Publikationer

A novel HPV16 splicing enhancer critical for viral oncogene expression and cell immortalization. 

Jönsson, Johanna; Wang, Lianqing; Kajitani, Naoko; Schwartz, Stefan

Ingår i Nucleic Acids Research, 2024

• DOI för A novel HPV16 splicing enhancer critical for viral oncogene expression and cell immortalization. 
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RNA elements that control human papillomavirus mRNA splicing-targets for therapy?

Schwartz, Stefan; Wu, Chengjun; Kajitani, Naoko

Ingår i Journal of Medical Virology, 2024

• DOI för RNA elements that control human papillomavirus mRNA splicing-targets for therapy?
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HnRNP D activates production of HPV16 E1 and E6 mRNAs by promoting intron retention

Cui, Xiaoxu; Hao, Chengyu; Gong, Lijing; Kajitani, Naoko et al.

Ingår i Nucleic Acids Research, s. 2782-2806, 2022

• DOI för HnRNP D activates production of HPV16 E1 and E6 mRNAs by promoting intron retention
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hnRNP G/RBMX enhances HPV16 E2 mRNA splicing through a novel splicing enhancer and inhibits production of spliced E7 oncogene mRNAs

Hao, Chengyu; Zheng, Yunji; Jönsson, Johanna; Cui, Xiaoxu et al.

Ingår i Nucleic Acids Research, s. 3867-3891, 2022

• DOI för hnRNP G/RBMX enhances HPV16 E2 mRNA splicing through a novel splicing enhancer and inhibits production of spliced E7 oncogene mRNAs
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Identification of heterogenous nuclear ribonucleoproteins (hnRNPs) and serine- and arginine-rich (SR) proteins that induce human papillomavirus type 16 late gene expression and alter L1 mRNA splicing

Hao, Chengyu; Gong, Lijing; Cui, Xiaoxu; Jönsson, Johanna et al.

Ingår i Archives of Virology, s. 563-570, 2022

• DOI för Identification of heterogenous nuclear ribonucleoproteins (hnRNPs) and serine- and arginine-rich (SR) proteins that induce human papillomavirus type 16 late gene expression and alter L1 mRNA splicing
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Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing.

Cui, Xiaoxu; Nilsson, Kersti; Kajitani, Naoko; Schwartz, Stefan

Ingår i Virus genes, s. 98-112, 2022

• DOI för Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing.
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The role of RNA-binding proteins in the processing of mRNAs produced by carcinogenic papillomaviruses

Kajitani, Naoko; Schwartz, Stefan

Ingår i Seminars in Cancer Biology, s. 482-496, 2022

• DOI för The role of RNA-binding proteins in the processing of mRNAs produced by carcinogenic papillomaviruses
• Ladda ner fulltext (pdf) av The role of RNA-binding proteins in the processing of mRNAs produced by carcinogenic papillomaviruses

Inefficient splicing of segment 7 and 8 mRNAs is an inherent property of influenza virus A/Brevig Mission/1918/1 (H1N1) that causes elevated expression of NS1 protein

Backström Winquist, Ellenor; Abdurahman, Samir; Tranell, Anna; Lindström, Sofia et al.

Ingår i Virology, s. 46-58, 2012

• DOI för Inefficient splicing of segment 7 and 8 mRNAs is an inherent property of influenza virus A/Brevig Mission/1918/1 (H1N1) that causes elevated expression of NS1 protein

Inhibition of splicing by serine-arginine rich protein 55 (SRp55) causes the appearance of partially spliced HIV-1 mRNAs in the cytoplasm

Tranell, Anna; Tingsborg, Susanne; Fenyö, Eva Maria; Schwartz, Stefan

Ingår i Virus Research, s. 82-91, 2011

• DOI för Inhibition of splicing by serine-arginine rich protein 55 (SRp55) causes the appearance of partially spliced HIV-1 mRNAs in the cytoplasm

Serine/arginine-rich protein 30c activates human papillomavirus type 16 L1 mRNA expression via a bimodal mechanism

Somberg, Monika; Li, Xiaoze; Johansson, Cecilia; Orru, Beatrice et al.

Ingår i Journal of General Virology, s. 2411-2421, 2011

• DOI för Serine/arginine-rich protein 30c activates human papillomavirus type 16 L1 mRNA expression via a bimodal mechanism

Multiple ASF/SF2 Sites in the Human Papillomavirus Type 16 (HPV-16) E4-Coding Region Promote Splicing to the Most Commonly Used 3'-Splice Site on the HPV-16 Genome

Somberg, Monika; Schwartz, Stefan

Ingår i Journal of Virology, s. 8219-8230, 2010

• DOI för Multiple ASF/SF2 Sites in the Human Papillomavirus Type 16 (HPV-16) E4-Coding Region Promote Splicing to the Most Commonly Used 3'-Splice Site on the HPV-16 Genome

Serine- and Arginine-rich Proteins 55 and 75 (SRp55 and SRp75) Induce Production of HIV-1 vpr mRNA by Inhibiting the 5 '-Splice Site of Exon 3

Tranell, Anna; Fenyo, Eva Maria; Schwartz, Stefan

Ingår i Journal of Biological Chemistry, s. 31537-31547, 2010

• DOI för Serine- and Arginine-rich Proteins 55 and 75 (SRp55 and SRp75) Induce Production of HIV-1 vpr mRNA by Inhibiting the 5 '-Splice Site of Exon 3

Adenovirus E4orf4 induces HPV-16 late L1 mRNA production

Somberg, Monika; Rush, Margaret; Fay, Joanna; Ryan, Fergus et al.

Ingår i Virology, s. 279-290, 2009

• DOI för Adenovirus E4orf4 induces HPV-16 late L1 mRNA production

Increased expression of cellular RNA-binding proteins in HPV-induced neoplasia and cervical cancer

Fay, Joanna; Kelehan, Peter; Lambkin, Helen; Schwartz, Stefan

Ingår i Journal of Medical Virology, s. 897-907, 2009

• DOI för Increased expression of cellular RNA-binding proteins in HPV-induced neoplasia and cervical cancer

HPV-16 RNA processing

Schwartz, Stefan

Ingår i Frontiers in Bioscience, s. 5880-5891, 2008

• DOI för HPV-16 RNA processing

Inhibition of HPV-16 L1 expression from L1 cDNAs correlates with the presence of hnRNP A1 binding sites in the L1 coding region

Zhao, Xiaomin; Schwartz, Stefan

Ingår i Virus genes, s. 45-53, 2008

• DOI för Inhibition of HPV-16 L1 expression from L1 cDNAs correlates with the presence of hnRNP A1 binding sites in the L1 coding region

Polypyrimidine tract binding protein induces human papillomavirus type 16 late gene expression by interfering with splicing inhibitory elements at the major late 5' splice site, SD3632

Somberg, Monika; Zhao, Xiaomin; Fröhlich, Monika; Evander, Magnus et al.

Ingår i Journal of Virology, s. 3665-3678, 2008

• DOI för Polypyrimidine tract binding protein induces human papillomavirus type 16 late gene expression by interfering with splicing inhibitory elements at the major late 5' splice site, SD3632

Identification of a 17-nucleotide splicing enhancer in HPV-16 L1 that counteracts the effect of multiple hnRNP A1-binding splicing silencers

Zhao, Xiaomin; Fay, Joanna; Lambkin, Helen; Schwartz, Stefan

Ingår i Virology, s. 351-363, 2007

• DOI för Identification of a 17-nucleotide splicing enhancer in HPV-16 L1 that counteracts the effect of multiple hnRNP A1-binding splicing silencers

The presence of inhibitory RNA elements in the late 3'-untranslated region is a conserved property of human papillomaviruses

Zhao, Xiaomin; Rush, Margaret; Carlsson, Anette; Schwartz, Stefan

Ingår i Virus Research, s. 135-144, 2007

• DOI för The presence of inhibitory RNA elements in the late 3'-untranslated region is a conserved property of human papillomaviruses

A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein

Zhao, Xiaomin; Öberg, Daniel; Rush, Margaret; Fay, Joanna et al.

Ingår i Journal of Virology, s. 4270-4288, 2005

• DOI för A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein

A Downstream Polyadenylation Element in Human Papillomavirus Type 16 L2 Encodes Multiple GGG Motifs and Interacts with hnRNP H

Öberg, Daniel; Fay, Joanna; Lambkin, Helen; Schwartz, Stefan

Ingår i Journal of Virology, s. 9254-9269, 2005

• DOI för A Downstream Polyadenylation Element in Human Papillomavirus Type 16 L2 Encodes Multiple GGG Motifs and Interacts with hnRNP H

A splicing enhancer in the E4 coding region of human papillomavirus type 16 is required for early mRNA splicing and polyadenylation as well as inhibition of premature late gene expression.

Rush, Margaret; Zhao, Xiaomin; Schwartz, Stefan

Ingår i J Virol, s. 12002-15, 2005

HPV-16 L1 genes with inactivated negative RNA elements induce potent immune responses.

Rollman, Erik; Arnheim, Lisen; Collier, Brian; Oberg, Daniel et al.

Ingår i Virology, s. 182-9, 2004

Identification of an hnRNP A1-dependent splicing silencer in the human papillomavirus type 16 L1 coding region that prevents premature expression of the late L1 gene.

Zhao, Xiaomin; Rush, Margaret; Schwartz, Stefan

Ingår i J Virol, s. 10888-905, 2004