Christel Bergström
Professor vid Institutionen för farmaci; Molekylär galenisk farmaci
- Telefon:
- 018-471 41 18
- Mobiltelefon:
- 073-469 76 22
- E-post:
- christel.bergstrom@uu.se
- Besöksadress:
- Biomedicinskt Centrum BMC, Husargatan 3
- Postadress:
- Box 580
751 23 UPPSALA
- Akademiska meriter:
- FarmM
- CV:
- Ladda ned CV
Kort presentation
Här beskriver jag min forskning: https://media.medfarm.uu.se/play/kanal/515/video/9739
Nyckelord
- drug delivery
- solubility
- computational pharmaceutics
- virtual intestine
- enabling formulations
- personalised medicines
- digestion
- absorption
Forskning
Här beskriver jag min forskning:
https://media.medfarm.uu.se/play/kanal/515/video/9739
Media
Installationsföreläsning Nov 16 2021
Installationsföreläsning över ämnet Molekylär galenisk farmaci. Personliga reflektioner över datorbaserad läkemedelsformulering, 3D skrivna läkemedel och en akademsik karriär.

Publikationer
Senaste publikationer
Ingår i Molecular Pharmaceutics, 2025
- DOI för Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
- Ladda ner fulltext (pdf) av Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
Ingår i Journal of Pharmaceutical Sciences, s. 458-467, 2025
- DOI för Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
- Ladda ner fulltext (pdf) av Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
Ingår i Journal of Colloid and Interface Science, s. 287-300, 2025
- DOI för Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
- Ladda ner fulltext (pdf) av Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
Ingår i Chemistry and Physics of Lipids, 2024
- DOI för Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane
- Ladda ner fulltext (pdf) av Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane
Ingår i Journal of Controlled Release, 2024
- DOI för Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
- Ladda ner fulltext (pdf) av Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
Alla publikationer
Artiklar i tidskrift
Ingår i Molecular Pharmaceutics, 2025
- DOI för Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
- Ladda ner fulltext (pdf) av Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
Ingår i Journal of Pharmaceutical Sciences, s. 458-467, 2025
- DOI för Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
- Ladda ner fulltext (pdf) av Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
Ingår i Journal of Colloid and Interface Science, s. 287-300, 2025
- DOI för Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
- Ladda ner fulltext (pdf) av Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
Ingår i Chemistry and Physics of Lipids, 2024
- DOI för Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane
- Ladda ner fulltext (pdf) av Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane
Ingår i Journal of Controlled Release, 2024
- DOI för Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
- Ladda ner fulltext (pdf) av Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
Ingår i International Journal of Pharmaceutics, 2024
- DOI för Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics
- Ladda ner fulltext (pdf) av Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics
Ingår i International Journal of Pharmaceutics, 2024
Ingår i Molecular Pharmaceutics, s. 5261-5271, 2024
- DOI för Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set
- Ladda ner fulltext (pdf) av Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set
Development of a canine artificial colonic mucus model for drug diffusion studies
Ingår i European Journal of Pharmaceutical Sciences, 2024
- DOI för Development of a canine artificial colonic mucus model for drug diffusion studies
- Ladda ner fulltext (pdf) av Development of a canine artificial colonic mucus model for drug diffusion studies
Benefits of combining supersaturating and solubilizing formulations - Is two better than one?
Ingår i International Journal of Pharmaceutics, 2024
Ingår i Journal of Medicinal Chemistry, s. 1008-1023, 2024
- DOI för Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections
- Ladda ner fulltext (pdf) av Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections
Ingår i European Journal of Pharmaceutical Sciences, 2024
- DOI för Development and characterization of solid lipid-based formulations (sLBFs) of ritonavir utilizing a lipolysis and permeation assay
- Ladda ner fulltext (pdf) av Development and characterization of solid lipid-based formulations (sLBFs) of ritonavir utilizing a lipolysis and permeation assay
Ingår i Journal of Computer-Aided Molecular Design, 2024
- DOI för Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison
- Ladda ner fulltext (pdf) av Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison
Ingår i European Journal of Pharmaceutical Sciences, 2024
- DOI för Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches
- Ladda ner fulltext (pdf) av Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches
Ingår i Journal of Colloid and Interface Science, s. 1253-1264, 2023
- DOI för Synergistic stabilization of emulsion gel by nanoparticles and surfactant enables 3D printing of lipid-rich solid oral dosage forms
- Ladda ner fulltext (pdf) av Synergistic stabilization of emulsion gel by nanoparticles and surfactant enables 3D printing of lipid-rich solid oral dosage forms
Ingår i Molecular Pharmaceutics, s. 451-460, 2023
- DOI för Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs
- Ladda ner fulltext (pdf) av Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs
Ingår i European Journal of Pharmaceutical Sciences, 2023
- DOI för Exploring the use of modified in vitro digestion assays for the evaluation of ritonavir loaded solid lipid-based formulations
- Ladda ner fulltext (pdf) av Exploring the use of modified in vitro digestion assays for the evaluation of ritonavir loaded solid lipid-based formulations
Intrinsic lipolysis rate for systematic design of lipid-based formulations
Ingår i Drug Delivery and Translational Research, s. 1288-1304, 2023
- DOI för Intrinsic lipolysis rate for systematic design of lipid-based formulations
- Ladda ner fulltext (pdf) av Intrinsic lipolysis rate for systematic design of lipid-based formulations
Evaluation in pig of an intestinal administration device for oral peptide delivery
Ingår i Journal of Controlled Release, s. 792-801, 2023
Ingår i International Journal of Pharmaceutics, 2023
Ingår i International Journal of Biological Macromolecules, 2023
- DOI för Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer
- Ladda ner fulltext (pdf) av Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer
Ingår i European Journal of Pharmaceutical Sciences, 2023
- DOI för Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs
- Ladda ner fulltext (pdf) av Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs
Membrane insertion mechanism of the caveola coat protein Cavin1
Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2022
- DOI för Membrane insertion mechanism of the caveola coat protein Cavin1
- Ladda ner fulltext (pdf) av Membrane insertion mechanism of the caveola coat protein Cavin1
Ingår i ACS Applied Materials and Interfaces, s. 21978-21988, 2022
- DOI för Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
- Ladda ner fulltext (pdf) av Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
Ingår i Molecular Pharmaceutics, s. 2564-2572, 2022
- DOI för Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model
- Ladda ner fulltext (pdf) av Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model
Ingår i Biomedicine and Pharmacotherapy, s. 112576-112576, 2022
- DOI för Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms
- Ladda ner fulltext (pdf) av Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms
Gastrointestinal mucus in dog: Physiological characteristics, composition, and structural properties
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 92-102, 2022
Ingår i Molecular Pharmaceutics, s. 200-212, 2022
- DOI för Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat
- Ladda ner fulltext (pdf) av Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat
Bioavailability of Celecoxib Formulated with Mesoporous Magnesium Carbonate: An In Vivo Evaluation
Ingår i Molecules, 2022
- DOI för Bioavailability of Celecoxib Formulated with Mesoporous Magnesium Carbonate: An In Vivo Evaluation
- Ladda ner fulltext (pdf) av Bioavailability of Celecoxib Formulated with Mesoporous Magnesium Carbonate: An In Vivo Evaluation
Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
Ingår i Molecular Pharmaceutics, s. 3922-3933, 2022
- DOI för Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
- Ladda ner fulltext (pdf) av Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
Ingår i International Journal of Pharmaceutics, 2022
UNGAP best practice for improving solubility data quality of orally administered drugs
Ingår i European Journal of Pharmaceutical Sciences, 2022
- DOI för UNGAP best practice for improving solubility data quality of orally administered drugs
- Ladda ner fulltext (pdf) av UNGAP best practice for improving solubility data quality of orally administered drugs
Ingår i Journal of Pharmaceutical Sciences, s. 175-184, 2022
- DOI för Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay
- Ladda ner fulltext (pdf) av Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay
Ingår i Molecular Pharmaceutics, s. 4079-4089, 2021
- DOI för Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations
- Ladda ner fulltext (pdf) av Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations
Ingår i Journal of Pharmaceutical Sciences, s. 239-250, 2021
- DOI för Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
- Ladda ner fulltext (pdf) av Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
3D-printing of solid lipid tablets from emulsion gels
Ingår i International Journal of Pharmaceutics, 2021
- DOI för 3D-printing of solid lipid tablets from emulsion gels
- Ladda ner fulltext (pdf) av 3D-printing of solid lipid tablets from emulsion gels
Physiological properties, composition and structural profiling of porcine gastrointestinal mucus
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 156-167, 2021
- DOI för Physiological properties, composition and structural profiling of porcine gastrointestinal mucus
- Ladda ner fulltext (pdf) av Physiological properties, composition and structural profiling of porcine gastrointestinal mucus
Synergistic Computational Modeling Approaches as Team Players in the Game of Solubility Predictions
Ingår i Journal of Pharmaceutical Sciences, s. 22-34, 2021
Ingår i Journal of Pharmaceutical Sciences, s. 176-185, 2021
- DOI för Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation
- Ladda ner fulltext (pdf) av Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation
Ingår i Journal of Pharmaceutical Sciences, s. 228-238, 2021
Ingår i Journal of Pharmaceutical Sciences, s. 217-227, 2021
Ingår i Journal of Pharmaceutical Sciences, s. 2-11, 2021
Ingår i Angewandte Chemie International Edition, s. 2069-2073, 2021
- DOI för TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica
- Ladda ner fulltext (pdf) av TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica
Ingår i Molecules, 2021
- DOI för Increasing the Transport of Celecoxib over a Simulated Intestine Cell Membrane Model Using Mesoporous Magnesium Carbonate
- Ladda ner fulltext (pdf) av Increasing the Transport of Celecoxib over a Simulated Intestine Cell Membrane Model Using Mesoporous Magnesium Carbonate
Ingår i ACS - Infectious Diseases, s. 2666-2685, 2021
- DOI för Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa
- Ladda ner fulltext (pdf) av Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa
Ingår i Molecular Pharmaceutics, s. 2254-2262, 2021
Ingår i Langmuir, s. 10200-10213, 2021
- DOI för Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine
- Ladda ner fulltext (pdf) av Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine
Ingår i International Journal of Pharmaceutics, 2021
Celebrating Women in the Pharmaceutical Sciences
Ingår i Molecular Pharmaceutics, s. 1487-1490, 2021
Ingår i Frontiers in Chemistry, 2020
- DOI för Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa
- Ladda ner fulltext (pdf) av Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa
Ingår i ADMET & DMPK, s. 176-179, 2020
- DOI för Strategies of solubility enhancement and perspectives in solubility measurements of pharmaceutical compounds
- Ladda ner fulltext (pdf) av Strategies of solubility enhancement and perspectives in solubility measurements of pharmaceutical compounds
Insights into Dissolution and Solution Chemistry of Multidrug Formulations of Antihypertensive Drugs
Ingår i Molecular Pharmaceutics, s. 4018-4028, 2020
Ingår i Pharmaceutics, 2020
- DOI för Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media
- Ladda ner fulltext (pdf) av Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media
Ingår i Pharmaceutics, 2020
- DOI för Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions
- Ladda ner fulltext (pdf) av Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions
Ingår i Pharmaceutics, 2020
- DOI för In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier
- Ladda ner fulltext (pdf) av In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier
Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties
Ingår i AAPS Journal, 2020
- DOI för Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties
- Ladda ner fulltext (pdf) av Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties
Ingår i Molecular Pharmaceutics, s. 3837-3844, 2020
- DOI för Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization
- Ladda ner fulltext (pdf) av Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization
Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations
Ingår i Pharmaceutical research, 2020
- DOI för Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations
- Ladda ner fulltext (pdf) av Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations
Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers
Ingår i Molecular Pharmaceutics, s. 4226-4240, 2020
- DOI för Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers
- Ladda ner fulltext (pdf) av Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers
Ingår i ACS Omega, s. 25733-25746, 2020
- DOI för Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions
- Ladda ner fulltext (pdf) av Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions
An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 21-29, 2020
- DOI för An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems
- Ladda ner fulltext (pdf) av An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems
Ingår i Molecular Pharmaceutics, s. 1458-1469, 2020
Ingår i Pharmaceutics, 2019
Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage
Ingår i Molecules, 2019
- DOI för Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage
- Ladda ner fulltext (pdf) av Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage
Ingår i AAPS PharmSciTech, 2019
- DOI för Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation
- Ladda ner fulltext (pdf) av Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation
Ingår i Journal of Controlled Release, s. 90-100, 2019
- DOI för Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?
- Ladda ner fulltext (pdf) av Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?
Ingår i Molecular Pharmaceutics, s. 4636-4650, 2019
Ingår i European Journal of Pharmaceutical Sciences, 2019
- DOI för Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
- Ladda ner fulltext (pdf) av Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?
Ingår i Journal of Pharmaceutical Sciences, s. 1765-1771, 2019
- DOI för Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?
- Ladda ner fulltext (pdf) av Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?
Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro
Ingår i Molecular Pharmaceutics, s. 921-930, 2019
- DOI för Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro
- Ladda ner fulltext (pdf) av Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro
Ingår i Journal of Pharmaceutical Sciences, s. 630-640, 2019
- DOI för Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection
- Ladda ner fulltext (pdf) av Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection
Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions
Ingår i Journal of Pharmaceutical Sciences, s. 252-259, 2019
- DOI för Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions
- Ladda ner fulltext (pdf) av Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions
Ingår i Journal of Pharmaceutical Sciences, s. 2-7, 2019
Automated assays for thermodynamic (equilibrium) solubility determination.
Ingår i Drug Discovery Today, s. 11-19, 2018
Ingår i AAPS Journal, 2018
Ingår i AAPS PharmSciTech, s. 2859-2865, 2018
- DOI för A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions
- Ladda ner fulltext (pdf) av A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions
Ingår i Molecular Pharmaceutics, s. 4733-4744, 2018
- DOI för Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations
- Ladda ner fulltext (pdf) av Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations
Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations
Ingår i Pharmaceutical research, 2018
- DOI för Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations
- Ladda ner fulltext (pdf) av Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations
Ingår i International Journal of Pharmaceutics, s. 515-521, 2018
Ingår i International Journal of Pharmaceutics, s. 183-190, 2017
Ingår i Journal of Physical Chemistry B, s. 10869-10881, 2017
- DOI för Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid
- Ladda ner fulltext (pdf) av Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid
Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)
Ingår i European Journal of Pharmaceutical Sciences, s. 70-76, 2017
Ingår i Pharmaceutical research, s. 1805-1816, 2017
- DOI för Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds
- Ladda ner fulltext (pdf) av Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds
Ingår i Journal of Controlled Release, s. 193-202, 2017
- DOI för Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways
- Ladda ner fulltext (pdf) av Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways
Ingår i Molecular Pharmaceutics, s. 4145-4153, 2017
- DOI för Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach
- Ladda ner fulltext (pdf) av Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach
Ingår i Molecular Pharmaceutics, s. 4161-4169, 2017
Tools for Early Prediction of Drug Loading in Lipid-Based Formulations
Ingår i Molecular Pharmaceutics, s. 251-261, 2016
Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®
Ingår i Journal of Pharmaceutical Sciences, s. 657-663, 2016
Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.
Ingår i Journal of Controlled Release, s. 172-182, 2016
Ingår i Journal of Pharmaceutical Sciences, s. 2864-2872, 2016
Understanding the Challenge of Beyond-Rule-of-5 Compounds Preface
Ingår i Advanced Drug Delivery Reviews, s. 1-5, 2016
Rapid determination of drug solubilization versus supersaturation in natural and digested lipids
Ingår i International Journal of Pharmaceutics, s. 164-174, 2016
Lipophilicity in Drug Development: Too Much or Not Enough?
Ingår i AAPS Journal, s. 1095-1100, 2016
Ingår i Langmuir, s. 12732-12740, 2016
- DOI för Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations
- Ladda ner fulltext (pdf) av Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations
Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate
Ingår i European Journal of Pharmaceutical Sciences, s. 468-474, 2016
Concomitant intake of alcohol may increase the absorption of poorly soluble drugs
Ingår i European Journal of Pharmaceutical Sciences, s. 12-20, 2015
- DOI för Concomitant intake of alcohol may increase the absorption of poorly soluble drugs
- Ladda ner fulltext (pdf) av Concomitant intake of alcohol may increase the absorption of poorly soluble drugs
Computational modeling to predict the functions and impact of drug transporters
Ingår i In silico pharmacology, 2015
- DOI för Computational modeling to predict the functions and impact of drug transporters
- Ladda ner fulltext (pdf) av Computational modeling to predict the functions and impact of drug transporters
Models for Predicting Drug Absorption From Oral Lipid-Based Formulations
Ingår i Current molecular biology reports, s. 141-147, 2015
- DOI för Models for Predicting Drug Absorption From Oral Lipid-Based Formulations
- Ladda ner fulltext (pdf) av Models for Predicting Drug Absorption From Oral Lipid-Based Formulations
Ingår i International Journal of Pharmaceutics, s. 312-317, 2015
- DOI för Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability
- Ladda ner fulltext (pdf) av Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability
Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid
Ingår i Pharmaceutical research, s. 578-589, 2015
- DOI för Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid
- Ladda ner fulltext (pdf) av Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid
Is the full potential of the biopharmaceutics classification system reached?
Ingår i European Journal of Pharmaceutical Sciences, s. 224-231, 2014
Experimental and Computational Prediction of Glass Transition Temperature of Drugs
Ingår i JOURNAL OF CHEMICAL INFORMATION AND MODELING, s. 3396-3403, 2014
Ingår i PLOS ONE, 2014
- DOI för Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis
- Ladda ner fulltext (pdf) av Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis
Pyridyl Benzamides as a Novel Class of Potent Inhibitors for the Kinetoplastid Trypanosoma brucei
Ingår i Journal of Medicinal Chemistry, s. 6393-6402, 2014
Computational predictions of glass-forming ability and crystallization tendency of drug molecules
Ingår i Molecular Pharmaceutics, s. 3123-3132, 2014
Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs
Ingår i European Journal of Pharmaceutical Sciences, s. 173-199, 2014
Ingår i Molecular Pharmaceutics, s. 2823-2848, 2013
Ingår i Toxicological Sciences, s. 328-343, 2013
- DOI för Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)
- Ladda ner fulltext (pdf) av Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)
Early drug development predictions of glass-forming ability and physical stability of drugs
Ingår i European Journal of Pharmaceutical Sciences, s. 323-332, 2013
- DOI för Early drug development predictions of glass-forming ability and physical stability of drugs
- Ladda ner fulltext (pdf) av Early drug development predictions of glass-forming ability and physical stability of drugs
Ingår i Bulletin Technique Gattefossé, s. 50-57, 2013
Ingår i Journal of Medicinal Chemistry, s. 2690-2694, 2013
Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients
Ingår i Pharmaceutical research, s. 3225-3237, 2013
- DOI för Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients
- Ladda ner fulltext (pdf) av Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients
Ingår i Pharmaceutical research, s. 411-426, 2012
Computational Prediction of CNS Drug Exposure Based on a Novel In Vivo Dataset
Ingår i Pharmaceutical research, s. 3131-3142, 2012
Ethanol Effects on Apparent Solubility of Poorly Soluble Drugs in Simulated Intestinal Fluid
Ingår i Molecular Pharmaceutics, s. 1942-1952, 2012
Ingår i Journal of Pharmaceutical Sciences, s. 3763-3772, 2011
Ingår i Molecular Pharmaceutics, s. 498-506, 2011
A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery
Ingår i Molecular pharmaceutics, s. 1478-1487, 2010
Dissolution Rate and Apparent Solubility of Poorly Soluble Drugs in Biorelevant Dissolution Media
Ingår i Molecular pharmaceutics, s. 1419-1430, 2010
Ingår i Drug metabolism reviews (Softcover ed.), s. 304-305, 2010
Ingår i European Journal of Pharmaceutical Sciences, s. 556-563, 2009
Ingår i Pharmaceutical research, s. 1816-1831, 2009
Ingår i Journal of Medicinal Chemistry, s. 5932-5942, 2008
Molecular characteristics for solid-state limited solubility
Ingår i Journal of Medicinal Chemistry, s. 3035-3039, 2008
Ingår i Journal of Medicinal Chemistry, s. 3275-3287, 2008
Poorly soluble marketed drugs display solvation limited solubility
Ingår i Journal of Medicinal Chemistry, s. 5858-5862, 2007
Ingår i Journal of Pharmacology and Experimental Therapeutics, s. 19-30, 2007
Photoinduced Formation of N2 Molecules in Ammonium Compounds
Ingår i Journal of Physical Chemistry A, s. 9662-9669, 2007
Contribution of solid-state properties to the aqueous solubility of drugs.
Ingår i Eur J Pharm Sci, s. 294-305, 2006
Prediction of ADMET Properties.
Ingår i ChemMedChem, s. 920-937, 2006
X-ray yield and selectively excited X-ray emission spectra of atenolol and nadolol.
Ingår i J Electr Spectr, s. 283-285, 2005
Computational models to predict aqueous drug solubility, permeability and intestinal absorption
Ingår i Expert opinion on drug metabolism & toxicology, s. 613-627, 2005
Theoretical predictions of drug absorption in drug discovery and development
Ingår i Clinical Pharmacokinetics, s. 877-899, 2002
Pickering emulsion gel enables 3D printing of lipid-rich solid oral dosage forms
Artiklar, forskningsöversikt
Contemporary formulation development for inhaled pharmaceuticals
Ingår i Journal of Pharmaceutical Sciences, s. 66-86, 2021
- DOI för Contemporary formulation development for inhaled pharmaceuticals
- Ladda ner fulltext (pdf) av Contemporary formulation development for inhaled pharmaceuticals
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 46-55, 2019
- DOI för Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning
- Ladda ner fulltext (pdf) av Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning
Ingår i International Journal of Pharmaceutics, s. 264-281, 2019
Ingår i European journal of pharmaceutics and biopharmaceutics, s. 101-114, 2019
Perspectives in solubility measurement and interpretation
Ingår i ADMET AND DMPK, s. 88-105, 2019
- DOI för Perspectives in solubility measurement and interpretation
- Ladda ner fulltext (pdf) av Perspectives in solubility measurement and interpretation
Ingår i International Journal of Pharmaceutics, s. 185-193, 2018
- DOI för Computational prediction of drug solubility in water-based systems: qualitative and quantitative approaches used in the current drug discovery and development setting
- Ladda ner fulltext (pdf) av Computational prediction of drug solubility in water-based systems: qualitative and quantitative approaches used in the current drug discovery and development setting
The Need for Restructuring the Disordered Science of Amorphous Drug Formulations
Ingår i Pharmaceutical Research, s. 1754-1772, 2017
- DOI för The Need for Restructuring the Disordered Science of Amorphous Drug Formulations
- Ladda ner fulltext (pdf) av The Need for Restructuring the Disordered Science of Amorphous Drug Formulations
Computational prediction of formulation strategies for beyond-rule-of-5 compounds
Ingår i Advanced Drug Delivery Reviews, s. 6-21, 2016
- DOI för Computational prediction of formulation strategies for beyond-rule-of-5 compounds
- Ladda ner fulltext (pdf) av Computational prediction of formulation strategies for beyond-rule-of-5 compounds
50 years of oral lipid-based formulations: Provenance, progress and future perspectives
Ingår i Advanced Drug Delivery Reviews, s. 167-194, 2016
Ingår i Therapeutic delivery, s. 935-959, 2015
Prediction of ADMET Properties
Ingår i ChemMedChem, s. 920-937, 2006
Kapitel i böcker, delar av antologi
How Physicochemical Properties of Drugs Affect Their Metabolism and Clearance
Ingår i New Horizons in Predictive Drug Metabolism and Pharmacokinetics, s. 1-26, Royal Society of Chemistry, 2016
Computational absorption prediction
Ingår i Drug bioavailability, s. 409-432, Wiley-VCH, 2008
Prediction of ADMET Properties
Ingår i Chemical Biology, s. 1003-1044, Wiley-VCH, 2007
Konferensbidrag
Advanced methodologies to study in vitro digestion of a lipid-loaded mesoporous drug carrier
Ingår i Preclinical Form and Formulation for Drug Discovery, Gordon Research Conference 2019, 2019
Synthesis of amorphous magnesium carbonate nanoparticles for biomedical applications
Ingår i Bioceramics 29 ISCM 2017, 2017
A new method that enables in situ measurement of drug release from complex carrier-mediated systems
Ingår i 6th FIP Pharmaceutical Sciences World Congress2017., 2017
Ingår i pION Fiber Optic Advanced Training Course. Uppsala, June 14-15, 2016., 2016
Diffusion controlled drug release from Mesoprous Magnesium Carbonate
2016