Reumatologi

Innate immune cell subsets are enriched in synovial fluid of ACPA-negative rheumatoid arthritis and characterized by distinct type I IFN gene signatures

Argyriou, Alexandra; Wadsworth, Marc H.; Fienman, Joshua; Gonzalez-Sanchez, Ana Cristina et al.

Ingår i Annals of the Rheumatic Diseases, s. 265-275, 2026

• DOI för Innate immune cell subsets are enriched in synovial fluid of ACPA-negative rheumatoid arthritis and characterized by distinct type I IFN gene signatures
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A proteomic profile correlates with salivary gland inflammation and disease-associated antibodies in Sjögren’s disease

Björk, Albin; Mofors, Johannes; Meneghel, Lauro; Kvarnström, Marika et al.

Ingår i Annals of the Rheumatic Diseases, s. 339-350, 2026

• DOI för A proteomic profile correlates with salivary gland inflammation and disease-associated antibodies in Sjögren’s disease
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Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus

Eloranta, Maija-Leena; Nygren, Peter; Larsson, Rolf; Loskog, Angelica et al.

Ingår i Scientific Reports, 2026

• DOI för Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus
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IL40: A Newly Described Cytokine With Conflicting Measurements and Detection Variability - Are There Different Forms?

Euler, Nora; Huang, Wenqi; Hemmingsson, Peter; Juto, Anna et al.

Ingår i Scandinavian Journal of Immunology, 2026

• DOI för IL40: A Newly Described Cytokine With Conflicting Measurements and Detection Variability - Are There Different Forms?
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Large-scale proteome profiling identifies circulating biomarkers for disease activity and organ involvement in ANCA-associated vasculitides

Hellbacher, Erik; Knight, Ann; Hemmingsson, Peter; Juto, Anna et al.

Ingår i Frontiers in Immunology, 2026

• DOI för Large-scale proteome profiling identifies circulating biomarkers for disease activity and organ involvement in ANCA-associated vasculitides
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Implementing Federated Analysis Using DataSHIELD in the DREAM TO TREAT Atopic Dermatitis Registries Collaboration

Krogh, Niels Steen; Prieto-Merino, David; Coker, Bolaji; Birkner, Thomas et al.

Ingår i Journal of Investigative Dermatology, 2026

• DOI för Implementing Federated Analysis Using DataSHIELD in the DREAM TO TREAT Atopic Dermatitis Registries Collaboration

Certolizumab pegol, abatacept, tocilizumab or active conventional therapy in early rheumatoid arthritis: 48-week patient-reported outcomes from the NORD-STAR trial

Lampa, Jon; Nordstrom, Dan; van Vollenhoven, Ronald; Hetland, Merete Lund et al.

Ingår i The Lancet Rheumatology, 2026

• DOI för Certolizumab pegol, abatacept, tocilizumab or active conventional therapy in early rheumatoid arthritis: 48-week patient-reported outcomes from the NORD-STAR trial

Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity

Lindelöf, Linnea; Garred, Peter; Hong, Mun-Gwan; Wahl Vaelum, Sasha et al.

Ingår i Lupus Science and Medicine, 2026

• DOI för Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity
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Genetic risk factors and clinical manifestations of systemic lupus erythematosus: Large‐scale analysis of genetic predisposition and disease subtypes

Reid, Sarah; Sandling, Johanna K.; Pucholt, Pascal; Sayadi, Ahmed et al.

Ingår i Journal of Internal Medicine, s. 95-108, 2026

• DOI för Genetic risk factors and clinical manifestations of systemic lupus erythematosus: Large‐scale analysis of genetic predisposition and disease subtypes
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Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment

Sayadi, Ahmed; Eloranta, Maija-Leena; Oparina, Nina Y.; Wallgren, Marcus et al.

Ingår i Journal of Autoimmunity, 2026

• DOI för Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment
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Genetic and epigenetic determinants of relapse risk in lupus nephritis

Skoglund, Elisabeth; Skoglund, Oliver; Vestin, Holme; Oparina, Nina et al.

Ingår i Lupus Science and Medicine, 2026

• DOI för Genetic and epigenetic determinants of relapse risk in lupus nephritis
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Comparison of BAFF and type I IFN activity in blood and placenta in SLE and healthy pregnancies

Torell, Agnes; Andersson, Kerstin; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Ingår i Lupus Science and Medicine, 2026

• DOI för Comparison of BAFF and type I IFN activity in blood and placenta in SLE and healthy pregnancies
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Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome

Vasaitis, Lilian; Blomstrand, Lena; Pandzic, Tatjana; Gulyas, Miklos et al.

Ingår i Rheumatology & Autoimmunity, s. 60-62, 2026

• DOI för Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome
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High-intensity interval training outperforms moderate exercise to improve aerobic capacity in patients with recent-onset idiopathic inflammatory myopathies: a multicentre randomised controlled trial

Andreasson, Kristofer M.; Leijding, Cecilia; Dastmalchi, Maryam; Notarnicola, Antonella et al.

Ingår i eBioMedicine, 2025

• DOI för High-intensity interval training outperforms moderate exercise to improve aerobic capacity in patients with recent-onset idiopathic inflammatory myopathies: a multicentre randomised controlled trial
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Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale

Badrising, U. A.; Henderson, R.; Reddel, S.; Corbett, A. et al.

Ingår i Clinical and Experimental Rheumatology, s. 316-325, 2025

• DOI för Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale

Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Bianchi, Matteo; Kozyrev, Sergey V.; Notarnicola, Antonella; Sandling, Johanna K. et al.

Ingår i Arthritis & Rheumatology, s. 212-225, 2025

• DOI för Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases
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Sex disparities in the phenotype at diagnosis of Sjögren's disease: artificial intelligence-driven characterisation in 17,416 patients

Brito-Zeron, P.; Flores-Chavez, A.; Horvath, I. F.; Priori, R. et al.

Ingår i Clinical and Experimental Rheumatology, s. 2133-2141, 2025

• DOI för Sex disparities in the phenotype at diagnosis of Sjögren's disease: artificial intelligence-driven characterisation in 17,416 patients

Rheumatoid Arthritis Related B-Cell Changes Are Found Already in the Risk-RA Phase

de Vries, Charlotte; Huang, Wenqi; Sharma, Ravi Kumar; Wangriatisak, Kittikorn et al.

Ingår i European Journal of Immunology, 2025

• DOI för Rheumatoid Arthritis Related B-Cell Changes Are Found Already in the Risk-RA Phase
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Immunological signatures in patients with Sjögren's disease: association with systemic disease activity at diagnosis

Delgado, L.; Flores-Chavez, A.; Szanto, A.; Priori, R. et al.

Ingår i Clinical and Experimental Rheumatology, s. 2124-2132, 2025

• DOI för Immunological signatures in patients with Sjögren's disease: association with systemic disease activity at diagnosis

HLA-B27 has wide clinical impact on juvenile idiopathic arthritis - Eighteen years of follow-up in the population-based Nordic Juvenile Idiopathic Arthritis Cohort

Ekelund, Maria; Szentpetery, Agnes; Arnstad, Ellen D; Aalto, Kristina et al.

Ingår i ACR Open Rheumatology, 2025

• DOI för HLA-B27 has wide clinical impact on juvenile idiopathic arthritis - Eighteen years of follow-up in the population-based Nordic Juvenile Idiopathic Arthritis Cohort
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Diffuse large B cell lymphoma in rheumatoid arthritis patients is associated with elevated B-cell driving factors including CXCL13

Euler, Nora; Hellbacher, Erik; af Klint, Erik; Hansson, Monika et al.

Ingår i Clinical Immunology, 2025

• DOI för Diffuse large B cell lymphoma in rheumatoid arthritis patients is associated with elevated B-cell driving factors including CXCL13
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Epidemiology of patients with moderate-to-severe SLE in Sweden

Frodlund, Martina; Leonard, Dag; Haugli-Stephens, Thomas; Remkus, Lauren et al.

Ingår i Lupus Science and Medicine, 2025

• DOI för Epidemiology of patients with moderate-to-severe SLE in Sweden
• Ladda ner fulltext (pdf) av Epidemiology of patients with moderate-to-severe SLE in Sweden

A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease

Fugmann, Cecilia; Reid, Sarah; Pucholt, Pascal; Kvarnström, Marika et al.

Ingår i Rheumatology, s. 4341-4346, 2025

• DOI för A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease
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The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis

Hellbacher, Erik; van Hoef, Vincent; Johansson, Alina; Knight, Ann et al.

Ingår i Frontiers in Immunology, 2025

• DOI för The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis
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Targeted proteomics identifies differentially expressed proteins in Sjögren's disease with incident lymphoma

Imgenberg-Kreuz, Juliana; Fugmann, Cecilia; Molin, Anna-Maja; Backlin, Carin et al.

Ingår i RMD Open, 2025

• DOI för Targeted proteomics identifies differentially expressed proteins in Sjögren's disease with incident lymphoma
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Autoantibody-defined subsets of patients with systemic lupus erythematosus associate with clinical manifestations, NCF2, and HLA DR3-DQ2 genotypes

Leffers, Henrik Christian Bidstrup; Troldborg, Anne; Andersen, Martin; Sanchez, Ana Cristina Gonzalez et al.

Ingår i Translational Research, s. 29-37, 2025

• DOI för Autoantibody-defined subsets of patients with systemic lupus erythematosus associate with clinical manifestations, NCF2, and HLA DR3-DQ2 genotypes
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In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody-Associated Vasculitides Identifies Distinct Clinical Phenotypes

Lindberg, Hanna; Knight, Ann; Hellbacher, Erik; Norling, Olof et al.

Ingår i ACR Open Rheumatology, 2025

• DOI för In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody-Associated Vasculitides Identifies Distinct Clinical Phenotypes
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Rare and common single nucleotide variants in childhood-onset systemic lupus erythematosus

Sayadi, Ahmed; Sandling, Johanna K.; Eloranta, Maija-Leena; Jönsen, Andreas et al.

Ingår i Lupus Science and Medicine, 2025

• DOI för Rare and common single nucleotide variants in childhood-onset systemic lupus erythematosus
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Serum calprotectin correlates stronger with inflammation and disease activity in ACPA positive than ACPA negative rheumatoid arthritis

Sejersen, Kristina; Weitoft, Tomas; Knight, Ann; Lysholm, Jörgen et al.

Ingår i Rheumatology, s. 126-132, 2025

• DOI för Serum calprotectin correlates stronger with inflammation and disease activity in ACPA positive than ACPA negative rheumatoid arthritis
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Characteristics That Predict Psoriatic Arthritis by the Classification Criteria for Psoriatic Arthritis in Patients With Juvenile Idiopathic Arthritis 18 Years After Disease Onset

Szentpetery, Agnes; Glerup, Mia; Aalto, Kristiina; Arnstad, Ellen D. et al.

Ingår i ACR Open Rheumatology, 2025

• DOI för Characteristics That Predict Psoriatic Arthritis by the Classification Criteria for Psoriatic Arthritis in Patients With Juvenile Idiopathic Arthritis 18 Years After Disease Onset
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Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE

Torell, Agnes; Andersson, Kerstin; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Ingår i Lupus Science and Medicine, 2025

• DOI för Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE
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Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes

Vestin, Holme; Oparina, Nina Y.; Eloranta, Maija-Leena; Frodlund, Martina et al.

Ingår i RMD Open, 2025

• DOI för Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes
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Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

Wiley, Mandi M.; Radziszewski, Marcin; Khatri, Bhuwan; Joachims, Michelle L. et al.

Ingår i Annals of the Rheumatic Diseases, s. 1512-1527, 2025

• DOI för Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

A chromosome-level assembly of the seed beetle Callosobruchus maculatus genome with annotation of its repetitive elements

Arnqvist, Göran; Westerberg, Ivar; Galbraith, James; Sayadi, Ahmed et al.

Ingår i G3, 2024

• DOI för A chromosome-level assembly of the seed beetle Callosobruchus maculatus genome with annotation of its repetitive elements
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Multi-modal single cell sequencing of B cells in primary Sjögren's Syndrome.

Arvidsson, Gustav; Czarnewski, Paulo; Johansson, Alina; Raine, Amanda et al.

Ingår i Arthritis & Rheumatology, s. 255-267, 2024

• DOI för Multi-modal single cell sequencing of B cells in primary Sjögren's Syndrome.
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Examining the biological pathways underlying clinical heterogeneity in Sjogren's syndrome: proteomic and network analysis

Berry, Joe Scott; Tarn, Jessica; Casement, John; Duret, Pierre-Marie et al.

Ingår i Annals of the Rheumatic Diseases, s. 88-95, 2024

• DOI för Examining the biological pathways underlying clinical heterogeneity in Sjogren's syndrome: proteomic and network analysis

Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality-a national cohort study

Frodlund, Martina; Jonsen, Andreas; Remkus, Lauren; Telg, Gunilla et al.

Ingår i Rheumatology, s. 1104-1112, 2024

• DOI för Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality-a national cohort study
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A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile

Lindelöf, Linnea; Rantapää-Dahlqvist, Solbritt; Lundtoft, Christian; Sandling, Johanna K. et al.

Ingår i Journal of Autoimmunity, 2024

• DOI för A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile
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Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies: A longitudinal study

Lodin, Karin; Espinosa-Ortega, Fabricio; Dastmalchi, Maryam; Vencovsky, Jiri et al.

Ingår i Seminars in Arthritis & Rheumatism, 2024

• DOI för Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies: A longitudinal study
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The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population

Lundtoft, Christian; Knight, Ann; Meadows, Jennifer; Karlsson, Åsa et al.

Ingår i RMD Open, 2024

• DOI för The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population
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Tofacitinib real-world experience in ulcerative colitis in Finland (FinTofUC): a retrospective non-interventional multicenter patient chart data study

Molander, Pauliina; Kosunen, Mikko; Eronen, Heli; Tillonen, Jyrki et al.

Ingår i Scandinavian Journal of Gastroenterology, s. 425-432, 2024

• DOI för Tofacitinib real-world experience in ulcerative colitis in Finland (FinTofUC): a retrospective non-interventional multicenter patient chart data study
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Comparative Genomic Analysis of the Pattern of Evolution of Male and Female Reproductive Proteins in Seed Beetles

Papachristos, Konstantinos; Sayadi, Ahmed; Arnqvist, Göran

Ingår i Genome Biology and Evolution, 2024

• DOI för Comparative Genomic Analysis of the Pattern of Evolution of Male and Female Reproductive Proteins in Seed Beetles
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Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Stockfelt, Marit; Torell, Agnes; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Ingår i Rheumatology, s. 1469-1475, 2024

• DOI för Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus
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An exploratory study of the damage markers NfL, GFAP, and t-Tau, in cerebrospinal fluid and other findings from a patient cohort enriched for suspected autoimmune psychiatric disease

Syk, Mikaela; Tornvind, Emma; Gallwitz, Maike; Fällmar, David et al.

Ingår i Translational Psychiatry, 2024

• DOI för An exploratory study of the damage markers NfL, GFAP, and t-Tau, in cerebrospinal fluid and other findings from a patient cohort enriched for suspected autoimmune psychiatric disease
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Genome-wide investigation of persistence with methotrexate treatment in early rheumatoid arthritis

Sysojev, Anton Öberg; Saevarsdottir, Saedis; Diaz-Gallo, Lina-Marcela; Silberberg, Gilad N. et al.

Ingår i Rheumatology, s. 1221-1229, 2024

• DOI för Genome-wide investigation of persistence with methotrexate treatment in early rheumatoid arthritis
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Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy

Torell, Agnes; Stockfelt, Marit; Blennow, Kaj; Zetterberg, Henrik et al.

Ingår i Arthritis Research & Therapy, 2024

• DOI för Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy
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Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis

Turcinov, Sara; Sharma, Ravi Kumar; De Vries, Charlotte; Cîrciumaru, Alexandra et al.

Ingår i RMD Open, 2024

• DOI för Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis
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Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans

Wang, Sailan; Nikamo, Pernilla; Laasonen, Leena; Gudbjornsson, Bjorn et al.

Ingår i EMBO Molecular Medicine, s. 596-615, 2024

• DOI för Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans
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Exhaled Nitric Oxide Reflects the Immune Reactions of the Airways in Early Rheumatoid Arthritis

Weitoft, Tomas; Rönnelid, Johan; Lind, Anders; de Vries, Charlotte et al.

Ingår i Biomedicines, 2024

• DOI för Exhaled Nitric Oxide Reflects the Immune Reactions of the Airways in Early Rheumatoid Arthritis
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Risks and treatment related aspects of COVID-19 infection in patients with ANCA-associated vasculitis

Antovic, A.; Bruchfeld, A.; Ekland, J.; Lovstrom, B. et al.

Ingår i Scandinavian Journal of Rheumatology, s. 418-423, 2023

• DOI för Risks and treatment related aspects of COVID-19 infection in patients with ANCA-associated vasculitis
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