibits Breast Cancer Cell Migration in a CREB-dependent Manner

Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion

Dyachok, Oleg; Idevall-Hagren, Olof; Sågetorp, Jenny; Tian, Geng et al.

Ingår i Cell Metabolism, s. 26-37, 2008

• DOI för Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
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Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells.

Dyachok, Oleg; Isakov, Yegor; Sågetorp, Jenny; Tengholm, Anders

Ingår i Nature, s. 349-52, 2006

cAMP oscillations restrict protein kinase A redistribution in insulin-secreting cells.

Dyachok, O; Sagetorp, J; Isakov, Y; Tengholm, A

Ingår i Biochem Soc Trans, s. 498-501, 2006

Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca²⁺ in insulin-secreting β-cells

Thore, Sophia; Dyachok, Oleg; Gylfe, Erik; Tengholm, Anders

Ingår i Journal of Cell Science, s. 4463-4471, 2005

• DOI för Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca²⁺ in insulin-secreting β-cells
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Ca²⁺-induced Ca²⁺ release by activation of inositol 1,4,5-trisphosphate receptors in primary pancreatic β-cells

Dyachok, Oleg; Tufveson, Gunnar; Gylfe, Erik

Ingår i Cell Calcium, s. 1-9, 2004

• DOI för Ca²⁺-induced Ca²⁺ release by activation of inositol 1,4,5-trisphosphate receptors in primary pancreatic β-cells
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Ca²+-induced Ca²+ Release via Inositol 1,4,5-trisphosphate Receptors Is Amplified by Protein Kinase A and Triggers Exocytosis in Pancreatic β-Cells

Dyachok, Oleg; Gylfe, Erik

Ingår i Journal of Biological Chemistry, s. 45455-45461, 2004

• DOI för Ca²+-induced Ca²+ Release via Inositol 1,4,5-trisphosphate Receptors Is Amplified by Protein Kinase A and Triggers Exocytosis in Pancreatic β-Cells
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Oscillations of Phospholipase C Activity Triggered by Depolarizatio and Ca2+ Influx in Insulin-secreting Cells

Thore, Sophia; Dyachok, Oleg; Tengholm, Anders

Ingår i The Journal of Biological Chemistry (JBC), s. 19396-19400, 2004

Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging

Dyachok, Oleg; Xu, Yunjian; Idevall, Olof; Tengholm, Anders

Ingår i cAMP Signaling, s. 319-338, Humana Press, 2022

• DOI för Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging