Maija-Leena Eloranta

Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment

Sayadi, Ahmed; Eloranta, Maija-Leena; Oparina, Nina Y.; Wallgren, Marcus et al.

Ingår i Journal of Autoimmunity, 2026

• DOI för Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment
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Innate immune cell subsets are enriched in synovial fluid of ACPA-negative rheumatoid arthritis and characterized by distinct type I IFN gene signatures

Argyriou, Alexandra; Wadsworth, Marc H.; Fienman, Joshua; Gonzalez-Sanchez, Ana Cristina et al.

Ingår i Annals of the Rheumatic Diseases, s. 265-275, 2026

• DOI för Innate immune cell subsets are enriched in synovial fluid of ACPA-negative rheumatoid arthritis and characterized by distinct type I IFN gene signatures
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Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Eloranta, Maija-Leena; Nygren, Peter; Larsson, Rolf; Loskog, Angelica et al.

Ingår i Scientific Reports, 2026

• DOI för Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Wiley, Mandi M.; Radziszewski, Marcin; Khatri, Bhuwan; Joachims, Michelle L. et al.

Ingår i Annals of the Rheumatic Diseases, s. 1512-1527, 2025

• DOI för Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes

Vestin, Holme; Oparina, Nina Y.; Eloranta, Maija-Leena; Frodlund, Martina et al.

Ingår i RMD Open, 2025

• DOI för Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes
• Ladda ner fulltext (pdf) av Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes

Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment

Sayadi, Ahmed; Eloranta, Maija-Leena; Oparina, Nina Y.; Wallgren, Marcus et al.

Ingår i Journal of Autoimmunity, 2026

• DOI för Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment
• Ladda ner fulltext (pdf) av Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment

Innate immune cell subsets are enriched in synovial fluid of ACPA-negative rheumatoid arthritis and characterized by distinct type I IFN gene signatures

Argyriou, Alexandra; Wadsworth, Marc H.; Fienman, Joshua; Gonzalez-Sanchez, Ana Cristina et al.

Ingår i Annals of the Rheumatic Diseases, s. 265-275, 2026

• DOI för Innate immune cell subsets are enriched in synovial fluid of ACPA-negative rheumatoid arthritis and characterized by distinct type I IFN gene signatures
• Ladda ner fulltext (pdf) av Innate immune cell subsets are enriched in synovial fluid of ACPA-negative rheumatoid arthritis and characterized by distinct type I IFN gene signatures

Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Eloranta, Maija-Leena; Nygren, Peter; Larsson, Rolf; Loskog, Angelica et al.

Ingår i Scientific Reports, 2026

• DOI för Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Wiley, Mandi M.; Radziszewski, Marcin; Khatri, Bhuwan; Joachims, Michelle L. et al.

Ingår i Annals of the Rheumatic Diseases, s. 1512-1527, 2025

• DOI för Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes

Vestin, Holme; Oparina, Nina Y.; Eloranta, Maija-Leena; Frodlund, Martina et al.

Ingår i RMD Open, 2025

• DOI för Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes
• Ladda ner fulltext (pdf) av Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes

B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Hedenstedt, Anna; Reid, Sarah; Sayadi, Ahmed; Eloranta, Maija-Leena et al.

Ingår i Lupus Science and Medicine, 2023

• DOI för B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

2022 EULAR points to consider for the measurement, reporting and application of IFN-I pathway activation assays in clinical research and practice

Rodriguez-Carrio, Javier; Burska, Agata; Conaghan, Philip G.; Dik, Willem A. et al.

Ingår i Annals of the Rheumatic Diseases, s. 754-762, 2023

• DOI för 2022 EULAR points to consider for the measurement, reporting and application of IFN-I pathway activation assays in clinical research and practice

Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA

Dahlqvist, Johanna; Ekman, Diana; Sennblad, Bengt; Kozyrev, Sergey V. et al.

Ingår i Rheumatology, s. 3461-3470, 2022

• DOI för Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
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Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Lundtoft, Christian; Sjöwall, Christopher; Rantapää‐Dahlqvist, Solbritt; Bengtsson, Anders A. et al.

Ingår i Arthritis & Rheumatology, s. 1842-1850, 2022

• DOI för Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome
• Ladda ner fulltext (pdf) av Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Lundtoft, Christian; Pucholt, Pascal; Martin, Myriam; Bianchi, Matteo et al.

Ingår i Arthritis & Rheumatology, s. 1440-1450, 2022

• DOI för Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
• Ladda ner fulltext (pdf) av Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease

Yavuz, Sule; Pucholt, Pascal; Sandling, Johanna K.; Bianchi, Matteo et al.

Ingår i Lupus Science and Medicine, 2022

• DOI för Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease
• Ladda ner fulltext (pdf) av Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease

Genome-wide association study identifies Sjogren's risk loci with functional implications in immune and glandular cells

Khatri, Bhuwan; Tessneer, Kandice L.; Rasmussen, Astrid; Aghakhanian, Farhang et al.

Ingår i Nature Communications, 2022

• DOI för Genome-wide association study identifies Sjogren's risk loci with functional implications in immune and glandular cells
• Ladda ner fulltext (pdf) av Genome-wide association study identifies Sjogren's risk loci with functional implications in immune and glandular cells

Different chest HRCT scan protocols change the extent of ground glass opacities

Emilsson, Össur Ingi; Dessle, Angelica; Johansson, Henrik; Adeli, Shamisa et al.

Ingår i BMC Pulmonary Medicine, 2022

• DOI för Different chest HRCT scan protocols change the extent of ground glass opacities
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Contributions of de novo variants to systemic lupus erythematosus

Carlsson Almlöf, Jonas; Nystedt, Sara; Mechtidou, Aikaterini; Leonard, Dag et al.

Ingår i European Journal of Human Genetics, s. 184-193, 2021

• DOI för Contributions of de novo variants to systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Contributions of de novo variants to systemic lupus erythematosus

DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Norheim, Katrine Braekke; Johnsen, Svein Joar Auglaend et al.

Ingår i Frontiers in Immunology, 2021

• DOI för DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome
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C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

Enocsson, Helena; Gullstrand, Birgitta; Eloranta, Maija-Leena; Wetterö, Jonas et al.

Ingår i Frontiers in Immunology, 2021

• DOI för C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205
• Ladda ner fulltext (pdf) av C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

Sandling, Johanna K.; Pucholt, Pascal; Hultin-Rosenberg, Lina; Farias, Fabiana H. G. et al.

Ingår i Annals of the Rheumatic Diseases, s. 109-117, 2021

• DOI för Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
• Ladda ner fulltext (pdf) av Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus

Enocsson, Helena; Wetterö, Jonas; Eloranta, Maija-Leena; Gullstrand, Birgitta et al.

Ingår i Frontiers in Immunology, 2021

• DOI för Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus
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High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Morris, David et al.

Ingår i Annals of the Rheumatic Diseases, s. 363-369, 2020

• DOI för High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
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Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero

Hedlund, Malin; Thorlacius, Gudny Ella; Ivanchenko, Margarita; Ottosson, Vijole et al.

Ingår i RMD Open, 2020

• DOI för Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
• Ladda ner fulltext (pdf) av Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero

The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells

Hjorton, Karin; Hagberg, Niklas; Pucholt, Pascal; Eloranta, Maija-Leena et al.

Ingår i Arthritis Research & Therapy, 2020

• DOI för The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells
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Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists

Berggren, Olof; Pucholt, Pascal; Amcoff, Cane; Rönnblom, Lars et al.

Ingår i Scandinavian Journal of Immunology, 2020

• DOI för Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists
• Ladda ner fulltext (pdf) av Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists

Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling

Lundtoft, Christian; Pucholt, Pascal; Imgenberg-Kreuz, Juliana; Carlsson Almlöf, Jonas et al.

Ingår i PLOS Genetics, 2020

• DOI för Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling
• Ladda ner fulltext (pdf) av Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling

Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus

Almlöf, Jonas Carlsson; Nystedt, Sara; Leonard, Dag; Eloranta, Maija-Leena et al.

Ingår i Human Genetics, s. 141-150, 2019

• DOI för Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus

A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-a levels and high serum interferogenic activity

Bolin, Karin; Eloranta, Maija-Leena; Kozyrev, Sergey V.; Dahlqvist, Johanna et al.

Ingår i Rheumatology, s. 918-919, 2019

• DOI för A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-a levels and high serum interferogenic activity

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Odqvist, Lina; Jevnikar, Zala; Riise, Rebecca; Oberg, Lisa et al.

Ingår i Annals of the Rheumatic Diseases, s. 1363-1370, 2019

• DOI för Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

Farias, Fabiana H. G.; Dahlqvist, Johanna; Kozyrev, Sergey V.; Leonard, Dag et al.

Ingår i European Journal of Human Genetics, s. 432-441, 2019

• DOI för A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
• Ladda ner fulltext (pdf) av A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Leonard, Dag; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 736-743, 2018

• DOI för DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
• Ladda ner fulltext (pdf) av DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

Transcription profiling of peripheral B cells in antibody-positive primary Sjogren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Bjork, A.; Nordlund, J. et al.

Ingår i Scandinavian Journal of Immunology, 2018

• DOI för Transcription profiling of peripheral B cells in antibody-positive primary Sjogren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature
• Ladda ner fulltext (pdf) av Transcription profiling of peripheral B cells in antibody-positive primary Sjogren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature

T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus

Houtman, Miranda; Shchetynsky, Klementy; Chemin, Karine; Hensvold, Aase Haj et al.

Ingår i Journal of Autoimmunity, s. 28-38, 2018

• DOI för T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus
• Ladda ner fulltext (pdf) av T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus

Interleukin-22 and associated genes are targets of microRNAs dysregulated

Tarn, Jessica R.; Nordmark, Gunnel; Gillespie, Colin; Al-Ali, Shereen et al.

Ingår i Clinical and Experimental Rheumatology, 2018

Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

Leonard, Dag; Svenungsson, Elisabet; Dahlqvist, Johanna; Alexsson, Andrei et al.

Ingår i Annals of the Rheumatic Diseases, s. 1063-1069, 2018

• DOI för Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
• Ladda ner fulltext (pdf) av Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

Hagberg, Niklas; Joelsson, Martin; Leonard, Dag; Reid, Sarah et al.

Ingår i Annals of the Rheumatic Diseases, s. 1070-1077, 2018

• DOI för The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE
• Ladda ner fulltext (pdf) av The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor

Hjorton, Karin; Hagberg, Niklas; Israelsson, Elisabeth; Jinton, Lisa et al.

Ingår i Arthritis Research & Therapy, 2018

• DOI för Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor
• Ladda ner fulltext (pdf) av Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor

The risk allele A of rs200395694 associated with SLE in Swedish patients affects on MEF2D gene regulation and alternative splicing

Abramov, Sergei; Kozyrev, Sergey V.; Farias, Fabiana H. G.; Dahlqvist, Johanna et al.

Ingår i Human Gene Therapy, 2018

ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

Bremer, Hanna D.; Landegren, Nils; Sjöberg, Ronald; Hallgren, Åsa et al.

Ingår i Scientific Reports, 2018

• DOI för ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
• Ladda ner fulltext (pdf) av ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

Interferon-α coincides with suppressed levels of pentraxin-3 (PTX3) in systemic lupus erythematosus and regulates leucocyte PTX3 in vitro

Wirestam, Lina; Enocsson, Helena; Skogh, Thomas; Eloranta, Maija-Leena et al.

Ingår i Clinical and Experimental Immunology, s. 83-91, 2017

• DOI för Interferon-α coincides with suppressed levels of pentraxin-3 (PTX3) in systemic lupus erythematosus and regulates leucocyte PTX3 in vitro

Novel risk genes for systemic lupus erythematosus predicted by random forest classification

Carlsson Almlöf, Jonas; Alexsson, Andrei; Imgenberg-Kreuz, Juliana; Sylwan, Lina et al.

Ingår i Scientific Reports, 2017

• DOI för Novel risk genes for systemic lupus erythematosus predicted by random forest classification
• Ladda ner fulltext (pdf) av Novel risk genes for systemic lupus erythematosus predicted by random forest classification

Type I IFN System Activation In Newborns Exposed To ANTI-RO/SSA Autoantibodies In Utero

Wahren, M.; Hedlund, M.; Thorlacius, G. E.; Ivanchenko, M. et al.

Ingår i Annals of the Rheumatic Diseases, s. 182-182, 2017

• DOI för Type I IFN System Activation In Newborns Exposed To ANTI-RO/SSA Autoantibodies In Utero

High Genetic Risk Score Is Associated with Increased Organ Damage in SLE

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Sandling, Johanna K. et al.

Ingår i Arthritis & Rheumatology, 2017

Type I IFN System Activation In Newborns Exposed To Anti-Ro/Ssa Autoantibodies In Utero

Hedlund, Malin; Thorlacius, Gudny Ella; Ivanchenko, Margarita; Kyriakidis, Nikolaos et al.

Ingår i Annals of the Rheumatic Diseases, 2017

• DOI för Type I IFN System Activation In Newborns Exposed To Anti-Ro/Ssa Autoantibodies In Utero

Treatment-Associated DNA Methylation Patterns in Systemic Lupus Erythematosus

Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Leonard, Dag; Nordmark, Gunnel et al.

Ingår i Arthritis & Rheumatology, 2017

Expression Patterns of Interferon Induced Genes in Newborns Exposed to Ro/SSA Autoantibodies in Utero

Thorlacius, Gudny Ella; Hedlund, Malin; Ivanchenko, Margarita; Ottosson, Vijole et al.

Ingår i Arthritis & Rheumatology, 2017

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

Li, He; Reksten, Tove Ragna; Ice, John A.; Kelly, Jennifer A. et al.

Ingår i PLOS Genetics, 2017

• DOI för Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons
• Ladda ner fulltext (pdf) av Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype

Berggren, Olof; Hagberg, Niklas; Alexsson, Andrei; Weber, Gert et al.

Ingår i PLOS ONE, 2017

• DOI för Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype
• Ladda ner fulltext (pdf) av Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype

Activated Plasmacytoid Dendritic Cells (PDCS) Alter The Composition of The Blood B Cell Subsets

Berggren, Olof; Rönnblom, Lars; Eloranta, Maija-Leena

Ingår i Annals of the Rheumatic Diseases, s. 179-179, 2016

• DOI för Activated Plasmacytoid Dendritic Cells (PDCS) Alter The Composition of The Blood B Cell Subsets

The Effect of Hydroxychloroquine and IRAK4 Inhibition on The IFN-A and TNF-A Production Induced by Sle Related Immune Complexes

Hjorton, Karin; Hagberg, Niklas; Berggren, Olof; Mo, J. et al.

Ingår i Annals of the Rheumatic Diseases, s. 277-277, 2016

• DOI för The Effect of Hydroxychloroquine and IRAK4 Inhibition on The IFN-A and TNF-A Production Induced by Sle Related Immune Complexes

The effect of PTPN22 Gene Variant R620W on the Type I Interferon Production Stimulated by Different TLR7 Agonists: Comment on Article by Wang et al (pages 2403-2414)

Berggren, Olof; Rönnblom, Lars; Eloranta, Maija-Leena

Ingår i Arthritis & Rheumatology, s. 1045-1045, 2016

• DOI för The effect of PTPN22 Gene Variant R620W on the Type I Interferon Production Stimulated by Different TLR7 Agonists: Comment on Article by Wang et al (pages 2403-2414)

Cause and consequences of the activated type I interferon system in SLE

Eloranta, Maija-Leena; Rönnblom, Lars

Ingår i Journal of Molecular Medicine, s. 1103-1110, 2016

• DOI för Cause and consequences of the activated type I interferon system in SLE
• Ladda ner fulltext (pdf) av Cause and consequences of the activated type I interferon system in SLE

Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 1728-1734, 2016

• DOI för Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Ingår i Annals of the Rheumatic Diseases, s. 2029-2036, 2016

• DOI för Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes
• Ladda ner fulltext (pdf) av Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.

Folkersen, Lasse; Brynedal, Boel; Diaz-Gallo, Lina Marcela; Ramsköld, Daniel et al.

Ingår i Molecular Medicine, s. 322-328, 2016

• DOI för Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.
• Ladda ner fulltext (pdf) av Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.

Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Cavalli, Marco; Pan, Gang; Nord, Helena; Wallerman, Ola et al.

Ingår i Human Genetics, s. 485-497, 2016

• DOI för Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression
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Functional Anti-CD94/NKG2A and Anti-CD94/NKG2C Autoantibodies in Patients With Systemic Lupus Erythematosus

Hagberg, Niklas; Theorell, Jakob; Hjorton, Karin; Spee, Pieter et al.

Ingår i ARTHRITIS & RHEUMATOLOGY, s. 1000-1011, 2015

• DOI för Functional Anti-CD94/NKG2A and Anti-CD94/NKG2C Autoantibodies in Patients With Systemic Lupus Erythematosus

Genome-Wide Analysis of DNA Methylation Profiles in Multiple Tissues in Primary Sjogren's Syndrome

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Carlsson Almlöf, Jonas; Omdal, Roald et al.

Ingår i Scandinavian Journal of Immunology, s. 412-412, 2015

Identification of Novel Sjogren's Syndrome Risk Loci in the Regions of TNFAIP3 and PRDM1

Lessard, Christopher J.; Li, He; Ice, John; Adrianto, Indra et al.

Ingår i Arthritis & Rheumatology, 2015

• DOI för Identification of Novel Sjogren's Syndrome Risk Loci in the Regions of TNFAIP3 and PRDM1

Hypomethylation in Enhancer and Promoter Regions of Interferon Regulated Genes in Multiple Tissues Is Associated with Primary Sjogren's Syndrome

Imgenberg-Kreuz, Juliana; Sandling, Johanna K.; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Ingår i Arthritis & Rheumatology, 2015

• DOI för Hypomethylation in Enhancer and Promoter Regions of Interferon Regulated Genes in Multiple Tissues Is Associated with Primary Sjogren's Syndrome

Genome-wide analysis of DNA methylation in systemic lupus erythematosus

Sandling, Johanna K.; Imgenberg-Kreuz, Juliana; Carlsson Almlöf, Jonas; Nordmark, Gunnel et al.

Ingår i Clinical and Experimental Rheumatology, 2015

IFN-α production by plasmacytoid dendritic cell associations with polymorphisms in gene loci related to autoimmune and inflammatory diseases

Berggren, Olof; Alexsson, Andrei; Morris, David; Tandre, Karolina et al.

Ingår i Human Molecular Genetics, s. 3571-3581, 2015

• DOI för IFN-α production by plasmacytoid dendritic cell associations with polymorphisms in gene loci related to autoimmune and inflammatory diseases

An NFKB1 gene promoter polymorphism is associated with primary Sjogren's syndrome

Nordmark, Gunnel; Vasaitis, Lilian; Theander, E.; Kvarnstrom, M. et al.

Ingår i Scandinavian Journal of Rheumatology, s. 87-88, 2014

High-Throughput Sequencing of 219 Candidate Genes for Identification of SLE-Associated Risk Variants

Farias, Fabiana; Wilbe, Maria; Dahlqvist, Johanna; Leonard, Dag et al.

Ingår i Arthritis & Rheumatology, 2014

Effect of single-nucleotide polymorphisms on type I interferon production by plasmacytoid dendritic cells stimulated with SLE-associated immune complexes

Berggren, Olof; Alexsson, Andrei; Tandre, Karolina; Syvanen, A-C et al.

Ingår i Scandinavian Journal of Rheumatology, s. 92-92, 2014

Activated T cells enhance interferon-alpha production by plasmacytoid dendritic cells stimulated by RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Scandinavian Journal of Rheumatology, s. 88-89, 2014

Genome-Wide DNA Methylation Analysis of CD19+B Cells in Primary Sjogren's Syndrome

Nordmark, Gunnel; Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Nordlund, Jessica et al.

Ingår i Arthritis & Rheumatology, 2014

Activated SLE-T Cells Enhance the Interferon-Alpha Production By Plasmacytoid Dendritic Cells Stimulated By RNA-IC

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Arthritis & Rheumatology, 2014

Serum C-reactive protein (CRP) associates with lupus disease activity in the absence of measurable interferon alpha and a CRP gene variant

Enocsson, Helena; Sjöwall, Christopher; Kastbom, Alf; Skogh, Thomas et al.

Ingår i Arthritis & rheumatology, s. 1568-1573, 2014

• DOI för Serum C-reactive protein (CRP) associates with lupus disease activity in the absence of measurable interferon alpha and a CRP gene variant

Brief Report: Interferon-α Induction and Detection of Anti-Ro, Anti-La, Anti-Sm, and Anti-RNP Autoantibodies by Autoantigen Microarray Analysis in Juvenile Dermatomyositis

Balboni, Imelda; Niewold, Timothy B; Morgan, Gabrielle; Limb, Cindy et al.

Ingår i Arthritis and Rheumatism, s. 2424-2429, 2013

• DOI för Brief Report: Interferon-α Induction and Detection of Anti-Ro, Anti-La, Anti-Sm, and Anti-RNP Autoantibodies by Autoantigen Microarray Analysis in Juvenile Dermatomyositis

Dual role of CpG-stimulated B cells in the regulation of dendritic cells: comment on the article by Berggren et al Reply

Eloranta, Maija-Leena; Rönnblom, Lars

Ingår i Arthritis and Rheumatism, s. 2216, 2013

• DOI för Dual role of CpG-stimulated B cells in the regulation of dendritic cells: comment on the article by Berggren et al Reply

Two rare disease-associated tyk2 variants are catalytically impaired but signaling competent

Li, Zhi; Gakovic, Milica; Ragimbeau, Josiane; Eloranta, Maija-Leena et al.

Ingår i Journal of Immunology, s. 2335-2344, 2013

• DOI för Two rare disease-associated tyk2 variants are catalytically impaired but signaling competent

Disease Mechanisms in RheumatologyTools and Pathways: Plasmacytoid Dendritic Cells and Their Role in AutoimmuneRheumatic Diseases

Eloranta, Maija-Leena; Alm, Gunnar V; Rönnblom, Lars

Ingår i Arthritis and Rheumatism, s. 853-863, 2013

• DOI för Disease Mechanisms in RheumatologyTools and Pathways: Plasmacytoid Dendritic Cells and Their Role in AutoimmuneRheumatic Diseases

Anti-NKG2A autoantibodies in a patient with systemic lupus erythematosus

Hagberg, Niklas; Theorell, Jakob; Eloranta, Maija-Leena; Pascal, Veronique et al.

Ingår i Rheumatology, s. 1818-1823, 2013

• DOI för Anti-NKG2A autoantibodies in a patient with systemic lupus erythematosus

NCR3/NKp30 Contributes to Pathogenesis in Primary Sjögren's Syndrome

Rusakiewicz, Sylvie; Nocturne, Gaetane; Lazure, Thierry; Semeraro, Michaela et al.

Ingår i Science Translational Medicine, 2013

• DOI för NCR3/NKp30 Contributes to Pathogenesis in Primary Sjögren's Syndrome

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

Lessard, Christopher J; Li, He; Adrianto, Indra; Ice, John A et al.

Ingår i Nature Genetics, s. 1284-1292, 2013

• DOI för Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE

Stone, R. C.; Du, P.; Feng, D.; Dhawan, K. et al.

Ingår i PLOS ONE, s. 54487, 2013

• DOI för RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE
• Ladda ner fulltext (pdf) av RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE

Association of genes in the NF-κB pathway with antibody positive primary Sjögren's syndrome

Nordmark, Gunnel; Wang, Chuan; Vasaitis, Lilian; Eriksson, Per et al.

Ingår i Scandinavian Journal of Immunology, s. 447-454, 2013

• DOI för Association of genes in the NF-κB pathway with antibody positive primary Sjögren's syndrome

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer L; Wahlberg, Per; Busche, Stephan et al.

Ingår i Genome Biology, 2013

• DOI för Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility

Wang, Chuan; Ahlford, Annika; Laxman, Navya; Nordmark, Gunnel et al.

Ingår i Genes and Immunity, s. 217-222, 2013

• DOI för Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
• Ladda ner fulltext (pdf) av Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility

Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

Wang, Chuan; Ahlford, Annika; Järvinen, Tiina M; Nordmark, Gunnel et al.

Ingår i European Journal of Human Genetics, s. 994-999, 2013

• DOI för Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis

Bolin, Karin; Sandling, Johanna K; Zickert, Agneta; Jönsen, Andreas et al.

Ingår i PLOS ONE, 2013

• DOI för Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis
• Ladda ner fulltext (pdf) av Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis

Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4

Wang, Chuan; Sandling, Johanna K; Hagberg, Niklas; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 96-103, 2013

• DOI för Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4

The NKp30/B7H6 Axis Contributes To Pathogenesis In Primary Sjogren's Syndrome.

Nocturne, Gaetane; Rusakiewicz, Sylvie; Sene, Damien; Nordmark, Gunnel et al.

Ingår i Arthritis and Rheumatism, 2013

Systemic Lupus Erythematosus Immune Complexes Increase the Expression of SLAM Family Members CD319 (CRACC) and CD229 (LY-9) on Plasmacytoid Dendritic Cells and CD319 on CD56(dim) NK Cells

Hagberg, Niklas; Theorell, Jakob; Schlums, Heinrich; Eloranta, Maija-Leena et al.

Ingår i Journal of Immunology, s. 2989-2998, 2013

• DOI för Systemic Lupus Erythematosus Immune Complexes Increase the Expression of SLAM Family Members CD319 (CRACC) and CD229 (LY-9) on Plasmacytoid Dendritic Cells and CD319 on CD56(dim) NK Cells

Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

Leonard, Dag; Svenungsson, Elisabet; Sandling, Johanna K; Berggren, Olof et al.

Ingår i Circulation, s. 255-263, 2013

• DOI för Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

On the Origin of the Type I Interferon Activity in Rheumatoid Arthritis

de Jong, T. D.; Vosslamber, S.; Eloranta, Maija-Leena; Rönnblom, Lars et al.

Ingår i Annals of the Rheumatic Diseases, 2013

• DOI för On the Origin of the Type I Interferon Activity in Rheumatoid Arthritis

Coronary Heart Disease in Systemic Lupus Erythematosus is Associated with Interferon Regulatory Factor 8 Gene Variants

Leonard, Dag; Svenungsson, E.; Sandling, J. K.; Berggren, Olof et al.

Ingår i Annals of the Rheumatic Diseases, s. 270-270, 2013

• DOI för Coronary Heart Disease in Systemic Lupus Erythematosus is Associated with Interferon Regulatory Factor 8 Gene Variants

SLE immune complexes upregulate the expression of slamf7 (cd319) on plasmacytoid dendritic cells

Hagberg, Niklas; Theorell, Jakob; Alm, Gunnar V.; Eloranta, Maija-Leena et al.

Ingår i Annals of the Rheumatic Diseases, 2012

• DOI för SLE immune complexes upregulate the expression of slamf7 (cd319) on plasmacytoid dendritic cells

Autoantibodies associated with RNA are more enriched than anti-dsDNA antibodies in circulating immune complexes in SLE

Åhlin, Erik; Mathsson, Linda; Eloranta, Maija-Leena; Jonsdottir, Thorunn et al.

Ingår i Lupus, s. 586-595, 2012

• DOI för Autoantibodies associated with RNA are more enriched than anti-dsDNA antibodies in circulating immune complexes in SLE

Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons

Stone, Rivka C; Feng, Di; Deng, Jing; Singh, Sukhwinder et al.

Ingår i Arthritis and Rheumatism, s. 788-798, 2012

• DOI för Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons

B lymphocytes enhance the interferon-α production by plasmacytoid dendritic cells

Berggren, Olof; Hagberg, Niklas; Weber, Gert; Alm, Gunnar V et al.

Ingår i Arthritis and Rheumatism, s. 3409-3419, 2012

• DOI för B lymphocytes enhance the interferon-α production by plasmacytoid dendritic cells

On the Origin of the Type I Interferon Signature in Rheumatoid Arthritis

de Jong, T. D.; Vosslamber, Saskia; Eloranta, Maija-Leena; Rönnblom, Lars et al.

Ingår i Arthritis and Rheumatism, 2012

Systemic Lupus Erythematosus Immune Complexes Upregulate the Expression of CD319 and CD229 On Plasmacytoid Dendritic Cells

Hagberg, Niklas; Theorell, Jakob; Alm, Gunnar V.; Eloranta, Maija-Leena et al.

Ingår i Arthritis and Rheumatism, 2012

Genetic Variation in the NCR3 Locus Is Associated with Anti-SSA/SSB Positive Primary Sjogren's Syndrome in Scandinavian Samples

Nordmark, Gunnel; Eloranta, Maija-Leena; Eriksson, Per; Theander, Elke et al.

Ingår i Arthritis and Rheumatism, 2012

Variation of Interferon-Alpha Production in Healthy Individuals and Association with Autoimmune Susceptibility Genes

Berggren, Olof; Alexsson, Andrei; Alm, Gunnar V.; Syvanen, Ann-Christine et al.

Ingår i Arthritis and Rheumatism, 2012

IFN-α Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1β and LFA-1

Hagberg, Niklas; Berggren, Olof; Leonard, Dag; Weber, Gert et al.

Ingår i Journal of Immunology, s. 5085-5094, 2011

• DOI för IFN-α Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1β and LFA-1

Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

Jonsen, Andreas; Nilsson, Sara C; Ahlqvist, Emma; Svenungsson, Elisabet et al.

Ingår i Arthritis Research & Therapy, 2011

• DOI för Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus
• Ladda ner fulltext (pdf) av Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome

Nordmark, Gunnel; Kristjansdottir, Gudlaug; Theander, E.; Appel, S. et al.

Ingår i Genes and Immunity, s. 100-109, 2011

• DOI för Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE

Sandling, Johanna K.; Garnier, Sophie; Sigurdsson, Snaevar; Wang, Chuan et al.

Ingår i European Journal of Human Genetics, s. 479-484, 2011

• DOI för A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE

Effects of high mobility group box protein-1, interleukin-1β, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures

Ley, Cecilia; Svala, Emilia; Nilton, Anna; Lindahl, Anders et al.

Ingår i Connective Tissue Research, s. 290-300, 2011

• DOI för Effects of high mobility group box protein-1, interleukin-1β, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures

Type I interferon system activation and association with disease manifestations in systemic sclerosis

Eloranta, Maija-Leena; Franck-Larsson, Karin; Lövgren, Tanja; Kalamajski, Sebastian et al.

Ingår i Annals of the Rheumatic Diseases, s. 1396-1402, 2010

• DOI för Type I interferon system activation and association with disease manifestations in systemic sclerosis

Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus

Feng, Di; Stone, Rivka C.; Eloranta, Maija-Leena; Sangster-Guity, Niquiche et al.

Ingår i Arthritis and Rheumatism, s. 562-573, 2010

• DOI för Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus

C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

Lood, Christian; Gullstrand, Birgitta; Truedsson, Lennart; Olin, Anders I. et al.

Ingår i Arthritis and Rheumatism, s. 3081-3090, 2009

• DOI för C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

Interferon-alpha Mediates Suppression of C-Reactive Protein Explanation for Muted C-Reactive Protein Response in Lupus Flares?

Enocsson, Helena; Sjöwall, Christopher; Skogh, Thomas; Eloranta, Maija-Leena et al.

Ingår i Arthritis and Rheumatism, s. 3755-3760, 2009

• DOI för Interferon-alpha Mediates Suppression of C-Reactive Protein Explanation for Muted C-Reactive Protein Response in Lupus Flares?

Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE

Isaksson, Magnus; Ardesjö, Brita; Rönnblom, Lars; Kämpe, Olle et al.

Ingår i European Journal of Immunology, s. 2925-2935, 2009

• DOI för Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE

Interleukin-6 and high mobility group box protein-1 in synovial membranes and osteochondral fragments in equine osteoarthritis

Ley, Cecilia; Ekman, S.; Ronéus, B.; Eloranta, Maija-Leena

Ingår i Research in Veterinary Science, s. 490-497, 2009

• DOI för Interleukin-6 and high mobility group box protein-1 in synovial membranes and osteochondral fragments in equine osteoarthritis

Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells

Eloranta, Maija-Leena; Lövgren, Tanja; Finke, Doreen; Mathsson, Linda et al.

Ingår i Arthritis and Rheumatism, s. 2418-2427, 2009

• DOI för Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells

Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome

Nordmark, Gunnel; Kristjansdottir, Gudlaug; Theander, E.; Eriksson, P. et al.

Ingår i Genes and Immunity, s. 68-76, 2009

• DOI för Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome

Increased proportion of CD56bright natural killer cells in active and inactive systemic lupus erythematosus

Schepis, Danika; Gunnarsson, Iva; Eloranta, Maija-Leena; Lampa, Jon et al.

Ingår i Immunology, s. 140-6, 2009

• DOI för Increased proportion of CD56bright natural killer cells in active and inactive systemic lupus erythematosus

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

Espinosa, Alexander; Dardalhon, Valerie; Brauner, Susanna; Ambrosi, Aurelie et al.

Ingår i Journal of Experimental Medicine, s. 1661-1671, 2009

• DOI för Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

Sigurdsson, Snaevar; Göring, Harald H. H.; Kristjansdottir, Gudlaug; Milani, Lili et al.

Ingår i Human Molecular Genetics, s. 872-881, 2008

• DOI för Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

Sigurdsson, Snaevar; Nordmark, Gunnel; Garnier, Sophie; Grundberg, Elin et al.

Ingår i Human Molecular Genetics, s. 2868-2876, 2008

• DOI för A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies

Strandberg, Linn; Ambrosi, Aurelie; Espinosa, Alexander; Ottosson, Lars et al.

Ingår i Journal of Clinical Immunology, s. 220-31, 2008

• DOI för Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies

A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti-Jo-1 or anti-Ro 52/anti-Ro 60 autoantibodies

Eloranta, Maija-Leena; Helmers, Sevim Barbasso; Ulfgren, Ann-Kristin; Rönnblom, Lars et al.

Ingår i Arthritis and Rheumatism, s. 3112-3124, 2007

• DOI för A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti-Jo-1 or anti-Ro 52/anti-Ro 60 autoantibodies

Interleukin-6 and tumour necrosis factor in synovial fluid from horses with carpal joint pathology

Ley, Cecilia; Ekman, S.; Elmén, A.; Nilsson, G. et al.

Ingår i Journal of Veterinary Medicine A, s. 346-351, 2007

• DOI för Interleukin-6 and tumour necrosis factor in synovial fluid from horses with carpal joint pathology

Induction of interferon-α by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA

Lövgren, Tanja; Eloranta, Maija-Leena; Kastner, Berthold; Wahren-Herlenius, Marie et al.

Ingår i Arthritis and Rheumatism, s. 1917-1927, 2006

• DOI för Induction of interferon-α by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA

Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanism

Båve, Ullvi; Nordmark, Gunnel; Lövgren, Tanja; Rönnelid, Johan et al.

Ingår i Arthritis and Rheumatism, s. 1185-1195, 2005

• DOI för Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanism

Polymorphisms in the Tyrosine Kinase 2 and Interferon Regulatory Factor 5 Genes Are Associated with Systemic Lupus Erythematosus

Sigurdsson, Snaevar; Nordmark, Gunnel; Göring, Harald; Lindroos, Katarina et al.

Ingår i American Journal of Human Genetics, s. 528-537, 2005

• DOI för Polymorphisms in the Tyrosine Kinase 2 and Interferon Regulatory Factor 5 Genes Are Associated with Systemic Lupus Erythematosus

Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage

Gruic, Mirjana; Braga, Tiago; Lukinius, Agneta; Eloranta, Maija-Leena et al.

Ingår i Journal of Biological Chemistry, s. 33411-33418, 2005

• DOI för Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage

Induction of interferon-α production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG

Lövgren, Tanja; Eloranta, Maija-Leena; Båve, Ullvi; Alm, Gunnar V. et al.

Ingår i Arthritis and Rheumatism, s. 1861-1872, 2004

• DOI för Induction of interferon-α production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG

Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG

Båve, Ullvi; Magnuson, Mattias; Eloranta, Maija-Leena; Perers, Anders et al.

Ingår i Journal of Immunology, s. 3296-302, 2003

Effects of coxsackievirus B3 infection on the acute-phase protein metallothionein and on cytochrome P-4501A1 involved in the detoxification processes of TCDD in the mouse

Funseth, Eva; Påhlman, Martin; Eloranta, Maija-Leena; Friman, Gunnar et al.

Ingår i Science of the Total Environment, s. 37-47, 2002

• DOI för Effects of coxsackievirus B3 infection on the acute-phase protein metallothionein and on cytochrome P-4501A1 involved in the detoxification processes of TCDD in the mouse

Presence of cutaneous interferon-alpha producing cells in patients with systemic lupus erythematosus

Blomberg, Stina; Eloranta, Maija-Leena; Cederblad, Brita; Nordlin, K et al.

Ingår i Lupus, s. 484-90, 2001

• DOI för Presence of cutaneous interferon-alpha producing cells in patients with systemic lupus erythematosus

Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

Burska, Agata; Rodriguez-Carrio, Javier; Biesen, Robert; Dik, Willem A. et al.

Ingår i RMD Open, 2023

• DOI för Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
• Ladda ner fulltext (pdf) av Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

Rodriguez-Carrio, Javier; Burska, Agata; Conaghan, P. G.; Dik, Willem A. et al.

Ingår i RMD Open, 2023

• DOI för Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
• Ladda ner fulltext (pdf) av Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

The interferon signature in autoimmune diseases

Rönnblom, Lars; Eloranta, Maija-Leena

Ingår i Current Opinion in Rheumatology, s. 248-253, 2013

• DOI för The interferon signature in autoimmune diseases

Primary Sjögren's syndrome and the type I interferon system

Nordmark, Gunnel; Eloranta, Maija-Leena; Rönnblom, Lars

Ingår i Current Pharmaceutical Biotechnology, s. 2054-2062, 2012

The type I interferon system in the development of lupus

Rönnblom, Lars; Alm, Gunnar V; Eloranta, Maija-Leena

Ingår i Seminars in Immunology, s. 113-121, 2011

• DOI för The type I interferon system in the development of lupus

Type I interferon and lupus

Rönnblom, Lars; Alm, Gunnar V.; Eloranta, Maija-Leena

Ingår i Current Opinion in Rheumatology, s. 471-477, 2009

• DOI för Type I interferon and lupus

Endogenous type I interferon inducers in autoimmune diseases

Finke, Doreen; Eloranta, Maija-Leena; Rönnblom, Lars

Ingår i Autoimmunity, s. 349-352, 2009

• DOI för Endogenous type I interferon inducers in autoimmune diseases

The interferons. Further targeted therapies in rheumatology

Rönnblom, Lars; Eloranta, Maija-Leena; Alm, Gunnar

Ingår i Informa Healthcare, 2007

Type I Interferon signature in Nova Scotia duck tolling retriever dogs with steroid responsive meningitis-arteritis

Ahlgren, Kerstin; Wilbe, Maria; Sundberg, Katarina; Eloranta, Maija-Leena et al.

Activated T cells enhance interferon-alpha production by plasmacytoid dendritic cells stimulated by RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Dissection of genes in the type I interferon pathway reveals two novel risk loci for SLE

Sandling, Johanna K; Garnier, Sophie; Sigurdsson, Snaevar; Wang, Chuan et al.