Maija-Leena Eloranta
Forskare vid Institutionen för medicinska vetenskaper; Reumatologi
- Telefon:
- 018-471 45 42
- Mobiltelefon:
- 070-396 51 73
- E-post:
- Maija-Leena.Eloranta@medsci.uu.se
- Besöksadress:
- Rudbecklaboratoriet C11
751 85 Uppsala - Postadress:
- Rudbecklaboratoriet, C11
751 85 Uppsala
- Akademiska meriter:
- Docent
Publikationer
Senaste publikationer
Ingår i RMD Open, 2023
- DOI för Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
- Ladda ner fulltext (pdf) av Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
Ingår i RMD Open, 2023
- DOI för Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
- Ladda ner fulltext (pdf) av Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
Ingår i Lupus Science and Medicine, 2023
- DOI för B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
- Ladda ner fulltext (pdf) av B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
Ingår i Annals of the Rheumatic Diseases, s. 754-762, 2023
Ingår i Arthritis & Rheumatology, s. 1440-1450, 2022
- DOI för Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
- Ladda ner fulltext (pdf) av Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
Alla publikationer
Artiklar i tidskrift
Ingår i Lupus Science and Medicine, 2023
- DOI för B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
- Ladda ner fulltext (pdf) av B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
Ingår i Annals of the Rheumatic Diseases, s. 754-762, 2023
Ingår i Arthritis & Rheumatology, s. 1440-1450, 2022
- DOI för Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
- Ladda ner fulltext (pdf) av Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease
Ingår i Lupus Science and Medicine, 2022
- DOI för Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease
- Ladda ner fulltext (pdf) av Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease
Ingår i Nature Communications, 2022
- DOI för Genome-wide association study identifies Sjogren's risk loci with functional implications in immune and glandular cells
- Ladda ner fulltext (pdf) av Genome-wide association study identifies Sjogren's risk loci with functional implications in immune and glandular cells
Ingår i Arthritis & Rheumatology, s. 1842-1850, 2022
- DOI för Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome
- Ladda ner fulltext (pdf) av Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome
Different chest HRCT scan protocols change the extent of ground glass opacities
Ingår i BMC Pulmonary Medicine, 2022
- DOI för Different chest HRCT scan protocols change the extent of ground glass opacities
- Ladda ner fulltext (pdf) av Different chest HRCT scan protocols change the extent of ground glass opacities
Contributions of de novo variants to systemic lupus erythematosus
Ingår i European Journal of Human Genetics, s. 184-193, 2021
- DOI för Contributions of de novo variants to systemic lupus erythematosus
- Ladda ner fulltext (pdf) av Contributions of de novo variants to systemic lupus erythematosus
DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome
Ingår i Frontiers in Immunology, 2021
- DOI för DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome
- Ladda ner fulltext (pdf) av DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren's Syndrome
Ingår i Frontiers in Immunology, 2021
- DOI för C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205
- Ladda ner fulltext (pdf) av C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205
Ingår i Annals of the Rheumatic Diseases, s. 109-117, 2021
- DOI för Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
- Ladda ner fulltext (pdf) av Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
Ingår i Frontiers in Immunology, 2021
- DOI för Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus
- Ladda ner fulltext (pdf) av Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus
Ingår i Rheumatology, s. 3461-3470, 2021
- DOI för Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
- Ladda ner fulltext (pdf) av Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
Ingår i Annals of the Rheumatic Diseases, s. 363-369, 2020
- DOI för High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
- Ladda ner fulltext (pdf) av High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
Ingår i RMD Open, 2020
- DOI för Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
- Ladda ner fulltext (pdf) av Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
Ingår i Arthritis Research & Therapy, 2020
- DOI för The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells
- Ladda ner fulltext (pdf) av The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells
Ingår i Scandinavian Journal of Immunology, 2020
- DOI för Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists
- Ladda ner fulltext (pdf) av Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists
Ingår i PLOS Genetics, 2020
- DOI för Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling
- Ladda ner fulltext (pdf) av Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling
Ingår i Human Genetics, s. 141-150, 2019
- DOI för Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
- Ladda ner fulltext (pdf) av Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
Ingår i Rheumatology, s. 918-919, 2019
Ingår i Annals of the Rheumatic Diseases, s. 1363-1370, 2019
- DOI för Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
- Ladda ner fulltext (pdf) av Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
Ingår i European Journal of Human Genetics, s. 432-441, 2019
- DOI för A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
- Ladda ner fulltext (pdf) av A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
Ingår i Annals of the Rheumatic Diseases, s. 736-743, 2018
- DOI för DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
- Ladda ner fulltext (pdf) av DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
Ingår i Scandinavian Journal of Immunology, 2018
- DOI för Transcription profiling of peripheral B cells in antibody-positive primary Sjogren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature
- Ladda ner fulltext (pdf) av Transcription profiling of peripheral B cells in antibody-positive primary Sjogren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature
T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus
Ingår i Journal of Autoimmunity, s. 28-38, 2018
- DOI för T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus
- Ladda ner fulltext (pdf) av T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus
Interleukin-22 and associated genes are targets of microRNAs dysregulated
Ingår i Clinical and Experimental Rheumatology, 2018
Ingår i Annals of the Rheumatic Diseases, s. 1063-1069, 2018
- DOI för Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
- Ladda ner fulltext (pdf) av Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
Ingår i Annals of the Rheumatic Diseases, s. 1070-1077, 2018
- DOI för The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE
- Ladda ner fulltext (pdf) av The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE
Ingår i Arthritis Research & Therapy, 2018
- DOI för Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor
- Ladda ner fulltext (pdf) av Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor
Ingår i Human Gene Therapy, 2018
ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
Ingår i Scientific Reports, 2018
- DOI för ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
- Ladda ner fulltext (pdf) av ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
Ingår i Clinical and Experimental Immunology, s. 83-91, 2017
Novel risk genes for systemic lupus erythematosus predicted by random forest classification
Ingår i Scientific Reports, 2017
- DOI för Novel risk genes for systemic lupus erythematosus predicted by random forest classification
- Ladda ner fulltext (pdf) av Novel risk genes for systemic lupus erythematosus predicted by random forest classification
Type I IFN System Activation In Newborns Exposed To ANTI-RO/SSA Autoantibodies In Utero
Ingår i Annals of the Rheumatic Diseases, s. 182-182, 2017
High Genetic Risk Score Is Associated with Increased Organ Damage in SLE
Ingår i Arthritis & Rheumatology, 2017
Type I IFN System Activation In Newborns Exposed To Anti-Ro/Ssa Autoantibodies In Utero
Ingår i Annals of the Rheumatic Diseases, 2017
Treatment-Associated DNA Methylation Patterns in Systemic Lupus Erythematosus
Ingår i Arthritis & Rheumatology, 2017
Ingår i Arthritis & Rheumatology, 2017
Ingår i PLOS Genetics, 2017
- DOI för Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons
- Ladda ner fulltext (pdf) av Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons
Ingår i PLOS ONE, 2017
- DOI för Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype
- Ladda ner fulltext (pdf) av Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype
Activated Plasmacytoid Dendritic Cells (PDCS) Alter The Composition of The Blood B Cell Subsets
Ingår i Annals of the Rheumatic Diseases, s. 179-179, 2016
Ingår i Annals of the Rheumatic Diseases, s. 277-277, 2016
Ingår i Annals of the Rheumatic Diseases, s. 2029-2036, 2016
- DOI för Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes
- Ladda ner fulltext (pdf) av Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes
Cause and consequences of the activated type I interferon system in SLE
Ingår i Journal of Molecular Medicine, s. 1103-1110, 2016
- DOI för Cause and consequences of the activated type I interferon system in SLE
- Ladda ner fulltext (pdf) av Cause and consequences of the activated type I interferon system in SLE
Ingår i Arthritis & Rheumatology, s. 1045-1045, 2016
Ingår i Annals of the Rheumatic Diseases, s. 1728-1734, 2016
Ingår i Molecular Medicine, s. 322-328, 2016
- DOI för Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.
- Ladda ner fulltext (pdf) av Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.
Ingår i Human Genetics, s. 485-497, 2016
- DOI för Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression
- Ladda ner fulltext (pdf) av Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression
Genome-Wide Analysis of DNA Methylation Profiles in Multiple Tissues in Primary Sjogren's Syndrome
Ingår i Scandinavian Journal of Immunology, s. 412-412, 2015
Genome-wide analysis of DNA methylation in systemic lupus erythematosus
Ingår i Clinical and Experimental Rheumatology, 2015
Ingår i Human Molecular Genetics, s. 3571-3581, 2015
Identification of Novel Sjogren's Syndrome Risk Loci in the Regions of TNFAIP3 and PRDM1
Ingår i Arthritis & Rheumatology, 2015
Ingår i ARTHRITIS & RHEUMATOLOGY, s. 1000-1011, 2015
Ingår i Arthritis & Rheumatology, 2015
Ingår i Arthritis & Rheumatology, 2014
Genome-Wide DNA Methylation Analysis of CD19+B Cells in Primary Sjogren's Syndrome
Ingår i Arthritis & Rheumatology, 2014
High-Throughput Sequencing of 219 Candidate Genes for Identification of SLE-Associated Risk Variants
Ingår i Arthritis & Rheumatology, 2014
Ingår i Scandinavian Journal of Rheumatology, s. 88-89, 2014
Ingår i Scandinavian Journal of Rheumatology, s. 92-92, 2014
An NFKB1 gene promoter polymorphism is associated with primary Sjogren's syndrome
Ingår i Scandinavian Journal of Rheumatology, s. 87-88, 2014
Ingår i Arthritis & rheumatology, s. 1568-1573, 2014
Ingår i Arthritis and Rheumatism, s. 2424-2429, 2013
NCR3/NKp30 Contributes to Pathogenesis in Primary Sjögren's Syndrome
Ingår i Science Translational Medicine, 2013
Anti-NKG2A autoantibodies in a patient with systemic lupus erythematosus
Ingår i Rheumatology, s. 1818-1823, 2013
Ingår i Arthritis and Rheumatism, s. 2216, 2013
RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE
Ingår i PLOS ONE, s. 54487, 2013
- DOI för RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE
- Ladda ner fulltext (pdf) av RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE
Two rare disease-associated tyk2 variants are catalytically impaired but signaling competent
Ingår i Journal of Immunology, s. 2335-2344, 2013
Ingår i Arthritis and Rheumatism, s. 853-863, 2013
Ingår i Nature Genetics, s. 1284-1292, 2013
Association of genes in the NF-κB pathway with antibody positive primary Sjögren's syndrome
Ingår i Scandinavian Journal of Immunology, s. 447-454, 2013
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
Ingår i Genome Biology, 2013
Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
Ingår i Genes and Immunity, s. 217-222, 2013
- DOI för Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
- Ladda ner fulltext (pdf) av Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations
Ingår i European Journal of Human Genetics, s. 994-999, 2013
Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis
Ingår i PLOS ONE, 2013
- DOI för Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis
- Ladda ner fulltext (pdf) av Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis
Ingår i Annals of the Rheumatic Diseases, s. 96-103, 2013
Ingår i Journal of Immunology, s. 2989-2998, 2013
Ingår i Circulation, s. 255-263, 2013
The NKp30/B7H6 Axis Contributes To Pathogenesis In Primary Sjogren's Syndrome.
Ingår i Arthritis and Rheumatism, 2013
On the Origin of the Type I Interferon Activity in Rheumatoid Arthritis
Ingår i Annals of the Rheumatic Diseases, 2013
Ingår i Annals of the Rheumatic Diseases, s. 270-270, 2013
Ingår i Lupus, s. 586-595, 2012
SLE immune complexes upregulate the expression of slamf7 (cd319) on plasmacytoid dendritic cells
Ingår i Annals of the Rheumatic Diseases, 2012
Ingår i Arthritis and Rheumatism, s. 788-798, 2012
B lymphocytes enhance the interferon-α production by plasmacytoid dendritic cells
Ingår i Arthritis and Rheumatism, s. 3409-3419, 2012
On the Origin of the Type I Interferon Signature in Rheumatoid Arthritis
Ingår i Arthritis and Rheumatism, 2012
Ingår i Arthritis and Rheumatism, 2012
Ingår i Arthritis and Rheumatism, 2012
Ingår i Arthritis and Rheumatism, 2012
Ingår i Journal of Immunology, s. 5085-5094, 2011
Ingår i Arthritis Research & Therapy, 2011
- DOI för Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus
- Ladda ner fulltext (pdf) av Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus
Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome
Ingår i Genes and Immunity, s. 100-109, 2011
Ingår i European Journal of Human Genetics, s. 479-484, 2011
Ingår i Connective Tissue Research, s. 290-300, 2011
Ingår i Annals of the Rheumatic Diseases, s. 1396-1402, 2010
Ingår i Arthritis and Rheumatism, s. 562-573, 2010
Ingår i Arthritis and Rheumatism, s. 3755-3760, 2009
Ingår i Arthritis and Rheumatism, s. 3081-3090, 2009
Ingår i Research in Veterinary Science, s. 490-497, 2009
Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE
Ingår i European Journal of Immunology, s. 2925-2935, 2009
Ingår i Arthritis and Rheumatism, s. 2418-2427, 2009
Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome
Ingår i Genes and Immunity, s. 68-76, 2009
Ingår i Immunology, s. 140-6, 2009
Ingår i Journal of Experimental Medicine, s. 1661-1671, 2009
Ingår i Human Molecular Genetics, s. 872-881, 2008
Ingår i Human Molecular Genetics, s. 2868-2876, 2008
Ingår i Journal of Clinical Immunology, s. 220-31, 2008
Ingår i Arthritis and Rheumatism, s. 3112-3124, 2007
Interleukin-6 and tumour necrosis factor in synovial fluid from horses with carpal joint pathology
Ingår i Journal of Veterinary Medicine A, s. 346-351, 2007
Ingår i Arthritis and Rheumatism, s. 1917-1927, 2006
Ingår i Arthritis and Rheumatism, s. 1185-1195, 2005
Ingår i American Journal of Human Genetics, s. 528-537, 2005
Ingår i Journal of Biological Chemistry, s. 33411-33418, 2005
Ingår i Arthritis and Rheumatism, s. 1861-1872, 2004
Ingår i Journal of Immunology, s. 3296-302, 2003
Ingår i Science of the Total Environment, s. 37-47, 2002
Presence of cutaneous interferon-alpha producing cells in patients with systemic lupus erythematosus
Ingår i Lupus, s. 484-90, 2001
Artiklar, forskningsöversikt
Ingår i RMD Open, 2023
- DOI för Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
- Ladda ner fulltext (pdf) av Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
Ingår i RMD Open, 2023
- DOI för Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
- Ladda ner fulltext (pdf) av Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider
The interferon signature in autoimmune diseases
Ingår i Current Opinion in Rheumatology, s. 248-253, 2013
Primary Sjögren's syndrome and the type I interferon system
Ingår i Current Pharmaceutical Biotechnology, s. 2054-2062, 2012
The type I interferon system in the development of lupus
Ingår i Seminars in Immunology, s. 113-121, 2011
Ingår i Current Opinion in Rheumatology, s. 471-477, 2009
Endogenous type I interferon inducers in autoimmune diseases
Ingår i Autoimmunity, s. 349-352, 2009
Kapitel i böcker, delar av antologi
The interferons. Further targeted therapies in rheumatology
Ingår i Informa Healthcare, 2007