Staffan Svärd

Stuck on you Giardia

Svärd, Staffan

Ingår i Nature Microbiology, s. 1757-1758, 2026

• DOI för Stuck on you Giardia

First report of Hexamita nelsoni in blue mussel (Mytilus edulis): morphology, phylogeny, and host-parasite interaction

Alfjorden, Anders; Jerlström-Hultqvist, Jon; Svärd, Staffan; Burki, Fabien

Ingår i Journal of Invertebrate Pathology, 2026

• DOI för First report of Hexamita nelsoni in blue mussel (Mytilus edulis): morphology, phylogeny, and host-parasite interaction

Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet

Tichkule, Swapnil; Van Oosterhout, Cock; Caccio, Simone M.; Weisz, Filip et al.

Ingår i Nature Communications, 2025

• DOI för Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet
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The expanded genome of Hexamita inflata, a free-living diplomonad

Akdeniz, Zeynep; Havelka, Michal; Stoklasa, Michal; Jiménez-González, Alejandro et al.

Ingår i Scientific Data, 2025

• DOI för The expanded genome of Hexamita inflata, a free-living diplomonad
• Ladda ner fulltext (pdf) av The expanded genome of Hexamita inflata, a free-living diplomonad

Occurrence of intestinal parasites and bacteria, with the emphasis on Giardia intestinalis in children under 5 years old in Magude village, Maputo, Mozambique

Casmo, Veronica; Noormahomed, Emilia; Knörr, Livia; Lebbad, Marianne et al.

2024

Stuck on you Giardia

Svärd, Staffan

Ingår i Nature Microbiology, s. 1757-1758, 2026

• DOI för Stuck on you Giardia

First report of Hexamita nelsoni in blue mussel (Mytilus edulis): morphology, phylogeny, and host-parasite interaction

Alfjorden, Anders; Jerlström-Hultqvist, Jon; Svärd, Staffan; Burki, Fabien

Ingår i Journal of Invertebrate Pathology, 2026

• DOI för First report of Hexamita nelsoni in blue mussel (Mytilus edulis): morphology, phylogeny, and host-parasite interaction

Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet

Tichkule, Swapnil; Van Oosterhout, Cock; Caccio, Simone M.; Weisz, Filip et al.

Ingår i Nature Communications, 2025

• DOI för Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet
• Ladda ner fulltext (pdf) av Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet

The expanded genome of Hexamita inflata, a free-living diplomonad

Akdeniz, Zeynep; Havelka, Michal; Stoklasa, Michal; Jiménez-González, Alejandro et al.

Ingår i Scientific Data, 2025

• DOI för The expanded genome of Hexamita inflata, a free-living diplomonad
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Tetramerization of deoxyadenosine kinase meets the demands of a DNA replication substrate challenge in Giardia intestinalis

Ranjbarian, Farahnaz; Rafie, Karim; Shankar, Kasturika; Krakovka, Sascha et al.

Ingår i Nucleic Acids Research, s. 14061-14076, 2024

• DOI för Tetramerization of deoxyadenosine kinase meets the demands of a DNA replication substrate challenge in Giardia intestinalis
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Gene co-expression network analysis reveal core responsive genes in Parascaris univalens tissues following ivermectin exposure

Dube, Faruk; Delhomme, Nicolas; Martin, Frida; Hinas, Andrea et al.

Ingår i PLOS ONE, 2024

• DOI för Gene co-expression network analysis reveal core responsive genes in Parascaris univalens tissues following ivermectin exposure
• Ladda ner fulltext (pdf) av Gene co-expression network analysis reveal core responsive genes in Parascaris univalens tissues following ivermectin exposure

Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis

Majumdar, Soneya; Emmerich, Andrew G; Krakovka, Sascha; Mandava, Chandra Sekhar et al.

Ingår i Nucleic Acids Research, s. 3436-3451, 2023

• DOI för Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
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Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain

Dube, Faruk; Hinas, Andrea; Delhomme, Nicolas; Åbrink, Magnus et al.

Ingår i PLOS ONE, 2023

• DOI för Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain
• Ladda ner fulltext (pdf) av Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain

Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis

Motyckova, Alzbeta; Voleman, Lubos; Najdrova, Vladimira; Arbonova, Lenka et al.

Ingår i PLoS Pathogens, 2023

• DOI för Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis
• Ladda ner fulltext (pdf) av Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis

Transcriptomic analysis of albendazole resistance in human diarrheal parasite Giardia duodenalis

Su, Qiao; Baker, Louise; Emery, Samantha; Balan, Balu et al.

Ingår i International Journal for Parasitology, s. 9-19, 2023

• DOI för Transcriptomic analysis of albendazole resistance in human diarrheal parasite Giardia duodenalis
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Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection

Grüttner, Jana; van Rijn, Jorik M.; Geiser, Petra; Florbrant, Alexandra et al.

Ingår i PLoS Pathogens, 2023

• DOI för Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection
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Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro

Dube, Faruk; Hinas, Andrea; Roy, Shweta; Martin, Frida et al.

Ingår i Parasites & Vectors, 2022

• DOI för Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro
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A chromosome-scale reference genome for Spironucleus salmonicida

Xu, Feifei; Jimenez-Gonzalez, Alejandro; Kurt, Zeynep; Ástvaldsson, Ásgeir et al.

Ingår i Scientific Data, 2022

• DOI för A chromosome-scale reference genome for Spironucleus salmonicida
• Ladda ner fulltext (pdf) av A chromosome-scale reference genome for Spironucleus salmonicida

Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery

Krakovka, Sascha; Ranjbarian, Farahnaz; Lujan, Lucas A.; Saura, Alicia et al.

Ingår i Journal of Biological Chemistry, 2022

• DOI för Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery
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Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics

Krakovka, Sascha; Ribacke, Ulf; Miyamoto, Yukiko; Eckmann, Lars et al.

Ingår i Frontiers in Microbiology, 2022

• DOI för Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics
• Ladda ner fulltext (pdf) av Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics

Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Metamonada

Santos, Rui; Astvaldsson, Asgeir; Pipaliya, Shweta; Zumthor, Jon Paulin et al.

Ingår i BMC Biology, 2022

• DOI för Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Metamonada
• Ladda ner fulltext (pdf) av Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Metamonada

High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium

van Rijn, Jorik M.; Eriksson, Jens; Grüttner, Jana; Sundbom, Magnus et al.

Ingår i mBio, 2022

• DOI för High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium
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Comprehensive characterization of Cysteine-rich protein-coding genes of Giardia lamblia and their role during antigenic variation

Rodriguez-Walker, Macarena; Molina, Cecilia R.; Lujan, Lucas A.; Saura, Alicia et al.

Ingår i Genomics, 2022

• DOI för Comprehensive characterization of Cysteine-rich protein-coding genes of Giardia lamblia and their role during antigenic variation
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Giardia duodenalis

Rojas-Lopez, Laura; Marques, Rafael C.; Svärd, Staffan

Ingår i Trends in Parasitology, s. 605-606, 2022

• DOI för Giardia duodenalis
• Ladda ner fulltext (pdf) av Giardia duodenalis

A Detailed Gene Expression Map of Giardia Encystation

Rojas-Lopez, Laura; Krakovka, Sascha; Einarsson, Elin; Ribacke, Ulf et al.

Ingår i Genes, s. 1932, 2021

• DOI för A Detailed Gene Expression Map of Giardia Encystation
• Ladda ner fulltext (pdf) av A Detailed Gene Expression Map of Giardia Encystation

Serglycin-Deficiency Causes Reduced Weight Gain and Changed Intestinal Cytokine Responses in Mice Infected With Giardia intestinalis

Li, Zhiqiang; Peirasmaki, Dimitra; Svärd, Staffan; Åbrink, Magnus

Ingår i Frontiers in Immunology, 2021

• DOI för Serglycin-Deficiency Causes Reduced Weight Gain and Changed Intestinal Cytokine Responses in Mice Infected With Giardia intestinalis
• Ladda ner fulltext (pdf) av Serglycin-Deficiency Causes Reduced Weight Gain and Changed Intestinal Cytokine Responses in Mice Infected With Giardia intestinalis

Dual RNA-seq transcriptome analysis of caecal tissue during primary Eimeria tenella infection in chickens

Sandholt, Arnar K. S.; Wattrang, Eva; Lilja, Tobias; Ahola, Harri et al.

Ingår i BMC Genomics, 2021

• DOI för Dual RNA-seq transcriptome analysis of caecal tissue during primary Eimeria tenella infection in chickens
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Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics

Balan, Balu; Emery-Corbin, Samantha J.; Sandow, Jarrod J.; Ansell, Brendan Robert E. et al.

Ingår i International Journal of Parasitology, s. 809-824, 2021

• DOI för Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics
• Ladda ner fulltext (pdf) av Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics

Eukaryote-conserved histone post-translational modification landscape in Giardia duodenalis revealed by mass spectrometry

Emery-Corbin, Samantha J.; Hamey, Joshua J.; Balan, Balu; Rojas-López, Laura et al.

Ingår i International Journal of Parasitology, s. 225-239, 2021

• DOI för Eukaryote-conserved histone post-translational modification landscape in Giardia duodenalis revealed by mass spectrometry

Dual RNA-Seq transcriptome analysis of chicken macrophage-like cells (HD11) infected in vitro with Eimeria tenella

Sandholt, Arnar K. S.; Xu, Feifei; Söderlund, Robert; Lundén, Anna et al.

Ingår i Parasitology, s. 712-725, 2021

• DOI för Dual RNA-Seq transcriptome analysis of chicken macrophage-like cells (HD11) infected in vitro with Eimeria tenella
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Eukaryote-Conserved Methylarginine Is Absent in Diplomonads and Functionally Compensated in Giardia

Emery-Corbin, Samantha J.; Hamey, Joshua J.; Ansell, Brendan R. E.; Balan, Balu et al.

Ingår i Molecular biology and evolution, s. 3525-3549, 2020

• DOI för Eukaryote-Conserved Methylarginine Is Absent in Diplomonads and Functionally Compensated in Giardia
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High Cysteine Membrane Proteins (HCMPs) Are Up-Regulated DuringGiardia-Host Cell Interactions

Peirasmaki, Dimitra; Ma'ayeh, Showgy Y.; Xu, Feifei; Ferella, Marcela et al.

Ingår i Frontiers in Genetics, 2020

• DOI för High Cysteine Membrane Proteins (HCMPs) Are Up-Regulated DuringGiardia-Host Cell Interactions
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The Chymase Mouse Mast Cell Protease-4 Regulates Intestinal Cytokine Expression in Mature Adult Mice Infected with Giardia intestinalis

Li, Zhiqiang; Peirasmaki, Dimitra; Svärd, Staffan; Åbrink, Magnus

Ingår i Cells, 2020

• DOI för The Chymase Mouse Mast Cell Protease-4 Regulates Intestinal Cytokine Expression in Mature Adult Mice Infected with Giardia intestinalis
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The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites

Xu, Feifei; Jimenez-Gonzalez, Alejandro; Einarsson, Elin; Ástvaldsson, Ásgeir et al.

Ingår i Microbial Genomics, 2020

• DOI för The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites

A chromosome-scale reference genome for Giardia intestinalis WB

Xu, Feifei; Jex, Aaron; Svärd, Staffan

Ingår i Scientific Data, 2020

• DOI för A chromosome-scale reference genome for Giardia intestinalis WB
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Giardia intestinalis cystatin is a potent inhibitor of papain, parasite cysteine proteases and, to a lesser extent, human cathepsin B

Liu, Jingyi; Svärd, Staffan; Klotz, Christian

Ingår i FEBS Letters, s. 1313-1325, 2019

• DOI för Giardia intestinalis cystatin is a potent inhibitor of papain, parasite cysteine proteases and, to a lesser extent, human cathepsin B

Oxygen induces the expression of invasion and stress response genes in the anaerobic salmon parasite Spironucleus salmonicida

Stairs, Courtney W.; Kokla, Anna; Astvaldsson, Asgeir; Jerlström-Hultqvist, Jon et al.

Ingår i BMC Biology, 2019

• DOI för Oxygen induces the expression of invasion and stress response genes in the anaerobic salmon parasite Spironucleus salmonicida
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Further evaluation of recombinant Tsol-p27 by enzyme-linked immunoelectrotransfer blot for the serodiagnosis of cysticercosis in pigs from Mozambique

Nhancupe, Noemia; Noormahomed, Emilia V.; Afonso, Sonia; Svärd, Staffan et al.

Ingår i Parasites & Vectors, 2019

• DOI för Further evaluation of recombinant Tsol-p27 by enzyme-linked immunoelectrotransfer blot for the serodiagnosis of cysticercosis in pigs from Mozambique
• Ladda ner fulltext (pdf) av Further evaluation of recombinant Tsol-p27 by enzyme-linked immunoelectrotransfer blot for the serodiagnosis of cysticercosis in pigs from Mozambique

Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia

Davids, Barbara J.; Liu, Ching M.; Hanson, Elaine M.; Le, Christine H. Y. et al.

Ingår i Infection and Immunity, 2019

• DOI för Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia

Proximity Staining using Enzymatic Protein Tagging in Diplomonads

Astvaldsson, Asgeir; Hultenby, Kjell; Svärd, Staffan; Jerlstrom-Hultqvist, Joel

Ingår i mSphere, 2019

• DOI för Proximity Staining using Enzymatic Protein Tagging in Diplomonads
• Ladda ner fulltext (pdf) av Proximity Staining using Enzymatic Protein Tagging in Diplomonads

Giardia excretory-secretory proteins modulate the enzymatic activities of mast cell chymase and tryptase

Li, Zhiqiang; Peirasmaki, Dimitra; Svärd, Staffan; Åbrink, Magnus

Ingår i Molecular Immunology, s. 535-544, 2019

• DOI för Giardia excretory-secretory proteins modulate the enzymatic activities of mast cell chymase and tryptase

Cleavage specificity of recombinant Giardia intestinalis cysteine proteases: Degradation of immunoglobulins and defensins

Liu, Jingyi; Fu, Zhirong; Hellman, Lars; Svärd, Staffan G.

Ingår i Molecular and biochemical parasitology (Print), s. 29-38, 2019

• DOI för Cleavage specificity of recombinant Giardia intestinalis cysteine proteases: Degradation of immunoglobulins and defensins

Proteomic diversity in a prevalent human-infective Giardia duodenalis sub-species

Emery-Corbin, Samantha J.; Vuong, Daniel; Lacey, Ernest; Svärd, Staffan et al.

Ingår i International Journal of Parasitology, s. 817-823, 2018

• DOI för Proteomic diversity in a prevalent human-infective Giardia duodenalis sub-species

A novel high-resolution multilocus sequence typing of Giardia intestinalis Assemblage A isolates reveals zoonotic transmission, clonal outbreaks and recombination

Ankarklev, Johan; Lebbad, Marianne; Einarsson, Elin; Franzen, Oscar et al.

Ingår i Infection, Genetics and Evolution, s. 7-16, 2018

• DOI för A novel high-resolution multilocus sequence typing of Giardia intestinalis Assemblage A isolates reveals zoonotic transmission, clonal outbreaks and recombination

Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis

Emery, Samantha J.; Baker, Louise; Ansell, Brendan R. E.; Mirzaei, Mehdi et al.

Ingår i GigaScience, 2018

• DOI för Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis
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Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

Liu, Jingyi; Ma'ayeh, Showgy Y.; Peirasmaki, Dimitra; Lundstrom-Stadelmann, Britta et al.

Ingår i Virulence, s. 879-894, 2018

• DOI för Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines
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Responses of the Differentiated Intestinal Epithelial Cell Line Caco-2 to Infection With the Giardia intestinalis GS Isolate

Ma'ayeh, Showgy Y.; Knörr, Livia; Sköld, Karin; Garnham, Alexandra et al.

Ingår i Frontiers in Cellular and Infection Microbiology, 2018

• DOI för Responses of the Differentiated Intestinal Epithelial Cell Line Caco-2 to Infection With the Giardia intestinalis GS Isolate
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Recent advances in the genomic and molecular biology of Giardia

Guadalupe Ortega-Pierres, M.; Jex, Aaron R.; Ansell, Brendan R. E.; Svärd, Staffan

Ingår i Acta Tropica, s. 67-72, 2018

• DOI för Recent advances in the genomic and molecular biology of Giardia

Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines

Ansell, Brendan R. E.; Baker, Louise; Emery, Samantha J.; McConville, Malcolm J. et al.

Ingår i Frontiers in Microbiology, 2017

• DOI för Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines
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Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum

Voleman, Lubos; Najdrova, Vladimira; Ástvaldsson, Ásgeir; Tumova, Pavla et al.

Ingår i BMC Biology, 2017

• DOI för Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum
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Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome

Hanevik, Kurt; Kristoffersen, Einar; Morch, Kristine; Rye, Kristin Paulsen et al.

Ingår i BMC Immunology, 2017

• DOI för Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome
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Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells

Ma'ayeh, Showgy Y.; Liu, Jingyi; Peirasmaki, Dimitra; Hörnaeus, Katarina et al.

Ingår i PLoS Neglected Tropical Diseases, 2017

• DOI för Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells
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Endoplasmic reticulum is the sorting core facility in the Golgi-lacking protozoan Giardia lamblia

Zamponi, Nahuel; Zamponi, Emiliano; Mayol, Gonzalo F.; Lanfredi-Rangel, Adriana et al.

Ingår i Traffic, s. 604-621, 2017

• DOI för Endoplasmic reticulum is the sorting core facility in the Golgi-lacking protozoan Giardia lamblia

On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp PC1

Xu, Feifei; Jerlström-Hultqvist, Jon; Kolisko, Martin; Simpson, Alastair G. B. et al.

Ingår i BMC Biology, 2016

• DOI för On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp PC1
• Ladda ner fulltext (pdf) av On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp PC1

Comparative cell biology and evolution of Annexins in Diplomonads

Einarsson, Elin; Ástvaldsson, Ásgeir; Hultenby, Kjell; Andersson, Jan O. et al.

Ingår i mSphere, 2016

• DOI för Comparative cell biology and evolution of Annexins in Diplomonads

Divergent Transcriptional Responses to Physiological and Xenobiotic Stress in Giardia duodenalis

Ansell, Brendan R. E.; McConville, Malcolm J.; Baker, Louise; Korhonen, Pasi K. et al.

Ingår i Antimicrobial Agents and Chemotherapy, s. 6034-6045, 2016

• DOI för Divergent Transcriptional Responses to Physiological and Xenobiotic Stress in Giardia duodenalis

Coordinated Changes in Gene Expression Throughout Encystation of Giardia intestinalis

Einarsson, Elin; Troell, Karin; Höppner, Marc; Grabherr, Mannfred et al.

Ingår i PLoS Neglected Tropical Diseases, 2016

• DOI för Coordinated Changes in Gene Expression Throughout Encystation of Giardia intestinalis
• Ladda ner fulltext (pdf) av Coordinated Changes in Gene Expression Throughout Encystation of Giardia intestinalis

Specific histone modifications play critical roles in the control of encystation and antigenic variation in the early-branching eukaryote Giardia lamblia

Carranza, Pedro G.; Gargantini, Pablo R.; Prucca, Cesar G.; Torri, Alessandro et al.

Ingår i International Journal of Biochemistry and Cell Biology, s. 32-43, 2016

• DOI för Specific histone modifications play critical roles in the control of encystation and antigenic variation in the early-branching eukaryote Giardia lamblia

Human Memory CD4+ T Cell Immune Responses against Giardia lamblia

Saghaug, Christina Skar; Sornes, Steinar; Peirasmaki, Dimitra; Svärd, Staffan et al.

Ingår i Clinical and Vaccine Immunology, s. 11-18, 2016

• DOI för Human Memory CD4+ T Cell Immune Responses against Giardia lamblia

Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates

Ankarklev, Johan; Franzen, Oscar; Peirasmaki, Dimitra; Jerlstrom-Hultqvist, Jon et al.

Ingår i BMC Genomics, 2015

• DOI för Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates
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UV irradiation responses in Giardia intestinalis

Einarsson, Elin; Svärd, Staffan G.; Troell, Karin

Ingår i Experimental parasitology, s. 25-32, 2015

• DOI för UV irradiation responses in Giardia intestinalis

A real-time assemblage-specific PCR assay for the detection of Giardia duodenalis assemblages A, B and E in fecal samples

Van Lith, Lindy; Soba, Barbara; Vizcaino, Vivian Villalba; Svärd, Staffan et al.

Ingår i Veterinary parasitology, s. 28-34, 2015

• DOI för A real-time assemblage-specific PCR assay for the detection of Giardia duodenalis assemblages A, B and E in fecal samples

Transcriptional profiling of Giardia intestinalis in response to oxidative stress

Ma'ayeh, Showgy Y.; Knörr, Livia; Svärd, Staffan G.

Ingår i International Journal of Parasitology, s. 925-938, 2015

• DOI för Transcriptional profiling of Giardia intestinalis in response to oxidative stress

Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites

Ansell, Brendan R. E.; McConville, Malcolm J.; Baker, Louise; Korhonen, Pasi K. et al.

Ingår i PLoS Neglected Tropical Diseases, 2015

• DOI för Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites
• Ladda ner fulltext (pdf) av Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites

The genome of Spironucleus salmonicida highlights a fish pathogen adapted to fluctuating environments

Xu, Feifei; Jerlström-Hultqvist, Jon; Einarsson, Elin; Astvaldsson, Asgeir et al.

Ingår i PLOS Genetics, 2014

• DOI för The genome of Spironucleus salmonicida highlights a fish pathogen adapted to fluctuating environments
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Rolf Bernander (1956-2014): pioneer of the archaeal cell cycle Obituary

Ettema, Thijs J. G.; Lindås, Ann-Christin; Hjort, Karin; Poplawski, Andrzej B. et al.

Ingår i Molecular Microbiology, s. 903-909, 2014

• DOI för Rolf Bernander (1956-2014): pioneer of the archaeal cell cycle Obituary

Gene expression changes during Giardia-host cell interactions in serum-free medium

Ferella, Marcela; Davids, Barbara J; Cipriano, Michael J; Birkeland, Shanda R et al.

Ingår i Molecular and biochemical parasitology (Print), s. 21-23, 2014

• DOI för Gene expression changes during Giardia-host cell interactions in serum-free medium

The role of arginine and arginine-metabolizing enzymes during Giardia - host cell interactions in vitro

Stadelmann, Britta; Hanevik, Kurt; Andersson, Mattias K.; Bruserud, Oystein et al.

Ingår i BMC Microbiology, s. 256, 2013

• DOI för The role of arginine and arginine-metabolizing enzymes during Giardia - host cell interactions in vitro

Transcriptome Profiling of Giardia intestinalis Using Strand-specific RNAseq

Franzén, Oscar; Jerlström-Hultqvist, Jon; Einarsson, Elin; Ankarklev, Johan et al.

Ingår i PloS Computational Biology, 2013

• DOI för Transcriptome Profiling of Giardia intestinalis Using Strand-specific RNAseq
• Ladda ner fulltext (pdf) av Transcriptome Profiling of Giardia intestinalis Using Strand-specific RNAseq

Hydrogenosomes in the diplomonad Spironucleus salmonicida

Jerlström-Hultqvist, Jon; Einarsson, Elin; Xu, Feifei; Hjort, Karin et al.

Ingår i Nature Communications, s. 2493, 2013

• DOI för Hydrogenosomes in the diplomonad Spironucleus salmonicida

Common Coinfections of Giardia intestinalis and Helicobacter pylori in Non-Symptomatic Ugandan Children

Ankarklev, Johan; Hestvik, Elin; Lebbad, Marianne; Lindh, Johan et al.

Ingår i PLOS Neglected Tropical Diseases, 2012

• DOI för Common Coinfections of Giardia intestinalis and Helicobacter pylori in Non-Symptomatic Ugandan Children
• Ladda ner fulltext (pdf) av Common Coinfections of Giardia intestinalis and Helicobacter pylori in Non-Symptomatic Ugandan Children

Allelic sequence heterozygosity in single Giardia parasites

Ankarklev, Johan; Svärd, Staffan; Lebbad, Marianne

Ingår i BMC Microbiology, 2012

• DOI för Allelic sequence heterozygosity in single Giardia parasites

Plasmid Vectors for Proteomic Analyses in Giardia: Purification of Virulence Factors and Analysis of the Proteasome

Jerlström-Hultqvist, Jon; Stadelmann, Britta; Birkestedt, Sandra; Hellman, Ulf et al.

Ingår i Eukaryotic Cell, s. 864-873, 2012

• DOI för Plasmid Vectors for Proteomic Analyses in Giardia: Purification of Virulence Factors and Analysis of the Proteasome

Arginine Consumption by the Intestinal Parasite Giardia intestinalis Reduces Proliferation of Intestinal Epithelial Cells

Stadelmann, Britta; Merino, Maria C.; Persson, Lo; Svärd, Staffan G.

Ingår i PLOS ONE, 2012

• DOI för Arginine Consumption by the Intestinal Parasite Giardia intestinalis Reduces Proliferation of Intestinal Epithelial Cells
• Ladda ner fulltext (pdf) av Arginine Consumption by the Intestinal Parasite Giardia intestinalis Reduces Proliferation of Intestinal Epithelial Cells

Laboratory cryo soft X-ray microscopy

Hertz, H. M.; von Hofsten, O.; Bertilson, M.; Vogt, U. et al.

Ingår i Journal of Structural Biology, s. 267-272, 2012

• DOI för Laboratory cryo soft X-ray microscopy

Alpha-1 Giardin is an Annexin with Highly Unusual Calcium-Regulated Mechanisms

Weeratunga, Saroja K.; Osman, Asiah; Hu, Nien-Jen; Wang, Conan K. et al.

Ingår i Journal of Molecular Biology, s. 169-181, 2012

• DOI för Alpha-1 Giardin is an Annexin with Highly Unusual Calcium-Regulated Mechanisms

Stable transfection of the diplomonad parasite Spironucleus salmonicida

Jerlström-Hultqvist, Jon; Einarsson, Elin; Svärd, Staffan G

Ingår i Eukaryotic Cell, s. 1353-1361, 2012

• DOI för Stable transfection of the diplomonad parasite Spironucleus salmonicida

Detection of Giardia duodenalis Assemblages A and B in Human Feces by Simple, Assemblage-Specific PCR Assays

Vanni, Ilaria; Caccio, Simone Mario; van Lith, Lindy; Lebbad, Marianne et al.

Ingår i PLOS Neglected Tropical Diseases, 2012

• DOI för Detection of Giardia duodenalis Assemblages A and B in Human Feces by Simple, Assemblage-Specific PCR Assays
• Ladda ner fulltext (pdf) av Detection of Giardia duodenalis Assemblages A and B in Human Feces by Simple, Assemblage-Specific PCR Assays

Transcriptional changes in Giardia during host-parasite interactions

Ringqvist, Emma; Avesson, Lotta; Söderbom, Fredrik; Svärd, Staffan

Ingår i International Journal for Parasitology, s. 277-285, 2011

• DOI för Transcriptional changes in Giardia during host-parasite interactions

Multilocus Genotyping of Human Giardia Isolates Suggests Limited Zoonotic Transmission and Association between Assemblage B and Flatulence in Children

Lebbad, Marianne; Petersson, Ingvor; Karlsson, Lillemor; Botero-Kleiven, Silvia et al.

Ingår i PLoS Neglected Tropical Diseases, 2011

• DOI för Multilocus Genotyping of Human Giardia Isolates Suggests Limited Zoonotic Transmission and Association between Assemblage B and Flatulence in Children

Elongation factor 1-alpha is released into the culture medium during growth of Giardia intestinalis trophozoites

Skarin, Hanna; Ringqvist, Emma; Hellman, Ulf; Svärd, Staffan G.

Ingår i Experimental parasitology, s. 804-810, 2011

• DOI för Elongation factor 1-alpha is released into the culture medium during growth of Giardia intestinalis trophozoites

Real-time polymerase chain reaction followed by fast sequencing allows rapid genotyping of microbial pathogens

Wahab, Tara; Ankarklev, Johan; Lebbad, Marianne; Glavas, Steve et al.

Ingår i Scandinavian Journal of Infectious Diseases, s. 95-99, 2011

• DOI för Real-time polymerase chain reaction followed by fast sequencing allows rapid genotyping of microbial pathogens

The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

Manning, Gerard; Reiner, David S.; Lauwaet, Tineke; Dacre, Michael et al.

Ingår i Genome Biology, 2011

• DOI för The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
• Ladda ner fulltext (pdf) av The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

Human Cellular Immune Response Against Giardia lamblia 5 Years After Acute Giardiasis

Hanevik, Kurt; Kristoffersen, Einar; Svärd, Staffan; Bruserud, Oystein et al.

Ingår i Journal of Infectious Diseases, s. 1779-1786, 2011

• DOI för Human Cellular Immune Response Against Giardia lamblia 5 Years After Acute Giardiasis

alpha 1-giardin based live heterologous vaccine protects against Giardia lamblia infection in a murine model

Jenikova, Gabriela; Hruz, Petr; Andersson, Mattias K.; Tejman-Yarden, Noa et al.

Ingår i Vaccine, s. 9529-9537, 2011

• DOI för alpha 1-giardin based live heterologous vaccine protects against Giardia lamblia infection in a murine model

Large genomic differences between the morphologically indistinguishable diplomonads Spironucleus barkhanus and Spironucleus salmonicida

Roxström-Lindquist, Katarina; Jerlström-Hultqvist, Jon; Jörgensen, Anders; Troell, Karin et al.

Ingår i BMC Genomics, 2010

• DOI för Large genomic differences between the morphologically indistinguishable diplomonads Spironucleus barkhanus and Spironucleus salmonicida
• Ladda ner fulltext (pdf) av Large genomic differences between the morphologically indistinguishable diplomonads Spironucleus barkhanus and Spironucleus salmonicida

Comment on article by Eligio-Garcia et al. entitled "Frequency of Giardia intestinalis assemblages isolated from dogs and humans in a community from Culiacan, Sinaloa, Mexico using beta-giardin restriction gene"

Lebbad, Marianne; Svärd, Staffan

Ingår i Veterinary parasitology, s. 159-160, 2008

• DOI för Comment on article by Eligio-Garcia et al. entitled "Frequency of Giardia intestinalis assemblages isolated from dogs and humans in a community from Culiacan, Sinaloa, Mexico using beta-giardin restriction gene"

Dominance of Giardia assemblage B in León, Nicaragua.

Lebbad, Marianne; Ankarklev, Johan; Tellez, Aleyda; Leiva, Byron et al.

Ingår i Acta Tropica, s. 44-53, 2008

• DOI för Dominance of Giardia assemblage B in León, Nicaragua.

Eukaryotic RNase P RNA mediates cleavage in the absence of protein

Kikovska, Ema; Svärd, Staffan; Kirsebom, Leif

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 2062-2067, 2007

• DOI för Eukaryotic RNase P RNA mediates cleavage in the absence of protein

Protein phosphatase 2A plays a crucial role in Giardia lamblia differentiation

Lauwaet, Tineke; Davids, Barbara J.; Torres-Escobar, Ascención; Birkeland, Shanda R. et al.

Ingår i Molecular and biochemical parasitology (Print), s. 80-89, 2007

• DOI för Protein phosphatase 2A plays a crucial role in Giardia lamblia differentiation

Developmental changes in the adhesive disk during Giardia differentiation.

Palm, Daniel; Weiland, Malin; McArthur, Andrew G; Winiecka-Krusnell, Jadwiga et al.

Ingår i Mol Biochem Parasitol, s. 199-207, 2005

Secretory antibodies against Giardia intestinalis in lactating Nicaraguan women.

Tellez, A; Palm, D; Weiland, M; Alemán, J et al.

Ingår i Parasite Immunol, s. 163-9, 2005

Giardia lamblia-induced changes in gene expression in differentiated Caco-2

Roxström-Lindquist, Katarina; Ringqvist, Emma; Palm, Daniel; Svärd, Staffan

Ingår i Infect Immun, s. 8204-8, 2005

Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference

Buret, Andre G.; Caccio, Simone M.; Favennec, Loic; Svärd, Staffan

Ingår i Parasite, 2020

• DOI för Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference
• Ladda ner fulltext (pdf) av Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference

Host specificity in the Giardia duodenalis species complex

Caccio, Simone M.; Lalle, Marco; Svärd, Staffan

Ingår i Infection, Genetics and Evolution, s. 335-345, 2018

• DOI för Host specificity in the Giardia duodenalis species complex

An up-date on Giardia and giardiasis

Einarsson, Elin; Ma'ayeh, Showgy Y.; Svärd, Staffan G.

Ingår i Current Opinion in Microbiology, s. 47-52, 2016

• DOI för An up-date on Giardia and giardiasis

Drug resistance in Giardia duodenalis

Ansell, Brendan R. E.; McConville, Malcolm J.; Ma'ayeh, Showgy Y.; Dagley, Michael J. et al.

Ingår i Biotechnology Advances, s. 888-901, 2015

• DOI för Drug resistance in Giardia duodenalis

Behind the smile: cell biology and disease mechanisms of Giardia species

Ankarklev, Johan; Jerlström-Hultqvist, Jon; Ringqvist, Emma; Troell, Karin et al.

Ingår i Nature Reviews Microbiology, s. 413-422, 2010

• DOI för Behind the smile: cell biology and disease mechanisms of Giardia species

A genomic survey of the fish parasite Spironucleus salmonicida indicates genomic plasticity among diplomonads and significant lateral gene transfer in eukaryote genome evolution

Andersson, Jan O.; Sjögren, Åsa M.; Horner, David S.; Murphy, Colleen A. et al.

Ingår i BMC Genomics, s. 51, 2007

• DOI för A genomic survey of the fish parasite Spironucleus salmonicida indicates genomic plasticity among diplomonads and significant lateral gene transfer in eukaryote genome evolution

Giardia and giardiasis

Ma'ayeh, Showgy Y.; Svärd, Staffan

Ingår i Molecular Medical Microbiology, s. 3107-3119, Elsevier, 2023

• DOI för Giardia and giardiasis

Transcriptomic and proteomic analyses of Giardia intestinalis: Intestinal epithelial cell interactions

Emery-Corbin, Samantha J.; Grüttner, Jana; Svärd, Staffan

Ingår i Giardia And Giardiasis, Pt B, s. 139-171, Elsevier, 2020

• DOI för Transcriptomic and proteomic analyses of Giardia intestinalis: Intestinal epithelial cell interactions

Recent advances in functional research in Giardia intestinalis

Jex, Aaron R.; Svärd, Staffan; Hagen, Kari D.; Starcevich, Hannah et al.

Ingår i Giardia And Giardiasis, Pt B, s. 97-137, Elsevier, 2020

• DOI för Recent advances in functional research in Giardia intestinalis

The genome of Giardia and other diplomonads

Andersson, Jan O.; Jerlström-Hultqvist, Jon; Svärd, Staffan G.

Ingår i Anaerobic Parasitic Protozoa: Genomics and Molecular Biology, s. 23-44, Caister Academic Press, 2010

Occurrence of intestinal parasites and bacteria, with the emphasis on Giardia intestinalis in children under 5 years old in Magude village, Maputo, Mozambique

Casmo, Veronica; Noormahomed, Emilia; Knörr, Livia; Lebbad, Marianne et al.

2024

Experimental challenge of Atlantic salmon (Salmo salar) with the diplomonad parasite Spironucleus salmonicida to characterize the infection cycle

Anders, Alfjorden; Astvaldsson, Asgeir; Eva, Jansson; Svärd, Staffan

High Cysteine Proteins are up-regulated during Giardia-host cell interaction.

Peirasmaki, Dimitra; Ma'ayeh, Showgy Y.; Xu, Feifei; Ferella, Marcela et al.

Proteome analyses of Giardia–host cell interactions in vitro.

Peirasmaki, Dimitra; Xia, Dong; Attree, Elizabeth; Ferella, Marcela et al.

Proteomic profiling of host cell responses during Giardia intestinalis interaction with intestinal epithelial Caco-2 cells

Grüttner, Jana; Svärd, Staffan

Dual transcriptomic analysis of Spironucleus salmonicida-infected salmon cells identifies putative virulence factors and host responses

Astvaldsson, Asgeir; Stairs, Courtney W.; Xu, Feifei; Haag, Lars et al.