Publikationer

Anti-gene oligonucleotides targeting Friedreich's ataxia expanded GAA•TTC repeats increase Frataxin expression

Mozafari, Negin; Milagres, Salome; Umek, Tea; Rocha, Cristina S. J. et al.

Ingår i Molecular Therapy Nucleic Acids, 2025

• DOI för Anti-gene oligonucleotides targeting Friedreich's ataxia expanded GAA•TTC repeats increase Frataxin expression
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On the road to blood biomarkers in myasthenia gravis (MG): Beyond clinical scales

Bhandage, Amol; Huang, Yu-Fang; Punga, Tanel; Rostedt Punga, Anna

Ingår i Journal of Neuromuscular Diseases, 2025

• DOI för On the road to blood biomarkers in myasthenia gravis (MG): Beyond clinical scales

Δ133p53α and Δ160p53α isoforms of the tumor suppressor protein p53 exert dominant-negative effect primarily by co-aggregation

Zhao, Liuqun; Punga, Tanel; Sanyal, Suparna

Ingår i eLIFE, 2025

• DOI för Δ133p53α and Δ160p53α isoforms of the tumor suppressor protein p53 exert dominant-negative effect primarily by co-aggregation
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Complex regulation of mitochondrial signaling by human adenovirus minor capsid protein VI

Schubert, Erik; Mun, Kwangchol; Larsson, Mårten; Panagiotou, Styliani et al.

Ingår i Journal of Virology, 2024

• DOI för Complex regulation of mitochondrial signaling by human adenovirus minor capsid protein VI

Serum protein biomarker profile distinguishes acetylcholine receptor antibody seropositive myasthenia gravis patients from healthy controls.

Bhandage, Amol; Kenina, Viktorija; Huang, Yu-Fang; Roddate, Marija et al.

Ingår i iScience, s. 110564, 2024

• DOI för Serum protein biomarker profile distinguishes acetylcholine receptor antibody seropositive myasthenia gravis patients from healthy controls.
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Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism

Hajikhezri, Zamaneh; Kaira, Yanina; Schubert, Erik; Darweesh, Mahmoud et al.

Ingår i Journal of Virology, 2023

• DOI för Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism

The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts

Kases, Katharina; Schubert, Erik; Hajikhezri, Zamaneh; Larsson, Mårten et al.

Ingår i Journal of Biological Chemistry, 2023

• DOI för The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
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Activation of the Ca²⁺/NFAT pathway by assembly of hepatitis C virus core protein into nucleocapsid-like particles

Devi, Priya; Punga, Tanel; Bergqvist, Anders

Ingår i Viruses, 2022

• DOI för Activation of the Ca²⁺/NFAT pathway by assembly of hepatitis C virus core protein into nucleocapsid-like particles
• Ladda ner fulltext (pdf) av Activation of the Ca²⁺/NFAT pathway by assembly of hepatitis C virus core protein into nucleocapsid-like particles

Next-Generation Sequencing Analysis of CpG Methylation of a Tumor Suppressor Gene SHP-1 Promoter in Stable Cell Lines and HCV-Positive Patients

Devi, Priya; Engdahl, Katarina; Punga, Tanel; Bergqvist, Anders

Ingår i Viruses, 2022

• DOI för Next-Generation Sequencing Analysis of CpG Methylation of a Tumor Suppressor Gene SHP-1 Promoter in Stable Cell Lines and HCV-Positive Patients
• Ladda ner fulltext (pdf) av Next-Generation Sequencing Analysis of CpG Methylation of a Tumor Suppressor Gene SHP-1 Promoter in Stable Cell Lines and HCV-Positive Patients

Structural Insights into Human Adenovirus Type 4 Virus-Associated RNA I

Bergquist, Helen; Inturi, Raviteja; Zain, Rula; Punga, Tanel

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Structural Insights into Human Adenovirus Type 4 Virus-Associated RNA I
• Ladda ner fulltext (pdf) av Structural Insights into Human Adenovirus Type 4 Virus-Associated RNA I

ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression

Darweesh, Mahmoud; Younis, Shady; Hajikhezri, Zamaneh; Ali, Arwa et al.

Ingår i Frontiers in Immunology, 2022

• DOI för ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
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Hepatitis C Virus Core Protein Down-Regulates Expression of Src-Homology 2 Domain Containing Protein Tyrosine Phosphatase by Modulating Promoter DNA Methylation

Devi, Priya; Ota, Seisuke; Punga, Tanel; Bergqvist, Anders

Ingår i Viruses, s. 2514-2514, 2021

• DOI för Hepatitis C Virus Core Protein Down-Regulates Expression of Src-Homology 2 Domain Containing Protein Tyrosine Phosphatase by Modulating Promoter DNA Methylation
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Adenovirus in the omics era - a multi-pronged strategy.

Zhao, Hongxing; Punga, Tanel; Pettersson, Ulf

Ingår i FEBS Letters, s. 1879-1890, 2020

• DOI för Adenovirus in the omics era - a multi-pronged strategy.

Circulating miRNAs as Potential Biomarkers in Myasthenia Gravis: Tools for Personalized Medicine

Sabre, Liis; Punga, Tanel; Rostedt Punga, Anna

Ingår i Frontiers in Immunology, 2020

• DOI för Circulating miRNAs as Potential Biomarkers in Myasthenia Gravis: Tools for Personalized Medicine
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Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs

Fiorillo, Alyson A.; Heier, Christopher R.; Huang, Yu-Fang; Tully, Christopher B. et al.

Ingår i Frontiers in Immunology, 2020

• DOI för Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs
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miR-1933-3p is upregulated in skeletal muscles of MuSK+ EAMG mice and affects Impa1 and Mrpl27

Bogatikov, Evgenii; Lindblad, Ida; Punga, Tanel; Rostedt Punga, Anna

Ingår i Neuroscience research, s. 46-52, 2020

• DOI för miR-1933-3p is upregulated in skeletal muscles of MuSK+ EAMG mice and affects Impa1 and Mrpl27

Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections

Hajikhezri, Zamaneh; Darweesh, Mahmoud; Akusjärvi, Göran; Punga, Tanel

Ingår i Viruses, 2020

• DOI för Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections
• Ladda ner fulltext (pdf) av Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections

Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs

Punga, Tanel; Darweesh, Mahmoud; Akusjärvi, Göran

Ingår i Viruses, 2020

• DOI för Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs
• Ladda ner fulltext (pdf) av Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs

Cellular Zinc Finger Protein 622 Hinders Human Adenovirus Lytic Growth and Limits Binding of the Viral pVII Protein to Virus DNA

Mun, Kwangchol; Punga, Tanel

Ingår i Journal of Virology, 2019

• DOI för Cellular Zinc Finger Protein 622 Hinders Human Adenovirus Lytic Growth and Limits Binding of the Viral pVII Protein to Virus DNA

Circulating microRNAs as potential biomarkers in myasthenia gravis patients.

Rostedt Punga, Anna; Punga, Tanel

Ingår i Annals of the New York Academy of Sciences, s. 33-40, 2018

• DOI för Circulating microRNAs as potential biomarkers in myasthenia gravis patients.

Human Adenovirus Infection Causes Cellular E3 Ubiquitin Ligase MKRN1 Degradation Involving the Viral Core Protein pVII.

Inturi, Raviteja; Mun, Kwangchol; Singethan, Katrin; Schreiner, Sabrina et al.

Ingår i Journal of Virology, 2018

• DOI för Human Adenovirus Infection Causes Cellular E3 Ubiquitin Ligase MKRN1 Degradation Involving the Viral Core Protein pVII.

In Situ Detection of Adenovirus DNA and mRNA in Individual Cells.

Punga, Tanel; Ciftci, Sibel; Nilsson, Mats; Krzywkowski, Tomasz

Ingår i Current protocols in microbiology, 2018

• DOI för In Situ Detection of Adenovirus DNA and mRNA in Individual Cells.

Thymectomy lowers the myasthenia gravis biomarker miR-150-5p

Molin, Carl Johan; Sabre, Liis; Weis, Cleo-Aron; Punga, Tanel et al.

Ingår i Neurology, 2018

• DOI för Thymectomy lowers the myasthenia gravis biomarker miR-150-5p
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Expression profile of Epstein-Barr virus and human adenovirus small RNAs in tonsillar B and T lymphocytes

Assadian, Farzaneh; Kamel, Wael; Laurell, Göran; Svensson, Catharina et al.

Ingår i PLOS ONE, 2017

• DOI för Expression profile of Epstein-Barr virus and human adenovirus small RNAs in tonsillar B and T lymphocytes
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Simultaneous Single-Cell In Situ Analysis of Human Adenovirus Type 5 DNA and mRNA Expression Patterns in Lytic and Persistent Infection

Krzywkowski, Tomasz; Ciftci, Sibel; Assadian, Farzaneh; Nilsson, Mats et al.

Ingår i Journal of Virology, 2017

• DOI för Simultaneous Single-Cell In Situ Analysis of Human Adenovirus Type 5 DNA and mRNA Expression Patterns in Lytic and Persistent Infection

The adenovirus L4-22K protein regulates transcription and RNA splicing via a sequence-specific single-stranded RNA binding

Lan, Susan; Kamel, Wael; Punga, Tanel; Akusjärvi, Göran

Ingår i Nucleic Acids Research, s. 1731-1742, 2017

• DOI för The adenovirus L4-22K protein regulates transcription and RNA splicing via a sequence-specific single-stranded RNA binding
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Clamping of RNA with PNA enables targeting of microRNA

Ghidini, Alice; Bergquist, Helen; Murtola, Merita; Punga, Tanel et al.

Ingår i Organic and biomolecular chemistry, s. 5210-5213, 2016

• DOI för Clamping of RNA with PNA enables targeting of microRNA

Disease specific enrichment of circulating let-7 family microRNA in MuSK+ myasthenia gravis.

Punga, Tanel; Bartoccioni, Emanuela; Lewandowska, Marta; Damato, Valentina et al.

Ingår i Journal of Neuroimmunology, s. 21-26, 2016

• DOI för Disease specific enrichment of circulating let-7 family microRNA in MuSK+ myasthenia gravis.
• Ladda ner fulltext (pdf) av Disease specific enrichment of circulating let-7 family microRNA in MuSK+ myasthenia gravis.

Distribution and Molecular Characterization of Human Adenovirus and Epstein-Barr Virus Infections in Tonsillar Lymphocytes Isolated from Patients Diagnosed with Tonsillar Diseases

Assadian, Farzaneh; Sandström, Karl; Bondeson, Kåre; Laurell, Göran et al.

Ingår i PLOS ONE, 2016

• DOI för Distribution and Molecular Characterization of Human Adenovirus and Epstein-Barr Virus Infections in Tonsillar Lymphocytes Isolated from Patients Diagnosed with Tonsillar Diseases
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A suppressive effect of Sp1 recruitment to the first leader 5' splice site region on L4-22K-mediated activation of the adenovirus major late promoter

Lan, Susan; Östberg, Sara; Punga, Tanel; Akusjärvi, Göran

Ingår i Virus Research, s. 133-140, 2015

• DOI för A suppressive effect of Sp1 recruitment to the first leader 5' splice site region on L4-22K-mediated activation of the adenovirus major late promoter

Complementation of the human adenovirus type 5 VA RNAI defect by the Vaccinia virus E3L protein and serotype-specific VA RNAIs

Inturi, Raviteja; Kamel, Wael; Akusjärvi, Göran; Punga, Tanel

Ingår i Virology, s. 25-35, 2015

• DOI för Complementation of the human adenovirus type 5 VA RNAI defect by the Vaccinia virus E3L protein and serotype-specific VA RNAIs

Disease specific signature of circulating miR-150-5p and miR-21-5p in myasthenia gravis patients

Punga, Anna Rostedt; Andersson, Mats; Alimohammadi, Mohammad; Punga, Tanel

Ingår i Journal of the Neurological Sciences, s. 90-96, 2015

• DOI för Disease specific signature of circulating miR-150-5p and miR-21-5p in myasthenia gravis patients
• Ladda ner fulltext (pdf) av Disease specific signature of circulating miR-150-5p and miR-21-5p in myasthenia gravis patients

Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils

Assadian, Farzaneh; Sandström, Karl; Laurell, Göran; Svensson, Catharina et al.

Ingår i Journal of Visualized Experiments, 2015

• DOI för Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils

Genome-Engineering Tools to Establish Accurate Reporter Cell Lines That Enable Identification of Therapeutic Strategies to Treat Friedreich's Ataxia

Villaseñor, Rodrigo; Miraglia, Loren; Romero, Angelica; Tu, Buu et al.

Ingår i Journal of Biomolecular Screening, s. 760-767, 2015

• DOI för Genome-Engineering Tools to Establish Accurate Reporter Cell Lines That Enable Identification of Therapeutic Strategies to Treat Friedreich's Ataxia

Opposite expression of CYP51A1 and its natural antisense transcript AluCYP51A1 in adenovirus type 37 infected retinal pigmented epithelial cells

Pickl, Julia Maria Anna; Kamel, Wael; Ciftci, Sibel; Punga, Tanel et al.

Ingår i FEBS Letters, s. 1383-1388, 2015

• DOI för Opposite expression of CYP51A1 and its natural antisense transcript AluCYP51A1 in adenovirus type 37 infected retinal pigmented epithelial cells

A splice variant of the human phosphohistidine phosphatase 1 (PHPT1) is degraded by the proteasome

Inturi, Raviteja; Wäneskog, Marcus; Vlachakis, Dimitrios; Ali, Yeasmeen et al.

Ingår i International Journal of Biochemistry and Cell Biology, s. 69-75, 2014

• DOI för A splice variant of the human phosphohistidine phosphatase 1 (PHPT1) is degraded by the proteasome
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Circulating miRNAs in myasthenia gravis: miR-150-5p as a new potential biomarker

Punga, Tanel; Le Panse, Rozen; Andersson, Mats; Truffault, Frédérique et al.

Ingår i Annals of clinical and translational neurology, s. 49-58, 2014

• DOI för Circulating miRNAs in myasthenia gravis: miR-150-5p as a new potential biomarker

Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance

Kamel, Wael; Segerman, Bo; Punga, Tanel; Akusjärvi, Göran

Ingår i PLOS ONE, 2014

• DOI för Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance
• Ladda ner fulltext (pdf) av Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance

Adenovirus Precursor pVII Protein Stability Is Regulated By Its Propeptide Sequence

Inturi, Raviteja; Thaduri, Srinivas; Punga, Tanel

Ingår i PLOS ONE, 2013

• DOI för Adenovirus Precursor pVII Protein Stability Is Regulated By Its Propeptide Sequence
• Ladda ner fulltext (pdf) av Adenovirus Precursor pVII Protein Stability Is Regulated By Its Propeptide Sequence

Muscle-specific regulation of the mTOR signaling pathway in MuSK antibody seropositive (MuSK plus ) experimental autoimmune Myasthenia gravis (EAMG)

Chauhan, Mayank; Punga, Tanel; Punga, Anna Rostedt

Ingår i Neuroscience research, s. 102-109, 2013

• DOI för Muscle-specific regulation of the mTOR signaling pathway in MuSK antibody seropositive (MuSK plus ) experimental autoimmune Myasthenia gravis (EAMG)

Old and new functions for the adenovirus virus-associated RNAs

Punga, Tanel; Kamel, Wael; Akusjarvi, Göran

Ingår i Future Virology, s. 343-356, 2013

• DOI för Old and new functions for the adenovirus virus-associated RNAs

The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells

Kamel, Wael; Segerman, Bo; Oberg, Daniel; Punga, Tanel et al.

Ingår i Nucleic Acids Research, s. 4802-4812, 2013

• DOI för The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells
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Two Cellular Protein Kinases, DNA-PK and PKA, Phosphorylate the Adenoviral L4-33K Protein and Have Opposite Effects on L1 Alternative RNA Splicing

Törmänen Persson, Heidi; Aksaas, Anne Kristin; Kvissel, Anne Katrine; Punga, Tanel et al.

Ingår i PLOS ONE, 2012

• DOI för Two Cellular Protein Kinases, DNA-PK and PKA, Phosphorylate the Adenoviral L4-33K Protein and Have Opposite Effects on L1 Alternative RNA Splicing
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Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe

Woolcock, Katrina J; Gaidatzis, Dimos; Punga, Tanel; Bühler, Marc

Ingår i Nature Structural & Molecular Biology, s. 94-99, 2011

• DOI för Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe

Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation

Punga, Tanel; Bühler, Marc

Ingår i EMBO Molecular Medicine, s. 120-129, 2010

• DOI för Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation

Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection

Motallebipour, Mehdi; Enroth, Stefan; Punga, Tanel; Ameur, Adam et al.

Ingår i The FEBS Journal, s. 1878-1890, 2009

• DOI för Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection

Hyperphosphorylation regulates the activity of SREBP1 during mitosis

Bengoechea-Alonso, Maria T; Punga, Tanel; Ericsson, Johan

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 11681-11686, 2005

• DOI för Hyperphosphorylation regulates the activity of SREBP1 during mitosis

YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress

Grönroos, Eva; Terentiev, Alexei A; Punga, Tanel; Ericsson, Johan

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 12165-12170, 2004

• DOI för YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress

Adenovirus 2 E1B-55K protein relieves p53-mediated transcriptional repression of the survivin and MAP4 promoters

Punga, Tanel; Akusjärvi, Göran

Ingår i FEBS Letters, s. 214-218, 2003

• DOI för Adenovirus 2 E1B-55K protein relieves p53-mediated transcriptional repression of the survivin and MAP4 promoters

Functional inactivation of the SR family of splicing factors during a vaccinia virus infection

Huang, Tien-Sheng; Estmer Nilsson, Camilla; Punga, Tanel; Akusjärvi, Göran

Ingår i EMBO Reports, s. 1088-1093, 2002

• DOI för Functional inactivation of the SR family of splicing factors during a vaccinia virus infection